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6.4 Modifiers Every Biller Must Know

Key Takeaways

  • Modifier 26 reports the professional component only, modifier TC reports the technical component only, and reporting a global service uses no split modifier.
  • Modifier 25 reports a significant, separately identifiable E/M service on the same day as a procedure; modifier 57 reports the E/M visit at which the decision for major surgery was made.
  • Postoperative-period modifiers 58, 78, and 79 describe a related staged service, an unplanned related return to the OR, and an unrelated procedure during the global period, respectively.
  • Modifiers 24, 76, 77, and 91 handle repeat and unrelated services; modifier 50 reports a bilateral procedure, and 51 reports multiple procedures on one claim.
  • Medicare ABN modifiers signal expected payment outcomes: GA = ABN on file, GZ = no ABN expected denial, GY = statutorily excluded, GX = voluntary ABN for a non-covered item.
Last updated: May 2026

What Modifiers Do

A modifier is a two-character code appended to a CPT or HCPCS code. It does not change the code's definition — it adds context: a service was altered, a component was billed, or a special circumstance applied. Incorrect or missing modifiers are one of the most common denial reasons a biller resolves, so modifier selection is heavily tested on the CPB exam.

Modifier Index

ModifierNameWhen the biller uses it
22Increased procedural serviceSubstantially greater work than the code typically requires
24Unrelated E/M during a postoperative periodE/M unrelated to the original surgery, within the global period
25Significant, separately identifiable E/MA distinct E/M service on the same day as a minor procedure
26Professional componentPhysician's interpretation only (no equipment/technician)
TCTechnical componentEquipment, supplies, and technician only (no interpretation)
50Bilateral procedureSame procedure performed on both sides of the body
51Multiple proceduresMore than one procedure at the same session
52Reduced servicesA service partially reduced or eliminated at the provider's choice
53Discontinued procedureA procedure stopped after the patient's well-being became a concern
57Decision for surgeryThe E/M visit at which a major surgery decision was made
58Staged or related procedureA planned, staged, or more extensive related procedure in the global period
78Unplanned return to the ORA related procedure requiring a return to the operating room
79Unrelated procedure in the postop periodA procedure unrelated to the original surgery, within the global period
59Distinct procedural serviceA procedure distinct from another service on the same day
XE / XS / XP / XUSubsets of 59Separate encounter / separate structure / separate practitioner / unusual non-overlapping service
76Repeat procedure, same providerThe same provider repeats a procedure on the same day
77Repeat procedure, different providerA different provider repeats a procedure on the same day
91Repeat clinical diagnostic lab testA lab test repeated on the same day to obtain subsequent results

Component Modifiers: 26 and TC

Many diagnostic services — radiology in particular — split into two parts. The professional component (modifier 26) is the physician's interpretation and report. The technical component (modifier TC) covers the equipment, supplies, film, and technician. Billing a service with no split modifier reports the global service (both components). A biller appends 26 when the practice provides only the read, and TC when the practice owns only the equipment.

Same-Day E/M: 25 vs. 57

When an E/M visit happens the same day as a procedure, the biller must distinguish them. Modifier 25 marks a significant, separately identifiable E/M service performed alongside a minor procedure (0- or 10-day global). Modifier 57 marks the E/M visit at which the decision for major surgery (90-day global) was made, typically the day of or day before surgery.

Postoperative Relationships: 58, 78, 79

During a surgical global period, three modifiers describe what kind of follow-up service occurred:

  • 58 — a planned/staged or more extensive related procedure
  • 78 — an unplanned related return to the operating room for a complication
  • 79 — an unrelated procedure performed during the global period

Distinct Service: 59 and the X{EPSU} Modifiers

Modifier 59 identifies a distinct procedural service that is not normally reported together with another code — it can bypass certain bundling edits. CMS created four more specific alternatives: XE (separate encounter), XS (separate structure/organ), XP (separate practitioner), and XU (unusual, non-overlapping service). When one of the X modifiers fits, it is preferred over the broad 59.

Medicare ABN Modifiers: GA, GX, GY, GZ

These modifiers tie a claim to an Advance Beneficiary Notice of Noncoverage (ABN):

  • GA — a required ABN is on file; expected denial, patient may be billed.
  • GX — a voluntary ABN was issued for an item that is statutorily not covered.
  • GY — the item or service is statutorily excluded from Medicare; no ABN needed.
  • GZ — an ABN was not obtained and the service is expected to be denied; the provider may not bill the patient.
Test Your Knowledge

An imaging center owns the X-ray equipment and employs the technologist, but a separate radiology group reads and interprets every study. Which modifier should the imaging center append to the radiology codes it bills?

A
B
C
D
Test Your Knowledge

During the 90-day global period after a knee replacement, the surgeon performs an unplanned return to the operating room to treat a wound complication related to the original surgery. Which modifier applies?

A
B
C
D
Test Your Knowledge

A required Advance Beneficiary Notice of Noncoverage was signed by the Medicare patient because the service is likely to be denied as not medically necessary. Which modifier tells the payer the ABN is on file and the patient may be held liable?

A
B
C
D