Free NPLEX I Exam Prep
NPLEX Part I — Biomedical Sciences
Prepare for the NPLEX I exam without spending hundreds on expensive prep courses. Free study guides, practice questions, flashcards, and related exam resources.
Quick Facts
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NPLEX NPLEX Naturopathic Licensing Exams License: Complete Roadmap
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Anatomy and HistologyYou are here
Master gross anatomy by region, histology of all tissue types, neuroanatomy (cranial nerves, tracts, brainstem), and key embryological derivatives.
Physiology
Work through Guyton-level physiology of all organ systems: cardiovascular, respiratory, renal, GI, endocrine, reproductive, and neurophysiology. Integrate acid-base and fluid/electrolyte balance.
Biochemistry and Genetics
Review metabolic pathways (glycolysis, TCA, electron transport, fatty acid oxidation, urea cycle), enzyme kinetics, vitamins and minerals, and inherited metabolic disorders.
Microbiology and Immunology
Learn major bacterial, viral, fungal, and parasitic pathogens by system, plus innate vs adaptive immunity, antibody classes, hypersensitivity reactions, and vaccine types.
Pathology
Cover general pathology (inflammation, cell injury, neoplasia) and systems pathology using Robbins. Build differential diagnoses from morphology, histology, and lab findings.
Integration and Practice Exams
Complete full-length timed practice exams, review case-based questions, and drill weak areas identified in diagnostic testing.
Can You Take the NPLEX I Exam?
Check if you meet the basic eligibility requirements
- •Academic eligibility verification from an approved naturopathic medical program
- •Completion of the program's biomedical science coursework requirements
- •Graduates more than five years out must contact NABNE regarding additional eligibility requirements
- •Must be passed before sitting for NPLEX Part II
- •Government-issued photo ID at Prometric testing center
NPLEX I Quick Facts
Time to Get Licensed
NABNE does not publish a recommended study timeline
From start to license in hand
Retake Policy
A candidate who does not pass either GEA must retake the entire Part I examination in a subsequent administration and complete the current re-examination process; NABNE publishes no fixed day-based wait.
Total Cost Breakdown
Free NPLEX I Prep Tools
Reported exam pass rate: Not published by NABNE. These figures describe exam candidates, not OpenExamPrep user outcomes. Check the exam sponsor’s website for published statistics.
112+ Practice Questions
Practice by topic with detailed answer explanations
AI Tutor Explains Mistakes
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Independent Study Resources
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What You'll Study
15 chapters covering the exam topics in this guide
Chapter 1: Exam Structure, Pacing, and GEA Strategy
3 sections
Chapter 2: Gross Anatomy & Musculoskeletal System
3 sections
Chapter 3: Histology & Microscopic Anatomy
3 sections
Chapter 4: Neuroanatomy & Special Senses
4 sections
Chapter 5: Embryology & Developmental Anatomy
3 sections
Chapter 6: Cellular & General Physiology
3 sections
Chapter 7: Cardiovascular & Respiratory Physiology
4 sections
Chapter 8: Renal, Fluid, & Acid-Base Physiology
4 sections
Chapter 9: Gastrointestinal, Endocrine, & Reproductive Physiology
4 sections
Chapter 10: Enzymology, Bioenergetics, & Carbohydrate/Lipid Metabolism
4 sections
Chapter 11: Amino Acid/Nucleotide Metabolism & Clinical Genetics
3 sections
Chapter 12: Immunology & Immunopathology
4 sections
Chapter 13: Medical Microbiology
4 sections
Chapter 14: General Pathology & Neoplasia
3 sections
Chapter 15: Systems Pathology & Disease Mechanisms
8 sections
NPLEX I Exam Details
NPLEX Part I — Biomedical Sciences
Administered by NABNE (North American Board of Naturopathic Examiners)
Exam Content Breakdown
Based on the official NABNE (North American Board of Naturopathic Examiners) content outline
Structure, function, biochemistry and genetics, microbiology and immunology, and pathology of the cardiovascular system
Biomedical sciences of endocrine organs, hormone regulation, and endocrine disease
Biomedical sciences of the gastrointestinal tract, liver, pancreas, and related disease
Hematopoiesis, blood-cell disorders, hemostasis, neoplasms, and blood-borne infection
Lymphoid structure and function, immune mechanisms, hypersensitivity, autoimmunity, and immunodeficiency
Skin structure and function plus inflammatory, infectious, autoimmune, and neoplastic disease
Bone, joint, and muscle biomedical sciences and associated disorders
Central and peripheral nervous-system structure, physiology, biochemistry, infection, and pathology
Respiratory anatomy, physiology, gas exchange, host defense, and disease
Female and male reproductive development, physiology, genetics, infection, and pathology
Renal and urinary structure, physiology, acid-base regulation, infection, and pathology
What's Included
15 Chapters
Complete exam coverage
Practice Quizzes
With detailed explanations
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What's Next After the NPLEX I?
After passing the NPLEX I, you can pursue these career paths
NPLEX Part II — Core Clinical Sciences
The core clinical-science examination that follows Part I; licensing authorities determine their own licensure requirements
NPLEX Part II — Clinical Electives
Optional clinical elective modules (minor surgery, acupuncture, pharmacology) required by some jurisdictions
NPLEX I Exam FAQ
Official NABNE (North American Board of Naturopathic Examiners) Resources
Verify information with these official sources
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