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AMT Medical Laboratory Scientist
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MLS Quick Facts
Retake Policy
Wait at least 45 days after each failed attempt; maximum four attempts for the MLS certification
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Updated for 2026
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What You'll Study
9 chapters covering everything you need to pass
Chapter 1: General Laboratory Operations, Safety & Quality
6 sections
Chapter 2: Clinical Chemistry & Metabolic Testing
7 sections
Chapter 3: Hematology & Leukocyte Disorders
5 sections
Chapter 4: Coagulation & Hemostasis
3 sections
Chapter 5: Immunology & Serology
2 sections
Chapter 6: Immunohematology & Blood Grouping
4 sections
Chapter 7: Blood Banking & Transfusion Medicine
3 sections
Chapter 8: Clinical Microbiology
5 sections
Chapter 9: Urinalysis & Body Fluids
3 sections
MLS Exam Details
AMT Medical Laboratory Scientist
Administered by AMT
Exam Content Breakdown
Based on the official AMT content outline
Quality systems, laboratory law and regulation, safety, instrumentation, specimen handling, and general operations.
Carbohydrates, proteins, enzymes, electrolytes, acid-base balance, renal, liver, endocrine, toxicology, and therapeutic drug monitoring.
Cell counts and morphology, anemias, leukocyte disorders, hemoglobinopathies, and hematology instrumentation.
Hemostasis pathways, coagulation testing, factor disorders, anticoagulants, and result interpretation.
Immune responses, immunologic methods, infectious serology, autoimmune testing, and result interpretation.
ABO/Rh typing, antibody detection and identification, compatibility testing, and hemolytic disease.
Donor and component selection, component preparation and storage, transfusion practice, and reaction investigation.
Bacteriology, mycology, parasitology, virology, antimicrobial susceptibility, and molecular methods.
Physical, chemical, and microscopic urinalysis plus cerebrospinal, serous, synovial, and other body-fluid analysis.
What's Included
9 Chapters
Complete exam coverage
Practice Quizzes
With detailed explanations
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