2.1 Airway Anatomy & Assessment
Key Takeaways
The upper airway (nose, mouth, pharynx, larynx) warms, filters, and humidifies inspired gas to 37C and 44 mg/L by the carina
The lower airway runs trachea to alveoli; the carina sits at roughly the 2nd rib / T4-T5 and is densely innervated, triggering cough on stimulation
The right mainstem bronchus is shorter, wider, and more vertical (~25 degrees vs ~45 degrees on the left), so aspiration and tube migration favor the right side
The cricoid cartilage is the only complete (360-degree) ring and the narrowest point of the pediatric airway under ~8 years old
Respiratory distress = compensating (tachypnea, accessory muscle use, tripod, anxiety); impending failure = decompensating (altered mentation, paradoxical breathing, bradycardia, silent chest)
Bradycardia, a falling respiratory rate, and a rising PaCO2 in a tiring patient are ominous late signs that demand immediate ventilatory support
The Mallampati score (I-IV) predicts laryngoscopic difficulty from pharyngeal visualization; III-IV warns to ready rescue airway equipment
The TMC exam (160 questions, 3 hours, 140 scored) tests recognition of distress versus failure as a clinical-judgment skill, not just anatomy recall
Airway Anatomy & Assessment
A precise mental map of the airway is the foundation of every airway-management and oxygenation decision the respiratory therapist (RT) makes. The Therapist Multiple-Choice (TMC) Examination from the National Board for Respiratory Care (NBRC) — 160 items, 3 hours, 140 scored — repeatedly tests anatomy not as trivia but as the reasoning behind tube placement, suction depth, aspiration risk, and the urgent recognition of failing patients.
Upper Airway: The Conditioning Zone
The upper airway extends from the nose and mouth to the larynx and warms, filters, and humidifies inspired gas, delivering it to the carina at roughly 37 degrees C and 44 mg/L absolute humidity.
| Structure | Key feature | Clinical significance |
|---|---|---|
| Nasal cavity | Turbinates warm/humidify; mucosa traps particles | Nasal intubation route; epistaxis risk |
| Oropharynx | Behind the mouth; base of tongue | Most common obstruction site when unconscious |
| Epiglottis | Leaf-shaped cartilage covering the glottis when swallowing | Epiglottitis is an airway emergency |
| Larynx | Houses vocal cords; thyroid and cricoid cartilages | Cricothyrotomy landmark; phonation |
| Glottis | Space between the true vocal cords | Narrowest point of the adult airway |
| Cricoid cartilage | Only complete 360-degree ring | Narrowest point of the pediatric airway (<~8 yr) |
Lower Airway: The Conducting & Gas-Exchange Zone
The lower airway begins at the trachea (10-12 cm, C-shaped rings open posteriorly) and branches at the carina into the mainstem bronchi.
| Structure | Key feature | Clinical significance |
|---|---|---|
| Carina | Bifurcation, ~T4-T5 / 2nd rib | Endotracheal tube (ETT) tip should sit 3-5 cm above it |
| Right mainstem | Shorter, wider, ~25-degree angle | Favored target for aspiration and right-mainstem intubation |
| Left mainstem | Longer, narrower, ~45-degree angle | Less common aspiration/intubation site |
| Bronchioles | No cartilage; smooth muscle | Site of bronchospasm in asthma and COPD |
| Alveoli | ~300 million; Type I gas exchange, Type II surfactant | Final gas-exchange surface |
Worked trap: An intubated patient suddenly loses left-sided breath sounds with a rising peak pressure. Because the right mainstem is more vertical, the ETT has most likely migrated into the right mainstem. The fix is to deflate the cuff, withdraw the tube 1-2 cm, re-auscultate for bilateral sounds, re-inflate, and confirm by chest X-ray (tip 3-5 cm above the carina).
Distress Versus Impending Failure
The single most tested clinical judgment here is separating a compensating patient (distress) from a decompensating one (impending failure). Distress can often be managed with oxygen, bronchodilators, or noninvasive ventilation; impending failure demands an advanced airway.
Respiratory distress — the patient is still working effectively:
- Tachypnea (respiratory rate > 20/min in adults)
- Accessory muscle use (sternocleidomastoid, scalenes, intercostals)
- Nasal flaring; intercostal and suprasternal retractions
- Diaphoresis, agitation, inability to speak full sentences
- Tripod positioning (upright, leaning forward, arms braced)
Impending respiratory failure — the patient is losing the battle:
- Altered mental status (confusion, somnolence, unresponsiveness)
- Paradoxical (abdominal) breathing — abdomen sinks as the chest rises
- Bradycardia and a falling respiratory rate (ominous late signs)
- Central cyanosis of lips and mucous membranes
- Silent chest — no air movement despite visible effort
A classic exam scenario: a severe asthmatic who was loudly wheezing now has a quiet chest, a normalizing (no longer low) PaCO2, and is drowsy. This is not improvement — it is exhaustion and impending failure, and the answer is to prepare for intubation, not to celebrate.
Mallampati Classification
The Mallampati score predicts laryngoscopic difficulty from how much pharyngeal anatomy is visible with the mouth wide open and tongue protruded.
| Class | What is visible | Expected difficulty |
|---|---|---|
| I | Soft palate, fauces, full uvula, pillars | Easy |
| II | Soft palate, fauces, uvula | Usually straightforward |
| III | Soft palate, base of uvula | Potentially difficult |
| IV | Hard palate only | Difficult — ready rescue equipment |
Mallampati is one of several difficult-airway predictors. Others worth recognizing include a thyromental distance under three fingerbreadths (a short, recessed chin), limited mouth opening under three fingerbreadths between the incisors, restricted neck extension, a large tongue or short muscular neck, and obstructive pathology such as airway burns, angioedema, or an expanding hematoma. A high Mallampati class is a flag, not a verdict: it tells the team to optimize positioning, have a video laryngoscope and a supraglottic rescue airway at the bedside, and avoid eliminating spontaneous ventilation until the airway is secured.
Positioning and Pediatric Differences
Proper positioning aligns the oral, pharyngeal, and laryngeal axes. In an adult, the sniffing position — neck flexed on the body with the head extended at the atlanto-occipital joint, often with a pad under the occiput — gives the best laryngoscopic view.
The pediatric airway differs in ways that change technique: the occiput is large (so a shoulder roll, not a head pad, achieves neutral alignment in infants), the tongue is proportionally larger, the larynx sits higher and more anterior (about C3-C4 versus C5-C6 in adults), the epiglottis is longer and floppier (favoring a straight Miller blade), and the cricoid ring is the narrowest point rather than the glottis. These differences explain why pediatric airway obstruction develops quickly and why even small amounts of edema or a slightly oversized tube cause disproportionate airway narrowing in a child.
Putting Assessment Together
Clinical assessment is a continuous loop, not a single snapshot. The RT integrates inspection (work of breathing, color, position, mentation), auscultation (air movement, adventitious sounds, symmetry), vital-sign trends, pulse oximetry, and — when available — arterial blood gases. A patient whose SpO2 holds but whose PaCO2 is climbing while alertness fades is heading toward ventilatory failure even with a 'normal' oxygen number, a pattern the exam uses to test whether you understand that oxygenation and ventilation are separate problems.
A patient is found unresponsive. What is the MOST common cause of upper airway obstruction?
Foreign body aspiration
Epiglottitis
The tongue falling back against the posterior pharynx
Laryngospasm
The right mainstem bronchus is the most common site for aspiration because it is:
Longer, narrower, and more horizontal than the left
Located directly behind the esophagus
The only bronchus with cartilage rings
Shorter, wider, and more vertical than the left
An exhausted asthmatic who was loudly wheezing now has a quiet chest, a PaCO2 that has risen from 30 to 44 mmHg, and is becoming drowsy. This combination indicates:
Successful bronchodilator response, so therapy should continue unchanged
Resolving bronchospasm that allows oxygen to be weaned
A simple anxiety reaction that will resolve with reassurance
Impending respiratory failure requiring preparation for intubation
Which finding is a sign of impending respiratory FAILURE rather than compensated distress?
Tachypnea with accessory muscle use
Tripod positioning with diaphoresis
Paradoxical breathing with altered mental status
Nasal flaring with intercostal retractions
The _____ cartilage is the only complete cartilage ring in the airway and serves as a landmark for cricothyrotomy.
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