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100+ Free DHA Pharmacist Exam Practice Questions

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A patient with chronic kidney disease is co-prescribed an ACE inhibitor, spironolactone, and a potassium supplement. What is the main risk the pharmacist must flag?

A
B
C
D
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Sample DHA Pharmacist Exam Practice Questions

Try these sample questions to test your DHA Pharmacist Exam exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1A 58-year-old man with type 2 diabetes and an eGFR of 28 mL/min/1.73m2 presents a new prescription for metformin 1 g twice daily. What is the most appropriate pharmacist action?
A.Contact the prescriber because metformin is contraindicated below an eGFR of 30 mL/min/1.73m2
B.Dispense as written because metformin is first-line for all diabetics
C.Reduce the dose to 500 mg twice daily and dispense without contacting the prescriber
D.Substitute glibenclamide because it is safer in renal impairment
Explanation: Metformin is contraindicated when eGFR falls below 30 mL/min/1.73m2 because of the risk of lactic acidosis. At an eGFR of 28 the prescriber should be contacted to switch therapy, so the pharmacist must intervene rather than dispense.
2A patient on warfarin starts a 7-day course of an antibiotic and the INR rises sharply to 6.5 with no bleeding. Which antibiotic most likely caused this interaction?
A.Cefalexin
B.Trimethoprim-sulfamethoxazole
C.Nitrofurantoin
D.Azithromycin
Explanation: Trimethoprim-sulfamethoxazole strongly inhibits CYP2C9, the enzyme that metabolizes the more potent S-enantiomer of warfarin, and also displaces warfarin from protein binding, markedly raising the INR. It is one of the highest-risk antibiotics for warfarin potentiation.
3A 24-year-old woman who is 12 weeks pregnant requests treatment for a confirmed lower urinary tract infection. Which oral antibiotic should the pharmacist recommend avoiding in this trimester?
A.Nitrofurantoin
B.Cefalexin
C.Trimethoprim
D.Amoxicillin
Explanation: Trimethoprim is a folate antagonist and is contraindicated in the first trimester because it increases the risk of neural tube defects. Folate is critical during early organogenesis, so trimethoprim should be avoided in this period.
4What volume of a 50% w/v magnesium sulfate solution is required to provide 5 g of magnesium sulfate?
A.5 mL
B.25 mL
C.20 mL
D.10 mL
Explanation: A 50% w/v solution contains 50 g per 100 mL, which equals 0.5 g/mL. To obtain 5 g you divide 5 g by 0.5 g/mL, giving 10 mL.
5Under UAE pharmacy regulations, controlled (narcotic) medicines such as morphine must be stored in what manner within a community pharmacy?
A.In a locked, secured cabinet with restricted access and a maintained register
B.On the open dispensing shelf with other prescription medicines
C.In the refrigerator alongside vaccines
D.In the patient counseling area for quick access
Explanation: Controlled narcotic medicines must be kept in a locked, secured cabinet with restricted access, and all transactions must be recorded in a controlled-drug register. This requirement supports the UAE narcotic control law and prevents diversion.
6A mother asks for advice on her 3-year-old child who has a fever of 38.8 C. Which over-the-counter antipyretic dosing recommendation is most appropriate?
A.Aspirin 300 mg every 4 hours
B.Paracetamol 15 mg/kg every 4-6 hours, maximum 4 doses in 24 hours
C.Ibuprofen 30 mg/kg as a single dose
D.Paracetamol 50 mg/kg as a single loading dose
Explanation: Paracetamol dosed at 15 mg/kg every 4-6 hours, with a maximum of four doses in 24 hours, is the standard safe pediatric antipyretic regimen. It avoids both aspirin in children and overdosing of paracetamol.
7A drug has a half-life of 8 hours and follows first-order elimination. Approximately how long after stopping a continuous infusion will it take to reach steady-state elimination of about 97% of the drug from the body?
A.8 hours
B.16 hours
C.40 hours
D.80 hours
Explanation: It takes approximately five half-lives to eliminate about 97% of a drug. With an 8-hour half-life, five half-lives equal 40 hours. This rule also applies in reverse for reaching steady state during dosing.
8While checking a prescription, a pharmacist notices a verbal order for vincristine to be administered intrathecally. What is the correct action?
A.Dispense the vincristine for intrathecal use as ordered
B.Substitute methotrexate and give it intravenously instead
C.Dilute the vincristine further and label it for intrathecal use
D.Refuse and clarify, because intrathecal vincristine is invariably fatal and must only be given intravenously
Explanation: Vincristine given intrathecally causes ascending paralysis and death and must never be administered by that route; it is for intravenous use only. This is a sentinel medication-safety error, and the pharmacist must refuse and clarify the order.
9Which of the following is the primary purpose of conducting a sterility test using aseptic technique in a Grade A laminar airflow hood?
A.To prevent microbial contamination of parenteral preparations
B.To increase the shelf life of tablets
C.To improve the taste of oral suspensions
D.To speed up the dissolution of capsules
Explanation: Sterile compounding in a Grade A laminar airflow environment prevents microbial contamination of injectable and parenteral products that bypass the body's natural barriers. Contaminated parenterals can cause severe bloodstream infections.
10A patient taking simvastatin 40 mg is newly prescribed clarithromycin. What is the principal concern and most appropriate action?
A.No concern; both drugs can be continued together
B.Risk of rhabdomyolysis because clarithromycin inhibits CYP3A4; temporarily withhold simvastatin during the antibiotic course
C.Risk of QT prolongation only; reduce the clarithromycin dose
D.Risk of statin failure; double the simvastatin dose
Explanation: Clarithromycin is a potent CYP3A4 inhibitor that markedly raises simvastatin levels, increasing the risk of myopathy and rhabdomyolysis. The recommended action is to suspend simvastatin during the short clarithromycin course.

About the DHA Pharmacist Exam Exam

The DHA Pharmacist Licensing Assessment is the computer-based examination required to register and practice as a pharmacist in Dubai. Per the official DHA CBT Guideline, the Pharmacist exam (code PHO5481) has 150 multiple-choice questions, a 3-hour limit, a USD 240 Prometric fee and a 60% pass mark. Some third-party prep sites cite 120 questions; the official guideline figure of 150 is used here.

Assessment

150 single-best-answer multiple-choice questions delivered as a computer-based test through Prometric (code PHO5481), spanning the 14 official pharmacist content areas from clinical pharmacology and therapeutics to compounding, pharmacokinetics and UAE pharmacy law.

Time Limit

3 hours (180 minutes)

Passing Score

60% per the official DHA CBT Guideline; results are reported as Pass or Fail on the Sheryan portal

Exam Fee

USD 240, paid to Prometric at scheduling (non-refundable) (Dubai Health (formerly DHA))

DHA Pharmacist Exam Exam Content Outline

20%

Clinical Pharmacology & Therapeutic Decision Making

Mechanisms of action, drug interactions, adverse effects, contraindications and evidence-based therapy selection across major organ systems and disease states.

15%

Pharmaceutical Care & Disease State Management

Patient-centered management and counseling for diabetes, asthma, heart failure, gout, anticoagulation, infections and other chronic and acute conditions.

10%

Pharmacy Calculation & Compounding

Concentration, ratio- and percentage-strength, weight-based and BSA dosing, infusion-rate and dispensing-quantity calculations.

10%

Pharmacy Law & Ethics

UAE pharmacy regulation, controlled-drug control, prescription validity, substitution, confidentiality, pharmacovigilance, registration and disposal.

9%

Pharmacokinetics

Half-life, bioavailability, first-pass metabolism, volume of distribution, protein binding, zero- and first-order kinetics and therapeutic drug monitoring.

8%

Over the Counter Medication

Responsible self-care and referral for cough, cold, allergy, heartburn, constipation, pain, fever and emergency contraception.

6%

Medication Safety

High-alert medicines, route and dosing errors, error-prone abbreviations, reconciliation, duplicate therapy and hypersensitivity recognition.

5%

Sterile & Nonsterile Compounding

Aseptic technique, containment hardware, parenteral and TPN compatibility, suppository bases and cytotoxic preparation.

4%

Pharmaceutics / Biopharmaceutics

Dosage form design, the Biopharmaceutics Classification System, dissolution kinetics and excipient function.

4%

Toxicology

Poisoning recognition and antidotes for organophosphates, paracetamol, opioids and tricyclic antidepressants.

3%

Infection Control

Hand hygiene, safe injection and sharps practice, vaccine handling and immunocompromised cautions.

2%

Pharmacognosy & Dietary Supplements

Natural-product pharmacology, herb-drug interactions and supplement-related bleeding risk.

2%

Medicinal Chemistry

Structure-activity relationships and selective toxicity of beta-lactams, sulfonamides and related classes.

2%

Clinical Pharmacogenomics

Genotype-guided prescribing such as CYP2C19/clopidogrel and HLA-B*57:01/abacavir.

How to Pass the DHA Pharmacist Exam Exam

What You Need to Know

  • Passing score: 60% per the official DHA CBT Guideline; results are reported as Pass or Fail on the Sheryan portal
  • Assessment: 150 single-best-answer multiple-choice questions delivered as a computer-based test through Prometric (code PHO5481), spanning the 14 official pharmacist content areas from clinical pharmacology and therapeutics to compounding, pharmacokinetics and UAE pharmacy law.
  • Time limit: 3 hours (180 minutes)
  • Exam fee: USD 240, paid to Prometric at scheduling (non-refundable)

Keys to Passing

  • Complete 500+ practice questions
  • Score 80%+ consistently before scheduling
  • Focus on highest-weighted sections
  • Use our AI tutor for tough concepts

DHA Pharmacist Exam Study Tips from Top Performers

1Download the official DHA CBT Guideline for the Pharmacist (PHO5481) exam and weight your study toward clinical pharmacology, pharmacotherapy and pharmacy calculations, which carry the most applied questions.
2Drill pharmacy calculations (concentration, ratio strength, weight-based and infusion-rate problems) under timed conditions, as the exam gives roughly 72 seconds per question across 150 items in 180 minutes.
3Review UAE-specific pharmacy law, controlled-drug handling, pharmacovigilance and high-alert medication safety, then use full-length timed mocks and analyze every wrong answer.

Frequently Asked Questions

How many questions are on the DHA pharmacist exam and how long is it?

Per the official DHA CBT Guideline, the Pharmacist exam (code PHO5481) has 150 multiple-choice questions with a 3-hour (180-minute) limit, delivered as a Prometric computer-based test. Some prep sites quote 120 questions, but the official guideline lists 150.

What is the passing score for the DHA pharmacist exam?

The official DHA CBT Guideline lists a 60% pass score for the Pharmacist exam (PHO5481). Results are reported as Pass or Fail on the Sheryan portal, and candidates have a maximum of three attempts across UAE authorities.

How much does the DHA pharmacist exam cost?

The Prometric CBT fee is USD 240, paid directly to Prometric when scheduling. This is separate from the DHA Sheryan application fee, DataFlow primary source verification and final license activation fees.

What topics does the DHA pharmacist exam cover?

The official exam coverage lists 14 areas: toxicology, medicinal chemistry, sterile and nonsterile compounding, pharmaceutics/biopharmaceutics, pharmacognosy and dietary supplements, pharmacy calculation, clinical pharmacogenomics, infection control, pharmacokinetics, pharmaceutical care and disease state management, medication safety, over-the-counter medication, pharmacy law and ethics, and clinical pharmacology and therapeutic decision making.