100+ Free ACPV Practice Questions

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Why are multivalent or region-specific vaccines often required for infectious bronchitis virus (IBV) control?

IBV is exclusively transmitted vertically

IBV vaccines have very short duration of immunity

IBV is only susceptible to inactivated vaccines

IBV has limited cross-protection between serotypes

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Key Facts: ACPV Exam

AVMA RVSO

Recognized 1985

ACPV (under AAAP)

NPIP

National Plan

Pullorum, MG/MS, AI surveillance

OIE

HPAI Reportable

IVPI ≥1.2 / HA cleavage

AMDUCA

No FQs in poultry

Banned 2005

ACPV is the AVMA-recognized vet specialty board for poultry medicine. Master HPAI/LPAI (IVPI ≥1.2 or HA cleavage site), ND pathotypes (velo/meso/lentogenic), IBDV bursal targeting + Rispens vaccination, Eimeria coccidiosis (E. tenella cecal, E. maxima mid-gut), NPIP (pullorum/MG/MS/AI testing), FAD reporting (HPAI/vND), and AMDUCA prohibited drugs (fluoroquinolones in food poultry).

Sample ACPV Practice Questions

Try these sample questions to test your ACPV exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1Which avian influenza virus subtype is most commonly associated with highly pathogenic outbreaks in domestic poultry in recent years?

A.H1N1

B.H5N1

C.H3N2

D.H9N2

Explanation: H5N1 (along with H5N2) has been the dominant subtype causing HPAI outbreaks globally, including the panzootic affecting commercial and backyard poultry across multiple continents.

2What molecular feature most reliably distinguishes HPAI from LPAI strains of H5 or H7 influenza viruses?

A.Neuraminidase stalk length

B.Multiple basic amino acids at the HA cleavage site

C.PB2 627K mutation

D.M2 ion channel composition

Explanation: HPAI H5/H7 viruses possess multiple basic amino acids at the hemagglutinin (HA) cleavage site, allowing systemic activation by ubiquitous furin-like proteases and resulting in multi-organ disease.

3The intravenous pathogenicity index (IVPI) threshold defining a highly pathogenic avian influenza virus by WOAH (OIE) standards is at least:

A.0.7

B.1.0

C.1.2

D.1.5

Explanation: An IVPI greater than or equal to 1.2 in 6-week-old chickens classifies an avian influenza virus as highly pathogenic per WOAH (OIE) reference criteria.

4Newcastle disease is caused by which virus?

A.Avian paramyxovirus type 1 (APMV-1)

B.Avian coronavirus

C.Avian reovirus

D.Avian adenovirus type 4

Explanation: Newcastle disease is caused by virulent strains of avian paramyxovirus type 1 (APMV-1), a member of the genus Orthoavulavirus in the family Paramyxoviridae.

5Which Newcastle disease pathotype causes the most severe disease with high mortality and is reportable to WOAH?

A.Lentogenic

B.Mesogenic

C.Velogenic

D.Asymptomatic enteric

Explanation: Velogenic strains of Newcastle disease virus produce high mortality (often greater than 90 percent) with viscerotropic or neurotropic forms and are internationally reportable.

6Infectious bronchitis virus (IBV) belongs to which virus family?

A.Coronaviridae

B.Paramyxoviridae

C.Birnaviridae

D.Herpesviridae

Explanation: IBV is a Gammacoronavirus in the family Coronaviridae, an enveloped, positive-sense, single-stranded RNA virus with characteristic spike (S) glycoproteins.

7Why are multivalent or region-specific vaccines often required for infectious bronchitis virus (IBV) control?

A.IBV has limited cross-protection between serotypes

B.IBV vaccines have very short duration of immunity

C.IBV is only susceptible to inactivated vaccines

D.IBV is exclusively transmitted vertically

Explanation: IBV demonstrates extensive serotype and genotype diversity (e.g., Massachusetts, Connecticut, Arkansas, Delaware-072, GA-08, QX), and cross-protection between serotypes is limited, requiring matched vaccine programs.

8Which IBV pathotype is most associated with renal failure, urolithiasis, and high mortality in young birds?

A.Respiratory

B.Nephropathogenic

C.Enteric

D.Reproductive

Explanation: Nephropathogenic IBV strains (e.g., some Australian T strain, certain Massachusetts variants, QX) cause interstitial nephritis, urate deposition, and elevated mortality especially in broilers.

9Which target tissue is preferentially infected by infectious bursal disease virus (IBDV)?

A.Bursa of Fabricius

B.Thymus

C.Spleen germinal centers only

D.Bone marrow

Explanation: IBDV (Birnaviridae, genus Avibirnavirus) preferentially infects actively dividing IgM-positive B lymphocytes in the bursa of Fabricius, causing acute lysis followed by atrophy and immunosuppression.

10The most important consequence of subclinical IBDV infection in young chicks is:

A.Permanent immunosuppression and vaccine failure

B.Acute high mortality

C.Chronic respiratory disease

D.Skeletal abnormalities

Explanation: Subclinical IBDV in chicks under 3 weeks causes lasting B-cell depletion and immunosuppression, leading to vaccine failures, secondary infections (E. coli, Salmonella, gangrenous dermatitis), and poor performance.

About the ACPV Exam

AVMA-recognized veterinary specialty board for poultry medicine. Covers viral diseases (HPAI/LPAI, ND, IBV, IBDV/Gumboro, Marek's, ALV, REV, fowlpox, ILT), bacterial diseases (Salmonella, APEC, Mycoplasma, Pasteurella, Clostridium NetB, Campylobacter), parasitic (Eimeria coccidiosis, Histomonas blackhead, Ascaridia), nutrition and management, anatomy and physiology, biosecurity and public health (NPIP, FAD reporting), and regulatory food safety (FSIS, AMDUCA, VFD, withdrawal times).

Questions

100 scored questions

Time Limit

Per ACPV

Passing Score

Per ACPV

Exam Fee

Per ACPV (ACPV (under AAAP))

ACPV Exam Content Outline

25%

Viral Diseases

HPAI/LPAI, ND, IBV, IBDV/Gumboro, Marek's, ALV, REV, fowlpox, ILT

20%

Bacterial Diseases

Salmonella, E. coli/APEC, Mycoplasma, Pasteurella, Clostridium NetB, Campylobacter

15%

Nutrition & Management

Feed formulation, water, lighting (23L:1D broilers, 14-16L layers), ventilation

10%

Parasitic

Eimeria coccidiosis, Histomonas blackhead (cecal worm vector), Ascaridia, mites/lice

10%

Anatomy & Physiology

Avian anatomy (9 air sacs), reproduction, GI, immune (bursa, Harderian)

10%

Biosecurity & Public Health

Biosecurity (Danish entry, AIAO), NPIP, FAD reporting

10%

Regulatory & Food Safety

FSIS HACCP, AMDUCA, VFD, withdrawal times, FDA-CVM

How to Pass the ACPV Exam

What You Need to Know

Passing score: Per ACPV
Exam length: 100 questions
Time limit: Per ACPV
Exam fee: Per ACPV

Keys to Passing

Complete 500+ practice questions
Score 80%+ consistently before scheduling
Focus on highest-weighted sections
Use our AI tutor for tough concepts

ACPV Study Tips from Top Performers

1Master HPAI/LPAI distinction: IVPI ≥1.2 OR HA cleavage site genetics; both subject to OIE reporting

2Memorize Eimeria species by location: E. tenella cecal, E. acervulina duodenum, E. maxima mid-gut, E. necatrix mid-gut hemorrhagic

3Drill Marek's vaccination strains: Rispens (CVI988) most effective; HVT and SB-1 also used

4Know NPIP testing: pullorum (whole-blood plate agglutination), MG/MS, AI surveillance

5Apply AMDUCA prohibitions in food poultry: fluoroquinolones (banned 2005), chloramphenicol, DES, dimetridazole

Frequently Asked Questions

How is HPAI distinguished from LPAI?

OIE definitions: HPAI (Highly Pathogenic Avian Influenza) — H5 or H7 subtype with intravenous pathogenicity index (IVPI) ≥1.2 in 6-week-old chickens, OR multiple basic amino acids at the HA cleavage site (genetic predictor). LPAI lacks both. HPAI is reportable to OIE; emergency depopulation + indemnity required. H5N1 since 2022 has caused unprecedented US losses (commercial layers, dairy cattle, mammals). Surveillance via NPIP-AI testing.

What is the difference between SE and S. Pullorum?

Salmonella Enteritidis (SE) is the major foodborne human pathogen from poultry — Egg Safety Rule (FDA) requires layer flocks to test for SE and divert eggs if positive. S. Pullorum causes Pullorum Disease (white diarrhea, septicemia in chicks) and is essentially eradicated from US commercial flocks via NPIP testing of breeders (whole-blood plate agglutination). S. Gallinarum (fowl typhoid) is also NPIP-controlled.

Why was enrofloxacin banned in poultry?

FDA-CVM withdrew enrofloxacin (a fluoroquinolone) from poultry use in 2005 because of evidence of fluoroquinolone-resistant Campylobacter jejuni in retail chicken — a public health concern (FQ resistance limits human treatment options). AMDUCA permits ELDU but PROHIBITS fluoroquinolones in food-producing animals. This was a landmark case in antibiotic stewardship in food animal medicine. VFD now governs medically important antibiotics in feed.

How should I study for ACPV?

Plan 500-1,000 hours over your study period. Master Diseases of Poultry (Swayne et al, current edition) cover-to-cover — primary reference. Read AAAP avian disease compendia for major pathogens. Attend AAAP/AVMA annual meetings. Develop case experience across commercial broilers, layers, breeders, turkeys, and backyard flocks. Publications and case logs required as part of board application.