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300+ Free PTCE Practice Questions

Pass your Pharmacy Technician Certification Exam exam on the first try — instant access, no signup required.

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~70% Pass Rate
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Question 1
Score: 0/0

If a pharmacy discovers a significant theft or loss of controlled substances, it must be reported to the DEA using:

A
B
C
D
to track
2026 Statistics

Key Facts: PTCE Exam

~70%

First-Time Pass Rate

PTCB

1,400

Passing Score

Scaled, out of 1,600

80-100 hrs

Study Time

Recommended

35%

Medications Weight

Largest domain

$129

Exam Fee

PTCB

1h 50m

Time Limit

PTCB

The PTCE has 90 total questions (80 scored + 10 pretest) with a 1 hour 50 minute time limit. A scaled score of 1,400 (out of 1,600) is required to pass. The exam costs $129 and is administered at Pearson VUE centers. The Medications domain (35%) is the largest section. PTCB certification is accepted in all 50 states and recognized by major pharmacy chains.

Sample PTCE Practice Questions

Try these sample questions to test your PTCE exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 300+ question experience with AI tutoring.

1What is the generic name for the brand drug Lipitor?
A.Rosuvastatin
B.Simvastatin
C.Atorvastatin
D.Pravastatin
Explanation: Atorvastatin is the generic name for Lipitor, a widely prescribed HMG-CoA reductase inhibitor (statin) used for hyperlipidemia. Rosuvastatin is Crestor, simvastatin is Zocor, and pravastatin is Pravachol.
2Which brand name corresponds to the generic drug escitalopram?
A.Celexa
B.Lexapro
C.Prozac
D.Zoloft
Explanation: Lexapro is the brand name for escitalopram, an SSRI antidepressant. Celexa is citalopram, Prozac is fluoxetine, and Zoloft is sertraline. Escitalopram is the S-enantiomer of citalopram and is considered more potent at lower doses.
3The generic name for Synthroid is:
A.Liothyronine
B.Levothyroxine
C.Methimazole
D.Propylthiouracil
Explanation: Levothyroxine is the generic name for Synthroid, the most commonly prescribed thyroid replacement hormone (T4). Liothyronine (Cytomel) is T3, methimazole (Tapazole) is an antithyroid agent, and propylthiouracil (PTU) is also an antithyroid agent.
4Which of the following is the brand name for duloxetine?
A.Effexor
B.Pristiq
C.Cymbalta
D.Savella
Explanation: Cymbalta is the brand name for duloxetine, a serotonin-norepinephrine reuptake inhibitor (SNRI) used for depression, generalized anxiety disorder, diabetic neuropathy, and fibromyalgia. Effexor is venlafaxine, Pristiq is desvenlafaxine, and Savella is milnacipran.
5What is the generic name for Eliquis?
A.Rivaroxaban
B.Dabigatran
C.Apixaban
D.Edoxaban
Explanation: Apixaban is the generic name for Eliquis, a direct oral anticoagulant (DOAC) that is a factor Xa inhibitor. Rivaroxaban is Xarelto, dabigatran is Pradaxa (a direct thrombin inhibitor), and edoxaban is Savaysa. Eliquis is one of the top-prescribed medications in the U.S.
6Jardiance is the brand name for which generic medication?
A.Canagliflozin
B.Dapagliflozin
C.Empagliflozin
D.Ertugliflozin
Explanation: Empagliflozin is the generic name for Jardiance, a sodium-glucose co-transporter 2 (SGLT2) inhibitor used for type 2 diabetes and heart failure. Canagliflozin is Invokana, dapagliflozin is Farxiga, and ertugliflozin is Steglatro. The "-gliflozin" suffix identifies the SGLT2 inhibitor drug class.
7Which generic drug corresponds to the brand name Ozempic?
A.Dulaglutide
B.Liraglutide
C.Semaglutide
D.Tirzepatide
Explanation: Semaglutide is the generic name for Ozempic (subcutaneous injection for type 2 diabetes). Semaglutide is also marketed as Wegovy (for weight management) and Rybelsus (oral tablet). Dulaglutide is Trulicity, liraglutide is Victoza/Saxenda, and tirzepatide is Mounjaro/Zepbound.
8The brand name Entresto contains which combination of generic drugs?
A.Amlodipine/benazepril
B.Sacubitril/valsartan
C.Hydrochlorothiazide/losartan
D.Aliskiren/amlodipine
Explanation: Entresto contains sacubitril/valsartan, a combination neprilysin inhibitor and angiotensin II receptor blocker (ARNI) used for heart failure with reduced ejection fraction. It was the first drug in its class approved by the FDA and has shown significant mortality reduction in HFrEF.
9What is the brand name for the combination drug sumatriptan/naproxen sodium?
A.Treximet
B.Imitrex
C.Maxalt
D.Relpax
Explanation: Treximet is the brand name for sumatriptan/naproxen sodium, a combination triptan/NSAID for acute migraine treatment. Imitrex is sumatriptan alone, Maxalt is rizatriptan, and Relpax is eletriptan. The combination provides both serotonin receptor agonism and anti-inflammatory action.
10Which of the following is the correct generic name for the brand drug Brilinta?
A.Clopidogrel
B.Prasugrel
C.Ticagrelor
D.Vorapaxar
Explanation: Ticagrelor is the generic name for Brilinta, a P2Y12 platelet inhibitor used to reduce cardiovascular events in patients with acute coronary syndrome. Unlike clopidogrel (Plavix) and prasugrel (Effient), ticagrelor binds reversibly to the P2Y12 receptor.

About the PTCE Exam

The Pharmacy Technician Certification Exam (PTCE) is administered by the PTCB and qualifies pharmacy technicians to work in retail, hospital, and specialty pharmacy settings. It covers medications, federal requirements, patient safety, and order processing.

Questions

80 scored questions

Time Limit

1 hour 50 minutes

Passing Score

1,400/1,600 scaled

Exam Fee

$129 (PTCB (Pearson VUE))

PTCE Exam Content Outline

35%

Medications

Generic/brand names, drug classes, mechanisms, side effects, interactions

18.75%

Federal Requirements

DEA regulations, controlled substances, FDA recalls, HIPAA

23.75%

Patient Safety & Quality Assurance

Error prevention, high-alert meds, look-alike/sound-alike drugs

22.5%

Order Entry & Processing

Prescription intake, calculations, filling, compounding, billing

How to Pass the PTCE Exam

What You Need to Know

  • Passing score: 1,400/1,600 scaled
  • Exam length: 80 questions
  • Time limit: 1 hour 50 minutes
  • Exam fee: $129

Keys to Passing

  • Complete 500+ practice questions
  • Score 80%+ consistently before scheduling
  • Focus on highest-weighted sections
  • Use our AI tutor for tough concepts

PTCE Study Tips from Top Performers

1Memorize the top 200 drugs — generic name, brand name, drug class, and common side effects
2Master controlled substance schedules I-V and DEA regulations for ordering and dispensing
3Practice pharmacy calculations: dosing, day supply, concentrations, and conversions
4Know look-alike/sound-alike drugs and high-alert medications (ISMP list)
5Understand the difference between non-sterile and sterile compounding (USP 795 vs 797)

Frequently Asked Questions

What is the PTCE pass rate?

The PTCE has an approximate 70% first-time pass rate. The exam has 90 total questions (80 scored, 10 pretest) and requires a scaled score of 1,400 out of 1,600. The Medications domain at 35% is the largest section and often the most challenging.

How many questions are on the PTCE?

The PTCE has 90 total questions: 80 scored and 10 unscored pretest questions. You have 1 hour and 50 minutes to complete the exam. Questions are multiple-choice covering medications, federal requirements, patient safety, and order processing.

How hard is the PTCE?

The PTCE is moderately challenging. The Medications domain (35%) requires memorizing hundreds of generic/brand name pairs, drug classes, and interactions. Most candidates study 80-100 hours over 4-8 weeks. Focus on the top 200 drugs and controlled substance schedules.

What is the difference between PTCE and ExCPT?

Both certify pharmacy technicians, but they are administered by different organizations. PTCE is from PTCB (Pearson VUE) while ExCPT is from NHA (PSI). PTCE is more widely recognized and accepted in all 50 states. PTCE has 90 questions; ExCPT has 120 questions.

How long should I study for the PTCE?

Plan for 80-100 hours of study over 4-8 weeks. Prioritize the Medications domain (35% of exam) — learn the top 200 drugs by generic/brand name. Then master pharmacy calculations (dosing, concentrations, day supply) and controlled substance schedules (I-V).