200+ Free PANRE Practice Questions
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Key Facts: PANRE Exam
240
Total Questions
NCCPA
4h
Exam Time
NCCPA
379+
Passing Score
Scaled scoring
90-95%
Pass Rate
First-time takers
$350
Exam Fee
NCCPA 2026
10 years
Recertification Cycle
NCCPA
The PANRE is a 240-question exam administered over 4 hours with a passing score of 379+ on a scaled scoring system. First-time pass rates are approximately 90-95% for well-prepared candidates. The exam covers 14 organ system categories weighted by prevalence in clinical practice. PAs must pass PANRE every 10 years (or complete the PANRE Longitudinal Assessment) to maintain NCCPA certification.
About the PANRE Exam
The PANRE is a recertification examination for certified Physician Assistants. It assesses clinical knowledge and skills across all organ systems with content based on the NCCPA Content Blueprint: Cardiovascular (12%), Pulmonary (10%), GI/Nutrition (10%), EENT (8%), Endocrine (8%), Musculoskeletal (8%), Psychiatry (7%), Infectious Disease (7%), Reproductive (5%), Dermatology (5%), Genitourinary (5%), Neurology (5%), Hematology (4%), Renal (4%), and Emergent Topics (2%).
Questions
240 scored questions
Time Limit
4 hours
Passing Score
379+ (scaled)
Exam Fee
$350 (NCCPA (National Commission on Certification of Physician Assistants))
PANRE Exam Content Outline
Cardiovascular
Coronary artery disease, heart failure, arrhythmias, hypertension, valvular disease, peripheral vascular disease
Pulmonary
COPD, asthma, pneumonia, pulmonary embolism, lung cancer, sleep apnea
GI/Nutrition
GERD, PUD, IBD, liver disease, pancreatitis, gallbladder disease, nutritional deficiencies
EENT
Otitis media/externa, sinusitis, pharyngitis, conjunctivitis, vision/hearing loss, oral diseases
Endocrine
Diabetes mellitus, thyroid disorders, adrenal disorders, osteoporosis, metabolic syndrome
Musculoskeletal
Osteoarthritis, rheumatoid arthritis, gout, low back pain, fractures, sprains/strains
Psychiatry
Depression, anxiety disorders, bipolar disorder, schizophrenia, substance use disorders, PTSD
Infectious Disease
HIV/AIDS, hepatitis, TB, sepsis, meningitis, pneumonia, tick-borne diseases, endocarditis
Reproductive
Contraception, STIs, pregnancy complications, menopause, infertility, sexual dysfunction
Dermatology
Acne, eczema, psoriasis, skin cancer, dermatitis, skin infections, wound care
Genitourinary
UTIs, renal failure, kidney stones, BPH, erectile dysfunction, incontinence
Neurology
Stroke, seizures, headaches, dementia, multiple sclerosis, Parkinson disease, neuropathy
Hematology
Anemia, coagulation disorders, DVT/PE, leukemia, lymphoma, blood transfusion
Renal
Acute kidney injury, chronic kidney disease, electrolyte disorders, acid-base imbalance
Emergent Topics
Emergency care principles, legal/ethical issues, professional practice, patient safety
How to Pass the PANRE Exam
What You Need to Know
- Passing score: 379+ (scaled)
- Exam length: 240 questions
- Time limit: 4 hours
- Exam fee: $350
Keys to Passing
- Complete 500+ practice questions
- Score 80%+ consistently before scheduling
- Focus on highest-weighted sections
- Use our AI tutor for tough concepts
PANRE Study Tips from Top Performers
Frequently Asked Questions
What is the PANRE pass rate?
The PANRE first-time pass rate is approximately 90-95% for well-prepared candidates who have maintained their medical knowledge through clinical practice and continuing education. Pass rates may vary based on years of clinical experience and preparation.
How many questions are on the PANRE?
The PANRE contains 240 multiple-choice questions administered over 4 hours in four blocks of 60 questions each. The exam uses a scaled scoring system with a passing score of 379 or higher.
What is the PANRE content blueprint?
The NCCPA PANRE Content Blueprint includes 14 organ system categories: Cardiovascular (12%), Pulmonary (10%), GI/Nutrition (10%), EENT (8%), Endocrine (8%), Musculoskeletal (8%), Psychiatry (7%), Infectious Disease (7%), Reproductive (5%), Dermatology (5%), Genitourinary (5%), Neurology (5%), Hematology (4%), Renal (4%), and Emergent Topics including Professional Practice (2%).
When should I take PANRE?
Certified PAs must pass PANRE every 10 years. You can take it in the 5th or 6th year of your certification maintenance cycle, or in the 9th or 10th year. Alternatively, you may participate in the PANRE Longitudinal Assessment, which allows you to answer questions over time rather than in a single exam session.
What is the PANRE Longitudinal Assessment?
The PANRE Longitudinal Assessment is an alternative to the traditional PANRE exam. It allows PAs to answer 25 questions per quarter over 12 quarters (3 years). You can use references and have 5 minutes per question. Passing 8 of 12 quarters meets the certification requirement. This option is available starting in the 7th year of your certification cycle.
How should I prepare for PANRE?
Preparation should include: 1) Reviewing the NCCPA Content Blueprint to understand category weights, 2) Using practice questions covering all organ systems, 3) Focusing on high-weight categories (Cardiovascular, Pulmonary, GI), 4) Reviewing pharmacology and first-line treatments, 5) Studying screening guidelines and preventive care, 6) Completing at least 200 practice questions with detailed rationales.