Free CPHON Exam Prep
Certified Pediatric Hematology Oncology Nurse
Prepare for the CPHON exam without spending hundreds on expensive prep courses. Free study guides, practice questions, flashcards, and related exam resources.
Quick Facts
Explore More ONCC Oncology Nursing Certifications
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Videos and articles for deeper review.
CPHON ONCC Oncology Nursing Certifications License: Complete Roadmap
Follow this path to organize your licensing and exam preparation
Scientific Basis & PathophysiologyYou are here
Learn the biology of childhood cancers, hematologic disorders, genetics, and diagnostic workup that make up 18% of the exam.
Treatment Modalities
Master chemotherapy protocols, radiation therapy, surgical management, immunotherapy, and transplant — the largest section at 24% of the exam.
Symptom Management & Supportive Care
Study pain management, nausea/vomiting, infection prevention, nutrition, and treatment side effects (20% of exam).
Psychosocial, Prevention & Professional Practice
Cover developmental considerations, family-centered care, palliative/end-of-life care, health promotion, ethics, and evidence-based practice (38% combined). Complete practice exams.
Can You Take the CPHON Exam?
Check if you meet the basic eligibility requirements
- •Minimum 2,000 hours of pediatric hematology/oncology nursing practice within the last 4 years
- •Minimum 10 contact hours of continuing education in pediatric hematology/oncology nursing within the last 4 years
- •Current, active, unencumbered RN license in the US or Canada
- •Renewal every 4 years with continuing education or re-examination
CPHON Quick Facts
Time to Get Licensed
8-12 weeks typical
From start to license in hand
Retake Policy
Must wait 90 days between attempts. Maximum of 3 attempts per eligibility period.
Total Cost Breakdown
Free CPHON Prep Tools
Reported exam pass rate: ~75%. Check the exam sponsor for the latest official figure.
148+ Practice Questions
Practice by topic with detailed answer explanations
AI Tutor Explains Mistakes
Understand why answers are wrong, not just which ones
Updated for 2026
Review the latest update date on each resource
$0 Forever
Start without a credit card or trial
What You'll Study
24 chapters covering the exam topics in this guide
Introduction & Exam Overview
3 sections
Care Continuum
4 sections
Leukemias and Lymphomas
3 sections
CNS, Neuroblastoma, and Renal Tumors
3 sections
Sarcomas and Other Solid Tumors
3 sections
Hematologic Disorders
4 sections
Pathophysiology, Genetics, and Diagnostics
3 sections
Clinical Trials and Professional Performance
3 sections
Chemotherapy and Biotherapy
3 sections
Immunotherapy, Cellular Therapy, and Radiation
3 sections
HSCT, Surgery, Transfusion, and Coagulation Therapy
3 sections
Neurologic, Respiratory, and Cardiovascular Effects
3 sections
Gastrointestinal, Renal, Musculoskeletal, and Integumentary Effects
3 sections
Endocrine, Hematologic, Immunologic, and Sensory Effects
3 sections
Pain, Sleep, Fatigue, and Mental Health
3 sections
Supportive Care
4 sections
Infectious and Gastrointestinal Emergencies
3 sections
Metabolic Emergencies
3 sections
DIC, Hyperleukocytosis, and Sinusoidal Obstructive Syndrome
3 sections
Sickle Cell and Hemostasis Emergencies
3 sections
Cardiopulmonary Emergencies
3 sections
Neurologic and Infusion Emergencies
4 sections
Family, Caregivers, and Social Integration
3 sections
Development, Grief, Culture, and Community Resources
3 sections
CPHON Exam Details
Certified Pediatric Hematology Oncology Nurse
Administered by ONCC
Exam Content Breakdown
Based on the official ONCC content outline
Genetic counseling, risk factors, screening, health maintenance, immunizations in immunocompromised children
Biology of cancer, hematologic disorders, genetics, tumor staging, diagnostic workup
Chemotherapy, radiation, surgery, immunotherapy, transplant, clinical trials, safe handling
Pain management, nausea/vomiting, mucositis, infection, bleeding, nutrition, fatigue
Developmental considerations, coping, palliative care, bereavement, family support, survivorship
Evidence-based practice, ethics, patient/family education, quality improvement, advocacy
What's Included
24 Chapters
Complete exam coverage
Practice Quizzes
With detailed explanations
Free to Start
No credit card required

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What's Next After the CPHON?
After passing the CPHON, you can pursue these career paths
OCN
General oncology certified nurse
TCTCN
Blood and marrow transplant certified nurse
CPON
Certified Pediatric Oncology Nurse (advanced practice)
CPHON Exam FAQ
Official ONCC Resources
Verify information with these official sources
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