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Free APMLE Part I Exam Prep

American Podiatric Medical Licensing Examination Part I (Basic Sciences)

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Updated January 2026
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What You'll Study

18 chapters covering the exam topics in this guide

APMLE Part I Exam Details

American Podiatric Medical Licensing Examination Part I (Basic Sciences)

Administered by National Board of Podiatric Medical Examiners (NBPME)

Official Source
75 scaled score (set by NBPME)
Passing Score
205
Questions
4
Hours
$925 per attempt
Exam Fee
Study time: NBPME does not publish official prep hours; most students report 200-400 hours over 8-12 weeks
Prerequisites: Confirmed by dean of an accredited podiatric medical school as a currently enrolled second-year student or having attained equivalent training
Valid for: Lifetime once passed (must be passed before sitting Part II)

Exam Content Breakdown

Based on the official National Board of Podiatric Medical Examiners (NBPME) content outline

Lower Extremity Anatomy25%

Foot and ankle osteology, arthrology, myology, vasculature, peripheral nerves, fascia, dermatomes, surface anatomy, and embryologic development of the lower limb

Microbiology and Immunology14%

Bacteria, viruses, fungi, parasites; sterilization/disinfection; innate and adaptive immunity; hypersensitivity reactions; podiatric-relevant infections (cellulitis, osteomyelitis, onychomycosis)

Pathology14%

Cellular injury, inflammation, neoplasia, hemodynamic disorders; systemic, musculoskeletal, vascular, neurologic, and dermatologic pathology with emphasis on the lower extremity

Pharmacology14%

Pharmacokinetics, pharmacodynamics, autonomic agents, antimicrobials, analgesics, anesthetics, anti-inflammatories, cardiovascular and endocrine drugs commonly used in podiatric practice

General Anatomy12%

Gross anatomy of head, neck, thorax, abdomen, pelvis, upper limb, plus embryology, histology, genetics, and geriatric considerations

Physiology12%

Cell, neuromuscular, cardiovascular, respiratory, renal, endocrine, gastrointestinal, and reproductive physiology relevant to systemic disease and lower extremity function

Biochemistry9%

Amino acids, proteins, enzymes, carbohydrate, lipid, and nucleic acid metabolism; vitamins, hormones, molecular biology, and metabolic disorders

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What's Next After the APMLE Part I?

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APMLE Part I Exam FAQ

Official National Board of Podiatric Medical Examiners (NBPME) Resources

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