200+ Free FPGEE Practice Questions

Pass your Foreign Pharmacy Graduate Equivalency Examination exam on the first try — instant access, no signup required.

✓ No registration✓ No credit card✓ No hidden fees✓ Start practicing immediately

65-70% Pass Rate

200+ Questions

100% Free

1 / 200

Question 1

Score: 0/0

Which part of the nephron is primarily responsible for the reabsorption of glucose under normal conditions?

Proximal convoluted tubule

Loop of Henle

Distal convoluted tubule

Collecting duct

to track

2026 Statistics

Key Facts: FPGEE Exam

200

Total Questions

All scored

4h 30m

Exam Time

FPGEE format

75/100

Passing Score

Scaled scoring

37%

Clinical Sciences

Largest domain

$700

Exam Fee

NABP 2026

65-70%

Pass Rate

NABP data

The FPGEE has a pass rate of approximately 65-70% for foreign pharmacy graduates. The exam consists of 200 multiple-choice questions over 4.5 hours with scaled scoring (0-100, 75 passing). Pharmacy Practice and Clinical Sciences is the largest domain at 37%. The FPGEE is a critical step for internationally educated pharmacists seeking US licensure, followed by NAPLEX and state-specific exams.

Sample FPGEE Practice Questions

Try these sample questions to test your FPGEE exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 200+ question experience with AI tutoring.

1Which part of the nephron is primarily responsible for the reabsorption of glucose under normal conditions?

A.Proximal convoluted tubule

B.Loop of Henle

C.Distal convoluted tubule

D.Collecting duct

Explanation: The proximal convoluted tubule reabsorbs approximately 65% of filtered water and sodium, and virtually 100% of filtered glucose and amino acids under normal conditions. Glucose reabsorption occurs via sodium-glucose cotransporters (SGLT). The loop of Henle establishes the medullary concentration gradient, while the distal tubule and collecting duct perform fine-tuning of electrolyte balance.

2A patient presents with increased intracranial pressure. Which of the following structures is responsible for the production of cerebrospinal fluid (CSF)?

A.Arachnoid villi

B.Choroid plexus

C.Ependymal cells

D.Pia mater

Explanation: The choroid plexus, located in the ventricles of the brain, produces cerebrospinal fluid. It consists of capillaries and ependymal cells that filter blood plasma to form CSF. Arachnoid villi are responsible for CSF reabsorption into the venous system, while ependymal cells line the ventricles and central canal. The pia mater is the innermost meningeal layer.

3Which enzyme is primarily responsible for the conversion of angiotensin I to angiotensin II in the pulmonary circulation?

A.Renin

B.Angiotensin-converting enzyme (ACE)

C.Aldosterone synthase

D.Endothelin-converting enzyme

Explanation: Angiotensin-converting enzyme (ACE), found primarily on the surface of pulmonary endothelial cells, converts angiotensin I to the potent vasoconstrictor angiotensin II. This is the target of ACE inhibitor drugs. Renin is released by the kidney and converts angiotensinogen to angiotensin I. Aldosterone synthase produces aldosterone in the adrenal cortex.

4Which of the following best describes the function of the blood-brain barrier?

A.Prevents all substances from entering the brain

B.Allows lipid-soluble substances to pass while restricting water-soluble substances

C.Filters blood to produce cerebrospinal fluid

D.Regulates cerebral blood flow

Explanation: The blood-brain barrier consists of tight junctions between capillary endothelial cells, astrocyte foot processes, and a basement membrane. It is highly selective, allowing lipid-soluble substances (like oxygen, CO2, and some drugs) to passively diffuse while restricting water-soluble substances and large molecules. This protects the brain from toxins but also limits drug delivery.

5The hepatic portal vein carries blood from which of the following locations?

A.Liver to inferior vena cava

B.Gastrointestinal tract to liver

C.Liver to gallbladder

D.Spleen to kidney

Explanation: The hepatic portal vein carries nutrient-rich, deoxygenated blood from the gastrointestinal tract (stomach, intestines, pancreas, and spleen) to the liver. This allows the liver to process absorbed nutrients and detoxify substances before they enter systemic circulation. Blood then exits the liver via hepatic veins into the inferior vena cava.

6Which phase of the cardiac action potential is characterized by rapid depolarization due to sodium influx?

A.Phase 0

B.Phase 1

C.Phase 2

D.Phase 3

Explanation: Phase 0 (rapid depolarization) occurs when voltage-gated sodium channels open, allowing rapid Na+ influx. Phase 1 is initial repolarization, Phase 2 is the plateau phase (Ca2+ influx balanced by K+ efflux), and Phase 3 is repolarization due to K+ efflux. Understanding these phases is crucial for antiarrhythmic drug mechanisms.

7In the respiratory system, which cells produce surfactant to reduce alveolar surface tension?

A.Type I alveolar cells

B.Type II alveolar cells

C.Alveolar macrophages

D.Clara cells

Explanation: Type II alveolar cells (pneumocytes) produce and secrete pulmonary surfactant, a phospholipid-protein complex that reduces surface tension and prevents alveolar collapse. Type I cells form the gas exchange surface. Alveolar macrophages clear debris and pathogens. Clara cells in bronchioles secrete protective substances and can act as progenitor cells.

8Which of the following correctly describes the function of the lacteals in the small intestine?

A.Absorption of glucose

B.Absorption of dietary lipids

C.Secretion of digestive enzymes

D.Production of bile

Explanation: Lacteals are lymphatic capillaries in the intestinal villi that absorb dietary lipids and fat-soluble vitamins (packaged as chylomicrons). They transport these substances via the lymphatic system to the bloodstream. Glucose and amino acids are absorbed into blood capillaries. Digestive enzymes are secreted by pancreatic and intestinal cells.

9Which coenzyme is required as a cofactor for the enzyme pyruvate dehydrogenase?

A.FAD only

B.NAD+ only

C.Thiamine pyrophosphate, lipoic acid, FAD, NAD+, and CoA

D.Biotin only

Explanation: Pyruvate dehydrogenase is a complex requiring five coenzymes: thiamine pyrophosphate (vitamin B1), lipoic acid, FAD (riboflavin/B2), NAD+ (niacin/B3), and coenzyme A (pantothenic acid/B5). Deficiency of any of these vitamins can impair glucose metabolism. This is clinically relevant as thiamine deficiency causes beriberi and Wernicke-Korsakoff syndrome.

10Which metabolic pathway is the primary source of NADPH for reductive biosynthesis and antioxidant defense?

A.Glycolysis

B.Citric acid cycle

C.Pentose phosphate pathway

D.Gluconeogenesis

Explanation: The pentose phosphate pathway (hexose monophosphate shunt) generates NADPH and ribose-5-phosphate. NADPH is essential for fatty acid/cholesterol synthesis and maintaining reduced glutathione for antioxidant defense. G6PD deficiency, the most common enzyme deficiency worldwide, impairs this pathway, causing hemolytic anemia with oxidative stress.

About the FPGEE Exam

The FPGEE is a comprehensive examination for foreign pharmacy graduates seeking to become licensed pharmacists in the United States. The exam assesses competency across 4 domains: Foundational Biomedical Sciences (12%), Pharmaceutical Sciences (31%), Social, Behavioral, and Administrative Sciences (20%), and Pharmacy Practice and Clinical Sciences (37%). Passing the FPGEE is required before obtaining FPGEC certification and eligibility for NAPLEX.

Questions

200 scored questions

Time Limit

4 hours 30 minutes

Passing Score

75 (scaled)

Exam Fee

$700 (NABP (National Association of Boards of Pharmacy))

FPGEE Exam Content Outline

12%

Foundational Biomedical Sciences

Anatomy and physiology, biochemistry, medical microbiology, immunology, and pathophysiology essential for pharmacy practice

31%

Pharmaceutical Sciences

Medicinal chemistry, pharmacology, pharmaceutics and biopharmaceutics, pharmacokinetics, pharmacogenomics, compounding, and pharmaceutical calculations

20%

Social, Behavioral, and Administrative Sciences

Healthcare economics, pharmacoeconomics, healthcare systems, pharmacy law and ethics, professional communication, biostatistics, and social-behavioral aspects of health

37%

Pharmacy Practice and Clinical Sciences

Clinical pathophysiology, patient assessment, pharmacotherapy recommendations, patient safety, evidence-based practice, disease prevention, and health promotion across cardiovascular, endocrine, infectious disease, respiratory, GI, renal, and other therapeutic areas

How to Pass the FPGEE Exam

What You Need to Know

Passing score: 75 (scaled)
Exam length: 200 questions
Time limit: 4 hours 30 minutes
Exam fee: $700

Keys to Passing

Complete 500+ practice questions
Score 80%+ consistently before scheduling
Focus on highest-weighted sections
Use our AI tutor for tough concepts

FPGEE Study Tips from Top Performers

1Master US pharmacy law - Controlled Substances Act schedules, DEA regulations, pharmacy practice acts, and federal healthcare programs

2Focus on clinical pharmacotherapy - diabetes (ADA guidelines), cardiovascular (AHA/ACC), infectious diseases (IDSA), and respiratory (GOLD/GINA)

3Practice pharmaceutical calculations - dosing, IV rates, compounding, biostatistics, and pharmacokinetic calculations are heavily tested

4Understand US healthcare systems - Medicare/Medicaid, insurance formularies, pharmacy benefit management, and healthcare economics

5Review biomedical sciences - anatomy, physiology, biochemistry, and pathophysiology as they relate to drug action and disease states

Frequently Asked Questions

What is the FPGEE pass rate?

The FPGEE pass rate is approximately 65-70% for foreign pharmacy graduates, though rates vary significantly based on educational background, country of graduation, and preparation. The exam uses scaled scoring from 0-100, with 75 required to pass. First-time pass rates tend to be higher than repeat attempts.

How many questions are on the FPGEE?

The FPGEE contains 200 multiple-choice questions. You have 4 hours and 30 minutes to complete the exam. The exam covers 4 domains: Foundational Biomedical Sciences (12%), Pharmaceutical Sciences (31%), Social/Behavioral/Administrative Sciences (20%), and Pharmacy Practice/Clinical Sciences (37%).

What is the FPGEE passing score?

The FPGEE passing score is 75 on a scaled score of 0-100. Scaled scoring accounts for question difficulty across different exam forms. You must achieve this score to receive FPGEC certification and be eligible to take the NAPLEX.

What are the FPGEE eligibility requirements?

To take the FPGEE, you must: (1) Have graduated from a pharmacy program recognized by NABP, (2) Submit credentials through NABP's Electronic Profile System, (3) Meet English language proficiency requirements (TOEFL iBT 84+), and (4) Pay the exam fee ($700). Some candidates may need to complete additional coursework.

What is the path to US pharmacy licensure for foreign graduates?

The typical path is: (1) Apply for FPGEC certification through NABP, (2) Pass the FPGEE, (3) Pass the TOEFL iBT (if not exempt), (4) Receive FPGEC certification, (5) Pass the NAPLEX, (6) Pass your state pharmacy law exam (MPJE or state-specific), and (7) Apply for state licensure. The entire process typically takes 1-3 years.

How should I prepare for the FPGEE?

Plan for 3-6 months of intensive study. Focus on US pharmacy practice differences, clinical guidelines (ADA, AHA/ACC, GOLD, IDSA), pharmacy law (Controlled Substances Act, HIPAA, OBRA '90), and pharmaceutical calculations. Complete at least 3000-4000 practice questions covering all 4 domains. Many candidates benefit from FPGEE review courses and study groups.