100+ Free CPHON Practice Questions
Pass your Certified Pediatric Hematology Oncology Nurse exam on the first try — instant access, no signup required.
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Key Facts: CPHON Exam
~75%
Pass Rate
ONCC
165
Total Questions
125 scored
3 hrs
Time Limit
ONCC
2,000 hrs
Required Experience
Pediatric hem/onc
$300-$420
Exam Fee
ONCC
4 years
Certification Validity
ONCC
The CPHON (Certified Pediatric Hematology Oncology Nurse) exam is administered by ONCC with an approximate 75% pass rate. It consists of 165 multiple-choice questions (125 scored, 40 pretest) over 3 hours. Treatment modalities is the largest domain at 24%. Candidates must hold an active RN license with 2,000 hours of pediatric hematology/oncology nursing experience. The credential is valid for 4 years and is supported by both ONS and APHON (Association of Pediatric Hematology/Oncology Nurses).
About the CPHON Exam
Specialty certification for registered nurses in pediatric hematology and oncology nursing. The CPHON validates expertise in caring for children with cancer and blood disorders, covering treatment modalities, symptom management, developmental considerations, and family-centered care.
Questions
165 scored questions
Time Limit
3 hours
Passing Score
Pass/Fail (scaled)
Exam Fee
$300 (ONS/APHON member) / $420 (non-member) (ONCC)
CPHON Exam Content Outline
Health Promotion and Disease Prevention
Genetic counseling, screening, immunizations, health maintenance in immunocompromised children
Scientific Basis and Pathophysiology
Cancer biology, hematologic disorders, genetics, staging, diagnostic workup
Treatment Modalities
Chemotherapy, radiation, surgery, immunotherapy, transplant, clinical trials
Symptom Management
Pain, nausea/vomiting, mucositis, infection, bleeding, nutrition, fatigue
Psychosocial and End-of-Life
Developmental considerations, coping, palliative care, bereavement, family support
Professional Practice
Evidence-based practice, ethics, education, quality improvement, advocacy
How to Pass the CPHON Exam
What You Need to Know
- Passing score: Pass/Fail (scaled)
- Exam length: 165 questions
- Time limit: 3 hours
- Exam fee: $300 (ONS/APHON member) / $420 (non-member)
Keys to Passing
- Complete 500+ practice questions
- Score 80%+ consistently before scheduling
- Focus on highest-weighted sections
- Use our AI tutor for tough concepts
CPHON Study Tips from Top Performers
Frequently Asked Questions
What is the CPHON exam pass rate?
The CPHON exam has an approximate 75% pass rate. The exam uses a scaled scoring system where 125 of the 165 questions are scored (40 are unscored pretest items). With dedicated preparation using practice questions and hands-on pediatric oncology experience, most well-prepared candidates pass on their first attempt.
What are the CPHON eligibility requirements?
To sit for the CPHON exam, you need: 1) A current, active, unencumbered RN license. 2) A minimum of 2,000 hours of pediatric hematology/oncology nursing practice within the last 4 years. 3) At least 10 contact hours of continuing education in pediatric hematology/oncology nursing within the last 4 years.
How hard is the CPHON exam?
The CPHON is an advanced specialty certification. Treatment modalities (24% of the exam) is typically the most challenging domain, covering chemotherapy protocols, radiation therapy, immunotherapy, and transplant for pediatric patients. With 60-100 hours of study over 8-12 weeks, experienced pediatric hem/onc nurses are well-prepared.
What content domains are on the CPHON exam?
The CPHON covers 6 domains: Health Promotion and Disease Prevention (14%), Scientific Basis and Pathophysiology (18%), Treatment Modalities (24%), Symptom Management (20%), Psychosocial and End-of-Life (14%), and Professional Practice (10%). Treatment modalities is the largest section covering chemotherapy, radiation, and immunotherapy.
How should I study for the CPHON exam?
Plan for 60-100 hours of study over 8-12 weeks. Focus heavily on treatment modalities (24%) and symptom management (20%). Use the ONCC test content outline as your study framework. Review pediatric-specific drug protocols, age-appropriate dosing, and developmental considerations. Complete at least 100 practice questions and score 80%+ consistently before scheduling.