13.2 ECMO & LVAD Overview for the Cath Lab
Key Takeaways
- VA ECMO drains deoxygenated blood from a large venous cannula, oxygenates it through a membrane lung, and returns it via an arterial cannula — providing both circulatory and respiratory support in refractory cardiogenic shock.
- Femoral VA ECMO carries limb ischemia risk; a distal perfusion catheter and contralateral limb pulse monitoring are essential cath lab responsibilities during cannulation support.
- Continuous-flow LVADs produce minimal arterial pulsatility, requiring Doppler blood pressure measurement and reliance on console parameters — speed, flow, power, and pulsatility index — rather than traditional pulse pressure.
- Rising LVAD power with falling flow suggests pump thrombosis or outflow obstruction and requires immediate notification of the VAD coordinator.
- Mechanical support escalation in the cath lab typically progresses from IABP to Impella to VA ECMO to durable LVAD or transplant based on the severity and reversibility of hemodynamic failure.
Advanced Mechanical Support Beyond the Balloon Pump
When counterpulsation and Impella support are insufficient, the cath lab team may encounter extracorporeal membrane oxygenation (ECMO) and patients with implanted left ventricular assist devices (LVADs). Domain C Task 7 expects the RCIS technologist to understand how these systems function, what role the cath lab plays during insertion or management, and the safety rules that differ from standard catheterization. You are not expected to manage an LVAD program independently, but you must recognize device types, interpret console parameters, and avoid actions that harm supported patients.
Extracorporeal Membrane Oxygenation (ECMO)
ECMO is a temporary extracorporeal circuit that provides gas exchange and/or circulatory support outside the body. Blood drains through a large cannula, passes through a centrifugal pump and membrane oxygenator (artificial lung), and returns to the patient through an outflow cannula. The cath lab most commonly sees veno-arterial (VA) ECMO in refractory cardiogenic shock, post-cardiac arrest, or as a bridge during high-risk interventions.
VA ECMO Versus VV ECMO
| Configuration | Blood Inflow | Blood Outflow | Primary Purpose |
|---|---|---|---|
| VA ECMO | Large vein (femoral, internal jugular) | Artery (femoral, axillary, carotid) | Cardiac and respiratory support |
| VV ECMO | Vein (femoral, IJ) | Vein (return to right atrium) | Respiratory support only; native heart must pump |
VA ECMO bypasses both the lungs and a failing heart: deoxygenated blood is drained from the venous system, oxygenated through the membrane lung, and returned under pressure into the arterial system. This provides forward flow and oxygen delivery when the native heart cannot maintain adequate perfusion. Flow rates typically range from 3–6 L/min depending on patient size and cannula diameter.
VV ECMO supports gas exchange in severe ARDS while the heart continues to pump; it is less common in the cardiac cath lab but may appear in hybrid cardiovascular-critical care settings.
VA ECMO Cannulation and Cath Lab Role
Percutaneous femoral veno-arterial cannulation is the most frequent emergent configuration the RCIS team supports. A large-bore venous cannula (commonly 21–25 Fr) is advanced into the inferior vena cava or right atrium for drainage. An arterial outflow cannula (15–19 Fr or larger) is placed in the common femoral artery (or axillary artery when limb perfusion is a concern).
The RCIS assists with:
- Ultrasound-guided vascular access for large-bore cannulae
- Fluoroscopic confirmation of wire and cannula position
- Anticoagulation management — ECMO requires systemic heparinization; activated clotting time (ACT) targets are typically 180–220 seconds per institutional protocol
- Hemodynamic monitoring — arterial line, central venous pressure, and pulse oximetry on both the supported limb and a contralateral limb
- Distal perfusion catheter placement when femoral arterial cannulation risks limb ischemia
Hemodynamics and the "Harlequin" Phenomenon
During VA ECMO, the native heart may eject minimally or not at all. The arterial line may show a flat or dampened waveform because forward flow comes primarily from the ECMO pump, not ventricular contraction. Upper-body hypoxia can occur with femoral VA ECMO when the native heart recovers enough to eject deoxygenated blood from the lungs while ECMO-supplied oxygenated blood enters the lower body — the Harlequin (North-South) syndrome. Recognizing this pattern requires communication with the ECMO specialist and may prompt conversion to central cannulation or addition of an upper-body outflow cannula.
ECMO Complications Relevant to the Cath Lab
| Complication | Presentation | RCIS Response |
|---|---|---|
| Limb ischemia | Cool, pale, pulseless distal extremity on cannulated side | Notify team; confirm distal perfusion catheter function |
| Bleeding | Access site oozing, falling hematocrit, hemothorax | Maintain ACT per protocol; prepare blood products |
| Hemolysis | Dark plasma, rising LDH, anemia | Check cannula position and pump speed |
| Clotting in circuit | Rising pressures across oxygenator | Alert perfusion/ECMO team; do not independently adjust pump |
| Air embolism | Sudden hemodynamic collapse during line manipulation | Clamp circuit; notify perfusion immediately |
The RCIS does not independently titrate ECMO flow or sweep gas — those are perfusionist or ECMO specialist responsibilities. Your role is access support, monitoring, anticoagulation sample coordination, and rapid escalation when complications arise.
Left Ventricular Assist Devices (LVAD): Cath Lab Essentials
An LVAD is a durable or destination-therapy pump surgically implanted to support the failing left ventricle. Common platforms include HeartMate 3 (Abbott) and historically HeartWare HVAD (Medtronic). These are continuous-flow centrifugal pumps that draw blood from the LV apex through an inflow cannula and eject it into the ascending aorta through an outflow graft, bypassing the native ventricular outflow tract.
Unlike IABP or Impella, LVADs are long-term implants — patients may present to the cath lab months or years after implantation for coronary angiography, PCI, right heart catheterization, or device malfunction evaluation.
LVAD Physiology: What Looks Different
Continuous-flow LVADs produce non-pulsatile or minimally pulsatile arterial waveforms. Key implications for the cath lab:
- Blood pressure may be measured with a Doppler probe over the brachial or radial artery (reported as MAP in mmHg) because a standard cuff may not detect a pulse.
- Pulse oximetry may be unreliable on the same extremity used for Doppler BP; use alternative sites.
- Cardiac output is not calculated from traditional pulse pressure methods — rely on LVAD console parameters: speed (RPM), estimated flow (L/min), power (watts), and pulsatility index (PI).
| Console Parameter | Normal Trend | Alarm Significance |
|---|---|---|
| Speed (RPM) | Set by VAD team (e.g., 5200–5800 for HeartMate 3) | Sudden drops suggest power failure or controller issue |
| Flow (L/min) | 4–6 L/min typical at rest | Low flow with high power → inflow or outflow obstruction |
| Power (watts) | Stable baseline for a given speed | Rising power with falling flow suggests pump thrombosis |
| Pulsatility index (PI) | Reflects native LV contractility | Very low PI may indicate hypovolemia, arrhythmia, or tamponade |
LVAD-Specific Cath Lab Safety Rules
Chest compressions during cardiac arrest in patients with an implanted continuous-flow LVAD are controversial and institution-specific — some protocols permit modified compressions while others prioritize maintaining pump power and treating arrhythmias. Know your hospital's policy. Never disconnect the driveline or power source without the VAD coordinator present.
Right heart catheterization in LVAD patients requires careful wire and catheter manipulation to avoid entanglement with the inflow cannula at the LV apex. Coronary angiography is performed with attention to hemodynamic tolerance — reduce contrast load when possible and maintain MAP per VAD team orders.
Anticoagulation is mandatory: most LVAD patients are on warfarin (INR target typically 2.0–3.0 for HeartMate 3) plus antiplatelet therapy. Coordinate heparin during PCI with the VAD team to avoid supratherapeutic bleeding.
LVAD Alarms the RCIS Should Recognize
- Low flow alarm: Assess volume status, check for tamponade (bedside echo if available), verify speed settings, rule out kinked outflow graft.
- High power alarm: Suggests pump thrombus or outflow obstruction — notify the VAD coordinator and operator immediately; may require urgent device exchange or thrombolysis per protocol.
- Controller fault / battery depletion: Switch to backup batteries or hand pump immediately; never leave the patient without a power source.
Document all console parameters at baseline, after any hemodynamic change, and at case conclusion. The VAD coordinator or heart failure service should be present or immediately available for any invasive procedure on an LVAD patient.
Putting It Together: Escalation Pathway
The cath lab mechanical support ladder typically progresses as follows:
- Pharmacologic support — inotropes, vasopressors
- IABP — counterpulsation for moderate hemodynamic compromise
- Impella — active LV unloading when greater flow is needed
- VA ECMO — biventricular and respiratory failure
- Durable LVAD or transplant — long-term or destination therapy
The RCIS technologist supports each transition with appropriate access, monitoring, anticoagulation coordination, and device-specific safety knowledge. On the RCIS exam, expect overview-level questions on VA ECMO cannulation configuration, limb ischemia prevention, continuous-flow LVAD physiology, and which parameters indicate pump thrombosis — not independent ECMO or VAD programming.
What is the primary difference between veno-arterial (VA) ECMO and veno-venous (VV) ECMO?
A patient with a HeartMate 3 LVAD presents for coronary angiography. The arterial line shows a flat waveform and the cuff blood pressure reads error. What is the most appropriate blood pressure measurement technique?
During VA ECMO support via femoral arterial cannulation, the patient's right foot becomes cool and pulseless while the left foot remains warm with palpable pulses. What is the most likely cause and immediate concern?