5.2 Integrated Science: Biology, Chemistry, Physics & Earth Science
Key Takeaways
- Cell biology emphasizes organelle specialization: Mitochondria produce ATP via cellular respiration, Chloroplasts conduct photosynthesis, and Ribosomes synthesize proteins.
- Mendelian genetics yields predictable phenotypic ratios, such as the 3:1 ratio in a monohybrid cross of heterozygous dominant parents (Aa x Aa).
- The periodic table displays predictable periodic trends: Electronegativity and Ionization Energy increase up and to the right, whereas Atomic Radius increases down and to the left.
- Newton's Three Laws of Motion govern classical mechanics: Inertia (1st Law), F = ma (2nd Law), and Action-Reaction (3rd Law).
- Plate tectonics drives geological processes along convergent, divergent, and transform boundaries, while atmospheric dynamics dictate weather patterns in the Troposphere.
Integrated Science: Biology, Chemistry, Physics & Earth Science
The General Science component of the ACET spans four major scientific disciplines. Success requires a firm grasp of core vocabulary, foundational equations, biological structures, chemical reactions, physical laws, and Earth system processes.
1. Biological Sciences
Cell Biology & Organelles
All living organisms are composed of cells—prokaryotes (lacking a membrane-bound nucleus, e.g., bacteria) or eukaryotes (containing membrane-bound organelles, e.g., plants, animals, fungi).
| Organelle | Function | Key Characteristic |
|---|---|---|
| Nucleus | Stores genomic DNA and controls cellular activity | Surrounded by a double-membrane nuclear envelope |
| Mitochondria | Generates cellular energy (ATP) via aerobic respiration | Known as the "powerhouse of the cell"; contains own mtDNA |
| Ribosomes | Site of protein synthesis (translation) | Found free in cytoplasm or bound to Rough ER |
| Endoplasmic Reticulum (ER) | Rough ER: protein folding/transport; Smooth ER: lipid synthesis & detoxification | Interconnected network of tubules and sacs |
| Golgi Apparatus | Modifies, sorts, and packages proteins for secretion | Stacks of flattened sacs (cisternae) |
| Chloroplasts | Converts solar energy into chemical energy (glucose) | Present in plants/algae; contains chlorophyll |
Bioenergetics: Photosynthesis vs. Respiration
- Photosynthesis Equation:
- Cellular Respiration Equation: Respiration occurs in three stages: Glycolysis (cytoplasm, anaerobic, net 2 ATP), Krebs Cycle (mitochondrial matrix, 2 ATP), and Oxidative Phosphorylation / Electron Transport Chain (inner mitochondrial membrane, ~32–34 ATP).
Genetics & Inheritance
Gregor Mendel's Laws of Inheritance:
- Monohybrid Cross ($Aa \times Aa$): Produces a 3:1 phenotypic ratio (Dominant : Recessive) and a 1:2:1 genotypic ratio ($1 AA : 2 Aa : 1 aa$).
- Dihybrid Cross ($AaBb \times AaBb$): Produces a 9:3:3:1 phenotypic ratio.
- Central Dogma: DNA $\xrightarrow{\text{Transcription}}$ RNA $\xrightarrow{\text{Translation}}$ Protein. DNA uses bases A, T, C, G; RNA replaces Thymine with Uracil (U).
2. Chemical Sciences
Atomic Structure & Periodic Trends
- Subatomic Particles: Protons ($p^+$, $+1$ charge, mass $\approx 1\text{ amu}$), Neutrons ($n^0$, neutral, mass $\approx 1\text{ amu}$), Electrons ($e^-$, $-1$ charge, negligible mass).
- Atomic Number ($Z$): Number of protons (defines the element). Mass Number ($A$): Protons $+$ Neutrons.
Periodic Table Trends:
Increase Electronegativity & Ionization Energy --->
+--------------------------------------------------+
| | ^
| | |
| | |
+--------------------------------------------------+
Increase Atomic Radius <--- | Downward Increase v
- Electronegativity: The ability of an atom to attract shared electrons in a bond (Fluorine is the most electronegative element).
- Ionization Energy: Energy required to remove an electron from a gaseous atom.
- Atomic Radius: Distance from nucleus to valence shell; decreases across a period (left to right) and increases down a group.
Bonding & pH Scale
- Ionic Bonding: Transfer of electrons from a metal (cation) to a nonmetal (anion), e.g., $\text{NaCl}$.
- Covalent Bonding: Sharing of electron pairs between nonmetal atoms, e.g., $\text{H}_2\text{O}, \text{CO}_2$.
- pH Scale: Logarithmic scale measuring hydrogen ion concentration: $\text{pH} = -\log[\text{H}^+]$.
- $\text{pH} < 7$: Acidic (higher $[\text{H}^+]$)
- $\text{pH} = 7$: Neutral (pure water at $25^\circ\text{C}$)
- $\text{pH} > 7$: Basic / Alkaline
- Logarithmic Rule: A drop from pH 6 to pH 4 represents a 100-fold ($10^2$) increase in acidity ($[\text{H}^+]$).
3. Physics & Mechanics
Classical Mechanics & Newton's Laws
- First Law (Inertia): An object remains at rest or in uniform motion unless acted upon by a net external force.
- Second Law ($F = ma$): Force equals mass times acceleration ($1\text{ N} = 1\text{ kg}\cdot\text{m/s}^2$).
- Third Law (Action-Reaction): For every action, there is an equal and opposite reaction.
Work, Energy & Electricity
- Work: $W = F \cdot d \cdot \cos\theta$ (measured in Joules, $1\text{ J} = 1\text{ N}\cdot\text{m}$).
- Kinetic Energy: $KE = \frac{1}{2} m v^2$ | Potential Energy: $PE = m g h$.
- Law of Conservation of Energy: Total mechanical energy ($KE + PE$) remains constant in an isolated system without friction.
- Ohm's Law: $V = I R$, where $V$ is Voltage (Volts), $I$ is Current (Amperes), and $R$ is Resistance (Ohms $\Omega$).
4. Earth & Atmospheric Science
Earth Structure & Plate Tectonics
Earth is divided into Crust, Mantle, Outer Core (liquid iron-nickel driving the magnetic field), and Inner Core (solid iron-nickel).
- Convergent Boundaries: Plates collide (subduction zones form deep trenches, volcanic arcs, and mountain ranges like the Himalayas).
- Divergent Boundaries: Plates separate (mid-ocean ridges, rift valleys).
- Transform Boundaries: Plates slide past each other horizontally (cause shallow earthquakes along fault lines like the Marikina Valley Fault System).
Atmospheric Layers & Weather Events
- Troposphere: Lowest layer containing 75% of atmospheric mass; all weather phenomena occur here.
- Stratosphere: Contains the Ozone Layer ($\text{O}_3$), which absorbs harmful ultraviolet (UV-B and UV-C) solar radiation.
- El Niño vs. La Niña: El Niño is the anomalous warming of sea surface temperatures in the central/eastern tropical Pacific, causing prolonged droughts in the Philippines. La Niña involves anomalous cooling, bringing heavy rainfall and flooding.
During cellular respiration, in which specific location of a eukaryotic cell does oxidative phosphorylation via the electron transport chain take place to yield the majority of ATP molecules?
If a solution's pH changes from 8.0 to 5.0, by what factor has the hydrogen ion concentration [H+] increased?
According to Newton's Second Law of Motion, what net force is required to accelerate a 1,200 kg vehicle at a rate of 3.0 m/s²?