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100+ Free PTCB MTM Practice Questions

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Which of the following is one of the five core elements of a Medication Therapy Management (MTM) service as defined by the APhA/NACDS consensus framework?

A
B
C
D
to track
2026 Statistics

Key Facts: PTCB MTM Exam

300/400

Passing Scaled Score

PTCB

65

Multiple-Choice Questions

PTCB

1h 20m

Exam Duration

PTCB

$89

Exam Fee

PTCB 2025/2026

40-80 hrs

Study Time

Recommended

3

Content Domains

PTCB Content Outline

The PTCB MTM Certificate Exam is a 65-question computer-based exam taken in 1 hour 20 minutes. You need a scaled score of 300 (on a 0-400 scale) to pass. The $89 exam is open to active CPhTs who have completed a PTCB-Recognized MTM Education/Training Program. Content covers the five MTM core elements (MTR, PMR, MAP, intervention, documentation), CMS Part D MTM targeting and CMR requirements, PQA adherence measures, 2023 AGS Beers Criteria, and pharmacist/technician workflow in MTM service delivery.

Sample PTCB MTM Practice Questions

Try these sample questions to test your PTCB MTM exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1Which of the following is one of the five core elements of a Medication Therapy Management (MTM) service as defined by the APhA/NACDS consensus framework?
A.Personal Medication Record (PMR)
B.Prior authorization request
C.DUR rejection override
D.Automatic refill enrollment
Explanation: The APhA/NACDS consensus framework defines five core elements of MTM: (1) Medication Therapy Review (MTR), (2) Personal Medication Record (PMR), (3) Medication-related Action Plan (MAP), (4) Intervention and/or referral, and (5) Documentation and follow-up. The PMR is a complete, patient-specific list of prescription and OTC medications.
2Under CMS Medicare Part D rules, how often must a plan sponsor offer a Comprehensive Medication Review (CMR) to each targeted beneficiary enrolled in the MTM program?
A.At least once every 365 days
B.Only upon patient request
C.Every 90 days
D.Once at enrollment only
Explanation: CMS requires Part D plan sponsors to offer an interactive, person-to-person (or telehealth) CMR to each targeted MTM beneficiary at least once every 365 days. The CMR must be performed by a pharmacist or other qualified provider and must result in a written summary for the patient.
3A technician is preparing a Personal Medication Record (PMR) for a patient. Which of the following elements should be included for each medication?
A.Drug name, strength, dose, route, frequency, and indication
B.Drug name and cost only
C.Drug name and prescriber only
D.Drug name, NDC, and manufacturer only
Explanation: A PMR is a comprehensive patient-specific record that should list, for each medication, the name, strength, dose, route, frequency, indication/purpose, prescriber, and start date. The patient uses the PMR to take ownership of their medication list and share it at every healthcare encounter.
4Which CPT code is used to bill an INITIAL face-to-face MTM service provided by a pharmacist to a new patient for the first 15 minutes?
A.99605
B.99606
C.99607
D.99211
Explanation: CPT 99605 is used for MTM service provided by a pharmacist, individual, face-to-face with the patient, initial encounter, up to 15 minutes. CPT 99606 is used for follow-up encounters with an established patient (up to 15 minutes), and CPT 99607 is used as an add-on for each additional 15 minutes beyond the initial code.
5According to PQA medication adherence measures, a patient is considered adherent when the Proportion of Days Covered (PDC) is at least:
A.80%
B.50%
C.70%
D.95%
Explanation: The Pharmacy Quality Alliance (PQA) defines a patient as adherent when PDC is greater than or equal to 80% during the measurement period. PDC is used in CMS Star Ratings for three adherence measures: diabetes medications, hypertension (RAS antagonists), and cholesterol (statins).
6Which three therapeutic classes are included in the CMS Star Ratings PQA adherence measures?
A.Diabetes medications, RAS antagonists (hypertension), and statins
B.Antibiotics, anticoagulants, and opioids
C.Beta-blockers, diuretics, and PPIs
D.Insulin, inhalers, and antidepressants
Explanation: The three PQA-developed adherence measures used in CMS Star Ratings are: adherence to non-insulin diabetes medications, adherence to renin-angiotensin system (RAS) antagonists (ACE inhibitors, ARBs, direct renin inhibitors), and adherence to statins. Each uses a PDC 80% or greater threshold.
7A patient filled a 30-day supply of atorvastatin 4 times during a 180-day measurement window with no overlap. What is the approximate PDC?
A.67%
B.100%
C.50%
D.80%
Explanation: PDC = (days covered in the measurement period) / (days in the measurement period). Four 30-day fills = 120 days covered. 120/180 = 66.7%, or approximately 67%. Since this is below 80%, the patient would not meet the PQA adherence threshold and would be flagged for intervention.
8Which of the following is classified as a potentially inappropriate medication in older adults according to the 2023 AGS Beers Criteria?
A.Diphenhydramine for routine allergy or insomnia use
B.Acetaminophen 500 mg
C.Atorvastatin 40 mg
D.Lisinopril 10 mg
Explanation: The 2023 AGS Beers Criteria recommend avoiding first-generation antihistamines such as diphenhydramine in older adults due to strong anticholinergic effects, risk of confusion, dry mouth, constipation, and increased fall risk. Acetaminophen, atorvastatin, and lisinopril are not on the Beers avoid list.
9According to the 2023 AGS Beers Criteria, which benzodiazepine-related concern is emphasized for older adults?
A.Benzodiazepines should generally be avoided in older adults due to increased risk of cognitive impairment, delirium, falls, and fractures
B.Benzodiazepines are preferred for chronic insomnia in older adults
C.Short-acting benzodiazepines carry no risk in older adults
D.Benzodiazepines should be used first-line for generalized anxiety in older adults
Explanation: The 2023 Beers Criteria recommend avoiding benzodiazepines in older adults (except for specific indications like severe generalized anxiety disorder, seizure disorders, REM sleep behavior disorder, benzodiazepine withdrawal, ethanol withdrawal, and periprocedural anesthesia). Older adults have increased sensitivity and decreased metabolism of benzodiazepines, raising risks of cognitive impairment, delirium, falls, and fractures.
10Which of the following is considered to have STRONG anticholinergic activity per the 2023 AGS Beers Criteria list of drugs to avoid in older adults?
A.Oxybutynin (immediate release)
B.Metformin
C.Amlodipine
D.Levothyroxine
Explanation: Oxybutynin IR is a bladder antispasmodic with strong anticholinergic properties and is included in Table 7 of the 2023 Beers Criteria. It contributes to anticholinergic burden and is associated with confusion, dry mouth, constipation, urinary retention, and cognitive decline in older adults. Mirabegron or topical oxybutynin may be preferred alternatives.

About the PTCB MTM Exam

The PTCB Medication Therapy Management (MTM) Certificate is an assessment-based certificate program for pharmacy technicians who support MTM services. It validates knowledge of Medicare Part D MTM core elements, CMRs/TMRs, the Personal Medication Record, high-risk medications, and documentation.

Questions

65 scored questions

Time Limit

1 hour 20 minutes

Passing Score

300 (scaled, 0-400)

Exam Fee

$89 (PTCB)

PTCB MTM Exam Content Outline

40%

Medications and Medical Concepts

Drug strengths/doses, interchangeable classes, dosage forms, routes, storage, and common medication-related problems (duplications, interactions, adherence, adverse effects)

36%

Patient Safety and Quality Assurance Strategies

Adherence calculations (PDC), Beers Criteria high-risk medications in older adults, prescribing errors, accuracy reviews, and identification of medication-related problems

24%

MTM Administration and Management

MTM program definitions and core elements (MTR, PMR, MAP, intervention, documentation), Medicare Part D CMS requirements (CMR/TMR), service documentation, and billing

How to Pass the PTCB MTM Exam

What You Need to Know

  • Passing score: 300 (scaled, 0-400)
  • Exam length: 65 questions
  • Time limit: 1 hour 20 minutes
  • Exam fee: $89

Keys to Passing

  • Complete 500+ practice questions
  • Score 80%+ consistently before scheduling
  • Focus on highest-weighted sections
  • Use our AI tutor for tough concepts

PTCB MTM Study Tips from Top Performers

1Memorize the five MTM core elements in order: MTR, PMR, MAP, intervention/referral, and documentation/follow-up
2Learn the CMS Part D targeting criteria — multiple chronic diseases, multiple Part D medications, and annual drug cost threshold — and know that CMRs are offered at least annually while TMRs are performed quarterly
3Master the 2023 AGS Beers Criteria high-risk medications in older adults: first-gen antihistamines, benzodiazepines, Z-drugs, glyburide, cyclobenzaprine, metoclopramide, and drugs with strong anticholinergic activity
4Understand PDC calculation and the 80% PQA adherence threshold, along with the three Star Ratings adherence measures (diabetes, RAS antagonists, statins)
5Know the MTM billing codes: 99605 (initial 15 min), 99606 (subsequent 15 min), 99607 (each additional 15 min add-on)
6Practice identifying drug therapy problems using the four categories: indication, effectiveness, safety, and adherence

Frequently Asked Questions

What is the PTCB MTM Certificate Exam?

The PTCB Medication Therapy Management Certificate is an assessment-based certificate program that validates a pharmacy technician's knowledge of MTM services. It is a 65-question computer-based exam (1 hour 20 minutes) offered at Pearson VUE test centers and via online proctoring. A passing scaled score of 300 (on a 0-400 scale) is required.

What are the eligibility requirements for the PTCB MTM Certificate Exam?

Candidates must (1) hold an active PTCB CPhT Certification and (2) complete a PTCB-Recognized Medication Therapy Management Education/Training Program. There is no specific number of years of MTM work experience required, but prior MTM exposure is highly recommended.

How much does the PTCB MTM Certificate Exam cost?

The application fee is $89 (2025/2026) paid directly to PTCB. This does not include the cost of the PTCB-Recognized MTM Education/Training Program, which is paid separately to the training provider and varies by organization.

What score do I need to pass the PTCB MTM Certificate Exam?

A passing scaled score of 300 on a 0-400 scale is required. PTCB uses scaled scoring to account for minor differences in difficulty across exam forms, so passing is not reported as a raw percentage. Focus preparation on the three knowledge domains, especially the 40% Medications and Medical Concepts section.

What content is covered on the PTCB MTM Certificate Exam?

The exam covers three domains: (1) Medications and Medical Concepts (40%), (2) Patient Safety and Quality Assurance Strategies (36%), and (3) MTM Administration and Management (24%). Key topics include the five MTM core elements (MTR, PMR, MAP, intervention, documentation), Medicare Part D CMR/TMR requirements, PQA adherence measures, 2023 Beers Criteria high-risk medications, documentation, and billing codes 99605/99606/99607.

What is a CMR vs. a TMR in Medicare Part D MTM?

A Comprehensive Medication Review (CMR) is an interactive, person-to-person or telehealth review performed at least once every 365 days by a pharmacist or qualified provider and results in a written summary (PMR + MAP) to the patient. A Targeted Medication Review (TMR) addresses specific medication issues (adherence, duplications, high-risk meds) and must be performed quarterly after enrollment.

What is the role of a pharmacy technician in MTM?

Technicians play a critical support role: identifying MTM-eligible patients, scheduling CMRs, gathering medication history (Rx, OTC, herbals, supplements), drafting the Personal Medication Record, documenting interventions, monitoring adherence gaps (PDC), and following up with patients on their action plans. Clinical decisions and the CMR itself must be performed by a pharmacist or other qualified provider.

How should I study for the PTCB MTM Certificate Exam?

Plan for 40-80 hours of study over 4-8 weeks. Focus on the APhA/NACDS MTM core elements framework, CMS Part D MTM rules (CMR/TMR), 2023 AGS Beers Criteria, PQA adherence measures (PDC greater than or equal to 80% for diabetes, RAS antagonists, and statins), CPT codes 99605/99606/99607, and common drug therapy problems. Complete 100+ practice questions and review any topics with explanations.