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Free Practice Questions for BCPPS

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Key Facts: BCPPS Exam

150

Total Questions

125 scored + 25 unscored

3h 45m

Testing Time

BCPPS Examination Specifications

66%

Pass Rate

BPS first-time

$600

Application Fee

BPS 2026

7 years

Certification Valid

Recertification cycle

4 yrs

Practice Pathway

or PGY1 + 2 yrs, or PGY2

The BCPPS exam has a pass rate near 66% for first-time candidates. It is a 150-item computer-based BPS examination (125 scored and 25 unscored items) with 3 hours 45 minutes of testing time. Eligibility requires an active pharmacist license plus, within the past 7 years, one of: 4 years of pediatric pharmacy practice, PGY1 residency plus 2 years of pediatric practice, or a PGY2 pediatric pharmacy residency. The 2026 application fee is $600 ($300 retake) and certification is valid 7 years.

Sample BCPPS Practice Questions

Try these sample questions to review concepts for the BCPPS exam. Each question includes a detailed explanation. Start the interactive quiz above for the full 120+ question experience with AI tutoring.

1Which enzyme is the dominant CYP450 isoenzyme expressed in the fetal and early neonatal liver that subsequently declines as CYP3A4 matures?
A.CYP2D6
B.CYP3A7
C.CYP2C9
D.CYP1A2
Explanation: CYP3A7 is the principal fetal/neonatal CYP3A isoform. Its activity declines within the first weeks to months of life as CYP3A4 expression rises, contributing to the age-dependent clearance of many substrates (e.g., midazolam, fentanyl).
2Immature UGT-mediated glucuronidation in neonates is MOST classically associated with toxicity from which antibiotic?
A.Vancomycin
B.Gentamicin
C.Chloramphenicol
D.Ceftriaxone
Explanation: Chloramphenicol is conjugated by UGT2B7 glucuronidation. Neonates have immature UGT activity, causing accumulation and the classic 'gray baby syndrome' (cyanosis, cardiovascular collapse, abdominal distension).
3A 3-month-old term infant weighs 6 kg. Using 80 mg/kg/day of amoxicillin for acute otitis media, what is the appropriate total daily dose?
A.240 mg/day
B.360 mg/day
C.480 mg/day
D.960 mg/day
Explanation: 80 mg/kg/day x 6 kg = 480 mg/day, typically divided twice daily (240 mg BID). Guidelines recommend 80-90 mg/kg/day for acute otitis media to overcome intermediate-resistance pneumococci.
4Which intramuscular injection site is preferred for a healthy 4-month-old infant receiving routine vaccines?
A.Deltoid
B.Vastus lateralis
C.Dorsogluteal
D.Ventrogluteal
Explanation: The vastus lateralis (anterolateral thigh) is recommended for IM injections in infants <12 months. The deltoid is used starting at ~12-18 months of age when muscle mass is adequate.
5Which commercially available suspending vehicle is commonly used for extemporaneous pediatric oral suspensions to provide both suspension and sweetening?
A.Simple syrup alone
B.Ora-Plus and Ora-Sweet (1:1)
C.Sterile water for irrigation
D.Polyethylene glycol 400
Explanation: A 1:1 mix of Ora-Plus (suspending vehicle) and Ora-Sweet (flavored/sweetened vehicle) is a widely used combination for pediatric extemporaneous suspensions to provide uniform suspension and palatability.
6A premature infant has apnea of prematurity. What is the drug of choice?
A.Theophylline
B.Caffeine citrate
C.Albuterol
D.Doxapram
Explanation: Caffeine citrate is the agent of choice for apnea of prematurity. It has a wide therapeutic window, long half-life allowing once-daily dosing, and improved outcomes (reduced BPD, cerebral palsy) shown in the CAP trial.
7Empiric therapy for early-onset neonatal sepsis most commonly includes which regimen?
A.Vancomycin + cefepime
B.Ampicillin + gentamicin
C.Ceftriaxone monotherapy
D.Piperacillin-tazobactam monotherapy
Explanation: Early-onset sepsis (<72 hours) pathogens are Group B Streptococcus, E. coli, and Listeria. Ampicillin + gentamicin is the standard empiric regimen covering these organisms synergistically.
8What is the preferred first-line inhaled medication for acute asthma exacerbation in children?
A.Ipratropium
B.Short-acting beta-2 agonist (albuterol)
C.Inhaled corticosteroid
D.Salmeterol
Explanation: Short-acting beta-2 agonists (SABAs) like albuterol are first-line bronchodilators for acute asthma exacerbation due to rapid onset and direct smooth-muscle relaxation.
9Which medication is first-line for croup (laryngotracheobronchitis) in a 2-year-old?
A.Dexamethasone
B.Amoxicillin
C.Albuterol
D.Acetaminophen
Explanation: A single dose of dexamethasone (typically 0.6 mg/kg PO/IV/IM, max 16 mg) is first-line treatment for croup, reducing inflammation and severity. Racemic epinephrine is added for moderate-severe cases.
10Per the 2026 CDC ACIP schedule, the first dose of hepatitis B vaccine should be administered at what age?
A.Birth (within 24 hours)
B.1 month
C.2 months
D.6 months
Explanation: HepB vaccine dose #1 is given within 24 hours of birth for all medically stable infants ≥2 kg, per ACIP, to prevent perinatal hepatitis B transmission. Infants of HBsAg-positive mothers also receive HBIG within 12 hours.

About the BCPPS Exam

The BCPPS certification recognizes pharmacists with advanced knowledge of pediatric pharmacotherapy from neonates through adolescents. The 150-item BPS exam (125 scored, 25 unscored) is delivered through Pearson VUE and covers the pediatric patient population, therapeutics and patient management, and professional practice.

Exam sponsor: Board of Pharmacy Specialties (BPS). The requirements and fees below concern the certification or admission exam, separate from our free practice resources.

Questions

150 questions

Time Limit

3 hours 45 minutes

Passing Score

Scaled (BPS 75 scale)

Exam / Certification Fees

$600

Exam sponsor website

Reported exam pass rate: ~66%. BPS BCPPS first-time candidates This describes exam candidates, not OpenExamPrep users or results from using our resources. Exam sponsor website

Fees, eligibility, and exam policies can change. Confirm them with the exam sponsor before applying or paying.

Our practice resources: topics covered

We aim to reflect publicly available exam outlines and topic information in our study resources. Coverage, format, and difficulty may differ from the actual exam, and we cannot guarantee that every detail is accurate or current. Confirm exam requirements, fees, and policies with the official exam sponsor.

26%

Pediatric Patient Population

1A Pediatric Patient Characteristics (11%): normal growth and development, developmental pharmacokinetics, pathophysiology, anthropometrics (growth curves, BSA), pregnancy and lactation. 1B Pediatric Patient-Care Considerations (15%): common health issues, immunizations, nutrition and hydration, age-appropriate interviewing, laboratory practices, and pediatric calculations (fluid requirements, renal function estimates).

50%

Therapeutics and Patient Management

2A Treatment Planning (16%): history, diagnosis, pharmacodynamics and pharmacokinetics, pharmacogenomics, goals of care, social determinants of health, pediatric doses and dosage forms. 2B Therapeutic Implementation (18%): pharmacotherapy, non-drug treatment, care coordination, medication reconciliation, medication delivery, family and caregiver education, pediatric emergency response (NRP, PALS). 2C Treatment Outcomes and Monitoring (16%): therapeutic targets, monitoring, adverse drug events, drug interactions, laboratory assessment, pediatric scoring systems (CAPD, WAT-1).

24%

Professional Practice

3A Quality of Care (12%): population health, preventive care, continuity of care, clinical practice guidelines, medication safety. 3B Practice Management (12%): practice standards and regulations, ethics and advocacy, research methods and statistics, pediatric subjects research (IRB/IEC, consent), pharmacoeconomics, clinical informatics, emergency preparedness and drug shortages.

Preparing for the BCPPS Exam

What You Need to Know

  • Passing score: Scaled (BPS 75 scale)
  • Exam length: 150 questions
  • Time limit: 3 hours 45 minutes
  • Exam / certification fees: $600 Official sources

Using Our Practice Resources

  • Work through all 120 available questions
  • Review every answer and explanation
  • Track weak areas and revisit them
  • Use our AI tutor for tough concepts

BCPPS: Suggested Study Strategy

1Master developmental pharmacokinetics — memorize CYP maturation timelines (CYP3A7 to CYP3A4 switch, CYP2D6, CYP2C9/2C19) and UGT glucuronidation gaps explaining chloramphenicol and morphine neonatal toxicity
2Drill weight-based dosing and maximum-dose caps cold — amoxicillin 80-90 mg/kg/day for AOM, ceftriaxone max 2 g/day, acetaminophen 15 mg/kg q4-6h (max 75 mg/kg/day)
3Know the 2026 ACIP pediatric schedule including PCV15/PCV20, RSV (nirsevimab/Beyfortus vs palivizumab), HPV, and meningococcal ACWY and B
4Study neonatal sepsis pathogens (GBS, E. coli, Listeria) and empiric regimens (ampicillin + gentamicin for EOS; vancomycin + gentamicin or cefepime for LOS)
5Review USP <795>, <797>, and <800> beyond-use dates and suspending vehicles (Ora-Plus/Ora-Sweet) for pediatric extemporaneous compounding

Frequently Asked Questions

What is the BCPPS pass rate?

The BCPPS first-time pass rate is approximately 66% based on recent BPS continuous-testing results. Scores are reported on the BPS scaled-score system and the cut score is set by the BPS Specialty Council through standard setting.

How many questions are on the BCPPS exam and how long is it?

The BCPPS exam contains 150 multiple-choice items: 125 scored items and 25 unscored items. The administration time is 3 hours 45 minutes.

What are the BCPPS eligibility requirements?

Candidates must have graduated from an ACPE-accredited pharmacy program (or a qualifying program outside the US), hold an active pharmacist license, and meet one of these pathways within the past 7 years: (1) at least 4 years of pediatric pharmacy practice experience, (2) a PGY1 pharmacy residency plus at least 2 years of pediatric pharmacy practice experience, or (3) a PGY2 pediatric pharmacy residency. Practice experience must be post-licensure, with at least 50% of time in the content outline's scope.

How much does the BCPPS exam cost in 2026?

The 2026 BCPPS initial application fee is $600 USD. The retake application fee is $300 USD for candidates who failed the exam within the previous year. The 2026 application window runs February 8 – August 17.

How long is BCPPS certification valid?

BCPPS certification is valid for 7 years. For cycles beginning January 1, 2024 or later, recertify either by passing the examination and reporting 20 units of continuing professional development, or by earning 100 units (at least 80 units of assessed CPE from BPS-approved programs offered by ASHP with ACCP or by the Pediatric Pharmacy Association, plus up to 20 units of self-reported CPD).

What topics are highest yield for BCPPS preparation?

High-yield areas include: neonatal pharmacokinetics and dosing (CYP3A7, glucuronidation, renal clearance maturation), weight-based and BSA dosing, pediatric infectious disease (high-dose amoxicillin for AOM, RSV monoclonals), pediatric asthma/CF (including CFTR modulators), neonatal sepsis (amp + gent), seizures, ADHD, T1DM technology (pumps/CGM/closed-loop), SCD (hydroxyurea/crizanlizumab), ACIP vaccine schedule, and medication-safety in weight-based dosing.