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100+ Free Philippines PLE Practice Questions

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An undernourished patient with alcoholism presents with confusion, ataxia, and ophthalmoplegia. Why should thiamine be given before a dextrose load?

A
B
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to track
2026 Statistics

Key Facts: Philippines PLE Exam

12

Official PLE Subjects

Medical Act of 1959 and PRC March 2026 Program

4 days

March 2026 PRC Program Length

PRC March 2026 Physicians Licensure Examination Program

75%

General Average Passing Rule

Republic Act No. 2382

70.3%

March 2026 Pass Rate

PRC March 2026 PLE Results

PHP fee not published

Public Fee Status

PRC Medicine requirements page reviewed

Prepare for the PLE as a broad, integrated medical licensure exam: six basic-science and therapeutic subjects, five major clinical/public-health subjects, and legal medicine/ethics. The official pass rule is a 75% general average with higher minimum floors in Medicine, Pediatrics and Nutrition, Obstetrics and Gynecology, and Preventive Medicine and Public Health. The exam fee was not found on the public PRC Medicine requirements page reviewed, so candidates should verify it directly in PRC Online Services.

Sample Philippines PLE Practice Questions

Try these sample questions to test your Philippines PLE exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1A man has a deep laceration at the fibular neck after a motorcycle crash. On examination, he cannot dorsiflex the foot and has sensory loss over the dorsum of the foot. Which nerve is most likely injured?
A.Common fibular nerve
B.Tibial nerve
C.Femoral nerve
D.Obturator nerve
Explanation: The common fibular nerve winds around the fibular neck and is vulnerable to trauma at that site. Injury causes foot drop from loss of anterior compartment dorsiflexors and sensory loss over the dorsum of the foot.
2After thyroid surgery, a patient develops persistent hoarseness and difficulty abducting the vocal cord on laryngoscopy. Which structure was most likely injured?
A.External branch of the superior laryngeal nerve
B.Recurrent laryngeal nerve
C.Hypoglossal nerve
D.Glossopharyngeal nerve
Explanation: The recurrent laryngeal nerve supplies nearly all intrinsic muscles of the larynx, including the posterior cricoarytenoid muscle that abducts the vocal cord. Injury during thyroidectomy classically causes hoarseness and impaired vocal cord movement.
3A biopsy of normal skin from the palm shows a thick epidermis designed to resist abrasion. What type of epithelium lines this surface?
A.Simple cuboidal epithelium
B.Pseudostratified ciliated columnar epithelium
C.Keratinized stratified squamous epithelium
D.Transitional epithelium
Explanation: The epidermis is keratinized stratified squamous epithelium. Multiple cell layers resist mechanical trauma, and the keratin layer is especially thick in palms and soles.
4A man with cirrhosis develops massive hematemesis from esophageal varices. The varices form at an anastomosis between the left gastric vein and which systemic vein?
A.Azygos vein
B.Inferior vena cava
C.Splenic vein
D.Superior mesenteric vein
Explanation: Esophageal varices form where portal venous flow through the left gastric vein communicates with systemic esophageal veins draining to the azygos system. Portal hypertension dilates this collateral pathway and makes it prone to life-threatening bleeding.
5A groin bulge passes medial to the inferior epigastric vessels through Hesselbach triangle. Which diagnosis best fits this anatomy?
A.Femoral hernia
B.Indirect inguinal hernia
C.Direct inguinal hernia
D.Obturator hernia
Explanation: A direct inguinal hernia protrudes through Hesselbach triangle and lies medial to the inferior epigastric vessels. It is usually acquired from weakness of the transversalis fascia.
6A patient with cavernous sinus thrombosis first develops inability to abduct the right eye before other ocular motor deficits appear. Which nerve is most vulnerable because it runs centrally within the sinus next to the internal carotid artery?
A.Trochlear nerve
B.Abducens nerve
C.Oculomotor nerve
D.Ophthalmic division of trigeminal nerve
Explanation: The abducens nerve runs through the cavernous sinus beside the internal carotid artery rather than in the lateral wall. It is commonly affected early, producing lateral rectus palsy and failure of eye abduction.
7During cardiac auscultation, the second heart sound is heard at the end of systole. What event primarily produces S2?
A.Opening of the mitral and tricuspid valves
B.Closure of the mitral and tricuspid valves
C.Closure of the aortic and pulmonary valves
D.Rapid ventricular filling
Explanation: S2 is produced by closure of the semilunar valves, the aortic and pulmonary valves, marking the end of systole. Physiologic splitting occurs because inspiration delays pulmonic valve closure.
8A sedated patient hypoventilates and retains carbon dioxide. Which acid-base disorder is expected first?
A.Respiratory acidosis
B.Respiratory alkalosis
C.Metabolic acidosis
D.Metabolic alkalosis
Explanation: Hypoventilation raises arterial carbon dioxide, which increases carbonic acid and lowers pH. The primary disturbance is respiratory acidosis, with renal bicarbonate retention developing later if the process persists.
9A dehydrated patient secretes more antidiuretic hormone. In the kidney, ADH increases water reabsorption mainly by inserting which channel into collecting duct principal cells?
A.ENaC
B.Aquaporin-2
C.ROMK
D.Na-K-2Cl cotransporter
Explanation: ADH binds V2 receptors on collecting duct principal cells, increasing cAMP and inserting aquaporin-2 water channels into the apical membrane. This allows water reabsorption and concentrates urine.
10Pulmonary function testing in a patient with pulmonary fibrosis shows reduced total lung capacity and reduced FEV1, but the FEV1/FVC ratio is normal or increased. What physiologic abnormality explains this pattern?
A.Increased airway resistance from bronchospasm
B.Reduced lung compliance from stiff lung parenchyma
C.Loss of elastic recoil from alveolar wall destruction
D.Upper airway obstruction with variable inspiratory flow
Explanation: Restrictive lung disease such as pulmonary fibrosis reduces lung compliance and total lung capacity. FEV1 and FVC both fall, but FVC often falls proportionally more, so the FEV1/FVC ratio is preserved or increased.

About the Philippines PLE Exam

The Philippines Physicians Licensure Examination is the PRC Board of Medicine licensure exam for physician registration. Official PRC and Medical Act sources define 12 subjects: Anatomy and Histology; Physiology; Biochemistry; Microbiology and Parasitology; Pharmacology and Therapeutics; Pathology; Medicine; Obstetrics and Gynecology; Pediatrics and Nutrition; Surgery with Ophthalmology, Otolaryngology and Rhinology; Preventive Medicine and Public Health; and Legal Medicine, Ethics and Medical Jurisprudence. PRC's March 2026 program confirms the current four-day administration order, and the Board of Medicine Table of Specifications gives 100-item subject tables.

Assessment

Twelve subjects administered as two-hour sessions across four PRC exam days. Starting with the March 2026 PLE order: Physiology; Legal Medicine, Medical Jurisprudence and Medical Ethics; Pathology; Biochemistry; Anatomy and Histology; Microbiology and Parasitology; Obstetrics and Gynecology; Pediatrics and Nutrition; Preventive Medicine; Pharmacology and Therapeutics; Surgery; Medicine.

Time Limit

Four exam days; 12 two-hour subject sessions, or 24 subject testing hours total.

Passing Score

75% general average, with no grade lower than 65% in Medicine, Pediatrics and Nutrition, Obstetrics and Gynecology, and Preventive Medicine and Public Health, and no grade lower than 50% in the rest of the subjects.

Exam Fee

Not published on the PRC Medicine requirements page reviewed; verify the current fee in PRC Online Services or with the relevant PRC Regional Office before filing. (Professional Regulation Commission Philippines - Professional Regulatory Board of Medicine)

Philippines PLE Exam Content Outline

100-item subject

Anatomy and Histology

Thorax, abdomen, pelvis and perineum, limbs, head, neck, skin and appendages, and core histology with clinical localization.

100-item subject

Physiology

Cellular homeostasis and organ-system physiology across cardiovascular, respiratory, gastrointestinal, endocrine, renal, reproductive, and nervous systems.

100-item subject

Biochemistry

Metabolism, enzymes, genetics, molecular biology, hemoglobin and acid-base chemistry, nutrition, immunology, and biochemical mechanisms of disease.

100-item subject

Microbiology and Parasitology

Bacterial, viral, fungal, and parasitic diseases organized by organ system, including TB, dengue, malaria, rabies, leptospirosis, enteric infections, and HIV/AIDS.

100-item subject

Pathology

Cell injury, inflammation, neoplasia, immunopathology, environmental and nutritional disease, infection, and organ-system pathology.

100-item subject

Pharmacology and Therapeutics

Therapeutic choices, mechanisms, adverse effects, drug interactions, and monitoring across cardiovascular, neurologic, respiratory, genitourinary, digestive, endocrine, cutaneous, and musculoskeletal conditions.

100-item subject

Medicine

Clinical diagnosis and management in cardiovascular, dermatologic, digestive, endocrine, hematology/immunology, psychiatry, renal, respiratory, rheumatology, neurology, and rehabilitation medicine.

100-item subject

Surgery

Basic surgical principles, shock, trauma, burns, surgical infection, abdomen, head and neck, breast, hernia, neurosurgery, ophthalmology, TCVS, urology, gynecology, plastics, orthopedics, and pediatric surgery.

100-item subject

Obstetrics and Gynecology

Labor, prenatal care, hemorrhage, early pregnancy bleeding, fetal complications, hypertension and diabetes in pregnancy, medical illness in pregnancy, and gynecologic conditions.

100-item subject

Pediatrics and Nutrition

Newborn assessment, nutrition, growth and development, immunization, infections, respiratory, cardiovascular, neurologic, gastrointestinal, and emergency pediatric care.

100-item subject

Preventive Medicine and Public Health

Primary care, Philippine health system, DOH programs, epidemiology, outbreak response, environmental health, health promotion, research, biostatistics, public-health laws, and disaster risk reduction.

100-item subject

Legal Medicine, Medical Jurisprudence and Medical Ethics

Medicolegal examination, death certification, regulation of medical practice, malpractice, physician relationships, and bioethical principles.

How to Pass the Philippines PLE Exam

What You Need to Know

  • Passing score: 75% general average, with no grade lower than 65% in Medicine, Pediatrics and Nutrition, Obstetrics and Gynecology, and Preventive Medicine and Public Health, and no grade lower than 50% in the rest of the subjects.
  • Assessment: Twelve subjects administered as two-hour sessions across four PRC exam days. Starting with the March 2026 PLE order: Physiology; Legal Medicine, Medical Jurisprudence and Medical Ethics; Pathology; Biochemistry; Anatomy and Histology; Microbiology and Parasitology; Obstetrics and Gynecology; Pediatrics and Nutrition; Preventive Medicine; Pharmacology and Therapeutics; Surgery; Medicine.
  • Time limit: Four exam days; 12 two-hour subject sessions, or 24 subject testing hours total.
  • Exam fee: Not published on the PRC Medicine requirements page reviewed; verify the current fee in PRC Online Services or with the relevant PRC Regional Office before filing.

Keys to Passing

  • Complete 500+ practice questions
  • Score 80%+ consistently before scheduling
  • Focus on highest-weighted sections
  • Use our AI tutor for tough concepts

Philippines PLE Study Tips from Top Performers

1Use the PRC subject order to plan full-day review cycles and avoid neglecting subjects scheduled late in the four-day sequence.
2Treat the basic sciences clinically: anatomy localization, physiology mechanisms, biochemical pathways, microbiology diagnosis, pathology mechanisms, and pharmacology safety are all tested through cases.
3Give extra remediation time to Medicine, Pediatrics, Obstetrics and Gynecology, and Preventive Medicine because the Medical Act sets a higher minimum grade floor for these subjects.
4Practice Philippine public-health scenarios, including TB, dengue, rabies exposure, immunization, outbreak investigation, and primary care decision-making.
5For legal medicine and ethics, memorize the pass rule, professional-discipline themes, death certification logic, consent, confidentiality, and malpractice elements.

Frequently Asked Questions

Does the Philippines PLE officially exist?

Yes. PRC publishes Medicine board information, annual examination schedules, PLE programs, Board of Medicine tables of specifications, and official results for the Physicians Licensure Examination.

How many subjects are on the PLE?

The Medical Act lists 12 subjects, and PRC's March 2026 program administers those subjects across four examination days.

How is the PLE passing score determined?

The Medical Act requires a 75% general average, with no grade lower than 65% in Medicine, Pediatrics and Nutrition, Obstetrics and Gynecology, and Preventive Medicine and Public Health, and no grade lower than 50% in the other subjects.

How much is the PLE exam fee?

The specific Medicine PLE examination fee was not published on the PRC Medicine requirements page reviewed for this metadata. Candidates should verify the current amount in PRC Online Services or with the relevant PRC Regional Office.

Are these official PRC questions?

No. These are original practice questions aligned to official PRC subjects and public tables of specifications. They do not copy official copyrighted examination questions.