299+ Free IL MPJE Practice Questions

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Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?

Schedule I

Schedule II

Schedule III

Schedule IV

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Free MPJE Practice Test by State 2026: 5,000+ Pharmacy Law Questions18 min read

2026 Statistics

Key Facts: IL MPJE Exam

120

Questions

100 scored + 20 pretest

Passing Score

NABP scaled score

2.5h

Exam Time

Pearson VUE

No fixed ratio (pharmacist discretion)

Tech Ratio

IL max

30h/2yr

CE Required

IL renewal

$270

Exam Fee

NABP 2026

The IL MPJE covers federal pharmacy law (DEA, FDA, CSA, HIPAA) and Illinois-specific regulations including no fixed tech ratio (pharmacist judgment), mandatory e-prescribing for controlled substances, PMP mandatory checks, self-service pharmacy kiosks, automated pharmacy systems, No fixed ratio (pharmacist discretion) technician ratio, and 30h/2yr CE requirement.

Sample IL MPJE Practice Questions

Try these sample questions to test your IL MPJE exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 299+ question experience with AI tutoring.

1Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?

A.Schedule I

B.Schedule II

C.Schedule III

D.Schedule IV

Explanation: Schedule I substances have a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision. Examples include heroin, LSD, and MDMA.

2A DEA Form 222 is required for the transfer of which schedule of controlled substances between registrants?

A.Schedule II only

B.Schedules II and III

C.Schedules III through V

D.All controlled substances

Explanation: DEA Form 222 (or its electronic equivalent under CSOS) is required for the distribution and transfer of Schedule II controlled substances between DEA registrants.

3Under federal law, what is the maximum number of refills allowed for a Schedule III controlled substance prescription?

A.No refills allowed

B.Up to 3 refills within 6 months

C.Up to 5 refills within 6 months

D.Up to 5 refills within 1 year

Explanation: Federal law allows up to 5 refills for Schedule III-V controlled substance prescriptions within 6 months from the date the prescription was issued.

4The Durham-Humphrey Amendment of 1951 established which key distinction in drug classification?

A.Generic vs. brand-name drugs

B.Prescription (legend) vs. over-the-counter drugs

C.Controlled vs. non-controlled substances

D.Biological vs. chemical drugs

Explanation: The Durham-Humphrey Amendment to the Federal Food, Drug, and Cosmetic Act established the distinction between prescription (legend) drugs and over-the-counter (OTC) drugs.

5Which federal law requires pharmacists to offer counseling to Medicaid patients on new prescriptions?

A.HIPAA

B.OBRA '90

C.DSCSA

D.Kefauver-Harris Amendment

Explanation: The Omnibus Budget Reconciliation Act of 1990 (OBRA '90) requires pharmacists to offer counseling to Medicaid patients receiving new prescriptions and to perform prospective drug utilization review (DUR).

6Under the Poison Prevention Packaging Act (PPPA), which medication is exempt from child-resistant packaging?

A.Amoxicillin suspension

B.Sublingual nitroglycerin

C.Lisinopril tablets

D.Metformin tablets

Explanation: Sublingual nitroglycerin is exempt from child-resistant packaging under the PPPA due to the need for immediate emergency access.

7What is the maximum days' supply of a Schedule II controlled substance that can be prescribed via emergency oral prescription under federal law?

A.72-hour supply

B.7-day supply

C.14-day supply

D.30-day supply

Explanation: In an emergency, a pharmacist may dispense a Schedule II controlled substance based on an oral prescription, limited to a quantity adequate for the emergency period (typically 72 hours). A written follow-up is required within 7 days.

8Under HIPAA, which of the following is considered protected health information (PHI)?

A.De-identified aggregate prescription data

B.A patient's prescription fill history linked to their name

C.Published clinical trial results

D.General drug interaction information

Explanation: PHI under HIPAA includes any individually identifiable health information, including prescription records linked to a patient's name.

9The Drug Supply Chain Security Act (DSCSA) requires pharmacies to maintain transaction records for how long?

A.2 years

B.4 years

C.6 years

D.10 years

Explanation: Under the DSCSA, pharmacies must maintain transaction information, history, and statements for at least 6 years from the date of the transaction.

10A DEA registrant must take an initial inventory of controlled substances on what date?

A.Within 30 days of opening

B.On the date the registrant first engages in controlled substance activity

C.Within 90 days of DEA registration

D.On January 1 of each year

Explanation: A DEA registrant must take an initial inventory on the date the registrant first engages in the manufacture, distribution, or dispensing of controlled substances.

About the IL MPJE Exam

The Illinois MPJE tests knowledge of federal pharmacy law and Illinois-specific pharmacy regulations under 225 ILCS 85 (Illinois Pharmacy Practice Act). Required alongside the NAPLEX for pharmacist licensure in Illinois.

Questions

120 scored questions

Time Limit

2.5 hours

Passing Score

75 (scaled score)

Exam Fee

$270 (NABP / Illinois Department of Financial and Professional Regulation (DFPR))

IL MPJE Exam Content Outline

22%

Licensure & Personnel

Pharmacist qualifications, intern/technician requirements, license renewal, disciplinary actions

33%

Pharmacist Practice

Prescription requirements, counseling, controlled substance rules, collaborative practice agreements

24%

Dispensing Requirements

Generic substitution, prescription transfers, DUR, labeling, PDMP checking

21%

Pharmacy Operations

Controlled substance records, compounding standards, pharmacy permits, automated dispensing

How to Pass the IL MPJE Exam

What You Need to Know

Passing score: 75 (scaled score)
Exam length: 120 questions
Time limit: 2.5 hours
Exam fee: $270

Keys to Passing

Complete 500+ practice questions
Score 80%+ consistently before scheduling
Focus on highest-weighted sections
Use our AI tutor for tough concepts

IL MPJE Study Tips from Top Performers

1Study 225 ILCS 85 (Illinois Pharmacy Practice Act) for Illinois-specific pharmacy regulations

2Master DEA controlled substance schedules, forms (222, 106, 41), and corresponding responsibility

3Know Illinois PDMP requirements and mandatory query triggers for Schedule II-V substances

4Review Illinois naloxone access laws and collaborative practice agreements

5Understand federal vs. state law conflicts — the more restrictive law prevails

Frequently Asked Questions

What is the IL MPJE passing score?

The Illinois MPJE requires a scaled score of 75. The exam has 120 questions (100 scored, 20 pretest) over 2.5 hours at Pearson VUE.

What Illinois laws are tested?

The IL MPJE covers 225 ILCS 85 (Illinois Pharmacy Practice Act), 720 ILCS 570 (Illinois Controlled Substances Act), Illinois Department of Financial and Professional Regulation (DFPR) rules, PDMP requirements, and state-specific dispensing regulations.

What is the technician ratio in Illinois?

Illinois allows a No fixed ratio (pharmacist discretion) pharmacist-to-technician ratio. Technicians must be registered with the Illinois Department of Financial and Professional Regulation (DFPR) and work under direct pharmacist supervision.

How many CE hours does Illinois require?

Illinois requires 30h/2yr of continuing education per renewal period. CE must be ACPE-accredited.

Does Illinois require PDMP checks?

Yes, Illinois requires pharmacists to check the PDMP before dispensing Schedule II-V controlled substances.