6.2 Endangered species, pollinators & non-target protection

Key Takeaways

  • The Endangered Species Act protects listed species and their critical habitat; EPA 'Endangered Species' label statements point applicators to county-level use limitations in Bulletins Live! Two.
  • Applicators must look up and follow the Bulletins Live! Two bulletin for the application's county and month, and its limitations are as binding as any other label directive.
  • Protect bees by not applying insecticides to blooming plants while bees forage and by applying in the evening or night when bees are not foraging.
  • Read bee-hazard and pollinator label statements, note residual toxicity, and notify nearby beekeepers before applying highly bee-toxic products.
  • The label's 'Environmental Hazards' section warns of risks to fish, birds, and beneficial insects; prevent drift and runoff and clean up spilled granules and baits to protect them.
Last updated: July 2026

The Endangered Species Act

The Endangered Species Act (ESA) is a federal law that protects plants and animals listed as threatened or endangered, along with their designated critical habitat. EPA must ensure that pesticide use does not jeopardize listed species, and it passes those limits to the applicator through the label. Harming a listed species or violating an ESA-based label instruction can bring federal penalties.

Bulletins Live! Two

When a product could harm a listed species in a given area, its label carries an "Endangered Species" statement directing the applicator to check for local use limitations. Those limitations are published in Bulletins Live! Two (BLT), EPA's online bulletin system. Before applying, the applicator must look up the bulletin for the specific county and month of the application and follow every restriction it lists, such as reduced rates, additional buffer zones, seasonal timing, or an outright prohibition. Bulletins are date-limited (generally checked no more than six months before use), and obtaining and following them is the applicator's responsibility. An endangered-species limitation is as binding as any other label directive.

General Practices for Listed Species

  • Identify sensitive habitats and water near the site before treating.
  • Observe all buffer zones and setbacks from habitat and water.
  • Control drift and runoff using the practices in Section 6.1.
  • Time applications to avoid vulnerable life stages of the species.

Protecting Pollinators

Bees and other pollinators, including honey bees, native bees, and butterflies, are enormously valuable, pollinating a large share of food crops, and they are highly vulnerable to insecticides. Many labels carry a "Protection of Pollinators" box or a bee-hazard icon.

Bees are exposed to pesticides in several ways: direct contact with spray droplets while foraging, contaminated pollen and nectar they carry back to the colony, residues on foliage and blooming weeds, and contaminated water or guttation droplets. Because foragers bring contamination home, a single poorly timed application can harm the entire colony, not just the bees that were in the field. Systemic insecticides can also move into a plant's pollen and nectar, so both timing and product choice matter.

Timing Around Bloom

  • Do not apply insecticides to blooming or flowering plants while bees are foraging.
  • Apply in the late evening or at night (or very early morning) when bees are not foraging and temperatures are lower; foraging generally stops after dusk.
  • Avoid treating when nearby weeds or a cover crop are in bloom, and mow flowering weeds before you spray.

Reading the Label and Communicating

  • Read and follow every bee-hazard and pollinator statement, such as "This product is highly toxic to bees exposed to direct treatment or residues on blooming crops or weeds."
  • Note the residual toxicity, because some products stay toxic to bees for hours or days after the spray dries.
  • Notify nearby beekeepers before applying so hives can be covered or moved.
  • Choose less bee-toxic products when possible; dusts and microencapsulated formulations are especially hazardous because foragers carry the particles back to the hive.
  • Reduce drift onto adjacent blooming areas.

Protecting Other Non-Target Organisms

Non-target organisms include fish and aquatic invertebrates, birds, mammals, amphibians, and beneficial insects (predators and parasitoids), plus the habitat they need. Labels list specific warnings in the "Environmental Hazards" section, and those statements are enforceable.

GroupMain riskProtective action
Fish & aquatic lifeDrift or runoff into water; many products are "highly toxic to fish"Keep buffers, prevent runoff and drift, keep rinsate out of waterways
Birds & wildlifeEating granules, treated seed, or bait; spray on foodClean up spilled granules, avoid treating feeding areas
Beneficial insectsBroad-spectrum insecticides kill natural enemies, causing pest flare-upsUse selective products, spot-treat, follow IPM
Bees & pollinatorsContact with spray or residues on bloomApply when bees are not foraging; avoid bloom
Pets & livestockContaminated forage or waterObserve grazing and entry intervals; keep them off treated areas

Integrated Pest Management (IPM) is the applicator's strongest tool for protecting the whole environment. By monitoring pests, using thresholds to decide whether treatment is truly needed, and combining cultural, mechanical, biological, and least-toxic chemical controls, IPM lowers the total amount of pesticide released. Selective, narrow-spectrum products spare the predators and parasitoids that keep pests in check, while broad-spectrum sprays can wipe them out and trigger a pest rebound or a secondary pest outbreak. Spot-treating only infested areas, rotating modes of action, and preserving field-edge habitat for beneficial insects all reduce non-target harm while still controlling the pest.

Key general rules tie it together:

  • Read the "Environmental Hazards" statements, which name the specific concern and the required precaution and are enforceable.
  • Prevent drift and runoff, because the same steps that protect water and pollinators also protect fish, birds, and beneficials.
  • Clean up spills and spilled granules or baits so birds and mammals cannot eat them.
  • Favor Integrated Pest Management (IPM), using the least-toxic effective option, spot-treating, and conserving natural enemies to reduce the overall pesticide load.
  • Mix, store, and dispose of pesticides and rinsate away from water and wildlife areas.

By combining habitat awareness, correct timing, full label compliance (including Bulletins Live! Two and pollinator statements), and drift and runoff control, applicators meet their legal duty to protect endangered species and the wider environment.

Test Your Knowledge

An 'Endangered Species' statement on a pesticide label directs the applicator to county-specific use limitations. Where are those limitations found?

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Test Your Knowledge

What is the best way to protect foraging honey bees when using an insecticide that is highly toxic to bees?

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Test Your Knowledge

A label's 'Environmental Hazards' section warns that a product is 'highly toxic to fish.' Which action best protects surface-water aquatic life?

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