Free MRCP(UK) Part 1 Exam Prep
Membership of the Royal Colleges of Physicians of the United Kingdom (MRCP(UK)) Part 1 Examination
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Clinical Sciences & Pharmacology FoundationYou are here
Master foundational sciences including genetics, molecular biology, immunology, physiology, statistics, and clinical pharmacology representing 40 exam questions.
Core High-Yield Medical Specialties
Focus on high-volume specialties including cardiology, respiratory, gastroenterology, endocrinology, neurology, and renal medicine.
Additional Specialties & Systemic Medicine
Cover rheumatology, infectious diseases, haematology, dermatology, psychiatry, oncology, palliative care, and ophthalmology.
Timed Best-of-Five Mocks & Equating Practice
Complete full-length 100-question timed papers adhering to the 1.8-minute pace required for the two 3-hour papers.
Can You Take the MRCP(UK) Part 1 Exam?
Check if you meet the basic eligibility requirements
Free MRCP(UK) Part 1 Prep Tools
125+ Practice Questions
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What You'll Study
27 chapters covering the exam topics in this guide
MRCP(UK) Part 1: Exam Overview, Blueprint & Strategy
3 sections
Clinical Sciences: Cellular, Genetic & Molecular Medicine
6 sections
Clinical Sciences: Anatomy, Physiology & Immunology
3 sections
Clinical Sciences: Statistics, Epidemiology & Trial Design
3 sections
Clinical Pharmacology, Therapeutics & Toxicology
5 sections
Cardiology: Coronary Artery Disease & Heart Failure
3 sections
Cardiology: Arrhythmias, Valvular & Pericardial Disease
5 sections
Respiratory Medicine: Airway & Parenchymal Lung Disease
4 sections
Respiratory Medicine: Vascular, Pleural & Sleep Disorders
3 sections
Gastroenterology: Luminal Gastrointestinal Disease
6 sections
Gastroenterology: Liver, Biliary & Pancreatic Disease
5 sections
Endocrinology & Diabetes: Diabetes & Thyroid
5 sections
Endocrinology & Diabetes: Adrenal, Pituitary & Calcium
6 sections
Renal Medicine: AKI, Glomerular & Tubulointerstitial Disease
4 sections
Renal Medicine: Fluid, Electrolytes & Acid-Base Balance
3 sections
Neurology: Cerebrovascular, Headache & Demyelinating Disease
4 sections
Neurology: Epilepsy, Movement Disorders & Neuromuscular Disease
3 sections
Rheumatology: Inflammatory Arthritis & Connective Tissue Disease
6 sections
Rheumatology: Systemic Vasculitis & Crystal Arthropathy
3 sections
Infectious Diseases & Tropical Medicine
7 sections
Haematology: Anaemias & Red Cell Disorders
3 sections
Haematology: Malignancy, Coagulation & Transfusion Medicine
6 sections
Psychiatry in General Medicine
3 sections
Geriatric Medicine
2 sections
Dermatology
2 sections
Oncology & Palliative Medicine
3 sections
Medical Ophthalmology
2 sections
MRCP(UK) Part 1 Exam Details
Membership of the Royal Colleges of Physicians of the United Kingdom (MRCP(UK)) Part 1 Examination
Administered by Federation of the Royal Colleges of Physicians of the UK (RCP London, RCP Edinburgh, RCPS Glasgow)
Exam Content Breakdown
Based on the official Federation of the Royal Colleges of Physicians of the UK (RCP London, RCP Edinburgh, RCPS Glasgow) content outline
Approximately 25 of the 200 questions. Cell, molecular and membrane biology (2), clinical anatomy (3), clinical biochemistry and metabolism (4), clinical physiology (4), genetics (3), immunology (4) and statistics, epidemiology and evidence-based medicine (5).
Approximately 15 of the 200 questions. Pharmacokinetics, pharmacodynamics, cytochrome P450 interactions, adverse drug reactions, therapeutic drug monitoring and the management of poisoning.
Approximately 14 of the 200 questions. Acute coronary syndromes, heart failure, arrhythmias, valvular and pericardial disease, cardiomyopathy and ECG interpretation.
Approximately 14 of the 200 questions. Diabetes and its emergencies, thyroid disease, pituitary and adrenal disorders, calcium homeostasis and metabolic bone disease.
Approximately 14 of the 200 questions. Peptic ulcer disease, coeliac and inflammatory bowel disease, gastrointestinal bleeding, viral and autoimmune liver disease and complications of cirrhosis.
Approximately 14 of the 200 questions. Sepsis and meningitis, HIV and opportunistic infection, tuberculosis, malaria, imported fevers and antimicrobial therapy.
Approximately 14 of the 200 questions. Stroke and TIA, headache disorders, demyelination, epilepsy, movement disorders and neuromuscular disease.
Approximately 14 of the 200 questions. Acute kidney injury, glomerulonephritis, tubulointerstitial and inherited renal disease, electrolyte disorders and acid-base balance.
Approximately 14 of the 200 questions. Asthma and COPD, interstitial lung disease, pneumonia, pulmonary embolism, pleural disease and respiratory failure.
Approximately 14 of the 200 questions. Rheumatoid arthritis, spondyloarthropathies, connective-tissue disease, systemic vasculitis, crystal arthropathy and DMARD monitoring.
Approximately 10 of the 200 questions. Anaemias and haemoglobinopathies, leukaemias, lymphomas, plasma cell dyscrasias, coagulation disorders and transfusion medicine.
Approximately 9 of the 200 questions. Mood and psychotic disorders in medical patients, psychopharmacology, serotonin syndrome, substance misuse and the Mental Capacity Act.
Approximately 8 of the 200 questions. Psoriasis and eczema, immunobullous disease, severe cutaneous adverse reactions and skin malignancy.
Approximately 8 of the 200 questions. Comprehensive geriatric assessment, frailty, delirium, falls, polypharmacy and pressure ulcers.
Approximately 5 of the 200 questions. Neutropenic sepsis, metastatic spinal cord compression, superior vena cava obstruction, malignant hypercalcaemia and tumour lysis syndrome.
Approximately 4 of the 200 questions. The acute red eye, sudden painless visual loss and retinopathy in systemic disease.
Approximately 4 of the 200 questions. The WHO analgesic ladder, strong opioid titration and conversion, syringe drivers and terminal symptom control.
What's Included
27 Chapters
Complete exam coverage
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What's Next After the MRCP(UK) Part 1?
After passing the MRCP(UK) Part 1, you can pursue these career paths
MRCP(UK) Part 2 Written
Pass the second written exam assessing complex clinical scenarios, investigation data, and imaging.
MRCP(UK) PACES
Practical Assessment of Clinical Examination Skills required for full MRCP(UK) diploma and specialist training entry.
Higher Specialty Training (ST4+)
Progress to competitive specialty registrar training across UK deaneries in cardiology, respiratory, gastroenterology, or other physician specialties.
MRCP(UK) Part 1 Exam FAQ
Official Federation of the Royal Colleges of Physicians of the UK (RCP London, RCP Edinburgh, RCPS Glasgow) Resources
Verify information with these official sources
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