100+ Free UNIKIN Medicine Admission Concours Practice Questions

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Key Facts: UNIKIN Medicine Admission Concours Exam

Flagship Medical School

DR Congo's oldest and most prestigious faculty of medicine

UNIKIN Faculty Council

5 subjects

Biology, chemistry, physics, mathematics and French announced for the medicine concours

Université de Kinshasa admission communications

16-17 Sept 2026

Dates fixed for the B1 concours of the Faculté de Médecine humaine, 2026-2027 intake

Université de Kinshasa concours calendar

USD 30

Concours participation fee in CDF equivalent for Médecine humaine, on top of CDF 150,000 registration

Université de Kinshasa 2026-2027 enrolment notice

Free 100-question practice bank for the UNIKIN Faculté de Médecine Admission Concours (DR Congo). Covers medical biology, chemistry, biophysics, biostatistics, and scientific French medical reasoning with full explanations.

Sample UNIKIN Medicine Admission Concours Practice Questions

Try these sample questions to test your UNIKIN Medicine Admission Concours exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1Which organelle is primarily responsible for generating the majority of cellular ATP via oxidative phosphorylation in eukaryotic human cells?

A.Rough endoplasmic reticulum

B.Mitochondrion

C.Golgi apparatus

D.Peroxisome

Explanation: Mitochondria generate over 90% of cellular ATP in aerobic human cells through the electron transport chain and ATP synthase located on the inner mitochondrial membrane (cristae). Pyruvate oxidation, the Krebs cycle, and beta-oxidation occur within the mitochondrial matrix to feed high-energy electron carriers (NADH and FADH2) into oxidative phosphorylation.

2Lysosomes maintain an internal acidic environment (pH ~4.5–5.0) optimal for acid hydrolases through which active transport mechanism?

A.Vacuolar-type H+-ATPase (V-ATPase) proton pump

B.Sodium-potassium ATPase (Na+/K+-ATPase)

C.Calcium ATPase (SERCA pump)

D.Glucose-sodium symporter (SGLT1)

Explanation: Lysosomes utilize a transmembrane Vacuolar H+-ATPase (V-ATPase) that hydrolyzes cytosolic ATP to actively pump protons (H+) against their concentration gradient into the lysosomal lumen. This maintains the acidic pH (~4.5–5.0) required for optimal catalytic activity of over 50 acidic hydrolases (proteases, nucleases, lipases) while preventing accidental autolysis of the neutral cytoplasm (pH ~7.2).

3According to the fluid mosaic model of biological membranes, how does cholesterol modulate plasma membrane fluidity at physiological vs low temperatures?

A.It completely immobilizes phospholipids at high temperatures and promotes crystallization at low temperatures

B.It restricts phospholipid acyl chain mobility at elevated temperatures and prevents dense hydrocarbon packing at low temperatures

C.It converts the lipid bilayer into a rigid, non-fluid crystalline gel across all physiological temperatures

D.It increases the permeability of the membrane to small polar ions and water molecules at all temperatures

Explanation: Cholesterol acts as a bidirectional membrane fluidity buffer. At physiological and warm temperatures (~37°C), its rigid steroid ring intercalates between fatty acyl chains, restricting their lateral movement and stabilizing the bilayer; at low temperatures, it prevents fatty acid tails from packing closely into an ordered crystalline gel, thereby preserving fluidity.

4The plasma membrane sodium-potassium pump (Na+/K+-ATPase) operates with which precise ionic stoichiometry and electrogenic result per hydrolyzed ATP molecule?

A.Transports 2 Na+ ions out of the cell and 3 K+ ions in, generating an intracellular positive charge

B.Transports 3 Na+ ions out of the cell and 2 K+ ions in, generating an intracellular net negative current

C.Transports 3 Na+ ions into the cell and 3 K+ ions out, maintaining electroneutrality

D.Transports 1 Na+ ion out of the cell and 1 K+ ion in, with no net current generation

Explanation: The Na+/K+-ATPase is an electrogenic P-type ATPase that exports 3 Na+ ions from the cytoplasm to the extracellular fluid and imports 2 K+ ions into the cytoplasm for each molecule of ATP hydrolyzed. Because there is a net outward movement of one positive charge per cycle, the pump contributes directly to the negative resting membrane potential (generating ~-5 to -10 mV) and maintains the steep electrochemical gradients vital for secondary active transport and nerve excitability.

5During which phase of somatic cell division (mitosis) are sister chromatids aligned along the equatorial plane under the surveillance of the spindle assembly checkpoint?

A.Prophase

B.Metaphase

C.Anaphase

D.Telophase

Explanation: During metaphase, condensed chromosomes align along the central equatorial (metaphase) plate. The spindle assembly checkpoint (SAC) monitors bipolar kinetochore tension and microtubule attachment; once every kinetochore is properly attached to spindle fibers from opposite poles, the anaphase-promoting complex (APC/C) is activated to initiate sister chromatid separation.

6During human gametogenesis, in which substage of Prophase I does genetic recombination (crossing over) occur between non-sister chromatids of homologous chromosomes?

A.Leptotene

B.Zygotene

C.Pachytene

D.Diplotene

Explanation: Crossing over (homologous genetic recombination) takes place during the pachytene substage of meiotic prophase I. Once homologous chromosomes are fully paired along their length by the synaptonemal complex (formed during zygotene), recombination nodules mediate the reciprocal exchange of DNA segments between non-sister chromatids.

7What is the primary cytogenetic mechanism responsible for standard trisomy 21 (Down syndrome) in over 90% of documented clinical cases?

A.Maternal meiotic nondisjunction of chromosome 21

B.Balanced reciprocal translocation between chromosomes 9 and 22

C.Robertsonian translocation rob(14;21) inherited from an asymptomatic father

D.Mitotic gene amplification on the long arm of chromosome 21

Explanation: Over 90–95% of Down syndrome cases result from maternal meiotic nondisjunction of chromosome 21 (most commonly during Meiosis I in maternal oocytes), leading to an egg with two copies of chromosome 21. Fertilization by a normal sperm results in free trisomy 21 (47,XX,+21 or 47,XY,+21). The risk increases exponentially with advanced maternal age due to degrading meiotic cohesin complexes.

8During DNA replication in human cells, which enzyme synthesizes the short RNA primer required to provide a free 3'-hydroxyl (-OH) group for DNA polymerase?

A.DNA Ligase

B.DNA Helicase

C.RNA Primase

D.Topoisomerase II

Explanation: DNA polymerases cannot initiate de novo DNA synthesis because they require a pre-existing 3'-OH group to form a phosphodiester bond. RNA Primase (a DNA-dependent RNA polymerase) synthesizes a short complementary RNA primer (~10 nucleotides) that provides the necessary 3'-OH terminus for DNA polymerase extension on both leading and lagging strands.

9Which post-transcriptional modification of eukaryotic pre-mRNA involves the removal of non-coding intervening sequences by the spliceosome complex?

A.5' 7-methylguanosine capping

B.3' polyadenylation

C.Intron splicing

D.RNA editing by cytidine deaminase

Explanation: Intron splicing is the precise excision of non-coding intervening sequences (introns) from eukaryotic pre-mRNA and the subsequent ligation of coding sequences (exons). This process is catalyzed by the spliceosome, a dynamic macromolecular complex of small nuclear ribonucleoproteins (snRNPs U1, U2, U4, U5, U6) recognizing conserved 5' donor (GU), branch point (A), and 3' acceptor (AG) consensus sites.

10What is the molecular genetic term for a single-nucleotide substitution that alters a codon to encode a premature stop codon (UAA, UAG, or UGA)?

A.Silent (synonymous) mutation

B.Missense mutation

C.Nonsense mutation

D.Frameshift mutation

Explanation: A nonsense mutation is a point mutation in a DNA sequence that results in a premature termination (stop) codon in the transcribed mRNA (UAA, UAG, or UGA). This leads to premature termination of peptide chain translation, typically producing a truncated, non-functional protein that is often degraded via nonsense-mediated mRNA decay.

About the UNIKIN Medicine Admission Concours Exam

The Faculté de Médecine at the Université de Kinshasa (UNIKIN) is the most prestigious and historic medical school in the Democratic Republic of the Congo. Admission to the first-year medical program (B1 Médecine / Premier Graduat) is governed by a rigorous and highly selective annual Concours d'Admission. The exam evaluates candidates on advanced high school and pre-med foundational disciplines: Medical Biology (cytology, genetics, human physiology, parasitology), General and Organic Chemistry (biomolecules, thermodynamics, buffer solutions), Biophysics (hemodynamics, medical optics, ionizing radiation), Applied Mathematics and Biostatistics (dosages, probability, epidemiological rates), and Scientific French (medical terminology and comprehension). This free English MCQ practice bank offers 100 substantive, research-grounded questions with comprehensive step-by-step rationales.

Assessment

Two days of written papers organised by the Faculté de Médecine itself, on its own calendar slot separate from the other UNIKIN faculties (16-17 September 2026 for the 2026-2027 B1 intake, with the Master 1 concours on 14-15 September). UNIKIN announces the subjects examined — biologie, chimie, physique, mathématiques and French — but not how they are distributed across the two days.

Time Limit

Two days; the 2026-2027 B1 concours for the Faculté de Médecine humaine was set for 16 and 17 September 2026

Passing Score

Not published — the faculty publishes a list of admissibles after each concours and admits against its intake quota; no fixed cut-off mark is announced

Exam Fee

Concours participation fee for Médecine humaine: the equivalent of USD 30 in Congolese francs, plus CDF 150,000 registration (UNIKIN 2026-2027 notice) (Université de Kinshasa (UNIKIN) — Faculté de Médecine)

UNIKIN Medicine Admission Concours Exam Content Outline

Study emphasis ~30%

Medical Biology & Cytogenetics

Cellular ultrastructure, membrane transport, mitosis and meiosis, nucleic acids, human organ systems (circulatory, nervous, respiratory, endocrine), and tropical infectious diseases (malaria, trypanosomiasis, schistosomiasis, viral hemorrhagic fevers).

Study emphasis ~25%

General & Organic Chemistry

Atomic structure, chemical bonding, solution concentrations, acid-base equilibria, physiological buffer systems, chemical thermodynamics, organic reaction mechanisms, carbohydrates, lipids, amino acids, and enzyme kinetics.

Study emphasis ~20%

Biophysics & Medical Physics

Fluid dynamics, Poiseuille's law, blood pressure mechanics, geometrical and corrective optics, wave optics, resting and action membrane potentials (Nernst equation), and ionizing radiation physics.

Study emphasis ~15%

Applied Mathematics & Biostatistics

Dosage calculations, pharmacokinetic exponential decay, probability rules, normal distributions, diagnostic accuracy metrics (sensitivity, specificity, PPV, NPV), and epidemiological measures (prevalence, incidence, odds ratios).

Study emphasis ~10%

Scientific French & Medical Reasoning

Greco-Latin medical etymology, clinical reasoning and deductive logic, and comprehension of biomedical research and diagnostic case vignettes.

How to Pass the UNIKIN Medicine Admission Concours Exam

What You Need to Know

Passing score: Not published — the faculty publishes a list of admissibles after each concours and admits against its intake quota; no fixed cut-off mark is announced
Assessment: Two days of written papers organised by the Faculté de Médecine itself, on its own calendar slot separate from the other UNIKIN faculties (16-17 September 2026 for the 2026-2027 B1 intake, with the Master 1 concours on 14-15 September). UNIKIN announces the subjects examined — biologie, chimie, physique, mathématiques and French — but not how they are distributed across the two days.
Time limit: Two days; the 2026-2027 B1 concours for the Faculté de Médecine humaine was set for 16 and 17 September 2026
Exam fee: Concours participation fee for Médecine humaine: the equivalent of USD 30 in Congolese francs, plus CDF 150,000 registration (UNIKIN 2026-2027 notice)

Keys to Passing

Work through all 100 available questions
Review every answer and explanation
Track weak areas and revisit them
Use our AI tutor for tough concepts

UNIKIN Medicine Admission Concours Study Tips from Top Performers

1Prioritize high-yield tropical parasitology (Plasmodium, Trypanosoma, Schistosoma) and physiological mechanisms (action potentials, cardiac cycle, acid-base homeostasis).

2Practice rapid calculations for Henderson-Hasselbalch buffer equations, Michaelis-Menten kinetics, and dilution/dosage problems without relying on advanced graphing calculators.

3Master biophysics formulas: Poiseuille's law for vascular resistance, lens equation for vision correction, and Nernst equation for equilibrium membrane potentials.

4Review biostatistical calculations for diagnostic 2x2 contingency tables: sensitivity, specificity, positive predictive value, negative predictive value, and odds ratios.

5Familiarize yourself with medical Greek and Latin roots and scientific French vocabulary to excel in terminology and reading comprehension questions.

Frequently Asked Questions

What is the UNIKIN Faculté de Médecine Concours d'Admission?

It is the entrance competition for the first year of medical studies (B1) at the Université de Kinshasa, run by the Faculté de Médecine on its own calendar and covering the biomedical, dentistry and medicine intakes. UNIKIN's enrolment notice lists Médecine — with Médecine Dentaire, Polytechnique and the Mathematics-Computer Science department — among the faculties where the concours is compulsory for every applicant, whatever their EXETAT percentage.

What subjects are tested on the UNIKIN Medicine Concours?

The examination tests five core subjects: Biologie (Biology & Parasitology), Chimie (General & Organic Chemistry), Physique (Biophysics & Medical Physics), Mathématiques & Biostatistiques (Applied Mathematics), and Français (Scientific French & Medical Reasoning).

What is the official format and language of the exam?

The official examination is written and sat in French. This bank is an English-language multiple-choice study adaptation: it rehearses the same biology, chemistry, physics, mathematics and scientific-French reasoning, but it is not an official translation and it does not reproduce the official paper format, which UNIKIN does not publish.

What score is needed to be admitted?

UNIKIN does not publish a fixed cut-off for this concours. The faculty releases a list of admissibles after the papers are marked and admits against the intake quota it has opened, so the effective threshold moves each year with the size and strength of the candidate field.

Who is eligible to sit for the concours?

Holders of the Congolese Diplôme d'État (EXETAT) — predominantly from the Bio-Chimie and Math-Physique sections — or equivalent international secondary school leaving credentials.