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Key Facts: PA MPJE Exam

120

Exam Questions

100 scored + 20 pretest

Pass/Fail

Result Reporting

NABP

2.5 hrs

Time Limit

NABP

CE Hours

Per renewal period

1,500 hours

Intern Hours Required

PA Board

The PA MPJE applies federal and Pennsylvania pharmacy law using the current NABP blueprint: Licensure and Personnel 22%, Pharmacist Practice 33%, Dispensing Requirements 24%, and Pharmacy Operations 21%. NABP administers 120 adaptive selected-response questions in 2.5 hours and reports results only as Pass or Fail.

Sample PA MPJE Practice Questions

Try these sample questions to review concepts for the PA MPJE exam. Each question includes a detailed explanation. Start the interactive quiz above for the full 319+ question experience with AI tutoring.

1Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?

A.Schedule I

B.Schedule II

C.Schedule III

D.Schedule IV

Explanation: Schedule I substances have a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision. Examples include heroin, LSD, and MDMA. Pharmacists cannot dispense Schedule I substances under normal practice.

2A DEA Form 222 is required for the transfer of which schedule of controlled substances between registrants?

A.Schedule II only

B.Schedules II and III

C.Schedules III through V

D.All controlled substances

Explanation: DEA Form 222 (or its electronic equivalent under CSOS) is required for the distribution and transfer of Schedule II controlled substances between DEA registrants. Schedules III-V can be transferred using invoices with specific record-keeping requirements.

3Under federal law, what is the maximum number of refills allowed for a Schedule III controlled substance prescription?

A.No refills allowed

B.Up to 3 refills within 6 months

C.Up to 5 refills within 6 months

D.Up to 5 refills within 1 year

Explanation: Federal law allows up to 5 refills for Schedule III-V controlled substance prescriptions within 6 months from the date the prescription was issued. Schedule II prescriptions cannot be refilled. After 6 months or 5 refills, a new prescription is required.

4The Durham-Humphrey Amendment of 1951 established which key distinction in drug classification?

A.Generic vs. brand-name drugs

B.Prescription (legend) vs. over-the-counter drugs

C.Controlled vs. non-controlled substances

D.Biological vs. chemical drugs

Explanation: The Durham-Humphrey Amendment to the Federal Food, Drug, and Cosmetic Act (FDCA) established the distinction between prescription (legend) drugs and over-the-counter (OTC) drugs. It required that certain drugs be dispensed only with a valid prescription and bear the legend 'Caution: Federal law prohibits dispensing without prescription.'

5Under the Poison Prevention Packaging Act (PPPA), which of the following medications is EXEMPT from child-resistant packaging requirements?

A.Acetaminophen tablets

B.Sublingual nitroglycerin tablets

C.Amoxicillin suspension

D.Hydrocodone/acetaminophen tablets

Explanation: Sublingual nitroglycerin tablets are exempt from child-resistant packaging under the PPPA because they require immediate access during cardiac emergencies. Other exemptions include oral contraceptives in manufacturer dispensing packages, certain hormone replacement therapy, and isosorbide dinitrate sublingual tablets.

6What is the primary purpose of the FDA's Risk Evaluation and Mitigation Strategies (REMS) program?

A.To reduce drug manufacturing costs

B.To ensure the benefits of a drug outweigh its risks

C.To speed up the drug approval process

D.To establish drug pricing guidelines

Explanation: REMS are drug safety programs required by the FDA for certain medications with serious safety concerns. They help ensure the benefits of a medication outweigh its risks. REMS may include medication guides, communication plans, and Elements to Assure Safe Use (ETASU) such as prescriber certification and patient registries.

7Under the Combat Methamphetamine Epidemic Act (CMEA), what is the maximum amount of pseudoephedrine a customer can purchase in a 30-day period?

A.3.6 grams

B.7.5 grams

C.9 grams

D.15 grams

Explanation: The CMEA limits pseudoephedrine purchases to 3.6 grams per day and 9 grams per 30-day period for retail transactions. Mail-order purchases are limited to 7.5 grams per 30-day period. Retailers must keep a logbook of all pseudoephedrine sales and products must be kept behind the counter.

8A pharmacist receives a prescription for a Schedule II controlled substance dated 45 days ago. Under federal law, this prescription:

A.Must be filled within 30 days

B.May be filled as there is no federal time limit

C.Cannot be filled because it has expired

D.May only be partially filled

Explanation: Federal law does not impose a specific time limit on filling Schedule II prescriptions. However, individual states may impose their own time limits, and the pharmacist must follow the stricter of state or federal requirements. The pharmacist must use professional judgment to determine whether the prescription is still valid based on the patient's needs and state law requirements.

9Under the Health Insurance Portability and Accountability Act (HIPAA), which of the following is NOT considered protected health information (PHI)?

A.A patient's prescription history

B.A patient's date of birth

C.De-identified aggregate prescription data

D.A patient's home address

Explanation: De-identified data is not considered PHI under HIPAA. PHI includes individually identifiable health information such as names, dates, addresses, Social Security numbers, and medical records. Data that has been properly de-identified according to HIPAA standards (Safe Harbor or Expert Determination method) is not subject to HIPAA restrictions.

10Under the Drug Supply Chain Security Act (DSCSA), what must be included with each transaction of a prescription drug between trading partners?

A.Only the drug name and NDC number

B.Transaction information, transaction history, and transaction statement

C.DEA Form 222 and invoice

D.Certificate of analysis and lot number only

Explanation: The DSCSA requires three types of documentation for each prescription drug transaction: transaction information (drug details, date, entities involved), transaction history (previous ownership chain), and transaction statement (attestation that the trading partner meets DSCSA requirements). This supports drug supply chain integrity and helps prevent counterfeit drugs.

About the PA MPJE Exam

The PA MPJE tests knowledge of federal pharmacy law and Pennsylvania-specific pharmacy regulations. Required alongside the NAPLEX for pharmacist licensure in Pennsylvania.

Exam sponsor: NABP / Pennsylvania State Board of Pharmacy. The requirements and fees below concern the certification or admission exam, separate from our free practice resources.

Questions

120 questions

Time Limit

2.5 hours

Passing Score

Pass/Fail; no scaled numerical score reported

Exam / Certification Fees

$270 to NABP ($100 nonrefundable eligibility application + $170 exam purchase); Pennsylvania Board fees are separate

Exam sponsor website

Reported exam pass rate: Not publicly reported. Exam sponsor website

Fees, eligibility, and exam policies can change. Confirm them with the exam sponsor before applying or paying.

Official sources

Our practice resources: topics covered

We aim to reflect publicly available exam outlines and topic information in our study resources. Coverage, format, and difficulty may differ from the actual exam, and we cannot guarantee that every detail is accurate or current. Confirm exam requirements, fees, and policies with the official exam sponsor.

22%

Licensure & Personnel

Pharmacist qualifications, intern/technician requirements, license renewal, disciplinary actions

33%

Pharmacist Practice

Prescription requirements, counseling, collaborative practice, immunizations

24%

Dispensing Requirements

Generic substitution, prescription transfers, DUR, labeling, PA PDMP compliance

21%

Pharmacy Operations

Controlled substance records, compounding, pharmacy permits, automated dispensing

Preparing for the PA MPJE Exam

What You Need to Know

Passing score: Pass/Fail; no scaled numerical score reported
Exam length: 120 questions
Time limit: 2.5 hours
Exam / certification fees: $270 to NABP ($100 nonrefundable eligibility application + $170 exam purchase); Pennsylvania Board fees are separate Official sources

Using Our Practice Resources

Work through all 319 available questions
Review every answer and explanation
Track weak areas and revisit them
Use our AI tutor for tough concepts

PA MPJE: Suggested Study Strategy

1Master 49 Pa. Code Chapter 27 and the Pharmacy Act (Act 699) and Pennsylvania pharmacy regulations

2Know PA PDMP (Pennsylvania Prescription Drug Monitoring Program) requirements for controlled substance dispensing

3Study Pennsylvania renewal requirements using the current Board instructions, including 30 contact hours per biennial renewal and required topic-specific education

4Understand current technician and trainee registration, supervision, written-protocol, and duty limits

5Distinguish Pennsylvania PDMP reporting duties from the specific situations that trigger a dispenser query

Frequently Asked Questions

What is the PA MPJE exam format?

The PA MPJE is a computer-adaptive test with 120 questions (100 scored and 20 unscored pretest) in 2.5 hours. NABP reports results only as Pass or Fail and does not report a scaled numerical score.

What Pennsylvania-specific topics are tested?

Key topics include 49 Pa. Code Chapter 27 and the Pharmacy Act, controlled-substance rules, PDMP reporting and conditional dispenser queries, licensure and personnel, counseling, dispensing, records, compounding, permits, and pharmacy operations.

How do I register for the PA MPJE?

Create an NABP e-Profile, obtain Pennsylvania Board eligibility, pay NABP's $100 application and $170 exam fees, then schedule through Pearson VUE. Pennsylvania Board fees are separate.

What happens if I fail the PA MPJE?

You must wait at least 30 days before retaking. Reapplication and fees are required for each attempt.

How long should I study for the PA MPJE?

Most candidates study 2-4 weeks. Focus on 49 Pa. Code Chapter 27 and the Pharmacy Act (Act 699), federal law, and scenario-based practice questions.

Does Pennsylvania require EPCS?

Pennsylvania generally requires practitioners other than veterinarians to issue Schedule II-V controlled-substance prescriptions electronically under Act 96 of 2018, subject to the Act's exceptions and applicable federal EPCS requirements.

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