299+ Free MO MPJE Practice Questions

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Question 1

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Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?

Schedule I

Schedule II

Schedule III

Schedule IV

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Free MPJE Practice Test by State 2026: 5,000+ Pharmacy Law Questions18 min read

2026 Statistics

Key Facts: MO MPJE Exam

120

Questions

100 scored + 20 pretest

Passing Score

NABP scaled score

2.5h

Exam Time

Pearson VUE

3:1

Tech Ratio

MO max

30h/2yr

CE Required

MO renewal

$250

Exam Fee

NABP 2026

The MO MPJE covers federal pharmacy law (DEA, FDA, CSA, HIPAA) and Missouri-specific regulations including PDMP mandatory checks, naloxone standing order, collaborative practice agreements, opioid prescribing limits, 30h/2yr CE, and 3:1 technician ratio.

Sample MO MPJE Practice Questions

Try these sample questions to test your MO MPJE exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 299+ question experience with AI tutoring.

1Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?

A.Schedule I

B.Schedule II

C.Schedule III

D.Schedule IV

Explanation: Schedule I substances have a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision. Examples include heroin, LSD, and MDMA. Pharmacists cannot dispense Schedule I substances under normal practice.

2A DEA Form 222 is required for the transfer of which schedule of controlled substances between registrants?

A.Schedule II only

B.Schedules II and III

C.Schedules III through V

D.All controlled substances

Explanation: DEA Form 222 (or its electronic equivalent under CSOS) is required for the distribution and transfer of Schedule II controlled substances between DEA registrants. Schedules III-V can be transferred using invoices with specific record-keeping requirements.

3Under federal law, what is the maximum number of refills allowed for a Schedule III controlled substance prescription?

A.No refills allowed

B.Up to 3 refills within 6 months

C.Up to 5 refills within 6 months

D.Up to 5 refills within 1 year

Explanation: Federal law allows up to 5 refills for Schedule III-V controlled substance prescriptions within 6 months from the date the prescription was issued. Schedule II prescriptions cannot be refilled.

4The Durham-Humphrey Amendment of 1951 established which key distinction in drug classification?

A.Generic vs. brand-name drugs

B.Prescription (legend) vs. over-the-counter drugs

C.Controlled vs. non-controlled substances

D.Biological vs. chemical drugs

Explanation: The Durham-Humphrey Amendment to the Federal Food, Drug, and Cosmetic Act established the distinction between prescription (legend) drugs and over-the-counter (OTC) drugs, requiring certain drugs to bear the legend 'Caution: Federal law prohibits dispensing without prescription.'

5Under HIPAA, which of the following is considered a permitted disclosure of protected health information (PHI) without patient authorization?

A.Sharing prescription data with a marketing company

B.Disclosing PHI for treatment, payment, or healthcare operations

C.Posting patient medication lists on social media for educational purposes

D.Providing medication history to a patient's employer upon request

Explanation: HIPAA permits disclosure of PHI without patient authorization for treatment, payment, and healthcare operations (TPO). All other disclosures generally require written patient authorization unless specifically exempted by law.

6The Poison Prevention Packaging Act (PPPA) requires child-resistant containers for most prescription drugs. Which of the following is exempt from this requirement?

A.Oral contraceptives dispensed in manufacturer's compliance packaging

B.All Schedule II controlled substances

C.Any medication for patients over age 50

D.Antibiotics in liquid form

Explanation: Oral contraceptives in manufacturer's mnemonic (compliance) packaging are exempt from PPPA child-resistant packaging requirements. Other exemptions include sublingual nitroglycerin, certain corticosteroid inhalers, and situations where the prescriber or patient requests non-child-resistant packaging.

7Under the Combat Methamphetamine Epidemic Act (CMEA), pseudoephedrine sales are limited to what maximum quantity per 30-day period?

A.3.6 grams

B.7.5 grams

C.9 grams

D.15 grams

Explanation: The CMEA limits pseudoephedrine purchases to 9 grams per 30-day period and 3.6 grams per day. Products must be kept behind the counter or in locked cabinets, and purchasers must present identification and sign a logbook.

8Under OBRA '90, pharmacists are required to perform which of the following for Medicaid patients?

A.Free medication delivery

B.Drug utilization review (DUR) and patient counseling

C.Annual physical examinations

D.Genetic testing before dispensing

Explanation: OBRA '90 (Omnibus Budget Reconciliation Act of 1990) requires pharmacists to conduct prospective drug utilization review (DUR) and offer counseling to Medicaid patients on new prescriptions. Most states have extended this requirement to all patients.

9The FDA's Risk Evaluation and Mitigation Strategies (REMS) program may require which of the following?

A.Mandatory genetic testing for all patients

B.Medication guides, communication plans, or elements to assure safe use (ETASU)

C.Automatic substitution with generic equivalents

D.Prior authorization from the DEA before dispensing

Explanation: REMS may include medication guides, communication plans, and Elements to Assure Safe Use (ETASU) such as prescriber certification, patient registries, or restricted distribution systems. iPLEDGE for isotretinoin is a well-known example of a REMS with ETASU.

10Under the Drug Supply Chain Security Act (DSCSA), pharmacies must maintain transaction records for prescription drugs for how long?

A.1 year

B.3 years

C.6 years

D.10 years

Explanation: The DSCSA requires trading partners, including pharmacies, to maintain transaction information (TI), transaction history (TH), and transaction statements (TS) for at least 6 years to ensure drug supply chain integrity and enable tracing of suspect or illegitimate products.

About the MO MPJE Exam

The Missouri MPJE tests knowledge of federal pharmacy law and Missouri-specific pharmacy regulations under RSMo Chapter 338. Required alongside the NAPLEX for pharmacist licensure in Missouri.

Questions

120 scored questions

Time Limit

2.5 hours

Passing Score

75 (scaled score)

Exam Fee

$250 (NABP / MO Board of Pharmacy)

MO MPJE Exam Content Outline

22%

Licensure & Personnel

Pharmacist qualifications, intern/technician requirements, license renewal, disciplinary actions

33%

Pharmacist Practice

Prescription requirements, counseling, controlled substance rules, collaborative practice agreements

24%

Dispensing Requirements

Generic substitution, prescription transfers, DUR, labeling, PDMP checking

21%

Pharmacy Operations

Controlled substance records, compounding standards, pharmacy permits, automated dispensing

How to Pass the MO MPJE Exam

What You Need to Know

Passing score: 75 (scaled score)
Exam length: 120 questions
Time limit: 2.5 hours
Exam fee: $250

Keys to Passing

Complete 500+ practice questions
Score 80%+ consistently before scheduling
Focus on highest-weighted sections
Use our AI tutor for tough concepts

MO MPJE Study Tips from Top Performers

1Study RSMo Chapter 338 and 20 CSR 2220 for Missouri-specific pharmacy regulations

2Master DEA controlled substance schedules, forms (222, 106, 41), and requirements

3Know Missouri PDMP requirements and mandatory checking protocols

4Review Missouri collaborative practice agreement authority and scope

5Understand federal vs. state law conflicts — the more restrictive law prevails

Frequently Asked Questions

What is the MO MPJE passing score?

The Missouri MPJE requires a scaled score of 75. The exam has 120 questions (100 scored, 20 pretest) over 2.5 hours at Pearson VUE.

What Missouri laws are tested?

The MO MPJE covers RSMo Chapter 338, Board of Pharmacy rules (20 CSR 2220), PDMP requirements, collaborative practice, and state-specific dispensing regulations.

What is the technician ratio in Missouri?

Missouri allows a 3:1 technician-to-pharmacist ratio. Technicians must be registered with the Board and work under direct pharmacist supervision.

How many CE hours does Missouri require?

Missouri requires 30h/2yr of continuing pharmacy education per renewal period, including 2 hours in pharmacy law.

Does Missouri allow collaborative practice agreements?

Yes, Missouri permits CPAs (RSMo §338.010) allowing pharmacists to manage drug therapy, order labs, and administer medications under written agreements with prescribers.