299+ Free MA MPJE Practice Questions

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Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?

Schedule I

Schedule II

Schedule III

Schedule IV

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Free MPJE Practice Test by State 2026: 5,000+ Pharmacy Law Questions18 min read

2026 Statistics

Key Facts: MA MPJE Exam

120

Questions

100 scored + 20 pretest

Passing Score

NABP scaled score

2.5h

Exam Time

Pearson VUE

1:2

Tech Ratio

MA max

20h/yr

CE Required

MA renewal

$270

Exam Fee

NABP 2026

The MA MPJE covers federal pharmacy law (DEA, FDA, CSA, HIPAA) and Massachusetts-specific regulations including MassPAT PMP program, 2:1 technician ratio, 7-day initial opioid supply limit, mandatory PMP check before dispensing controlled substances, collaborative practice, must-dispense generic substitution law, 1:2 technician ratio, and 20h/yr CE requirement.

Sample MA MPJE Practice Questions

Try these sample questions to test your MA MPJE exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 299+ question experience with AI tutoring.

1Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?

A.Schedule I

B.Schedule II

C.Schedule III

D.Schedule IV

Explanation: Schedule I substances have a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision. Examples include heroin, LSD, and MDMA.

2A DEA Form 222 is required for the transfer of which schedule of controlled substances between registrants?

A.Schedule II only

B.Schedules II and III

C.Schedules III through V

D.All controlled substances

Explanation: DEA Form 222 (or its electronic equivalent under CSOS) is required for the distribution and transfer of Schedule II controlled substances between DEA registrants.

3Under federal law, what is the maximum number of refills allowed for a Schedule III controlled substance prescription?

A.No refills allowed

B.Up to 3 refills within 6 months

C.Up to 5 refills within 6 months

D.Up to 5 refills within 1 year

Explanation: Federal law allows up to 5 refills for Schedule III-V controlled substance prescriptions within 6 months from the date the prescription was issued.

4The Durham-Humphrey Amendment of 1951 established which key distinction in drug classification?

A.Generic vs. brand-name drugs

B.Prescription (legend) vs. over-the-counter drugs

C.Controlled vs. non-controlled substances

D.Biological vs. chemical drugs

Explanation: The Durham-Humphrey Amendment to the Federal Food, Drug, and Cosmetic Act established the distinction between prescription (legend) drugs and over-the-counter (OTC) drugs.

5Which federal law requires pharmacists to offer counseling to Medicaid patients on new prescriptions?

A.HIPAA

B.OBRA '90

C.DSCSA

D.Kefauver-Harris Amendment

Explanation: The Omnibus Budget Reconciliation Act of 1990 (OBRA '90) requires pharmacists to offer counseling to Medicaid patients receiving new prescriptions and to perform prospective drug utilization review (DUR).

6Under the Poison Prevention Packaging Act (PPPA), which medication is exempt from child-resistant packaging?

A.Amoxicillin suspension

B.Sublingual nitroglycerin

C.Lisinopril tablets

D.Metformin tablets

Explanation: Sublingual nitroglycerin is exempt from child-resistant packaging under the PPPA due to the need for immediate emergency access.

7What is the maximum days' supply of a Schedule II controlled substance that can be prescribed via emergency oral prescription under federal law?

A.72-hour supply

B.7-day supply

C.14-day supply

D.30-day supply

Explanation: In an emergency, a pharmacist may dispense a Schedule II controlled substance based on an oral prescription, limited to a quantity adequate for the emergency period (typically 72 hours). A written follow-up is required within 7 days.

8Under HIPAA, which of the following is considered protected health information (PHI)?

A.De-identified aggregate prescription data

B.A patient's prescription fill history linked to their name

C.Published clinical trial results

D.General drug interaction information

Explanation: PHI under HIPAA includes any individually identifiable health information, including prescription records linked to a patient's name.

9The Drug Supply Chain Security Act (DSCSA) requires pharmacies to maintain transaction records for how long?

A.2 years

B.4 years

C.6 years

D.10 years

Explanation: Under the DSCSA, pharmacies must maintain transaction information, history, and statements for at least 6 years from the date of the transaction.

10A DEA registrant must take an initial inventory of controlled substances on what date?

A.Within 30 days of opening

B.On the date the registrant first engages in controlled substance activity

C.Within 90 days of DEA registration

D.On January 1 of each year

Explanation: A DEA registrant must take an initial inventory on the date the registrant first engages in the manufacture, distribution, or dispensing of controlled substances.

About the MA MPJE Exam

The Massachusetts MPJE tests knowledge of federal pharmacy law and Massachusetts-specific pharmacy regulations under MGL Chapter 112, Sections 24-42D (Pharmacy Practice Act). Required alongside the NAPLEX for pharmacist licensure in Massachusetts.

Questions

120 scored questions

Time Limit

2.5 hours

Passing Score

75 (scaled score)

Exam Fee

$270 (NABP / Massachusetts Board of Registration in Pharmacy)

MA MPJE Exam Content Outline

22%

Licensure & Personnel

Pharmacist qualifications, intern/technician requirements, license renewal, disciplinary actions

33%

Pharmacist Practice

Prescription requirements, counseling, controlled substance rules, collaborative practice agreements

24%

Dispensing Requirements

Generic substitution, prescription transfers, DUR, labeling, PDMP checking

21%

Pharmacy Operations

Controlled substance records, compounding standards, pharmacy permits, automated dispensing

How to Pass the MA MPJE Exam

What You Need to Know

Passing score: 75 (scaled score)
Exam length: 120 questions
Time limit: 2.5 hours
Exam fee: $270

Keys to Passing

Complete 500+ practice questions
Score 80%+ consistently before scheduling
Focus on highest-weighted sections
Use our AI tutor for tough concepts

MA MPJE Study Tips from Top Performers

1Study MGL Chapter 112, Sections 24-42D (Pharmacy Practice Act) for Massachusetts-specific pharmacy regulations

2Master DEA controlled substance schedules, forms (222, 106, 41), and corresponding responsibility

3Know Massachusetts PDMP requirements and mandatory query triggers for Schedule II-V substances

4Review Massachusetts naloxone access laws and collaborative practice agreements

5Understand federal vs. state law conflicts — the more restrictive law prevails

Frequently Asked Questions

What is the MA MPJE passing score?

The Massachusetts MPJE requires a scaled score of 75. The exam has 120 questions (100 scored, 20 pretest) over 2.5 hours at Pearson VUE.

What Massachusetts laws are tested?

The MA MPJE covers MGL Chapter 112, Sections 24-42D (Pharmacy Practice Act), MGL Chapter 94C (Controlled Substances Act), Massachusetts Board of Registration in Pharmacy rules, PDMP requirements, and state-specific dispensing regulations.

What is the technician ratio in Massachusetts?

Massachusetts allows a 1:2 pharmacist-to-technician ratio. Technicians must be registered with the Massachusetts Board of Registration in Pharmacy and work under direct pharmacist supervision.

How many CE hours does Massachusetts require?

Massachusetts requires 20h/yr of continuing education per renewal period. CE must be ACPE-accredited.

Does Massachusetts require PDMP checks?

Yes, Massachusetts requires pharmacists to check the PDMP before dispensing Schedule II-V controlled substances.