12.9 Mental, Neurodevelopmental, Behavioral, and Substance Use Conditions

Key Takeaways

  • Major depression requires at least five of nine symptoms, including depressed mood or loss of interest, for at least two weeks; mania lasts at least a week, hypomania at least four days.

  • PTSD symptoms last more than a month after a trauma and include intrusive memories, avoidance, negative mood changes, and hyperarousal.

  • Alcohol and benzodiazepine withdrawal can cause seizures and delirium and need medical supervision; opioid overdose causes pinpoint pupils and slowed breathing and is reversed with naloxone.

  • Bulimia can cause low potassium and dangerous heart rhythms; anorexia has one of the highest death rates of any mental illness.

  • Ask directly about suicidal thoughts; a patient with a plan or intent should not be left alone, and 988 is the national Suicide and Crisis Lifeline.

Last updated: October 2026

12.9 Mental, Neurodevelopmental, Behavioral, and Substance Use Conditions

Quick Answer: Acupuncturists see many patients with anxiety, depression, insomnia, and addiction. The BIOM exam expects you to recognize the main DSM-5 conditions, use simple screening tools, understand withdrawal and overdose dangers, and respond correctly to suicidal ideation. Acupuncture can support mental health care, but it does not replace psychiatric assessment, psychotherapy, or medication. Never advise a patient to stop psychiatric medication; changes must go through the prescriber.

Mood Disorders

ConditionKey features
Major depressive disorderAt least 5 of 9 symptoms for 2 weeks or more, including depressed mood or loss of interest (anhedonia); others are sleep change, appetite or weight change, low energy, guilt or worthlessness, poor concentration, slowed or agitated movement, and thoughts of death
Bipolar I disorderAt least one manic episode lasting a week or more (or requiring hospitalization): elevated or irritable mood, little need for sleep, racing thoughts, grandiosity, risky behavior
Bipolar II disorderHypomanic episodes of at least 4 days plus major depressive episodes
Persistent depressive disorderMilder depressed mood on most days for at least 2 years

Screen with the PHQ-2 (two questions about mood and interest) and the PHQ-9.

Anxiety, OCD, and Trauma-Related Disorders

  • Generalized anxiety disorder: excessive, hard-to-control worry on most days for at least 6 months, with restlessness, fatigue, poor concentration, irritability, muscle tension, and poor sleep. Screen with the GAD-7.
  • Panic disorder: recurrent, unexpected panic attacks that peak within minutes (pounding heart, chest pain, shortness of breath, fear of dying). First-time chest pain must be evaluated medically because panic attacks can mimic a heart attack.
  • Obsessive-compulsive disorder (OCD): intrusive, unwanted thoughts (obsessions) and repetitive behaviors or mental acts (compulsions) that take more than an hour a day or cause distress.
  • Post-traumatic stress disorder (PTSD): after exposure to a traumatic event, symptoms lasting more than one month in four clusters: intrusion (flashbacks, nightmares), avoidance, negative changes in thinking and mood, and changes in arousal (hypervigilance, startle, poor sleep). Use trauma-informed care (Section 10.6).

Psychotic Disorders

Schizophrenia involves delusions, hallucinations, disorganized speech or behavior, and negative symptoms (flat affect, withdrawal) with continuous signs for at least 6 months. New psychotic symptoms, or a patient who stops antipsychotic medication and becomes agitated or confused, needs prompt psychiatric referral.

Neurodevelopmental Conditions

  • ADHD: inattention, hyperactivity, or impulsivity, with several symptoms present before age 12, in two or more settings (home, school, work). Stimulant medications are covered in Section 15.2.
  • Autism spectrum disorder: differences in social communication plus restricted, repetitive behaviors or interests, present from early childhood. Many autistic patients are sensitive to touch, light, and sound. Use a quiet room, predictable routines, clear explanations, and non-insertive methods if needles are not tolerated.

Eating Disorders

ConditionKey featuresMedical risks
Anorexia nervosaRestricted intake, low body weight, intense fear of weight gain, distorted body imageSlow heart rate, low blood pressure, missed periods, osteoporosis, fine body hair (lanugo); one of the highest death rates of any mental illness
Bulimia nervosaBinge eating with compensatory behavior (vomiting, laxatives, fasting, exercise) at least weekly for 3 months; weight often normalLow potassium and heart rhythm problems, calluses on the knuckles (Russell's sign), swollen salivary glands, dental erosion
Binge-eating disorderRecurrent binges without compensatory behaviorObesity, diabetes, depression

Substance Use Disorders

DSM-5 rates severity by the number of 11 criteria met: 2-3 mild, 4-5 moderate, 6 or more severe. Screening tools include the AUDIT-C and the CAGE questions (felt you should Cut down, been Annoyed by criticism, felt Guilty, needed an Eye-opener; two or more "yes" answers suggest a problem).

SubstanceWithdrawalOverdose and emergencies
AlcoholTremor, sweating, anxiety, and nausea from about 6-24 hours; seizures usually within 48 hours; delirium tremens (confusion, hallucinations, fever, high pulse) around days 2-4, which can be fatalMedical detoxification is needed for heavy daily drinkers
BenzodiazepinesAnxiety, insomnia, seizures; never stop abruptlyDangerous breathing depression when combined with opioids or alcohol
OpioidsYawning, sweating, runny nose, dilated pupils, diarrhea, gooseflesh, cravings; very unpleasant but rarely life-threateningOverdose triad: pinpoint pupils, slow or stopped breathing, unresponsiveness. Call 911 and give naloxone, which is now available over the counter as a nasal spray
NicotineIrritability, anxiety, poor concentration, increased appetite, cravings, worst in the first few daysSmoking cessation medications are covered in Section 15.2

The NADA ear protocol (Section 10.2) is widely used to support recovery, alongside medical and behavioral treatment.

Suicidal Ideation

  • Ask directly: "Are you thinking about killing yourself?" Asking does not plant the idea and often brings relief.
  • Assess plan, intent, means, and timing, and protective factors.
  • Imminent risk (a plan, intent, or access to means): do not leave the patient alone, remove access to means if safe, and call 911 or arrange emergency evaluation.
  • No imminent risk: provide the 988 Suicide and Crisis Lifeline (call or text 988), arrange prompt mental health follow-up with the patient's consent, and document the assessment.
  • Confidentiality does not prevent you from acting to protect a patient at serious risk; see Section 16.1 for duty-to-warn rules.
Test Your Knowledge

A patient describes four days of very little sleep without feeling tired, racing thoughts, rapid speech, and unusual spending, followed months earlier by weeks of depression. Which diagnosis do these episodes most suggest?

A

Generalized anxiety disorder

B

Bipolar II disorder

C

Persistent depressive disorder

D

Obsessive-compulsive disorder

Test Your Knowledge

A patient who drinks heavily every day says he will stop drinking completely starting tonight, without medical help. What is the main safety concern?

A

Withdrawal can cause seizures and delirium tremens, so refer him for supervised withdrawal

B

Alcohol withdrawal is always mild and harmless, so he can safely stop on his own tonight

C

Stopping alcohol suddenly causes pinpoint pupils and slowed breathing within hours

D

He should replace the alcohol with benzodiazepines bought online to ease the withdrawal symptoms

Test Your Knowledge

A friend brings a patient into the clinic who is unresponsive, breathing very slowly, and has pinpoint pupils. What is the most likely cause, and what is the immediate response?

A

Hypoglycemia; give orange juice by mouth and recheck in 15 minutes

B

Opioid overdose; call 911, give naloxone, and support breathing

C

Panic attack; coach slow breathing into a paper bag

D

Alcohol withdrawal; give fluids and keep the patient warm

Test Your Knowledge

During a visit, a patient says, "Sometimes I think everyone would be better off without me." What should the practitioner do first?

A

Ask directly about suicidal thoughts, plus any plan, intent, and access to means

B

Change the subject gently to avoid putting the idea of suicide in the patient's mind

C

Add Shen-calming points such as HT 7 and Yintang, then end the visit as planned

D

Reassure the patient that everyone feels this way at times and it will soon pass

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