100+ Free THPT Biology Practice Questions
Pass your Ky thi tot nghiep THPT - mon Sinh hoc (Vietnam High School Graduation Examination - Biology) exam on the first try — instant access, no signup required.
Ở người, sự trao đổi khí O2 và CO2 giữa máu và không khí diễn ra chủ yếu ở cấu trúc nào của phổi?
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Key Facts: THPT Biology Exam
A 50-minute, 10-point Biology elective in Vietnam's high school graduation exam with 28 questions across three formats (4-option MCQ, true/false multi-statement, short answer); ~85% grade-12 genetics, evolution and ecology.
Sample THPT Biology Practice Questions
Try these sample questions to test your THPT Biology exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.
1Trong cấu trúc phân tử ADN xoắn kép của sinh vật, hai mạch polynucleotide liên kết với nhau bằng liên kết nào giữa các base nitơ bổ sung?
2Một đoạn mạch gốc (mạch khuôn) của gen có trình tự 3'-TAC GGA TTA-5'. Trình tự nucleotide của phân tử mARN được phiên mã từ đoạn này là gì?
3Mã di truyền có tính thoái hóa (degeneracy). Đặc điểm này được hiểu là:
4Trong quá trình dịch mã (translation), thành phần nào trực tiếp vận chuyển amino acid đến ribosome và khớp với codon trên mARN theo nguyên tắc bổ sung?
5Theo mô hình điều hòa hoạt động của operon Lac ở vi khuẩn E. coli, khi môi trường KHÔNG có lactose thì điều gì xảy ra?
6Đột biến gen làm thay thế một cặp nucleotide nhưng bộ ba mới vẫn mã hóa cùng một amino acid như trước được gọi là đột biến:
7Một gen bị mất 1 cặp nucleotide ở vị trí thứ 5 trong vùng mã hóa. Hậu quả thường gặp nhất đối với chuỗi polypeptide là gì?
8Trong quá trình nhân đôi ADN, mạch mới được tổng hợp gián đoạn thành các đoạn ngắn (đoạn Okazaki) là do:
9Ở sinh vật nhân thực, bộ nhiễm sắc thể tồn tại thành từng cặp tương đồng. Mỗi cặp NST tương đồng gồm:
10Trong phép lai một cặp tính trạng của Mendel, khi lai hai cơ thể thuần chủng khác nhau về một cặp tính trạng tương phản (AA × aa), kiểu hình ở F1 và tỉ lệ kiểu hình ở F2 lần lượt là:
About the THPT Biology Exam
Biology is an elective subject of Vietnam's High School Graduation Examination (Ky thi tot nghiep THPT) under the 2018 General Education Program. The real Biology paper lasts 50 minutes and contains 28 questions (40 scored statements) in three parts: 18 four-option multiple-choice questions (Part I), 4 true/false items each with 4 sub-statements (Part II), and 6 short-answer questions (Part III), for a total of 10 points. Content draws about 85% from grade 12 (genetics, evolution, ecology), 10% from grade 11 (plant and animal physiology) and 5% from grade 10 (cell and molecular biology), tested at the recall, comprehension and application levels. Following the 2025 reform under Decision 4068/QD-BGDDT, the graduation exam was cut to 4 subjects and Biology became a separate elective rather than part of the combined Natural Sciences test.
Questions
100 scored questions
Time Limit
50 minutes (real exam)
Passing Score
Scored out of 10; no fixed single-subject pass mark. Graduation uses a composite formula (exam scores plus grade-12 GPA), broadly requiring an overall weighted average of at least 5.0 and no subject at or below 1.0.
Exam Fee
Free. The high school graduation exam is state-funded; there is no separate exam fee. (Bo Giao duc va Dao tao (Ministry of Education and Training, MOET), via provincial Departments of Education and Training)
THPT Biology Exam Content Outline
Genetics (di truyen hoc)
Molecular and chromosomal genetics, Mendelian laws, linkage and sex-linked inheritance, mutations, population genetics (Hardy-Weinberg) and genetic technology applications.
Ecology (sinh thai hoc)
Environmental factors, population and community ecology, ecosystems, energy flow, biogeochemical cycles, conservation and sustainable development.
Evolution (tien hoa)
Evidence of evolution, Darwinian theory and modern synthesis, evolutionary factors, speciation, reproductive isolation and the origin of life.
Cell & Molecular Biology (grade 10)
Cell theory, cell types, organelles, membrane transport, enzymes, cellular respiration, mitosis and meiosis.
Organism Physiology (grade 11)
Plant physiology (uptake, transpiration, photosynthesis, transport, responses) and animal physiology (digestion, respiration, circulation, homeostasis, excretion, nervous system).
How to Pass the THPT Biology Exam
What You Need to Know
- Passing score: Scored out of 10; no fixed single-subject pass mark. Graduation uses a composite formula (exam scores plus grade-12 GPA), broadly requiring an overall weighted average of at least 5.0 and no subject at or below 1.0.
- Exam length: 100 questions
- Time limit: 50 minutes (real exam)
- Exam fee: Free. The high school graduation exam is state-funded; there is no separate exam fee.
Keys to Passing
- Complete 500+ practice questions
- Score 80%+ consistently before scheduling
- Focus on highest-weighted sections
- Use our AI tutor for tough concepts
THPT Biology Study Tips from Top Performers
Frequently Asked Questions
How long is the THPT Biology exam and how many questions does it have?
The real Biology paper lasts 50 minutes. It has 28 questions worth 40 scored statements: Part I has 18 four-option multiple-choice questions, Part II has 4 true/false items each with 4 sub-statements, and Part III has 6 short-answer questions, for a total of 10 points.
Is Biology compulsory in Vietnam's high school graduation exam?
No. After the 2025 reform under the 2018 General Education Program, the exam was cut to 4 subjects: Maths and Literature are compulsory and students choose two electives. Biology is one of the elective subjects, no longer bundled in the combined Natural Sciences test.
How is Part II (true/false) scored?
Each Part II question has 4 sub-statements that the candidate marks true or false. Scoring is graduated: 0.1 point for 1 correct sub-statement, 0.25 for 2, 0.5 for 3 and 1.0 point for all 4 correct, which strongly rewards full mastery of each item.
What topics dominate the Biology exam?
About 85% of content is from grade 12 - genetics (molecular, chromosomal, population), evolution and ecology - with roughly 10% from grade 11 physiology and 5% from grade 10 cell and molecular biology. Genetics is the single largest area.
Is there a fee for the THPT Biology exam?
No. The High School Graduation Examination is funded by the state, so there is no separate exam fee. Students register through their school; independent (free) candidates register through their provincial Department of Education and Training.
What pass mark do I need in Biology?
There is no fixed single-subject pass mark. The exam is scored out of 10, and graduation is decided by a composite formula combining graduation-exam scores with the grade-12 GPA, broadly requiring an overall weighted average of at least 5.0 with no subject scoring 1.0 or below.
When is the THPT exam usually held?
The High School Graduation Examination is held nationwide in late June; in 2025 the Biology paper was sat on the morning of 27 June, and the 2026 session is scheduled around the same period of late June.