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100+ Free Diploma in Genitourinary Medicine Practice Questions

Pass your Diploma in Genitourinary Medicine (DipGUM Apothecaries) exam on the first try — instant access, no signup required.

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Key Facts: Diploma in Genitourinary Medicine Exam

The Society of Apothecaries DipGUM examination comprises a 120-question, 180-minute online Best of Five (BO5) written paper and a 12-station clinical OSCE evaluating STI management, HIV medicine, genital dermatology, and sexual healthcare.

Sample Diploma in Genitourinary Medicine Practice Questions

Try these sample questions to test your Diploma in Genitourinary Medicine exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1A 22-year-old woman presents to a GUM clinic with post-coital bleeding and mucopurulent cervical discharge. Nucleic Acid Amplification Testing (NAAT) confirms Chlamydia trachomatis infection. She is not pregnant. According to BASHH guidelines, what is the first-line antibiotic treatment?
A.Doxycycline 100 mg orally twice daily for 7 days
B.Azithromycin 1 g orally as a single dose
C.Ceftriaxone 1 g IM as a single dose
D.Metronidazole 400 mg orally twice daily for 7 days
Explanation: Current BASHH guidelines specify Doxycycline 100 mg orally twice daily for 7 days as first-line treatment for uncomplicated genital Chlamydia trachomatis infection due to higher microbiological cure rates compared to single-dose azithromycin.
2A 25-year-old man presents with acute purulent urethral discharge and dysuria. Microscopy of urethral smear demonstrates Gram-negative intracellular diplococci. Culture and susceptibility testing are pending. According to BASHH guidelines, what is the recommended first-line empiric treatment for uncomplicated anogenital gonorrhoea when antimicrobial susceptibility is unknown?
A.Ceftriaxone 1 g IM as a single dose
B.Ciprofloxacin 500 mg orally as a single dose
C.Cefixime 400 mg orally as a single dose
D.Doxycycline 100 mg twice daily for 7 days
Explanation: BASHH guidelines recommend Ceftriaxone 1 g IM as a single dose for empiric treatment of uncomplicated Neisseria gonorrhoeae infection when antimicrobial sensitivities are unknown.
3A 30-year-old man presents with a single, painless, indurated ulcer on the glans penis accompanied by non-tender bilateral inguinal lymphadenopathy. Dark-field microscopy of ulcer exudate demonstrates motile treponemes. What is the first-line treatment for primary syphilis according to BASHH guidelines?
A.Benzathine benzylpenicillin 2.4 million units IM as a single dose
B.Doxycycline 100 mg orally twice daily for 28 days
C.Amoxicillin 500 mg orally three times daily for 7 days
D.Acyclovir 400 mg orally three times daily for 5 days
Explanation: Single-dose Benzathine benzylpenicillin 2.4 million units IM is the first-line treatment of choice for early (primary, secondary, or early latent) syphilis under BASHH guidelines.
4A 28-year-old man has persistent non-gonococcal urethritis (NGU) despite completing a 7-day course of doxycycline. NAAT testing is positive for Mycoplasma genitalium, and macrolide resistance testing demonstrates a 23S rRNA mutation (macrolide-resistant). What is the recommended second-line treatment according to BASHH guidelines?
A.Moxifloxacin 400 mg orally once daily for 7 days
B.Azithromycin 1 g followed by 500 mg daily for 2 days
C.Metronidazole 400 mg twice daily for 5 days
D.Ceftriaxone 1 g IM single dose
Explanation: BASHH guidelines specify that for macrolide-resistant Mycoplasma genitalium (or when macrolide resistance status is unknown), Moxifloxacin 400 mg once daily for 7 days is the recommended second-line treatment after initial doxycycline pre-treatment.
5A 29-year-old woman presents with a frothy yellow-green vaginal discharge, vulval pruritus, and a 'strawberry cervix' (punctate cervical haemorrhages) on speculum examination. Wet mount microscopy reveals flagellated motile protozoa. What is the first-line pharmacological treatment?
A.Metronidazole 400 mg orally twice daily for 7 days (or 2 g single dose)
B.Fluconazole 150 mg orally as a single dose
C.Clindamycin 2% vaginal cream for 7 days
D.Doxycycline 100 mg twice daily for 7 days
Explanation: Oral Metronidazole (400 mg twice daily for 7 days, or 2 g single dose) is the first-line treatment for Trichomonas vaginalis infection. Male partners must also be treated concurrently.
6A 21-year-old woman presents with severe vulval pain, dysuria, urinary retention, fever, and multiple bilateral painful ulcerated vesicles on the labia minora. Swab PCR confirms HSV-2. What is the recommended treatment for a first clinical episode of genital herpes under BASHH guidelines?
A.Aciclovir 400 mg orally three times daily for 5 days
B.Topical aciclovir 5% cream applied 5 times daily for 7 days
C.Oral valaciclovir 500 mg once daily for 12 months continuously
D.Intravenous ganciclovir 5 mg/kg for 14 days
Explanation: Under BASHH guidelines, first clinical episode of genital herpes is treated with oral Aciclovir 400 mg three times daily for 5 days (or Valaciclovir 500 mg twice daily for 5 days). Treatment should be started within 5 days of onset.
7A 24-year-old woman presents with bilateral lower abdominal pain, deep dyspareunia, abnormal vaginal bleeding, cervical motion tenderness ('excitation'), and adnexal tenderness on bimanual examination. Temperature is 38.3°C. According to BASHH guidelines, what is an recommended outpatient antibiotic regimen for acute Pelvic Inflammatory Disease (PID)?
A.Ceftriaxone 1 g IM single dose PLUS Doxycycline 100 mg twice daily PLUS Metronidazole 400 mg twice daily for 14 days
B.Amoxicillin 500 mg three times daily for 7 days
C.Single dose Azithromycin 1 g orally
D.Ciprofloxacin 500 mg twice daily for 5 days
Explanation: BASHH outpatient PID guidelines recommend a broad-spectrum combination covering N. gonorrhoeae, C. trachomatis, Mycoplasma, and anaerobes: Ceftriaxone 1 g IM single dose PLUS oral Doxycycline 100 mg twice daily for 14 days PLUS oral Metronidazole 400 mg twice daily for 14 days.
8A 22-year-old sexually active man presents with unilateral scrotal pain, swelling, epididymal tenderness, and fever. Urinalysis shows pyuria. In a sexually active man under 35 years without urinary tract instrumentation, what are the most common causative pathogens?
A.Chlamydia trachomatis and Neisseria gonorrhoeae
B.Escherichia coli and Pseudomonas aeruginosa
C.Enterococcus faecalis and Klebsiella pneumoniae
D.Ureaplasma urealyticum and Candida albicans
Explanation: In sexually active men under 35 years of age, acute epididymo-orchitis is predominantly caused by sexually transmitted pathogens: Chlamydia trachomatis and Neisseria gonorrhoeae. First-line treatment is Ceftriaxone 1 g IM plus Doxycycline 100 mg bd for 14 days.
9Six hours after receiving an intramuscular injection of Benzathine benzylpenicillin for secondary syphilis, a 28-year-old man develops sudden high fever, chills, myalgia, tachycardia, and temporary worsening of his cutaneous syphilitic roseola rash. What phenomenon has occurred?
A.Jarisch-Herxheimer reaction
B.Type 1 IgE-mediated anaphylactic reaction to penicillin
C.Stevens-Johnson syndrome
D.Serum sickness reaction
Explanation: The Jarisch-Herxheimer reaction is an acute self-limiting inflammatory reaction (fever, chills, headache, rash exacerbation) occurring within 2-24 hours of starting antitreponemal therapy, caused by mass release of endotoxin-like lipoproteins from dying Treponema pallidum. Treatment is supportive with antipyretics.
10Which set of findings satisfies Amsel's diagnostic criteria for Bacterial Vaginosis (requiring at least 3 of 4 features)?
A.Homogeneous thin greyish-white discharge, vaginal pH > 4.5, positive 10% KOH whiff test (fishy odour), and > 20% clue cells on wet mount microscopy
B.Curd-like white discharge, vaginal pH < 4.0, pseudohyphae on KOH mount, and intense vulval erythema
C.Frothy green discharge, vaginal pH > 5.5, mobile flagellated protozoa, and strawberry cervix
D.Purulent cervical discharge, cervical motion tenderness, pH 4.0, and Gram-negative diplococci
Explanation: Amsel's criteria for Bacterial Vaginosis require 3 of 4: (1) Thin homogeneous grey-white discharge; (2) Vaginal fluid pH > 4.5; (3) Positive amine 'whiff' test with 10% KOH; (4) Clue cells (vaginal epithelial cells studded with Gardnerella) comprising > 20% of epithelial cells on wet mount.

About the Diploma in Genitourinary Medicine Exam

The Diploma in Genitourinary Medicine (DipGUM), awarded by the Worshipful Society of Apothecaries, tests core clinical knowledge in sexually transmitted infections (STIs), HIV medicine, antiretroviral management, genital dermatology, and sexual/reproductive healthcare for medical practitioners and specialist trainees. Note: Practice questions provide an English MCQ study adaptation for the official assessment; it does not replace required writing, oral, portfolio, clinical, or hands-on performance.

Questions

120 scored questions

Time Limit

180 minutes

Passing Score

Angoff standard setting pass mark

Exam Fee

£1,150 (first-time entry, Bo5 + OSCE) (Worshipful Society of Apothecaries)

Diploma in Genitourinary Medicine Exam Content Outline

30%

Sexually Transmitted Infections (STIs)

Bacterial, viral, fungal, and parasitic STIs, PID, resistance, BASHH guidelines

25%

HIV Medicine & Antiretroviral Therapy

Primary HIV, ART regimens, opportunistic infections, PEP/PrEP guidelines

15%

Genital Dermatology & Non-Infectious Conditions

Lichen sclerosus, vulvodynia, VIN/PIN/AIN premalignant screening

15%

Sexual & Reproductive Health & Contraception

Emergency contraception, UKMEC guidelines, LARC, psychosexual health

15%

Medico-Legal, Ethics & Public Health

Confidentiality laws, safeguarding, sexual assault management, partner notification

How to Pass the Diploma in Genitourinary Medicine Exam

What You Need to Know

  • Passing score: Angoff standard setting pass mark
  • Exam length: 120 questions
  • Time limit: 180 minutes
  • Exam fee: £1,150 (first-time entry, Bo5 + OSCE)

Keys to Passing

  • Complete 500+ practice questions
  • Score 80%+ consistently before scheduling
  • Focus on highest-weighted sections
  • Use our AI tutor for tough concepts

Diploma in Genitourinary Medicine Study Tips from Top Performers

1Study current BASHH (British Association for Sexual Health and HIV) management guidelines for Chlamydia, Gonorrhoea, Syphilis, and Mycoplasma genitalium.
2Memorize BHIVA (British HIV Association) guidelines regarding ART regimen choices, CD4 thresholds, PCP prophylaxis, and PEP/PrEP prescribing.
3Review UKMEC (UK Medical Eligibility Criteria for Contraceptive Use) categories 1 to 4 and emergency contraception timeframes.
4Understand legal frameworks governing confidentiality in sexual health services (NHS Trusts Sexual Health Confidentiality regulations).

Frequently Asked Questions

What is the format of the DipGUM examination?

The examination comprises two independent components: a Best of Five (BO5) written paper (120 SBA questions in 3 hours online) and an in-person 12-station OSCE.

Who awards the Diploma in Genitourinary Medicine?

The DipGUM is awarded by the Worshipful Society of Apothecaries of London.

Which curriculum is the DipGUM blueprinted against?

The examination is blueprinted against the JRCPTB Genitourinary Medicine (GUM) Curriculum 2022.

Can the written and OSCE components be taken separately?

Yes. The written BO5 paper and OSCE are uncoupled and can be taken in any order or in different exam diets.

Does this practice bank replace clinical practice?

No. Our practice questions provide an English MCQ study adaptation for written BO5 preparation; they do not replace required clinical, practical, or hands-on performance training.