2.1 Airway Anatomy & Assessment

Key Takeaways

  • The upper airway (nose, mouth, pharynx, larynx) warms, filters, and humidifies inspired gas to 37C and 44 mg/L by the carina
  • The lower airway runs trachea to alveoli; the carina sits at roughly the 2nd rib / T4-T5 and is densely innervated, triggering cough on stimulation
  • The right mainstem bronchus is shorter, wider, and more vertical (~25 degrees vs ~45 degrees on the left), so aspiration and tube migration favor the right side
  • The cricoid cartilage is the only complete (360-degree) ring and the narrowest point of the pediatric airway under ~8 years old
  • Respiratory distress = compensating (tachypnea, accessory muscle use, tripod, anxiety); impending failure = decompensating (altered mentation, paradoxical breathing, bradycardia, silent chest)
  • Bradycardia, a falling respiratory rate, and a rising PaCO2 in a tiring patient are ominous late signs that demand immediate ventilatory support
  • The Mallampati score (I-IV) predicts laryngoscopic difficulty from pharyngeal visualization; III-IV warns to ready rescue airway equipment
  • The TMC exam (160 questions, 3 hours, 140 scored) tests recognition of distress versus failure as a clinical-judgment skill, not just anatomy recall
Last updated: June 2026

Airway Anatomy & Assessment

A precise mental map of the airway is the foundation of every airway-management and oxygenation decision the respiratory therapist (RT) makes. The Therapist Multiple-Choice (TMC) Examination from the National Board for Respiratory Care (NBRC) — 160 items, 3 hours, 140 scored — repeatedly tests anatomy not as trivia but as the reasoning behind tube placement, suction depth, aspiration risk, and the urgent recognition of failing patients.

Upper Airway: The Conditioning Zone

The upper airway extends from the nose and mouth to the larynx and warms, filters, and humidifies inspired gas, delivering it to the carina at roughly 37 degrees C and 44 mg/L absolute humidity.

StructureKey featureClinical significance
Nasal cavityTurbinates warm/humidify; mucosa traps particlesNasal intubation route; epistaxis risk
OropharynxBehind the mouth; base of tongueMost common obstruction site when unconscious
EpiglottisLeaf-shaped cartilage covering the glottis when swallowingEpiglottitis is an airway emergency
LarynxHouses vocal cords; thyroid and cricoid cartilagesCricothyrotomy landmark; phonation
GlottisSpace between the true vocal cordsNarrowest point of the adult airway
Cricoid cartilageOnly complete 360-degree ringNarrowest point of the pediatric airway (<~8 yr)

Lower Airway: The Conducting & Gas-Exchange Zone

The lower airway begins at the trachea (10-12 cm, C-shaped rings open posteriorly) and branches at the carina into the mainstem bronchi.

StructureKey featureClinical significance
CarinaBifurcation, ~T4-T5 / 2nd ribEndotracheal tube (ETT) tip should sit 3-5 cm above it
Right mainstemShorter, wider, ~25-degree angleFavored target for aspiration and right-mainstem intubation
Left mainstemLonger, narrower, ~45-degree angleLess common aspiration/intubation site
BronchiolesNo cartilage; smooth muscleSite of bronchospasm in asthma and COPD
Alveoli~300 million; Type I gas exchange, Type II surfactantFinal gas-exchange surface

Worked trap: An intubated patient suddenly loses left-sided breath sounds with a rising peak pressure. Because the right mainstem is more vertical, the ETT has most likely migrated into the right mainstem. The fix is to deflate the cuff, withdraw the tube 1-2 cm, re-auscultate for bilateral sounds, re-inflate, and confirm by chest X-ray (tip 3-5 cm above the carina).

Distress Versus Impending Failure

The single most tested clinical judgment here is separating a compensating patient (distress) from a decompensating one (impending failure). Distress can often be managed with oxygen, bronchodilators, or noninvasive ventilation; impending failure demands an advanced airway.

Respiratory distress — the patient is still working effectively:

  • Tachypnea (respiratory rate > 20/min in adults)
  • Accessory muscle use (sternocleidomastoid, scalenes, intercostals)
  • Nasal flaring; intercostal and suprasternal retractions
  • Diaphoresis, agitation, inability to speak full sentences
  • Tripod positioning (upright, leaning forward, arms braced)

Impending respiratory failure — the patient is losing the battle:

  • Altered mental status (confusion, somnolence, unresponsiveness)
  • Paradoxical (abdominal) breathing — abdomen sinks as the chest rises
  • Bradycardia and a falling respiratory rate (ominous late signs)
  • Central cyanosis of lips and mucous membranes
  • Silent chest — no air movement despite visible effort

A classic exam scenario: a severe asthmatic who was loudly wheezing now has a quiet chest, a normalizing (no longer low) PaCO2, and is drowsy. This is not improvement — it is exhaustion and impending failure, and the answer is to prepare for intubation, not to celebrate.

Mallampati Classification

The Mallampati score predicts laryngoscopic difficulty from how much pharyngeal anatomy is visible with the mouth wide open and tongue protruded.

ClassWhat is visibleExpected difficulty
ISoft palate, fauces, full uvula, pillarsEasy
IISoft palate, fauces, uvulaUsually straightforward
IIISoft palate, base of uvulaPotentially difficult
IVHard palate onlyDifficult — ready rescue equipment

Mallampati is one of several difficult-airway predictors. Others worth recognizing include a thyromental distance under three fingerbreadths (a short, recessed chin), limited mouth opening under three fingerbreadths between the incisors, restricted neck extension, a large tongue or short muscular neck, and obstructive pathology such as airway burns, angioedema, or an expanding hematoma. A high Mallampati class is a flag, not a verdict: it tells the team to optimize positioning, have a video laryngoscope and a supraglottic rescue airway at the bedside, and avoid eliminating spontaneous ventilation until the airway is secured.

Positioning and Pediatric Differences

Proper positioning aligns the oral, pharyngeal, and laryngeal axes. In an adult, the sniffing position — neck flexed on the body with the head extended at the atlanto-occipital joint, often with a pad under the occiput — gives the best laryngoscopic view.

The pediatric airway differs in ways that change technique: the occiput is large (so a shoulder roll, not a head pad, achieves neutral alignment in infants), the tongue is proportionally larger, the larynx sits higher and more anterior (about C3-C4 versus C5-C6 in adults), the epiglottis is longer and floppier (favoring a straight Miller blade), and the cricoid ring is the narrowest point rather than the glottis. These differences explain why pediatric airway obstruction develops quickly and why even small amounts of edema or a slightly oversized tube cause disproportionate airway narrowing in a child.

Putting Assessment Together

Clinical assessment is a continuous loop, not a single snapshot. The RT integrates inspection (work of breathing, color, position, mentation), auscultation (air movement, adventitious sounds, symmetry), vital-sign trends, pulse oximetry, and — when available — arterial blood gases. A patient whose SpO2 holds but whose PaCO2 is climbing while alertness fades is heading toward ventilatory failure even with a 'normal' oxygen number, a pattern the exam uses to test whether you understand that oxygenation and ventilation are separate problems.

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Lower Airway Branching Structure
Test Your Knowledge

A patient is found unresponsive. What is the MOST common cause of upper airway obstruction?

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D
Test Your Knowledge

The right mainstem bronchus is the most common site for aspiration because it is:

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B
C
D
Test Your Knowledge

An exhausted asthmatic who was loudly wheezing now has a quiet chest, a PaCO2 that has risen from 30 to 44 mmHg, and is becoming drowsy. This combination indicates:

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B
C
D
Test Your Knowledge

Which finding is a sign of impending respiratory FAILURE rather than compensated distress?

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B
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D
Test Your KnowledgeFill in the Blank

The _____ cartilage is the only complete cartilage ring in the airway and serves as a landmark for cricothyrotomy.

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