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100+ Free Hospital Pharmacy (China) Practice Questions

Prepare for the National Health Professional and Technical Qualification Examination — Pharmacy Series (全国卫生专业技术资格考试·药学专业 101/201/366) exam with instant access — no signup required.

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2026 Statistics

Key Facts: Hospital Pharmacy (China) Exam

100 / 90 min

100 multiple-choice questions in 90 minutes per subject paper

21wecan Examination Regulations

60 Points

National standardized passing mark out of 100 on each paper

MOHRSS Health Title Standard Setting

2 Years

Rolling credit validity window to pass all 4 subject papers

21wecan National Examination Scheme

4 Papers

Basic Knowledge, Related Professional, Professional, and Practical Ability

NHC Talent Center Official Syllabus

101/201/366

Official specialty codes for Junior Assistant, Junior Pharmacist, and Supervisor Pharmacist

National Health Professional Qualification Directory

The National Health Professional Qualification Examination (Pharmacy Series 101/201/366) is the statutory hospital title qualification for pharmacy technicians, junior pharmacists, and supervisor pharmacists in China. Administered by NHC (21wecan), candidates must score at least 60/100 on all 4 papers (Basic Knowledge, Related Professional Knowledge, Professional Knowledge, and Professional Practice Ability) within a 2-year rolling window. This 100-question practice set provides targeted single-best-answer questions with detailed distractor rationales and authentic Chinese clinical pharmacy terms.

Sample Hospital Pharmacy (China) Practice Questions

Try these sample questions to test your Hospital Pharmacy (China) exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1In human cellular physiology, which transport mechanism is responsible for moving Na+ out of the cell and K+ into the cell against their respective concentration gradients, consuming ATP in the process (主动转运)?
A.Sodium-potassium adenosine triphosphatase pump (Na+/K+-ATPase 钠钾泵)
B.Voltage-gated sodium channel facilitated diffusion (电压门控钠通道易化扩散)
C.Simple lipid bilayer passive diffusion (简单扩散)
D.Potassium leak channel passive efflux (钾漏通道被动外流)
Explanation: Primary active transport (原发性主动转运) moves ions across the plasma membrane against electrochemical gradients using energy directly derived from ATP hydrolysis. The Na+/K+-ATPase pump expels 3 Na+ ions from the intracellular compartment in exchange for importing 2 K+ ions per ATP molecule hydrolyzed, maintaining resting membrane potential and cell volume.
2During the action potential of ventricular cardiac working myocytes (心室肌动作电位), which ionic current is primarily responsible for the characteristic Phase 2 plateau (2期平台期)?
A.Fast inward Na+ current via Nav1.5 channels (INa)
B.Inward Ca2+ current via L-type calcium channels (ICa-L) balanced by delayed rectifier outward K+ current (IK)
C.Transient outward K+ current (Ito)
D.Inward rectifier K+ current maintaining resting potential (IK1)
Explanation: Phase 2 (plateau phase / 平台期) of the ventricular cardiac action potential is characterized by a balance between the slow inward flow of Ca2+ through L-type calcium channels (ICa-L) and the outward flow of K+ through delayed rectifier potassium channels (IK). This prolonged plateau prolongs the effective refractory period (ERP), preventing tetanic cardiac contraction.
3In renal physiology, which hemodynamic factor directly reduces the Effective Filtration Pressure (EFP / 有效滤过压) and therefore decreases the Glomerular Filtration Rate (GFR / 肾小球滤过率)?
A.Moderate constriction of the renal efferent arteriole (出球小动脉中度收缩)
B.Infusion of normal saline causing decreased plasma colloid osmotic pressure (血浆胶体渗透压降低)
C.Severe ureteral obstruction causing increased Bowman's capsule hydrostatic pressure (肾小囊内压升高)
D.Increase in mean arterial blood pressure from 90 mmHg to 120 mmHg (肾血流自身调节范围内血压升高)
Explanation: Effective Filtration Pressure (EFP) is defined as: EFP = Glomerular Capillary Hydrostatic Pressure - (Plasma Colloid Osmotic Pressure + Bowman's Capsule Hydrostatic Pressure). Ureteral obstruction or urinary tract stones back up tubular fluid, markedly increasing Bowman's capsule hydrostatic pressure (肾小囊内压), which opposes filtration and reduces GFR.
4Which adrenergic receptor subtype is predominantly located on bronchial smooth muscle and vascular smooth muscle of skeletal muscle, mediating relaxation and bronchodilation upon activation (支气管平滑肌舒张)?
A.Alpha-1 adrenergic receptor (α1受体)
B.Beta-1 adrenergic receptor (β1受体)
C.Alpha-2 adrenergic receptor (α2受体)
D.Beta-2 adrenergic receptor (β2受体)
Explanation: Beta-2 adrenergic receptors (β2受体) are coupled to Gs proteins, stimulating adenylate cyclase to increase intracellular cAMP, which activates protein kinase A (PKA) and promotes smooth muscle relaxation. Activation of β2 receptors produces bronchodilation, vasodilation in skeletal muscle vascular beds, and glycogenolysis in the liver.
5In enzyme kinetics (酶促反应动力学), how does a competitive reversible inhibitor (竞争性抑制剂) alter the Michaelis constant (Km) and maximum velocity (Vmax)?
A.Km increases, while Vmax remains unchanged (Km增大，Vmax不变)
B.Km decreases, while Vmax decreases (Km减小，Vmax减小)
C.Km remains unchanged, while Vmax decreases (Km不变，Vmax减小)
D.Both Km and Vmax increase proportionally (Km和Vmax均增大)
Explanation: A competitive inhibitor structurally resembles the natural substrate and competes for the active catalytic site of the free enzyme. Increasing substrate concentration can overcome the inhibition: therefore, the apparent affinity decreases (Km increases), but the maximal reaction velocity (Vmax) remains unchanged when substrate is saturating.
6In cellular carbohydrate metabolism, which enzyme functions as the primary, rate-limiting regulatory valve of the glycolysis pathway (糖酵解限速酶) and is allosterically activated by Fructose-2,6-bisphosphate (F-2,6-BP)?
A.Hexokinase / Glucokinase (己糖激酶/葡萄糖激酶)
B.Phosphofructokinase-1 (PFK-1 / 6-磷酸果糖激酶-1)
C.Pyruvate kinase (丙酮酸激酶)
D.Phosphoglycerate kinase (磷酸甘油酸激酶)
Explanation: Phosphofructokinase-1 (PFK-1 / 6-磷酸果糖激酶-1) catalyzes the irreversible phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. It is the principal rate-limiting enzyme of glycolysis, strongly inhibited by high ATP and citrate, and allosterically activated by AMP, ADP, and its potent physiological activator Fructose-2,6-bisphosphate (F-2,6-BP).
7Which plasma lipoprotein particle possesses the highest density of protein, contains Apolipoprotein A-I (ApoA-I), and mediates reverse cholesterol transport (胆固醇逆向转运) from peripheral tissues back to the liver?
A.Chylomicrons (乳糜微粒 CM)
B.Very Low-Density Lipoprotein (极低密度脂蛋白 VLDL)
C.High-Density Lipoprotein (高密度脂蛋白 HDL)
D.Low-Density Lipoprotein (低密度脂蛋白 LDL)
Explanation: High-Density Lipoprotein (HDL / 高密度脂蛋白) contains the highest proportion of protein and the lowest lipid content. Its major structural apolipoprotein is ApoA-I, which activates LCAT (lecithin-cholesterol acyltransferase) to esterify cholesterol, picking up excess cholesterol from peripheral arterial wall macrophages and transporting it back to the liver for excretion (reverse cholesterol transport).
8In medical microbiology, what structural component is uniquely present in the outer membrane of Gram-negative bacteria (革兰阴性菌外膜) that acts as an endotoxin (内毒素)?
A.Teichoic acid (磷壁酸)
B.Thick cross-linked peptidoglycan (厚层肽聚糖)
C.Sterols and ergosterol (麦角甾醇)
D.Lipopolysaccharide containing Lipid A (脂多糖 LPS / 脂质A)
Explanation: Lipopolysaccharide (LPS / 脂多糖) is the distinctive major constituent of the outer leaflet of the outer membrane in Gram-negative bacteria. LPS consists of O-antigen, core polysaccharide, and Lipid A (脂质A). Lipid A is responsible for the endotoxic shock, pyrogenicity, fever induction, and macrophage activation observed during Gram-negative sepsis.
9Which molecular mechanism represents the primary enzymatic basis for Extended-Spectrum Beta-Lactamase (ESBL / 超广谱β-内酰胺酶) producing Enterobacterales conferring resistance to 3rd-generation cephalosporins?
A.Plasmid-mediated hydrolysis of penicillins, cephalosporins, and aztreonam, inhibited by clavulanic acid or tazobactam (质粒介导水解头孢菌素，可被酶抑制剂抑制)
B.Mutational alteration of DNA gyrase subunit GyrA preventing quinolone binding
C.Active efflux pump overexpression eliminating aminoglycosides
D.Ribosomal methylation via erm genes blocking macrolide binding
Explanation: ESBLs (such as CTX-M, TEM, and SHV derivatives) are Class A beta-lactamases that hydrolyze oxyimino-beta-lactams (cefotaxime, ceftriaxone, ceftazidime) and monobactams (aztreonam), but do NOT hydrolyze cephamycins (cefoxitin) or carbapenems. Crucially, ESBLs are characteristically inhibited in vitro by beta-lactamase inhibitors like clavulanic acid, tazobactam, and sulbactam.
10Which biochemical pathway and specific fungal enzyme are targeted by triazole antifungal agents such as fluconazole and voriconazole (三唑类抗真菌药作用靶点)?
A.Inhibition of squalene epoxidase in squalene pathway
B.Inhibition of cytochrome P450-dependent Lanosterol 14α-demethylase (CYP51 / 羊毛甾醇14α-去甲基酶)
C.Inhibition of β-(1,3)-D-glucan synthase in cell wall assembly
D.Inhibition of fungal DNA topoisomerase II
Explanation: Azole antifungals (triazoles like fluconazole, voriconazole, itraconazole) selectively inhibit fungal cytochrome P450-dependent Lanosterol 14α-demethylase (encoded by ERG11 / CYP51). This blocks the conversion of lanosterol to ergosterol, leading to ergosterol depletion and accumulation of toxic 14α-methylated sterols that disrupt fungal membrane permeability and inhibit fungal growth.

About the Hospital Pharmacy (China) Exam

The National Health Professional and Technical Qualification Examination for Pharmacy (全国卫生专业技术资格考试·药学专业 101/201/366) is the official statutory professional title examination administered by the National Health Commission Talent Exchange Center (21wecan) and MOHRSS for clinical pharmacists and pharmacy technicians in Chinese medical institutions. The examination tests foundational medical sciences (physiology, biochemistry, pathology), pharmaceutical chemistry and analysis, pharmaceutics, hospital pharmacy regulations and narcotics management, systemic pharmacology, clinical pharmacokinetics, therapeutic drug monitoring (TDM), centralized intravenous admixture services (PIVAS), and individualized pharmacotherapy.

Assessment

Four computer-based (人机对话) papers: Basic Knowledge (基础知识, 90 min, 100 MCQs), Related Professional Knowledge (相关专业知识, 90 min, 100 MCQs), Professional Knowledge (专业知识, 90 min, 100 MCQs), and Professional Practice Ability (专业实践能力, 90 min, 100 MCQs).

Time Limit

90 minutes per subject (total 360 minutes / 6.0 hours across 4 sessions)

Passing Score

60 out of 100 points per paper (fixed national passing standard set by MOHRSS/NHC, 2-year rolling cycle)

Exam Fee

Set provincially; Hunan's 2026 notice charges RMB 70 per subject (National Health Commission Talent Exchange Center (国家卫生健康委人才交流服务中心 / 21wecan) & MOHRSS)

Hospital Pharmacy (China) Exam Content Outline

20%

Basic Medical Sciences, Physiology & Biochemistry (基础知识：生理生化、微生物与药物化学)

Human physiology, organ function regulation, cellular biochemical pathways, enzyme kinetics, medical microbiology, antimicrobial resistance mechanisms, medicinal chemistry structures, and analytical spectroscopy

20%

Hospital Pharmacy Management & Regulations (相关专业知识：药事管理与药剂学基础)

PRC Drug Administration Law, hospital pharmacy management, prescription auditing rules (处方点评), special controlled substances (麻醉药品与第一类精神药品), antimicrobial stewardship grading, and pharmaceutical dosage forms

30%

Pharmacology & Bio-pharmaceutics (专业知识：药理学与生物药剂学)

Cardiovascular, antimicrobial, neurological, respiratory, endocrine, and antineoplastic pharmacology, receptor mechanisms, adverse drug reactions, pharmacodynamics, drug interactions, and pharmacokinetic absorption/distribution

30%

Hospital Dispensing, Clinical Pharmacokinetics, TDM & Clinical Pharmacy Practice (专业实践能力：临床药物治疗学与医院药事实务)

Outpatient/inpatient dispensing procedures, PIVAS sterile preparation techniques, therapeutic drug monitoring (TDM) of narrow therapeutic index drugs (vancomycin, digoxin, theophylline, phenytoin), individualized dosing regimens, and disease pharmacotherapy guidelines

How to Pass the Hospital Pharmacy (China) Exam

What You Need to Know

  • Passing score: 60 out of 100 points per paper (fixed national passing standard set by MOHRSS/NHC, 2-year rolling cycle)
  • Assessment: Four computer-based (人机对话) papers: Basic Knowledge (基础知识, 90 min, 100 MCQs), Related Professional Knowledge (相关专业知识, 90 min, 100 MCQs), Professional Knowledge (专业知识, 90 min, 100 MCQs), and Professional Practice Ability (专业实践能力, 90 min, 100 MCQs).
  • Time limit: 90 minutes per subject (total 360 minutes / 6.0 hours across 4 sessions)
  • Exam fee: Set provincially; Hunan's 2026 notice charges RMB 70 per subject

Keys to Passing

  • Work through all 100 available questions
  • Review every answer and explanation
  • Track weak areas and revisit them
  • Use our AI tutor for tough concepts

Hospital Pharmacy (China) Study Tips from Top Performers

1Memorize special controlled drug regulations: Dual-person dual-lock (双人双锁), dedicated prescription pads (麻醉药品专用处方, light red), and maximum prescription quantities (1 dose for emergency injection, 3-day supply for common tablets, 7-day supply for chronic severe pain sustained-release preparations).
2Master pharmacokinetic calculations: Elimination rate constant (k = 0.693 / t1/2), Volume of distribution (Vd = Dose / C0), Clearance (CL = k * Vd), and Loading dose (Loading Dose = Target Conc * Vd).
3Understand Therapeutic Drug Monitoring (TDM) ranges and sampling times: Vancomycin trough (10–20 mg/L, 15–20 mg/L for severe MRSA), Digoxin therapeutic range (0.5–0.9 ng/mL for HF, 0.8–2.0 ng/mL for AF), Theophylline (5–15 mg/L), Lithium (0.6–1.2 mmol/L).
4Know PIVAS sterile preparation requirements: ISO Class 5 (Grade A / 百级) laminar airflow biological safety cabinets inside an ISO Class 7 (Grade B / 万级) clean room environment for hazardous/antineoplastic admixtures.
5Review antimicrobial stewardship classification: Non-restricted (非限制使用级), Restricted (限制使用级), and Special use (特殊使用级 - requires senior physician authorization and clinical pharmacist consultation).

Frequently Asked Questions

What is the difference between the Health Title Exam (卫生职称药学) and the Licensed Pharmacist Exam (执业药师)?

The Health Professional Qualification Exam (卫生职称考试, codes 101/201/366) is administered by the National Health Commission (21wecan) for pharmacists working within hospitals and healthcare institutions to obtain clinical professional titles (药士/药师/主管药师). The Licensed Pharmacist Exam (执业药师) is administered by the National Medical Products Administration (NMPA) and MOHRSS for practicing in retail community pharmacies and pharmaceutical wholesale/manufacturing enterprises.

What question types appear in the computer-based (人机对话) exam?

The exam consists entirely of objective multiple-choice items: A1/A2 type (single-statement and single-patient scenario single best answer), A3/A4 type (patient clinical case vignette with multiple progressive questions), and B1 type (matching drug/mechanism to numbered options).

What is the passing score and retake policy?

Each of the 4 subject papers is scored out of 100 points, with a nationally standardized passing mark of 60 points. Scores are managed on a 2-year rolling cycle: passing grades for individual papers remain valid for two consecutive examination calendar years.