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Key Facts: Philippines PLE Exam
12
Official PLE Subjects
Medical Act of 1959 and PRC March 2026 Program
4 days
March 2026 PRC Program Length
PRC March 2026 Physicians Licensure Examination Program
75%
General Average Passing Rule
Republic Act No. 2382
70.3%
March 2026 Pass Rate
PRC March 2026 PLE Results
PHP 900
PRC Examination Fee
PRC Standard Baccalaureate Fee Schedule
Prepare for the PLE as a broad, integrated medical licensure exam: six basic-science and therapeutic subjects, five major clinical/public-health subjects, and legal medicine/ethics. The pass rule is a 75% general average with no grade below 50% in any subject (Section 21 of the Medical Act as amended by Republic Act No. 4224). The standard PRC baccalaureate examination fee is PHP 900, with an additional PHP 1,050 initial registration fee upon passing.
Sample Philippines PLE Practice Questions
Try these sample questions to review concepts for the Philippines PLE exam. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.
1A man has a deep laceration at the fibular neck after a motorcycle crash. On examination, he cannot dorsiflex the foot and has sensory loss over the dorsum of the foot. Which nerve is most likely injured?
A.Common fibular nerve
B.Tibial nerve
C.Femoral nerve
D.Obturator nerve
Explanation: The common fibular nerve winds around the fibular neck and is vulnerable to trauma at that site. Injury causes foot drop from loss of anterior compartment dorsiflexors and sensory loss over the dorsum of the foot.
2After thyroid surgery, a patient develops persistent hoarseness and difficulty abducting the vocal cord on laryngoscopy. Which structure was most likely injured?
A.External branch of the superior laryngeal nerve
B.Recurrent laryngeal nerve
C.Hypoglossal nerve
D.Glossopharyngeal nerve
Explanation: The recurrent laryngeal nerve supplies nearly all intrinsic muscles of the larynx, including the posterior cricoarytenoid muscle that abducts the vocal cord. Injury during thyroidectomy classically causes hoarseness and impaired vocal cord movement.
3A biopsy of normal skin from the palm shows a thick epidermis designed to resist abrasion. What type of epithelium lines this surface?
A.Simple cuboidal epithelium
B.Pseudostratified ciliated columnar epithelium
C.Keratinized stratified squamous epithelium
D.Transitional epithelium
Explanation: The epidermis is keratinized stratified squamous epithelium. Multiple cell layers resist mechanical trauma, and the keratin layer is especially thick in palms and soles.
4A man with cirrhosis develops massive hematemesis from esophageal varices. The varices form at an anastomosis between the left gastric vein and which systemic vein?
A.Azygos vein
B.Inferior vena cava
C.Splenic vein
D.Superior mesenteric vein
Explanation: Esophageal varices form where portal venous flow through the left gastric vein communicates with systemic esophageal veins draining to the azygos system. Portal hypertension dilates this collateral pathway and makes it prone to life-threatening bleeding.
5A groin bulge passes medial to the inferior epigastric vessels through Hesselbach triangle. Which diagnosis best fits this anatomy?
A.Femoral hernia
B.Indirect inguinal hernia
C.Direct inguinal hernia
D.Obturator hernia
Explanation: A direct inguinal hernia protrudes through Hesselbach triangle and lies medial to the inferior epigastric vessels. It is usually acquired from weakness of the transversalis fascia.
6A patient with cavernous sinus thrombosis first develops inability to abduct the right eye before other ocular motor deficits appear. Which nerve is most vulnerable because it runs centrally within the sinus next to the internal carotid artery?
A.Trochlear nerve
B.Abducens nerve
C.Oculomotor nerve
D.Ophthalmic division of trigeminal nerve
Explanation: The abducens nerve runs through the cavernous sinus beside the internal carotid artery rather than in the lateral wall. It is commonly affected early, producing lateral rectus palsy and failure of eye abduction.
7During cardiac auscultation, the second heart sound is heard at the end of systole. What event primarily produces S2?
A.Opening of the mitral and tricuspid valves
B.Closure of the mitral and tricuspid valves
C.Closure of the aortic and pulmonary valves
D.Rapid ventricular filling
Explanation: S2 is produced by closure of the semilunar valves, the aortic and pulmonary valves, marking the end of systole. Physiologic splitting occurs because inspiration delays pulmonic valve closure.
8A sedated patient hypoventilates and retains carbon dioxide. Which acid-base disorder is expected first?
A.Respiratory acidosis
B.Respiratory alkalosis
C.Metabolic acidosis
D.Metabolic alkalosis
Explanation: Hypoventilation raises arterial carbon dioxide, which increases carbonic acid and lowers pH. The primary disturbance is respiratory acidosis, with renal bicarbonate retention developing later if the process persists.
9A dehydrated patient secretes more antidiuretic hormone. In the kidney, ADH increases water reabsorption mainly by inserting which channel into collecting duct principal cells?
A.ENaC
B.Aquaporin-2
C.ROMK
D.Na-K-2Cl cotransporter
Explanation: ADH binds V2 receptors on collecting duct principal cells, increasing cAMP and inserting aquaporin-2 water channels into the apical membrane. This allows water reabsorption and concentrates urine.
10Pulmonary function testing in a patient with pulmonary fibrosis shows reduced total lung capacity and reduced FEV1, but the FEV1/FVC ratio is normal or increased. What physiologic abnormality explains this pattern?
A.Increased airway resistance from bronchospasm
B.Reduced lung compliance from stiff lung parenchyma
C.Loss of elastic recoil from alveolar wall destruction
D.Upper airway obstruction with variable inspiratory flow
Explanation: Restrictive lung disease such as pulmonary fibrosis reduces lung compliance and total lung capacity. FEV1 and FVC both fall, but FVC often falls proportionally more, so the FEV1/FVC ratio is preserved or increased.
About the Philippines PLE Practice Questions
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