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Exam Review

Key Facts: ME MPJE Exam

120

Questions

100 scored + 20 pretest

75

Passing Score

NABP scaled score

2.5h

Exam Time

Pearson VUE

3:1

Tech Ratio

ME max

30h/2yr

CE Required

ME renewal

$250

Exam Fee

NABP 2026

The ME MPJE covers federal pharmacy law (DEA, FDA, CSA, HIPAA) and Maine-specific regulations including PMP mandatory checks, naloxone standing order, collaborative practice agreements, opioid prescribing limits, 30h/2yr CE, and 3:1 technician ratio.

Sample ME MPJE Practice Questions

Try these sample questions to review concepts for the ME MPJE exam. Each question includes a detailed explanation. Start the interactive quiz above for the full 299+ question experience with AI tutoring.

1Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?
A.Schedule I
B.Schedule II
C.Schedule III
D.Schedule IV
Explanation: Schedule I substances have a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision. Examples include heroin, LSD, and MDMA. Pharmacists cannot dispense Schedule I substances under normal practice.
2A DEA Form 222 is required for the transfer of which schedule of controlled substances between registrants?
A.Schedule II only
B.Schedules II and III
C.Schedules III through V
D.All controlled substances
Explanation: DEA Form 222 (or its electronic equivalent under CSOS) is required for the distribution and transfer of Schedule II controlled substances between DEA registrants. Schedules III-V can be transferred using invoices with specific record-keeping requirements.
3Under federal law, what is the maximum number of refills allowed for a Schedule III controlled substance prescription?
A.No refills allowed
B.Up to 3 refills within 6 months
C.Up to 5 refills within 6 months
D.Up to 5 refills within 1 year
Explanation: Federal law allows up to 5 refills for Schedule III-V controlled substance prescriptions within 6 months from the date the prescription was issued. Schedule II prescriptions cannot be refilled.
4The Durham-Humphrey Amendment of 1951 established which key distinction in drug classification?
A.Generic vs. brand-name drugs
B.Prescription (legend) vs. over-the-counter drugs
C.Controlled vs. non-controlled substances
D.Biological vs. chemical drugs
Explanation: The Durham-Humphrey Amendment to the Federal Food, Drug, and Cosmetic Act established the distinction between prescription (legend) drugs and over-the-counter (OTC) drugs, requiring certain drugs to bear the legend 'Caution: Federal law prohibits dispensing without prescription.'
5Under HIPAA, which of the following is considered a permitted disclosure of protected health information (PHI) without patient authorization?
A.Sharing prescription data with a marketing company
B.Disclosing PHI for treatment, payment, or healthcare operations
C.Posting patient medication lists on social media for educational purposes
D.Providing medication history to a patient's employer upon request
Explanation: HIPAA permits disclosure of PHI without patient authorization for treatment, payment, and healthcare operations (TPO). All other disclosures generally require written patient authorization unless specifically exempted by law.
6The Poison Prevention Packaging Act (PPPA) requires child-resistant containers for most prescription drugs. Which of the following is exempt from this requirement?
A.Oral contraceptives dispensed in manufacturer's compliance packaging
B.All Schedule II controlled substances
C.Any medication for patients over age 50
D.Antibiotics in liquid form
Explanation: Oral contraceptives in manufacturer's mnemonic (compliance) packaging are exempt from PPPA child-resistant packaging requirements. Other exemptions include sublingual nitroglycerin, certain corticosteroid inhalers, and situations where the prescriber or patient requests non-child-resistant packaging.
7Under the Combat Methamphetamine Epidemic Act (CMEA), pseudoephedrine sales are limited to what maximum quantity per 30-day period?
A.3.6 grams
B.7.5 grams
C.9 grams
D.15 grams
Explanation: The CMEA limits pseudoephedrine purchases to 9 grams per 30-day period and 3.6 grams per day. Products must be kept behind the counter or in locked cabinets, and purchasers must present identification and sign a logbook.
8Under OBRA '90, pharmacists are required to perform which of the following for Medicaid patients?
A.Free medication delivery
B.Drug utilization review (DUR) and patient counseling
C.Annual physical examinations
D.Genetic testing before dispensing
Explanation: OBRA '90 (Omnibus Budget Reconciliation Act of 1990) requires pharmacists to conduct prospective drug utilization review (DUR) and offer counseling to Medicaid patients on new prescriptions. Most states have extended this requirement to all patients.
9The FDA's Risk Evaluation and Mitigation Strategies (REMS) program may require which of the following?
A.Mandatory genetic testing for all patients
B.Medication guides, communication plans, or elements to assure safe use (ETASU)
C.Automatic substitution with generic equivalents
D.Prior authorization from the DEA before dispensing
Explanation: REMS may include medication guides, communication plans, and Elements to Assure Safe Use (ETASU) such as prescriber certification, patient registries, or restricted distribution systems. iPLEDGE for isotretinoin is a well-known example of a REMS with ETASU.
10Under the Drug Supply Chain Security Act (DSCSA), pharmacies must maintain transaction records for prescription drugs for how long?
A.1 year
B.3 years
C.6 years
D.10 years
Explanation: The DSCSA requires trading partners, including pharmacies, to maintain transaction information (TI), transaction history (TH), and transaction statements (TS) for at least 6 years to ensure drug supply chain integrity and enable tracing of suspect or illegitimate products.

About the ME MPJE Exam

The Maine MPJE tests knowledge of federal pharmacy law and Maine-specific pharmacy regulations under 32 MRSA Chapter 117. Required alongside the NAPLEX for pharmacist licensure in Maine.

Exam sponsor: NABP / ME Board of Pharmacy. The requirements and fees below concern the certification or admission exam, separate from our free practice resources.

Questions

120 questions

Time Limit

2.5 hours

Passing Score

75 (scaled score)

Exam / Certification Fees

$250

Exam sponsor website

Reported exam pass rate: Not publicly reported. Exam sponsor website

Fees, eligibility, and exam policies can change. Confirm them with the exam sponsor before applying or paying.

Our practice resources: topics covered

We aim to reflect publicly available exam outlines and topic information in our study resources. Coverage, format, and difficulty may differ from the actual exam, and we cannot guarantee that every detail is accurate or current. Confirm exam requirements, fees, and policies with the official exam sponsor.

22%

Licensure & Personnel

Pharmacist qualifications, intern/technician requirements, license renewal, disciplinary actions

33%

Pharmacist Practice

Prescription requirements, counseling, controlled substance rules, collaborative practice agreements

24%

Dispensing Requirements

Generic substitution, prescription transfers, DUR, labeling, PDMP checking

21%

Pharmacy Operations

Controlled substance records, compounding standards, pharmacy permits, automated dispensing

Preparing for the ME MPJE Exam

What You Need to Know

  • Passing score: 75 (scaled score)
  • Exam length: 120 questions
  • Time limit: 2.5 hours
  • Exam / certification fees: $250 Official sources

Using Our Practice Resources

  • Work through all 299 available questions
  • Review every answer and explanation
  • Track weak areas and revisit them
  • Use our AI tutor for tough concepts

ME MPJE: Suggested Study Strategy

1Study 32 MRSA Chapter 117 for Maine-specific pharmacy regulations
2Master DEA controlled substance schedules, forms (222, 106, 41), and corresponding responsibilities
3Know Maine PMP requirements and mandatory query triggers
4Review Maine naloxone standing order and collaborative practice agreements
5Understand federal vs. state law conflicts — the more restrictive law prevails

Frequently Asked Questions

What is the ME MPJE passing score?

The Maine MPJE requires a scaled score of 75. The exam has 120 questions (100 scored, 20 pretest) over 2.5 hours at Pearson VUE.

What Maine laws are tested?

The ME MPJE covers 32 MRSA Chapter 117, Board of Pharmacy rules, PMP requirements, collaborative practice, opioid prescribing limits, and state-specific dispensing/controlled substance regulations.

What is the technician ratio in Maine?

Maine allows a 3:1 technician-to-pharmacist ratio. Technicians must be registered with the Board and work under direct pharmacist supervision.

How many CE hours does Maine require?

Maine requires 30h/2yr of continuing pharmacy education per renewal period. CE must be ACPE-accredited.

What are Maine's opioid prescribing limits?

Under 22 MRSA §7253, initial opioid prescriptions for acute pain are limited to a 7-day supply with dose limitations. Exceptions exist for chronic pain, cancer, palliative care, and MAT.