100+ Free ESENeph Practice Questions
Pass your European Specialty Examination in Nephrology exam on the first try — instant access, no signup required.
Muddy brown granular casts after hypotension most strongly suggest what AKI lesion?
Explore More UK Specialty Medicine Certificate Exams
Continue into nearby exams from the same family. Each card keeps practice questions, study guides, flashcards, videos, and articles in one place.
Key Facts: ESENeph Exam
9 Sep 2026
2026/01 ESENeph exam date
Federation ESENeph specialty page
200
Official exam questions
ESE regulations and ESENeph blueprint
2 x 3 hours
Paper timing
ESE regulations
GBP 700
UK exam fee
Federation ESENeph specialty page
30/200
Largest blueprint allocation
SCE in Nephrology blueprint
100
Free practice questions here
OpenExamPrep
The source row wording "SCE in Nephrology" is now normalized to ESENeph. The Federation lists ESENeph 2026/01 for 9 September 2026, with applications from 20 May to 17 June 2026, reasonable adjustment deadline 25 June 2026 and results six weeks after the exam. The exam has 200 best-of-five questions in two 3-hour computer-based papers, one mark per correct answer and no negative marking. Current fees are GBP 700 for UK candidates, EUR 800 for ESENeph full/associate/observer countries and GBP 875 for all other countries and territories.
Sample ESENeph Practice Questions
Try these sample questions to test your ESENeph exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.
1An adult with nephrotic syndrome has positive anti-PLA2R antibodies. What diagnosis is most likely?
2Rapidly progressive renal failure, haematuria, pulmonary symptoms and PR3-ANCA positivity suggest what biopsy pattern?
3Haemoptysis, rapidly progressive GN and anti-GBM antibodies require what urgent strategy?
4Diffuse proliferative lupus nephritis is usually induced with which treatment approach?
5Recurrent visible haematuria within 24 hours of upper respiratory infections most strongly suggests what diagnosis?
6Nephrotic syndrome after NSAID exposure with minimal change disease on biopsy should prompt what first step?
7HIV infection with heavy proteinuria and collapsing FSGS on biopsy is best managed by what core step?
8AKI with fever, rash and eosinophilia after a proton pump inhibitor suggests what diagnosis?
9Myeloma with severe AKI, high free light chains and bland dipstick most suggests what lesion?
10Persistent low C3 with C3-dominant glomerular staining suggests what condition?
About the ESENeph Exam
From February 2020, the former Specialty Certificate Examination in Nephrology and the European Certificate in Nephrology became the European Specialty Examination in Nephrology (ESENeph). The Federation states that ESENeph is the GMC-approved mandatory summative assessment of knowledge for UK trainees in Renal Medicine as part of CCT requirements. The examination uses best-of-five questions to test renal science and clinical judgement across glomerular disease, AKI, CKD, dialysis, transplantation, hypertension, urology, inherited kidney disease and supportive renal care.
Assessment
Computer-based European Specialty Examination in Nephrology with 200 best-of-five questions across two 3-hour papers. The published blueprint covers glomerulonephritis and tubulointerstitial nephritis, AKI and fluid/electrolyte/acid-base disorders, CKD, renal bone disease and anaemia, cardiovascular disease and hypertension, urological presentations, inherited and rarer diseases, peritoneal dialysis, haemodialysis, transplantation and other renal medicine topics.
Time Limit
Two 3-hour papers taken on the same day
Passing Score
Criterion-referenced standard setting; no fixed current percentage is listed on the reviewed current specialty page.
Exam Fee
UK: GBP 700; ESENeph full/associate/observer countries: EUR 800; all other countries and territories: GBP 875 (Federation of Royal Colleges of Physicians of the UK with ERA, the European Section and Board of Nephrology and the UK Kidney Association)
ESENeph Exam Content Outline
Glomerulonephritis and tubulointerstitial nephritis
Glomerular syndromes, vasculitis, anti-GBM disease, lupus nephritis, IgA nephropathy, nephrotic syndrome and drug-related interstitial nephritis.
AKI, renal replacement, fluid, electrolytes and acid-base
AKI recognition, obstruction, rhabdomyolysis, dialysis indications, hyperkalaemia, dysnatraemia, acidosis and safe correction.
CKD, haematuria and proteinuria
CKD staging and referral, albuminuria, haematuria evaluation, renoprotective therapy, cardiovascular risk and kidney failure planning.
Renal bone disease and renal anaemia
CKD-MBD, phosphate and PTH control, calciphylaxis, iron replacement, ESA safety and anaemia targets.
Cardiovascular disease, hypertension, renovascular disease and diabetes
Resistant hypertension, primary aldosteronism, renovascular disease, diabetic kidney disease, cardiorenal syndromes and nephrotic thrombotic risk.
Urological presentations
Stone disease, obstruction, infected hydronephrosis, haematuria, urinary tract infection and reflux nephropathy.
Inherited and rarer diseases
ADPKD, Alport syndrome, Fabry disease, atypical HUS, cystinuria, tuberous sclerosis and nephronophthisis.
Peritoneal dialysis
PD peritonitis, membrane transport, ultrafiltration failure, catheter issues and encapsulating peritoneal sclerosis.
Haemodialysis
Vascular access, adequacy, intradialytic hypotension, dialysis disequilibrium, infection and modality complications.
Renal transplantation
Acute rejection, immunosuppression toxicity, BK and CMV infection, PTLD, recurrent disease and HLA sensitisation.
Other renal medicine
Prescribing in CKD, pregnancy, infection in renal patients, active supportive care, nutrition, procedures, adult-paediatric interface and end-of-life care.
How to Pass the ESENeph Exam
What You Need to Know
- Passing score: Criterion-referenced standard setting; no fixed current percentage is listed on the reviewed current specialty page.
- Assessment: Computer-based European Specialty Examination in Nephrology with 200 best-of-five questions across two 3-hour papers. The published blueprint covers glomerulonephritis and tubulointerstitial nephritis, AKI and fluid/electrolyte/acid-base disorders, CKD, renal bone disease and anaemia, cardiovascular disease and hypertension, urological presentations, inherited and rarer diseases, peritoneal dialysis, haemodialysis, transplantation and other renal medicine topics.
- Time limit: Two 3-hour papers taken on the same day
- Exam fee: UK: GBP 700; ESENeph full/associate/observer countries: EUR 800; all other countries and territories: GBP 875
Keys to Passing
- Complete 500+ practice questions
- Score 80%+ consistently before scheduling
- Focus on highest-weighted sections
- Use our AI tutor for tough concepts
ESENeph Study Tips from Top Performers
Frequently Asked Questions
Is ESENeph the same as the old SCE in Nephrology?
From February 2020, the SCE in Nephrology and the European Certificate in Nephrology became a single examination called the European Specialty Examination in Nephrology (ESENeph).
When is ESENeph 2026/01?
The Federation lists ESENeph 2026/01 for 9 September 2026, with applications from 20 May to 17 June 2026 and the reasonable adjustment deadline on 25 June 2026.
What is the ESENeph format?
The ESE regulations state that each European specialty examination has two 3-hour computer-based papers, each containing 100 best-of-five questions.
What are the ESENeph fees?
The current Federation page lists GBP 700 for UK candidates, EUR 800 for candidates in ESENeph full/associate/observer countries, and GBP 875 for other countries and territories.
What blueprint areas are largest?
The largest published allocation is glomerulonephritis and tubulointerstitial nephritis at 30/200 questions, followed by AKI/fluid/electrolyte/acid-base at 26/200 and CKD/haematuria/proteinuria at 24/200.