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200+ Free ASCP MLT Practice Questions

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Questions by Category

Mlt-Microbiology42 questions
Mlt-Blood-Banking41 questions
Mlt-Chemistry41 questions
Mlt-Hematology29 questions
Mlt-Lab-Operations17 questions
Mlt-Urinalysis-Body-Fluids17 questions
Mlt-Immunology13 questions
2026 Statistics

Key Facts: ASCP MLT Exam

100

Exam Questions

ASCP BOC MLT exam page

2h 30m

Exam Time

ASCP BOC MLT exam page

400

Minimum Passing Score

ASCP 100-999 scoring scale

$235

Application Fee

ASCP BOC MLT exam page

2025-09-25

Guideline Revision

ASCP MLT content guideline

Pearson VUE

Testing Delivery

ASCP BOC MLT exam page

ASCP BOC lists the MLT exam as 100 questions in 2 hours 30 minutes with scores reported on a 100-999 scale and 400 as the minimum passing score. The current MLT application fee is $235, and ASCP's MLT content guideline was revised on September 25, 2025.

About the ASCP MLT Exam

The ASCP MLT exam certifies entry-level medical laboratory technicians in blood banking, chemistry, hematology, microbiology, urinalysis/body fluids, immunology, and laboratory operations. ASCP exams are delivered at Pearson VUE test centers.

Questions

100 scored questions

Time Limit

2 hours 30 minutes

Passing Score

Scaled score 400 (100-999)

Exam Fee

$235 (ASCP BOC / Pearson VUE)

ASCP MLT Exam Content Outline

14-19%

Blood Banking

ABO/Rh, antibody identification, compatibility testing, components, and transfusion reactions

17-22%

Chemistry

Electrolytes, renal/liver markers, acid-base interpretation, calculations, and quality control

15-20%

Hematology

CBC interpretation, morphology, coagulation studies, and hematologic disorders

17-22%

Microbiology

Specimen processing, organism identification, media, AST/QC, and rapid diagnostic methods

7-12%

Laboratory Operations

CLIA compliance, quality management, instrumentation, safety, and critical-result workflows

5-10%

Urinalysis & Body Fluids

Chemical and microscopic urinalysis plus CSF, synovial, and serous-fluid interpretation

5-10%

Immunology

Autoimmune testing, infectious serology algorithms, and immunoglobulin/complement interpretation

How to Pass the ASCP MLT Exam

What You Need to Know

  • Passing score: Scaled score 400 (100-999)
  • Exam length: 100 questions
  • Time limit: 2 hours 30 minutes
  • Exam fee: $235

Keys to Passing

  • Complete 500+ practice questions
  • Score 80%+ consistently before scheduling
  • Focus on highest-weighted sections
  • Use our AI tutor for tough concepts

ASCP MLT Study Tips from Top Performers

1Weight your study plan to the blueprint: chemistry, microbiology, hematology, and blood bank make up most scored content
2Practice calculation-heavy items under time pressure: anion gap, osmolality, corrected calcium, RBC indices, and coag correlations
3Build organism ID flow charts using Gram reaction plus key bench tests (oxidase, indole, coagulase, hemolysis, selective media)
4Use transfusion reaction decision trees so your first-action steps become automatic
5Track weak domains weekly and rotate targeted review blocks with mixed cumulative quizzes
6Train result-verification habits (QC rules, delta checks, critical-value reporting) for lab operations questions

Frequently Asked Questions

How many questions are on the ASCP MLT exam?

ASCP BOC lists the MLT exam at 100 questions with a 2 hour 30 minute testing time. Questions are multiple choice and mapped to the MLT content guideline domains.

What score do I need to pass ASCP MLT?

ASCP reports exam scores on a 100-999 scale. The minimum passing score is 400.

What topics are tested on ASCP MLT?

The MLT guideline domains are Blood Banking (14-19%), Chemistry (17-22%), Hematology (15-20%), Microbiology (17-22%), Laboratory Operations (7-12%), Urinalysis/Body Fluids (5-10%), and Immunology (5-10%).

How much is the ASCP MLT exam fee in 2026?

The current ASCP BOC MLT application fee is $235 (non-refundable) on the ASCP MLT exam page.

How should I study for ASCP MLT?

Use blueprint-weighted prep: 1) prioritize chemistry, microbiology, hematology, and blood bank first, 2) run daily mixed sets with calculations and interpretation, 3) review misses by domain, and 4) practice timing for a 2 hour 30 minute session.

Do MLT eligibility routes change over time?

Yes. ASCP route requirements are updated periodically (for example, ASCP notes Route 2 is no longer available as of January 1, 2022). Always verify your exact route on the current ASCP BOC MLT page before applying.

ASCP MLT Resources