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Key Facts: NC MPJE Exam

120

Questions

100 scored + 20 pretest

Passing Score

NABP scaled score

2.5h

Exam Time

Pearson VUE

2:1

Tech Ratio

NC max

15h/yr

CE Required

NC annual

$250

Exam Fee

NABP 2026

The NC MPJE covers federal pharmacy law (DEA, FDA, CSA, HIPAA) and NC-specific regulations including CSRS mandatory checks, Clinical Pharmacist Practitioner authority, immunization protocols, 15h/yr CE, and 2:1 technician ratio.

Sample NC MPJE Practice Questions

Try these sample questions to review concepts for the NC MPJE exam. Each question includes a detailed explanation. Start the interactive quiz above for the full 299+ question experience with AI tutoring.

1Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?

A.Schedule I

B.Schedule II

C.Schedule III

D.Schedule IV

Explanation: Schedule I substances have a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision. Examples include heroin, LSD, and MDMA. Pharmacists cannot dispense Schedule I substances under normal practice.

2A DEA Form 222 is required for the transfer of which schedule of controlled substances between registrants?

A.Schedule II only

B.Schedules II and III

C.Schedules III through V

D.All controlled substances

Explanation: DEA Form 222 (or its electronic equivalent under CSOS) is required for the distribution and transfer of Schedule II controlled substances between DEA registrants. Schedules III-V can be transferred using invoices with specific record-keeping requirements.

3Under federal law, what is the maximum number of refills allowed for a Schedule III controlled substance prescription?

A.No refills allowed

B.Up to 3 refills within 6 months

C.Up to 5 refills within 6 months

D.Up to 5 refills within 1 year

Explanation: Federal law allows up to 5 refills for Schedule III-V controlled substance prescriptions within 6 months from the date the prescription was issued. Schedule II prescriptions cannot be refilled.

4The Durham-Humphrey Amendment of 1951 established which key distinction in drug classification?

A.Generic vs. brand-name drugs

B.Prescription (legend) vs. over-the-counter drugs

C.Controlled vs. non-controlled substances

D.Biological vs. chemical drugs

Explanation: The Durham-Humphrey Amendment to the Federal Food, Drug, and Cosmetic Act established the distinction between prescription (legend) drugs and over-the-counter (OTC) drugs, requiring certain drugs to bear the legend 'Caution: Federal law prohibits dispensing without prescription.'

5Under HIPAA, which of the following is considered a permitted disclosure of protected health information (PHI) without patient authorization?

A.Sharing prescription data with a marketing company

B.Disclosing PHI for treatment, payment, or healthcare operations

C.Posting patient medication lists on social media for educational purposes

D.Providing medication history to a patient's employer upon request

Explanation: HIPAA permits disclosure of PHI without patient authorization for treatment, payment, and healthcare operations (TPO). All other disclosures generally require written patient authorization unless specifically exempted by law.

6The Poison Prevention Packaging Act (PPPA) requires child-resistant containers for most prescription drugs. Which of the following is exempt from this requirement?

A.Oral contraceptives dispensed in manufacturer's compliance packaging

B.All Schedule II controlled substances

C.Any medication for patients over age 50

D.Antibiotics in liquid form

Explanation: Oral contraceptives in manufacturer's mnemonic (compliance) packaging are exempt from PPPA child-resistant packaging requirements. Other exemptions include sublingual nitroglycerin, certain corticosteroid inhalers, and situations where the prescriber or patient requests non-child-resistant packaging.

7Under the Combat Methamphetamine Epidemic Act (CMEA), pseudoephedrine sales are limited to what maximum quantity per 30-day period?

A.3.6 grams

B.7.5 grams

C.9 grams

D.15 grams

Explanation: The CMEA limits pseudoephedrine purchases to 9 grams per 30-day period and 3.6 grams per day. Products must be kept behind the counter or in locked cabinets, and purchasers must present identification and sign a logbook.

8Under OBRA '90, pharmacists are required to perform which of the following for Medicaid patients?

A.Free medication delivery

B.Drug utilization review (DUR) and patient counseling

C.Annual physical examinations

D.Genetic testing before dispensing

Explanation: OBRA '90 (Omnibus Budget Reconciliation Act of 1990) requires pharmacists to conduct prospective drug utilization review (DUR) and offer counseling to Medicaid patients on new prescriptions. Most states have extended this requirement to all patients.

9The FDA's Risk Evaluation and Mitigation Strategies (REMS) program may require which of the following?

A.Mandatory genetic testing for all patients

B.Medication guides, communication plans, or elements to assure safe use (ETASU)

C.Automatic substitution with generic equivalents

D.Prior authorization from the DEA before dispensing

Explanation: REMS may include medication guides, communication plans, and Elements to Assure Safe Use (ETASU) such as prescriber certification, patient registries, or restricted distribution systems. iPLEDGE for isotretinoin is a well-known example of a REMS with ETASU.

10Under the Drug Supply Chain Security Act (DSCSA), pharmacies must maintain transaction records for prescription drugs for how long?

A.1 year

B.3 years

C.6 years

D.10 years

Explanation: The DSCSA requires trading partners, including pharmacies, to maintain transaction information (TI), transaction history (TH), and transaction statements (TS) for at least 6 years to ensure drug supply chain integrity and enable tracing of suspect or illegitimate products.

About the NC MPJE Exam

The North Carolina MPJE tests knowledge of federal pharmacy law and NC-specific pharmacy regulations under NCGS Chapter 90. Required alongside the NAPLEX for pharmacist licensure in North Carolina.

Exam sponsor: NABP / NC Board of Pharmacy. The requirements and fees below concern the certification or admission exam, separate from our free practice resources.

Questions

120 questions

Time Limit

2.5 hours

Passing Score

75 (scaled score)

Exam / Certification Fees

$250

Exam sponsor website

Reported exam pass rate: Not publicly reported. Exam sponsor website

Fees, eligibility, and exam policies can change. Confirm them with the exam sponsor before applying or paying.

Official sources

NABP / NC Board of Pharmacy: official exam information

Our practice resources: topics covered

We aim to reflect publicly available exam outlines and topic information in our study resources. Coverage, format, and difficulty may differ from the actual exam, and we cannot guarantee that every detail is accurate or current. Confirm exam requirements, fees, and policies with the official exam sponsor.

22%

Licensure & Personnel

Pharmacist qualifications, intern/technician requirements, license renewal, Clinical Pharmacist Practitioner status

33%

Pharmacist Practice

Prescription requirements, counseling, controlled substance rules, collaborative practice agreements

24%

Dispensing Requirements

Generic substitution, prescription transfers, DUR, labeling, CSRS checking

21%

Pharmacy Operations

Controlled substance records, compounding standards, pharmacy permits, automated dispensing

Preparing for the NC MPJE Exam

What You Need to Know

Passing score: 75 (scaled score)
Exam length: 120 questions
Time limit: 2.5 hours
Exam / certification fees: $250 Official sources

Using Our Practice Resources

Work through all 299 available questions
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NC MPJE: Suggested Study Strategy

1Study NCGS Chapter 90 and 21 NCAC 46 for NC-specific pharmacy regulations

2Master DEA controlled substance schedules, forms (222, 106, 41), and requirements

3Know NC CSRS requirements and mandatory checking protocols

4Review Clinical Pharmacist Practitioner authority and collaborative practice agreements

5Understand federal vs. state law conflicts — the more restrictive law prevails

Frequently Asked Questions

What is the NC MPJE passing score?

The North Carolina MPJE requires a scaled score of 75. The exam has 120 questions (100 scored, 20 pretest) over 2.5 hours at Pearson VUE.

What NC laws are tested?

The NC MPJE covers NCGS Chapter 90, Board of Pharmacy rules (21 NCAC 46), CSRS requirements, Clinical Pharmacist Practitioner authority, and state-specific dispensing regulations.

What is the technician ratio in North Carolina?

NC allows a 2:1 technician-to-pharmacist ratio. Technicians must be registered with the Board and work under direct pharmacist supervision.

How many CE hours does NC require?

NC requires 15 hours of continuing pharmacy education per year (annually). CE must be ACPE-accredited.

What is a Clinical Pharmacist Practitioner in NC?

A Clinical Pharmacist Practitioner (CPP) has expanded prescriptive authority under NCGS §90-85.15A through a collaborative practice agreement with a physician, allowing drug therapy management.

Free Practice Questions for NC MPJE

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