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Exam Review

Key Facts: MO MPJE Exam

120

Questions

100 scored + 20 pretest

75

Passing Score

NABP scaled score

2.5h

Exam Time

Pearson VUE

3:1

Tech Ratio

MO max

30h/2yr

CE Required

MO renewal

$250

Exam Fee

NABP 2026

The MO MPJE covers federal pharmacy law (DEA, FDA, CSA, HIPAA) and Missouri-specific regulations including PDMP mandatory checks, naloxone standing order, collaborative practice agreements, opioid prescribing limits, 30h/2yr CE, and 3:1 technician ratio.

Sample MO MPJE Practice Questions

Try these sample questions to review concepts for the MO MPJE exam. Each question includes a detailed explanation. Start the interactive quiz above for the full 319+ question experience with AI tutoring.

1Under the Controlled Substances Act (CSA), which DEA schedule includes drugs with the highest potential for abuse and no currently accepted medical use?
A.Schedule I
B.Schedule II
C.Schedule III
D.Schedule IV
Explanation: Schedule I substances have a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision. Examples include heroin, LSD, and MDMA. Pharmacists cannot dispense Schedule I substances under normal practice.
2A DEA Form 222 is required for the transfer of which schedule of controlled substances between registrants?
A.Schedule II only
B.Schedules II and III
C.Schedules III through V
D.All controlled substances
Explanation: DEA Form 222 (or its electronic equivalent under CSOS) is required for the distribution and transfer of Schedule II controlled substances between DEA registrants. Schedules III-V can be transferred using invoices with specific record-keeping requirements.
3Under federal law, what is the maximum number of refills allowed for a Schedule III controlled substance prescription?
A.No refills allowed
B.Up to 3 refills within 6 months
C.Up to 5 refills within 6 months
D.Up to 5 refills within 1 year
Explanation: Federal law allows up to 5 refills for Schedule III-V controlled substance prescriptions within 6 months from the date the prescription was issued. Schedule II prescriptions cannot be refilled.
4The Durham-Humphrey Amendment of 1951 established which key distinction in drug classification?
A.Generic vs. brand-name drugs
B.Prescription (legend) vs. over-the-counter drugs
C.Prescription drugs versus controlled substances classified in Schedules II through V
D.Biological vs. chemical drugs
Explanation: The Durham-Humphrey Amendment to the Federal Food, Drug, and Cosmetic Act established the distinction between prescription (legend) drugs and over-the-counter (OTC) drugs, requiring certain drugs to bear the legend 'Caution: Federal law prohibits dispensing without prescription.'
5Under HIPAA, which of the following is considered a permitted disclosure of protected health information (PHI) without patient authorization?
A.Sharing prescription data with a marketing company
B.Disclosing PHI for treatment, payment, or healthcare operations
C.Posting patient medication lists on social media for educational purposes
D.Providing medication history to a patient's employer upon request
Explanation: HIPAA permits disclosure of PHI without patient authorization for treatment, payment, and healthcare operations (TPO). All other disclosures generally require written patient authorization unless specifically exempted by law.
6The Poison Prevention Packaging Act (PPPA) requires child-resistant containers for most prescription drugs. Which of the following is exempt from this requirement?
A.Oral contraceptives dispensed in manufacturer's compliance packaging
B.All Schedule II controlled substances
C.All prescription drugs repackaged by a pharmacy into ordinary noncompliance containers
D.Antibiotics in liquid form
Explanation: Oral contraceptives in manufacturer's mnemonic (compliance) packaging are exempt from PPPA child-resistant packaging requirements. Other exemptions include sublingual nitroglycerin, certain corticosteroid inhalers, and situations where the prescriber or patient requests non-child-resistant packaging.
7Under the federal Combat Methamphetamine Epidemic Act (CMEA), what is the maximum retail purchase amount of pseudoephedrine base per 30-day period?
A.3.6 grams
B.7.5 grams
C.9 grams
D.15 grams
Explanation: For retail purchases, the federal CMEA limits pseudoephedrine base to 9 grams per purchaser during a 30-day period and 3.6 grams per day. The separate federal 30-day limit for sales by a regulated seller through the mail or a private or commercial carrier is 7.5 grams. Applicable Missouri limits must also be checked.
8Under OBRA '90, pharmacists are required to perform which of the following for Medicaid patients?
A.Free medication delivery
B.Drug utilization review (DUR) and patient counseling
C.Annual physical examinations
D.A mandatory federal report of every dispensing error and near miss to the FDA
Explanation: OBRA '90 (Omnibus Budget Reconciliation Act of 1990) requires pharmacists to conduct prospective drug utilization review (DUR) and offer counseling to Medicaid patients on new prescriptions. Most states have extended this requirement to all patients.
9The FDA's Risk Evaluation and Mitigation Strategies (REMS) program may require which of the following?
A.Mandatory genetic testing for all patients
B.Medication guides, communication plans, or elements to assure safe use (ETASU)
C.Automatic substitution with generic equivalents
D.Mandatory recall, civil-penalty, and prescriber-discipline measures for every covered product
Explanation: REMS may include medication guides, communication plans, and Elements to Assure Safe Use (ETASU) such as prescriber certification, patient registries, or restricted distribution systems. iPLEDGE for isotretinoin is a well-known example of a REMS with ETASU.
10Under the DSCSA, how long must a dispenser retain the product-tracing documentation it receives for a covered prescription drug transaction?
A.1 year
B.3 years
C.6 years
D.10 years
Explanation: A dispenser must retain applicable DSCSA transaction information and transaction statements for at least six years after the transaction. Current enhanced tracing is electronic and interoperable; older references to a continuing transaction-history document should not be treated as the current data model.

About the MO MPJE Exam

The Missouri MPJE tests knowledge of federal pharmacy law and Missouri-specific pharmacy regulations under RSMo Chapter 338. Required alongside the NAPLEX for pharmacist licensure in Missouri.

Exam sponsor: NABP / MO Board of Pharmacy. The requirements and fees below concern the certification or admission exam, separate from our free practice resources.

Questions

120 questions

Time Limit

2.5 hours

Passing Score

75 (scaled score)

Exam / Certification Fees

$250

Exam sponsor website

Reported exam pass rate: Not publicly reported. Exam sponsor website

Fees, eligibility, and exam policies can change. Confirm them with the exam sponsor before applying or paying.

Our practice resources: topics covered

We aim to reflect publicly available exam outlines and topic information in our study resources. Coverage, format, and difficulty may differ from the actual exam, and we cannot guarantee that every detail is accurate or current. Confirm exam requirements, fees, and policies with the official exam sponsor.

22%

Licensure & Personnel

Pharmacist qualifications, intern/technician requirements, license renewal, disciplinary actions

33%

Pharmacist Practice

Prescription requirements, counseling, controlled substance rules, collaborative practice agreements

24%

Dispensing Requirements

Generic substitution, prescription transfers, DUR, labeling, PDMP checking

21%

Pharmacy Operations

Controlled substance records, compounding standards, pharmacy permits, automated dispensing

Preparing for the MO MPJE Exam

What You Need to Know

  • Passing score: 75 (scaled score)
  • Exam length: 120 questions
  • Time limit: 2.5 hours
  • Exam / certification fees: $250 Official sources

Using Our Practice Resources

  • Work through all 319 available questions
  • Review every answer and explanation
  • Track weak areas and revisit them
  • Use our AI tutor for tough concepts

MO MPJE: Suggested Study Strategy

1Study RSMo Chapter 338 and 20 CSR 2220 for Missouri-specific pharmacy regulations
2Master DEA controlled substance schedules, forms (222, 106, 41), and requirements
3Know Missouri PDMP requirements and mandatory checking protocols
4Review Missouri collaborative practice agreement authority and scope
5Understand federal vs. state law conflicts — the more restrictive law prevails

Frequently Asked Questions

What is the MO MPJE passing score?

The Missouri MPJE requires a scaled score of 75. The exam has 120 questions (100 scored, 20 pretest) over 2.5 hours at Pearson VUE.

What Missouri laws are tested?

The MO MPJE covers RSMo Chapter 338, Board of Pharmacy rules (20 CSR 2220), PDMP requirements, collaborative practice, and state-specific dispensing regulations.

What is the technician ratio in Missouri?

Missouri allows a 3:1 technician-to-pharmacist ratio. Technicians must be registered with the Board and work under direct pharmacist supervision.

How many CE hours does Missouri require?

Missouri requires 30h/2yr of continuing pharmacy education per renewal period, including 2 hours in pharmacy law.

Does Missouri allow collaborative practice agreements?

Yes, Missouri permits CPAs (RSMo §338.010) allowing pharmacists to manage drug therapy, order labs, and administer medications under written agreements with prescribers.