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100+ Free INI-SS Practice Questions

Pass your Institute of National Importance Super-Speciality Entrance Test (INI-SS) exam on the first try — instant access, no signup required.

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Key Facts: INI-SS Exam

80 questions

INI-SS Stage-I has 80 single-best-answer MCQs in 90 minutes (AIIMS)

AIIMS INI-SS Prospectus - Scheme of Examination

+1 / -1/3

Each correct answer scores +1 and each wrong answer loses 1/3 mark

AIIMS INI-SS Prospectus - Scheme of Examination

50% cutoff

Candidates need at least 40 of 80 marks to qualify Stage-I

AIIMS INI-SS Prospectus - Scheme of Examination

Twice a year

INI-SS is conducted by AIIMS New Delhi for the January and July sessions

AIIMS Assessment and Examination Portal

60% / 40%

About 60% of questions are feeder specialty and 40% super-speciality foundations

INI-SS exam pattern, feeder and super-speciality split

Rs. 4,000

INI-SS application fee plus transaction charges; PWBD candidates exempted

AIIMS INI-SS Prospectus - Application Fee

5 INIs

Seats span AIIMS, PGIMER, JIPMER, NIMHANS and SCTIMST plus newer AIIMS

AIIMS INI-SS seat matrix

100

Free original INI-SS practice questions available here

OpenExamPrep

INI-SS is AIIMS New Delhi's centralised super-speciality entrance test for DM and MCh seats at AIIMS, PGIMER, JIPMER, NIMHANS and SCTIMST, held twice a year. Stage-I is a 90-minute computer-based test of 80 single-best-answer MCQs, scored +1 for correct and -1/3 for wrong, with a 50% (40/80) qualifying cutoff. Questions blend the feeder MD/MS specialty fundamentals (about 60%) with super-speciality foundations such as cardiology, neurology, nephrology, gastroenterology, endocrinology and the surgical super-specialities (about 40%). The application fee is Rs. 4,000 plus transaction charges, with PWBD candidates exempted. This 100-question bank gives original single-best-answer practice across medicine and surgery super-speciality foundations and clinical reasoning.

Sample INI-SS Practice Questions

Try these sample questions to test your INI-SS exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1A 58-year-old man with crushing central chest pain has ST-segment elevation in leads II, III and aVF on ECG. Which coronary artery is most likely occluded?
A.Left anterior descending artery
B.Right coronary artery
C.Left circumflex artery
D.Left main coronary artery
Explanation: ST elevation in the inferior leads (II, III, aVF) indicates an inferior wall myocardial infarction, which in most people is supplied by the right coronary artery. RCA occlusion can also cause bradyarrhythmias and right ventricular involvement.
2Which valvular lesion classically produces a mid-diastolic rumbling murmur best heard at the apex with the patient in the left lateral position?
A.Aortic stenosis
B.Mitral stenosis
C.Mitral regurgitation
D.Aortic regurgitation
Explanation: Mitral stenosis produces a low-pitched mid-diastolic rumble at the apex, accentuated in the left lateral decubitus position and often preceded by an opening snap. Rheumatic heart disease is the commonest cause worldwide.
3In a patient with heart failure and reduced ejection fraction, which drug class reduces mortality primarily by blocking the neurohormonal effects of aldosterone?
A.Loop diuretics
B.Mineralocorticoid receptor antagonists
C.Calcium channel blockers
D.Digoxin
Explanation: Mineralocorticoid receptor antagonists such as spironolactone and eplerenone reduce mortality in HFrEF by blocking aldosterone-mediated fibrosis, sodium retention and potassium loss. They are part of guideline-directed quadruple therapy.
4A young woman has episodic palpitations with a narrow-complex tachycardia at 180/min that terminates abruptly with carotid sinus massage. The most likely mechanism is:
A.Atrioventricular nodal re-entry
B.Ventricular tachycardia
C.Atrial fibrillation
D.Sinus tachycardia
Explanation: AV nodal re-entrant tachycardia is the commonest regular paroxysmal supraventricular tachycardia in young patients and depends on the AV node, so vagal manoeuvres or carotid massage that slow AV conduction can terminate it abruptly.
5Which biomarker rises within 3-4 hours of myocardial injury, peaks early and is most useful for diagnosing reinfarction because it normalises within 24-48 hours?
A.Troponin T
B.CK-MB
C.Lactate dehydrogenase
D.Myoglobin
Explanation: CK-MB rises within hours and returns to normal within 24-48 hours, so a renewed rise is useful to detect early reinfarction. Troponins stay elevated for many days and are less helpful for this specific purpose.
6A 24-year-old man collapses during exercise. Echocardiography shows asymmetric septal hypertrophy and systolic anterior motion of the mitral valve. The diagnosis is:
A.Dilated cardiomyopathy
B.Hypertrophic cardiomyopathy
C.Restrictive cardiomyopathy
D.Arrhythmogenic right ventricular cardiomyopathy
Explanation: Asymmetric septal hypertrophy with systolic anterior motion of the mitral valve causing dynamic left ventricular outflow obstruction is characteristic of hypertrophic cardiomyopathy, a leading cause of sudden cardiac death in young athletes.
7Which finding on ECG is most specific for hyperkalaemia and warrants urgent calcium gluconate to stabilise the myocardium?
A.Prolonged QT interval
B.Tall peaked T waves with widening QRS
C.U waves
D.Delta wave
Explanation: Hyperkalaemia produces tall peaked T waves progressing to widened QRS and a sine-wave pattern as it worsens. Intravenous calcium gluconate is given urgently to stabilise the cardiac membrane while other measures lower potassium.
8A 70-year-old presents with sudden severe tearing chest pain radiating to the back and a blood pressure difference between the two arms. The most appropriate initial imaging is:
A.CT angiography of the aorta
B.Coronary angiography
C.Ventilation-perfusion scan
D.Abdominal ultrasound
Explanation: Tearing chest pain radiating to the back with inter-arm blood pressure difference suggests acute aortic dissection. CT angiography of the aorta is the fastest, most accurate first-line imaging in a haemodynamically stable patient.
9Which of the following is the most common cause of secondary hypertension that should be screened for with a plasma aldosterone-to-renin ratio?
A.Phaeochromocytoma
B.Primary aldosteronism
C.Cushing syndrome
D.Coarctation of the aorta
Explanation: Primary aldosteronism (Conn syndrome) is the commonest endocrine cause of secondary hypertension. Screening uses the plasma aldosterone-to-renin ratio, with a high ratio indicating autonomous aldosterone production.
10In acute ST-elevation myocardial infarction, the single most important determinant of myocardial salvage and survival is:
A.Choice of statin
B.Time to reperfusion
C.Beta-blocker dose
D.Type of antiplatelet
Explanation: In STEMI, time to reperfusion is the dominant factor for myocardial salvage and survival, captured by the phrase 'time is muscle'. Primary PCI within recommended door-to-balloon times or timely fibrinolysis is the priority.

About the INI-SS Exam

The Institute of National Importance Super-Speciality Entrance Test (INI-SS) is the centralised entrance exam conducted by AIIMS New Delhi for admission to DM, MCh and MD (Hospital Administration) super-speciality programmes at Institutes of National Importance, including AIIMS New Delhi and the newer AIIMS, PGIMER Chandigarh, JIPMER Puducherry, NIMHANS Bengaluru and SCTIMST Thiruvananthapuram. It is held twice a year for the January and July sessions. Stage-I is a 90-minute computer-based test of 80 single-best-answer MCQs (+1 for correct, -1/3 for wrong) in English, with a 50% qualifying cutoff. The syllabus blends the basic/general component of the candidate's MD/MS feeder specialty with the foundations of the chosen super-speciality, so candidates are tested on both broad medicine or surgery and subspecialty fundamentals. Stage-II is a 20-mark departmental clinical assessment used only for AIIMS and PGIMER seat allocation.

Assessment

Stage-I: 80 single-best-answer multiple-choice questions, each worth 1 mark, with 1/3 mark deducted for wrong answers. Stage-II: a 20-mark departmental clinical/practical assessment for AIIMS and PGIMER seats only.

Time Limit

Stage-I lasts 90 minutes; Stage-II duration is department-dependent.

Passing Score

Candidates must obtain at least 50% in Stage-I (40 of 80 marks) to qualify. Final ranking and selection are competitive against available DM and MCh seats.

Exam Fee

Rs. 4,000 plus applicable transaction charges (non-refundable) for all applicants; PWBD candidates are exempted from the fee. (All India Institute of Medical Sciences (AIIMS), New Delhi)

INI-SS Exam Content Outline

60%

Feeder Specialty Fundamentals

About 60% of INI-SS questions test the basic and general component of the candidate's MD/MS feeder subject. Practice here covers general medicine and general surgery fundamentals, pathophysiology, pharmacology, microbiology, diagnostics and core internal-medicine and surgical principles that underlie super-speciality training.

40%

Super-Speciality Foundations

About 40% of questions cover the foundations of the chosen super-speciality course. Practice here covers cardiology, neurology, nephrology, gastroenterology and endocrinology for medical streams, and cardiothoracic, neurosurgical, urological and plastic-surgery basics for surgical streams.

Integrated

Clinical Reasoning and Recent Advances

Single-best-answer vignettes test diagnosis, investigation selection, drug choice and management across medicine and surgery, plus awareness of guideline-level recent advances. Practice here builds the decision-making expected at DM and MCh entry level.

How to Pass the INI-SS Exam

What You Need to Know

  • Passing score: Candidates must obtain at least 50% in Stage-I (40 of 80 marks) to qualify. Final ranking and selection are competitive against available DM and MCh seats.
  • Assessment: Stage-I: 80 single-best-answer multiple-choice questions, each worth 1 mark, with 1/3 mark deducted for wrong answers. Stage-II: a 20-mark departmental clinical/practical assessment for AIIMS and PGIMER seats only.
  • Time limit: Stage-I lasts 90 minutes; Stage-II duration is department-dependent.
  • Exam fee: Rs. 4,000 plus applicable transaction charges (non-refundable) for all applicants; PWBD candidates are exempted from the fee.

Keys to Passing

  • Complete 500+ practice questions
  • Score 80%+ consistently before scheduling
  • Focus on highest-weighted sections
  • Use our AI tutor for tough concepts

INI-SS Study Tips from Top Performers

1Revise your MD or MS feeder subject thoroughly, since roughly 60% of INI-SS questions test the basic and general component of that specialty rather than only super-speciality material.
2Build a strong base in the chosen super-speciality foundations (for example cardiology, neurology or the surgical super-specialities) using standard textbooks and current guidelines.
3Practise single-best-answer technique: many items are clinical vignettes where two options are close, so identify the single most appropriate answer rather than any acceptable one.
4Account for negative marking by skipping items where you can eliminate nothing; with -1/3 per wrong answer, guessing blindly across many questions lowers your score.
5Work through previous-year INI-SS and AIIMS papers, because repeated themes and high-yield concepts recur and help you gauge depth and timing.
6Pace yourself at roughly one minute per question so you can finish 80 questions in 90 minutes and still review flagged items before submitting.

Frequently Asked Questions

How many questions are on the INI-SS exam and how long is it?

Stage-I of INI-SS has 80 single-best-answer multiple-choice questions to be answered in 90 minutes. It is a computer-based test conducted in English by AIIMS New Delhi.

How is INI-SS marked and is there negative marking?

Each correct answer earns +1 mark and each wrong answer loses 1/3 mark. Unanswered or marked-for-review questions score zero, so the maximum Stage-I score is 80 marks.

What score do I need to qualify INI-SS?

A candidate must obtain at least 50% in Stage-I, that is 40 out of 80 marks, to qualify. Final seat allocation is competitive and based on merit rank against available DM and MCh seats.

What is the difference between INI-SS and NEET-SS?

INI-SS is conducted by AIIMS New Delhi for super-speciality seats at AIIMS, PGIMER, JIPMER, NIMHANS and SCTIMST, while NEET-SS is conducted by NBEMS for DM and MCh seats in most other medical colleges. They are separate exams with their own application processes.

What does the INI-SS syllabus cover?

The syllabus blends the basic and general component of the candidate's MD/MS feeder specialty (about 60%) with the foundations of the chosen super-speciality course (about 40%), so both broad medicine or surgery and subspecialty fundamentals are tested.

What is Stage-II of INI-SS?

Stage-II is a 20-mark departmental clinical and practical assessment conducted only for AIIMS and PGIMER seats. Candidates who score at least 50% in Stage-I and seek those seats are shortlisted for it; other institutes use the Stage-I merit list.