1.3 General Exam Areas (GEAs) & Passing Standards

Key Takeaways

  • NPLEX Part I is evaluated across two distinct General Exam Areas: GEA 1 (Structure & Function) and GEA 2 (Disease & Dysfunction).
  • NABNE publishes no predetermined percentage or scaled score; administration-specific Angoff cut scores apply to both GEAs.
  • Failing a single GEA results in an overall fail for NPLEX Part I; NABNE requires candidates who fail either GEA to retake the entire 200-item examination at a subsequent administration.
  • Candidates must demonstrate competence in both GEAs during one administration; a failed GEA requires retaking the entire examination.
Last updated: August 2026

1.3 General Exam Areas (GEAs) & Passing Standards

NPLEX Part I has two General Exam Areas (GEAs), and a candidate must demonstrate competence in both during the same administration.

GEAIncluded SEAsApproximate exam share
Structure/FunctionAnatomy; Physiology; Biochemistry & Genetics60%
Disease/DysfunctionMicrobiology & Immunology; Pathology40%

The current guide also says the examination contains approximately 40 questions from each of the five Specific Exam Areas (SEAs). The 60/40 split therefore describes the two GEA groupings; it is not an Anatomy-versus-Embryology split and does not support the former unequal 20%/24%/16% discipline weights.

No Fixed 75 or Predetermined Percentage

NPLEX explicitly states that there is no predetermined passing score. It does not publish a fixed raw percentage, a fixed scaled score of 75, or a grading curve.

After each administration:

  1. A psychometrician performs post-test analysis.
  2. Subject-matter experts review any problematic items.
  3. A panel applies the Angoff method, estimating how a minimally competent candidate would perform on each item.
  4. Those judgments establish the cut score for that examination.
  5. Because forms differ in difficulty, the cut score can vary somewhat between administrations.

A harder form can therefore have a lower raw cut score than an easier form. This is criterion-referenced professional licensing standard setting, not ranking candidates against one another.

Both GEAs Must Pass

A candidate must earn the minimum cumulative score in Structure/Function and separately in Disease/Dysfunction. Strong performance in one GEA does not compensate for missing the cut score in the other.

If either GEA is below its administration-specific cut score:

  • the overall Part I result is a fail;
  • the passing GEA is not banked;
  • the candidate must retake the complete 200-question examination under the current NABNE reexamination rules.

Because the actual cut scores are established after the administration, a practice target should be a safety margin, not a claim that 70%, 75%, or another number guarantees a pass.

Score Timing and Study Use

The blueprint says post-test analysis and standard setting take approximately seven weeks before scores are released to NABNE. Consult the current handbook and candidate account for the exact release and reporting process for your administration.

Use the GEA structure diagnostically:

  • weak Anatomy, Physiology, or Biochemistry & Genetics performance threatens Structure/Function;
  • weak Microbiology & Immunology or Pathology performance threatens Disease/Dysfunction;
  • the 11 system percentages help locate where those sciences are applied.

The safest plan is balanced competence across all five SEAs and all 11 systems, with extra remediation in the weaker GEA.

Test Your Knowledge

Which disciplines are combined to form General Exam Area 1 (GEA 1: Structure & Function)?

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Test Your Knowledge

How does NPLEX establish the passing standard for each Part I administration?

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Test Your Knowledge

What happens if a candidate meets the cut score for Structure/Function but not Disease/Dysfunction?

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D