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Free Practice Questions for UNA Medicine Admission

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Key Facts: UNA Medicine Admission Exam

240

Multiple-choice questions on the FCM-UNA Medicine entrance exam, in four 60-question subject papers

FCM-UNA admission regulation (Res. CD 915/2025)

190

Medicine places filled in 2026: 150 at the Sede Central and 40 at the Filial Santa Rosa del Aguaray

FCM-UNA official announcement, February 2026

Gs. 750.000

Examination fee, with exemption available to eligible applicants under the Ley 6628/2020 de Arancel Cero

FCM-UNA Dirección de Admisión

4

Subject papers: Biología, Química, Lenguaje y Comunicación, and Ciencias Exactas

FCM-UNA Dirección de Admisión

450 minutes

Total testing time across the four papers in the February 2026 sitting

FCM-UNA admission announcement, February 2026

FCM-UNA's Medicine entrance exam has 240 multiple-choice questions in four 60-question papers (Biology, Chemistry, Language and Communication, Exact Sciences); in 2026 the top scorers filled 190 places.

Sample UNA Medicine Admission Practice Questions

Try these sample questions to review concepts for the UNA Medicine Admission exam. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1Which mitochondrial structural feature provides the extensive surface area required for housing electron transport chain enzyme complexes and ATP synthase during oxidative phosphorylation?
A.The porin channels of the outer mitochondrial membrane
B.The intermembrane space between the two membranes
C.The mitochondrial DNA nucleoids in the matrix
D.The cristae folds of the inner mitochondrial membrane
Explanation: The inner mitochondrial membrane is extensively folded into cristae, dramatically increasing its surface area to accommodate high densities of respiratory chain complexes (Complexes I-IV) and ATP synthase. This structural specialization enables efficient oxidative phosphorylation and high rates of cellular ATP production.
2What is the exact ion stoichiometry and transport mechanism executed by the primary active Na+/K+-ATPase pump during each catalytic cycle?
A.Transports 3 Na+ out of the cell and 2 K+ into the cell per ATP molecule hydrolyzed
B.Transports 2 Na+ into the cell and 3 K+ out of the cell per ATP molecule hydrolyzed
C.Transports 3 Na+ into the cell and 2 K+ out of the cell per GTP molecule hydrolyzed
D.Transports 1 Na+ out of the cell and 1 K+ into the cell via facilitated diffusion
Explanation: The Na+/K+-ATPase is a primary active transport P-type ATPase that hydrolyzes one molecule of ATP to export three sodium ions (Na+) and import two potassium ions (K+) against their respective electrochemical gradients. This electrogenic stoichiometry produces a net loss of one positive charge per cycle, contributing to the negative resting membrane potential.
3In human glycogen architecture, which chemical bonds join the glucose residues in linear chains and at branch points, respectively?
A.alpha-1,4-glycosidic bonds in linear chains and alpha-1,6-glycosidic bonds at branch points
B.beta-1,4-glycosidic bonds in linear chains and alpha-1,4-glycosidic bonds at branch points
C.alpha-1,6-glycosidic bonds in linear chains and beta-1,4-glycosidic bonds at branch points
D.alpha-1,3-glycosidic bonds in linear chains and alpha-1,6-glycosidic bonds at branch points
Explanation: Glycogen is a highly branched homopolymer of alpha-D-glucose. The linear polymeric backbone is linked by alpha-1,4-glycosidic bonds, while branches occur approximately every 8 to 12 glucose residues via alpha-1,6-glycosidic bonds, providing multiple non-reducing ends for rapid enzymatic synthesis and glycogenolysis.
4During which specific sub-stage of meiotic prophase I does genetic crossing over (homologous recombination) occur between non-sister chromatids?
A.Leptotene
B.Zygotene
C.Pachytene
D.Diplotene
Explanation: Crossing over and reciprocal genetic exchange take place during the pachytene sub-stage of prophase I, once the synaptonemal complex is fully assembled between paired homologous chromosomes (bivalents/tetrads). In the subsequent diplotene stage, the synaptonemal complex dissolves, revealing the physical sites of crossing over as chiasmata.
5An individual heterozygous for two independently assorting autosomal genes (genotype AaBb) is testcrossed with a homozygous recessive partner (aabb). What is the expected phenotypic ratio among the offspring?
A.3 : 1
B.9 : 3 : 3 : 1
C.1 : 2 : 1
D.1 : 1 : 1 : 1
Explanation: A testcross crosses an individual of unknown or heterozygous genotype with a homozygous recessive tester (aabb). The heterozygous parent (AaBb) produces four gamete types in equal frequencies: 25% AB, 25% Ab, 25% aB, and 25% ab. The tester contributes only 'ab' gametes, resulting in offspring genotypes AaBb, Aabb, aaBb, and aabb in a 1:1:1:1 phenotypic and genotypic ratio.
6During eukaryotic DNA replication, how are Okazaki fragments on the lagging strand synthesized and subsequently joined?
A.Synthesized in the 3' to 5' direction by RNA primase and joined by topoisomerase II
B.Synthesized continuously in the 5' to 3' direction by DNA helicase and sealed by single-strand binding proteins
C.Synthesized in the 3' to 5' direction by telomerase and joined by DNA polymerase I
D.Synthesized discontinuously in the 5' to 3' direction by DNA polymerase and joined covalently by DNA ligase
Explanation: Because DNA polymerases can only synthesize DNA in the 5' to 3' direction by adding nucleotides to a 3'-OH group, the lagging strand is synthesized discontinuously as short Okazaki fragments. Each fragment begins with an RNA primer, is extended 5' to 3' by DNA polymerase, has its primer excised and replaced with DNA, and is finally joined by DNA ligase via phosphodiester bond formation.
7What is the correct anatomical sequence of the cardiac electrical conduction pathway in the human heart under normal sinus rhythm?
A.Sinoatrial (SA) node -> Atrioventricular (AV) node -> Bundle of His -> Purkinje fibers
B.Atrioventricular (AV) node -> Sinoatrial (SA) node -> Purkinje fibers -> Bundle of His
C.Purkinje fibers -> Bundle of His -> Atrioventricular (AV) node -> Sinoatrial (SA) node
D.Sinoatrial (SA) node -> Purkinje fibers -> Atrioventricular (AV) node -> Bundle of His
Explanation: Cardiac excitation originates in the primary physiological pacemaker, the sinoatrial (SA) node in the right atrium. The impulse propagates through internodal atrial pathways to the atrioventricular (AV) node (where conduction is delayed to allow ventricular filling), travels down the common atrioventricular Bundle of His and bundle branches, and spreads rapidly through the ventricular myocardium via the Purkinje fiber network.
8Which physiological mechanism enables the loop of Henle in juxtamedullary nephrons to generate a hypertonic medullary osmotic gradient?
A.The descending limb actively pumps NaCl out, while the thick ascending limb is freely permeable to water
B.Water leaves the descending limb, while the thick ascending limb pumps out NaCl but stays impermeable to water
C.Both limbs are equally permeable to water and sodium, relying on hydrostatic pressure from the glomerular capillaries
D.The collecting duct actively pumps urea into the interstitium while blocking all sodium reabsorption
Explanation: The countercurrent multiplier system relies on asymmetric permeability between the two limbs of the loop of Henle. The thin descending limb is permeable to water (via aquaporins) and impermeable to solutes, concentrating luminal fluid. The thick ascending limb actively transports Na+, K+, and 2 Cl- (NKCC2 cotransporter) into the medullary interstitium while remaining impermeable to water, creating the osmotic gradient essential for water reabsorption under ADH stimulation.
9Which combination of physiological factors shifts the oxygen-hemoglobin dissociation curve to the right (including the Bohr effect of CO2 and H+), thereby facilitating oxygen unloading in actively metabolizing peripheral tissues?
A.Decreased pCO2, increased pH, and decreased temperature
B.Increased pH, decreased 2,3-bisphosphoglycerate (2,3-BPG), and hypothermia
C.Carbon monoxide poisoning and fetal hemoglobin (HbF) predominance
D.Increased pCO2, decreased pH (increased [H+]), and increased temperature
Explanation: Active skeletal muscle and metabolizing tissues produce carbon dioxide, hydrogen ions (lactic and carbonic acids), and metabolic heat. Elevated pCO2, acidosis (decreased pH), elevated temperature, and increased 2,3-BPG all stabilize hemoglobin in the low-affinity T (taut) state, shifting the dissociation curve to the right and promoting oxygen release to tissues.
10In the renin-angiotensin-aldosterone system (RAAS), what specific enzymatic and hormonal cascade is triggered by decreased renal perfusion pressure detected at the juxtaglomerular apparatus?
A.Renin cleaves angiotensinogen to angiotensin I; ACE converts angiotensin I to angiotensin II, which stimulates aldosterone secretion
B.Aldosterone cleaves angiotensin I directly into renin; angiotensin II then triggers renal potassium retention and sodium loss
C.ACE hydrolyzes angiotensinogen directly to aldosterone; renin then acts on the collecting duct to stimulate renal water loss
D.Renin converts angiotensin II into atrial natriuretic peptide (ANP), which suppresses systemic vasoconstriction
Explanation: Renal hypoperfusion prompts juxtaglomerular cells to secrete the aspartyl protease renin. Renin cleaves hepatic angiotensinogen into decapeptide angiotensin I. Angiotensin-converting enzyme (ACE), predominantly in pulmonary and vascular endothelium, hydrolyzes angiotensin I to octapeptide angiotensin II. Angiotensin II triggers potent arteriolar vasoconstriction and stimulates the adrenal cortex (zona glomerulosa) to secrete aldosterone, promoting renal Na+ reabsorption and K+ excretion.

About the UNA Medicine Admission Exam

Independent FCM-UNA Medicine admission practice by OpenExamPrep. The Examen de Ingreso a la Carrera de Medicina is the competitive entrance examination of the Facultad de Ciencias Médicas of the Universidad Nacional de Asunción (FCM-UNA). Since the 2026 intake the faculty no longer runs its CPAM preparatory course: applicants register directly for four multiple-choice papers in Biología, Química, Lenguaje y Comunicación, and Ciencias Exactas (Física y Matemática), 240 questions in total, and places are awarded by score ranking. The official exam is written and answered in Spanish. This bank is an English-language MCQ study adaptation, not an official translation or a simulation of the exam: Spanish grammar, spelling, and reading items keep their Spanish text, with stems and explanations in English.

Exam sponsor: Facultad de Ciencias Médicas de la Universidad Nacional de Asunción (FCM-UNA). The requirements and fees below concern the certification or admission exam, separate from our free practice resources.

Assessment

240 multiple-choice questions in four 60-question subject papers, each sat on a separate date: Biología, Química, Lenguaje y Comunicación, and Ciencias Exactas (30 Matemática and 30 Física). For admission 2027 the papers are scheduled for 5, 8, 10 and 12 February 2027.

Time Limit

90 minutes for Biología and 120 minutes each for the other three papers in the 2026 sitting (450 minutes in total)

Passing Score

Competitive ranking by total score: places go to the highest-scoring applicants until the seats set for each campus are filled (2026: 150 seats at the Sede Central and 40 at the Filial Santa Rosa del Aguaray)

Exam / Certification Fees

Gs. 750.000

Exam sponsor website

Fees, eligibility, and exam policies can change. Confirm them with the exam sponsor before applying or paying.

Official sources

Our practice resources: topics covered

We aim to reflect publicly available exam outlines and topic information in our study resources. Coverage, format, and difficulty may differ from the actual exam, and we cannot guarantee that every detail is accurate or current. Confirm exam requirements, fees, and policies with the official exam sponsor.

25%

Biología

60 questions: cell biology, biomolecules, genetics, molecular biology, human physiology and organ systems, histology, microbiology and immunology, and ecology

25%

Química

60 questions: atomic structure, periodic properties, chemical bonding, stoichiometry, solutions, chemical equilibrium, acids and bases, thermochemistry, electrochemistry, and organic chemistry

25%

Lenguaje y Comunicación

60 questions: Spanish grammar and morphology, syntax, orthography and accentuation, vocabulary and semantics, reading comprehension, and text cohesion

25%

Ciencias Exactas (Física y Matemática)

60 questions: 30 in mathematics (algebra, functions, geometry, trigonometry, sequences, probability) and 30 in physics (mechanics, energy, fluids, heat, electricity, optics, waves)

Preparing for the UNA Medicine Admission Exam

What You Need to Know

  • Passing score: Competitive ranking by total score: places go to the highest-scoring applicants until the seats set for each campus are filled (2026: 150 seats at the Sede Central and 40 at the Filial Santa Rosa del Aguaray)
  • Assessment: 240 multiple-choice questions in four 60-question subject papers, each sat on a separate date: Biología, Química, Lenguaje y Comunicación, and Ciencias Exactas (30 Matemática and 30 Física). For admission 2027 the papers are scheduled for 5, 8, 10 and 12 February 2027.
  • Time limit: 90 minutes for Biología and 120 minutes each for the other three papers in the 2026 sitting (450 minutes in total)
  • Exam / certification fees: Gs. 750.000 Official sources

Using Our Practice Resources

  • Work through all 100 available questions
  • Review every answer and explanation
  • Track weak areas and revisit them
  • Use our AI tutor for tough concepts

UNA Medicine Admission: Suggested Study Strategy

1Download the official FCM-UNA exam programme from the admission page and use it as your checklist for all four papers.
2Practice multi-step calculations by hand for stoichiometry, solution concentrations, and physics problems, ensuring precision under time pressure.
3Give Spanish morphosyntax, accentuation, and reading comprehension the same study time as the sciences, because Lenguaje y Comunicación is a full 60-question paper.
4Review human physiology and organ systems thoroughly, focusing on cell transport, endocrine regulation, and cardiovascular mechanics.
5Simulate timed 60-question blocks to build stamina and pacing for the 90-minute and 120-minute official exam sessions.

Frequently Asked Questions

What is the FCM-UNA Medicine admission examination?

It is the competitive entrance examination for the Medicine degree (title awarded: Médico/a) at the Facultad de Ciencias Médicas of the Universidad Nacional de Asunción (UNA), held at the Sede Central in Asunción and at the Filial Santa Rosa del Aguaray.

How did the FCM-UNA admission process change in 2026?

From the 2026 intake the faculty stopped offering its Curso Preparatorio de Admisión a Medicina (CPAM). Applicants now study on their own from the official exam programme and register directly for the four subject papers.

How many questions are on the real FCM-UNA exam and how is it scored?

The examination has 240 multiple-choice questions in four 60-question papers: Biología, Química, Lenguaje y Comunicación, and Ciencias Exactas (30 Matemática and 30 Física). Places are awarded by score ranking; in 2026 there were 150 places at the Sede Central and 40 at the Filial Santa Rosa del Aguaray.

What is the examination fee for FCM-UNA Medicine?

The fee is Gs. 750.000. Under Ley 6628/2020 (Arancel Cero), graduates of public or subsidized schools, and graduates of private schools with a Ministerio de Desarrollo Social vulnerability certificate, can request exemption if they meet the faculty's conditions, including finishing secondary school after 1 October 2023 and applying for the first or second time.

What language is the official exam in, and why is this bank in English?

The official exam is in Spanish. OpenExamPrep publishes this bank as an English-language MCQ study adaptation for learners who prepare in English; it is not an official translation or a simulation of the exam. Questions on Spanish grammar, spelling, and reading keep the Spanish text being tested, with English explanations.

How long is each examination paper?

In the 2026 sitting, Biología lasted 90 minutes and Química, Lenguaje y Comunicación, and Ciencias Exactas lasted 120 minutes each, for 450 minutes in total across four separate exam dates.