Free TCTCN Exam Prep
Transplantation and Cellular Therapy Certified Nurse
Prepare for the TCTCN exam without spending hundreds on expensive prep courses. Free study guides, practice questions, flashcards, and related exam resources.
Quick Facts
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Pre-Transplant/Cellular Therapy & ConditioningYou are here
Learn patient and donor evaluation, HLA typing, conditioning regimens, disease indications, CAR-T patient selection, and pre-procedure workup protocols (18% of exam).
Transplantation/Cellular Therapy Procedure
Master stem cell collection, processing, infusion procedures, CAR-T cell infusion, engraftment monitoring, and acute complications management (22% of exam).
Post-Procedure Care, GVHD, CRS & ICANS
Study acute and chronic GVHD, cytokine release syndrome (CRS), immune effector cell-associated neurotoxicity syndrome (ICANS), infection prevention, and organ toxicities — the largest domain at 28%.
Survivorship, Professional Practice & Review
Cover late effects, secondary malignancies, quality of life, evidence-based practice, and ethics (32% combined). Take practice exams to solidify knowledge.
Can You Take the TCTCN Exam?
Check if you meet the basic eligibility requirements
- •Minimum 2 years of practice as an RN
- •Minimum 2,000 hours of HCT or cellular therapy nursing within the last 4 years
- •Minimum 10 contact hours of continuing education in HCT or cellular therapy nursing within the last 4 years
- •Current, active, unencumbered RN license in the US, Canada, or US territory
- •Renewal every 4 years with continuing education or re-examination
TCTCN Quick Facts
Time to Get Licensed
8-12 weeks typical
From start to license in hand
Retake Policy
Must wait 90 days between attempts. Maximum of 3 attempts per eligibility period.
Total Cost Breakdown
Free TCTCN Prep Tools
Reported exam pass rate: ~70%. Check the exam sponsor for the latest official figure.
126+ Practice Questions
Practice by topic with detailed answer explanations
AI Tutor Explains Mistakes
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Updated for 2026
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What You'll Study
8 chapters covering the exam topics in this guide
Introduction & Exam Overview
4 sections
Chapter 2: Foundations of Transplantation & Cellular Biology
7 sections
Chapter 3: Product Collection, Processing & Infusion Procedures
8 sections
Chapter 4: Acute Post-HSCT Complications & Graft-versus-Host Disease
8 sections
Chapter 5: Post-Transplant Infections & Supportive Care
5 sections
Chapter 6: Post-Cellular Therapy Management, CRS & ICANS
7 sections
Chapter 7: Chronic GVHD & Long-Term Survivorship
7 sections
Chapter 8: Quality of Life, Ethics & Professional Practice Standards
5 sections
TCTCN Exam Details
Transplantation and Cellular Therapy Certified Nurse
Administered by ONCC
Exam Content Breakdown
Based on the official ONCC content outline
Patient/donor evaluation, HLA typing, conditioning regimens, disease indications, informed consent, and pre-procedure workup for HCT and cellular therapies (including CAR-T)
Stem cell collection and infusion, CAR-T cell infusion, engraftment monitoring, acute infusion reactions, supportive care during aplasia
GVHD management, CRS and ICANS recognition/treatment, infection prevention, organ toxicities, immune reconstitution
Late effects screening, secondary malignancies, chronic GVHD, quality of life, psychosocial support
Evidence-based practice, ethics, patient/family education, standards of care, quality improvement
What's Included
8 Chapters
Complete exam coverage
Practice Quizzes
With detailed explanations
Free to Start
No credit card required
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What's Next After the TCTCN?
After passing the TCTCN, you can pursue these career paths
TCTCN Exam FAQ
Official ONCC Resources
Verify information with these official sources
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