100+ Free EXETAT Chimie-Biologie Practice Questions

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2026 Statistics

Key Facts: EXETAT Chimie-Biologie Exam

50%

Minimum composite percentage required to earn the Diplôme d'État

EDU-NC National Examination Regulations

4 days

Length of the EXETAT session ordinaire, held 22-25 June in 2026

Direction des Examens d'État (EDU-NC)

1,079,675

Cycle-long candidates registered for the 2026 EXETAT session

Ministère de l'Éducation Nationale et Nouvelle Citoyenneté

60%+

EXETAT mark that exempts a holder from the UNIKIN and UNILU admission tests

DR Congo Higher Education Guidance

QCM

Standard multiple-choice format with optical scan answer sheets

EDU-NC EXETAT Technical Framework

Free 100-question English MCQ practice bank for DR Congo EXETAT Option Chimie-Biologie. Official exam: 4-day French QCM session administered by EDU-NC; 50% pass threshold for Diplôme d'État, 60%+ for unrestricted university matriculation.

Sample EXETAT Chimie-Biologie Practice Questions

Try these sample questions to test your EXETAT Chimie-Biologie exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1According to the fluid mosaic model proposed by Singer and Nicolson, what is the fundamental structural organization of the eukaryotic plasma membrane?

A.A rigid monolayer of carbohydrates with embedded structural proteins

B.A phospholipid bilayer with hydrophilic heads facing outwards and hydrophobic fatty acid tails facing inwards, interspersed with proteins

C.A triple layer of globular proteins enclosing a central core of neutral triglycerides

D.A solid shell of cellulose microfibrils enclosing transmembrane transport channels

Explanation: The fluid mosaic model describes the plasma membrane as a dynamic phospholipid bilayer. The polar hydrophilic phosphate heads orient toward the aqueous intracellular and extracellular environments, while the non-polar hydrophobic hydrocarbon tails face inward toward each other. Integral and peripheral proteins are embedded within or attached to this fluid matrix.

2Which eukaryotic organelle contains acid hydrolases responsible for intracellular digestion of macromolecules, autophagy of worn-out organelles, and phagocytosed pathogens?

A.Peroxisome

B.Lysosome

C.Centrosome

D.Ribosome

Explanation: Lysosomes are membrane-bound digestive vesicles containing over 50 different acid hydrolases (such as proteases, nucleases, and lipases) that function optimally at an acidic pH of ~4.5–5.0. They are responsible for cellular waste breakdown, autophagy, and heterophagy. The acidic lumen is maintained by active proton-pumping V-type ATPases in the lysosomal membrane.

3In eukaryotic secretory pathways, newly synthesized proteins destined for secretion travel from the rough endoplasmic reticulum (RER) to which face of the Golgi apparatus?

A.The cis face (forming face)

B.The trans face (maturing face)

C.The medial cristae

D.The outer nuclear pore complex

Explanation: Transport vesicles budding from the rough endoplasmic reticulum fuse with the cis face (entry or forming face) of the Golgi apparatus. Proteins undergo post-translational modifications (such as glycosylation and phosphorylation) as they progress through the medial cisternae before exiting from the trans face (maturing face) in secretory vesicles.

4During the complete anaerobic breakdown of one mole of glucose via glycolysis in the cytoplasm, what is the net yield of ATP and reduced coenzyme NADH per glucose molecule?

A.4 ATP (net) and 2 NADH

B.2 ATP (net) and 2 NADH

C.2 ATP (net) and 4 NADH

D.36 ATP (net) and 0 NADH

Explanation: Glycolysis consumes 2 ATP in its preparatory/investment phase (catalyzed by hexokinase and phosphofructokinase-1) and produces 4 ATP in the payoff phase via substrate-level phosphorylation, resulting in a net yield of 2 ATP. In addition, 2 molecules of NAD+ are reduced to 2 NADH by glyceraldehyde-3-phosphate dehydrogenase.

5In which exact mitochondrial compartment does the Krebs (citric acid) cycle take place in eukaryotic cells?

A.Inner mitochondrial membrane

B.Intermembrane space

C.Mitochondrial matrix

D.Outer mitochondrial membrane

Explanation: The enzymes of the citric acid cycle (Krebs cycle) are soluble proteins located in the mitochondrial matrix, where acetyl-CoA is oxidized to CO2. The only exception is succinate dehydrogenase, which is an integral enzyme embedded in the inner mitochondrial membrane (functioning as Complex II of the electron transport chain).

6According to Mitchell's chemiosmotic hypothesis, what immediately drives the synthesis of ATP by ATP synthase during oxidative phosphorylation?

A.Direct transfer of a high-energy phosphate group from succinyl-CoA

B.The electrochemical proton gradient (proton-motive force) across the inner mitochondrial membrane

C.The passive flow of sodium ions across the outer mitochondrial membrane

D.The direct hydrolysis of GTP in the cytoplasm

Explanation: As electrons flow through Complexes I, III, and IV of the mitochondrial electron transport chain, protons (H+) are actively pumped from the matrix into the intermembrane space. This creates an electrochemical proton gradient (proton-motive force). Protons flow back into the matrix down their gradient through the F0 rotor of ATP synthase, driving rotational catalysis in F1 to synthesize ATP from ADP and Pi.

7During the light-dependent reactions of oxygenic photosynthesis in chloroplasts, photolysis of water occurs at which specific photosystem complex?

A.Photosystem I (P700) on the stroma-facing lamellae

B.Photosystem II (P680) on the lumenal side of the thylakoid membrane

C.Cytochrome b6f complex in the stroma

D.ATP synthase CF1-CF0 complex in the outer chloroplast envelope

Explanation: Photolysis of water (2 H2O -> O2 + 4 H+ + 4 e-) is catalyzed by the oxygen-evolving manganese-calcium complex (OEC) associated with Photosystem II (P680) on the lumenal face of the thylakoid membrane. The released electrons replace those excited and transferred from P680, protons contribute to the thylakoid lumen proton gradient, and molecular oxygen (O2) is released as a byproduct.

8Which key enzyme in the stroma of chloroplasts catalyzes the fixation of atmospheric carbon dioxide (CO2) onto ribulose-1,5-bisphosphate (RuBP) in the Calvin cycle?

A.Phosphoenolpyruvate carboxylase (PEP carboxylase)

B.Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO)

C.Pyruvate dehydrogenase

D.Phosphofructokinase

Explanation: RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) is the primary enzyme of the Calvin-Benson cycle in C3 plants. It catalyzes the carboxylation of the 5-carbon acceptor ribulose-1,5-bisphosphate (RuBP) with CO2 to form an unstable 6-carbon intermediate that immediately cleaves into two molecules of 3-phosphoglycerate (3-PGA).

9During DNA replication in prokaryotes, which enzyme removes RNA primers and replaces them with deoxyribonucleotides, and which enzyme seals the remaining nick in the phosphodiester backbone?

A.DNA polymerase III removes primers; Helicase seals the nick

B.DNA polymerase I removes primers; DNA ligase seals the nick

C.RNA primase removes primers; Topoisomerase seals the nick

D.DNA polymerase II removes primers; Telomerase seals the nick

Explanation: DNA polymerase I possesses 5'-to-3' exonuclease activity that excises the RNA primers on the lagging strand (and leading strand origin) while simultaneously filling the resulting gap with DNA nucleotides using its 5'-to-3' polymerase activity. DNA ligase then catalyzes the formation of a phosphodiester bond between the adjacent 3'-OH and 5'-phosphate groups, sealing the nick.

10If a template DNA strand has the base sequence 3'-TAC GGC TTA CGA ATT-5', what will be the base sequence of the mRNA transcribed from this sequence?

A.5'-AUG CCG AAU GCU UAA-3'

B.5'-ATG CCG AAT GCT TAA-3'

C.5'-UAC GGC UUA CGA AUU-3'

D.5'-AUG CCG UUA GCU UAA-3'

Explanation: Transcription produces an antiparallel, complementary RNA strand from the 3'-to-5' DNA template strand using ribonucleotides (with Uracil replacing Thymine). Complementary pairing: 3'-T->5'-A, 3'-A->5'-U, 3'-C->5'-G, 3'-G->5'-C, 3'-G->5'-C, 3'-C->5'-G, 3'-T->5'-A, 3'-T->5'-A, 3'-A->5'-U, 3'-C->5'-G, 3'-G->5'-C, 3'-A->5'-U, 3'-A->5'-U, 3'-T->5'-A, 3'-T->5'-A yields 5'-AUG CCG AAU GCU UAA-3'.

About the EXETAT Chimie-Biologie Exam

The Examen d'État (EXETAT) is the national secondary school-leaving and university entrance examination in the Democratic Republic of the Congo. Administered by the Ministère de l'Éducation Nationale et Nouvelle Citoyenneté (EDU-NC), the Option Chimie-Biologie (Humanités Scientifiques) track is the standard pathway for students pursuing higher education in medicine, pharmacy, biochemistry, agronomy, biomedical engineering, and environmental sciences. The national session tests candidates using optical bubble sheets (QCM) across four days. This practice bank provides 100 rigorous multiple-choice questions with thorough step-by-step explanations.

Assessment

Hors-session tests in May (dissertation, traditional papers for the technical options, oral French and — new from the 2026 session — oral English, and professional practice), followed by the four-day session ordinaire: Day 1 Culture générale, Day 2 Sciences, Day 3 Options, Day 4 Langues.

Time Limit

Four-day written session (22–25 June for the 2026 edition), preceded by hors-session tests in May; each épreuve booklet carries its own duration, typically 2 to 5 hours

Passing Score

50% overall for the Diplôme d'État; 60% or more exempts the holder from the admission tests run by universities such as UNIKIN and UNILU

Exam Fee

Fixed per province by governor's decree, not nationally: for the 2026 session the hors-session fee ranged from about CDF 52,000 to CDF 100,000 and the session ordinaire fee from about CDF 40,000 to CDF 90,000 (Kinshasa: CDF 80,000 + CDF 60,000). Candidates in Nord-Kivu and Sud-Kivu were exempted by the government. (Ministère de l'Éducation Nationale et Nouvelle Citoyenneté (EDU-NC))

EXETAT Chimie-Biologie Exam Content Outline

Study emphasis ~35%

Biology (Biologie)

Cytology and ultrastructure, cellular energetics (glycolysis, Krebs cycle, photosynthesis), molecular genetics (DNA replication, transcription, translation), Mendelian inheritance, human physiology, organ systems, botany, and regional ecology.

Study emphasis ~30%

Chemistry (Chimie)

Atomic orbital theory, chemical equilibrium (Le Chatelier's principle, Kc/Kp), pH calculations, buffer systems, redox potentials, galvanic cells, and functional organic chemistry (alkanes, alkenes, alcohols, carbonyls, carboxylic acids, esters, amines, carbohydrates, and lipids).

Study emphasis ~15%

Physics (Physique)

Newtonian mechanics, work-energy theorem, fluid hydrostatics, electrostatic fields, Coulomb's law, direct current circuits, magnetic induction, geometrical optics, thin lens equations, and thermodynamics.

Study emphasis ~10%

Mathematics (Mathématiques)

Real-valued functions, polynomial and rational limits, derivatives, curves analysis, indefinite and definite integrals, trigonometric identities, combinatorics, and discrete probability distributions.

Study emphasis ~10%

General Culture & Civics (Culture Générale)

Geography and hydrography of the Democratic Republic of the Congo (Congo River basin, mineral provinces), political history (independence 1960, major historical figures), constitutional institutions of the Third Republic, civic morality, and scientific terminology.

How to Pass the EXETAT Chimie-Biologie Exam

What You Need to Know

Passing score: 50% overall for the Diplôme d'État; 60% or more exempts the holder from the admission tests run by universities such as UNIKIN and UNILU
Assessment: Hors-session tests in May (dissertation, traditional papers for the technical options, oral French and — new from the 2026 session — oral English, and professional practice), followed by the four-day session ordinaire: Day 1 Culture générale, Day 2 Sciences, Day 3 Options, Day 4 Langues.
Time limit: Four-day written session (22–25 June for the 2026 edition), preceded by hors-session tests in May; each épreuve booklet carries its own duration, typically 2 to 5 hours
Exam fee: Fixed per province by governor's decree, not nationally: for the 2026 session the hors-session fee ranged from about CDF 52,000 to CDF 100,000 and the session ordinaire fee from about CDF 40,000 to CDF 90,000 (Kinshasa: CDF 80,000 + CDF 60,000). Candidates in Nord-Kivu and Sud-Kivu were exempted by the government.

Keys to Passing

Work through all 100 available questions
Review every answer and explanation
Track weak areas and revisit them
Use our AI tutor for tough concepts

EXETAT Chimie-Biologie Study Tips from Top Performers

1Master biological pathways (cellular respiration, photosynthesis, protein synthesis) and practice tracing molecular intermediates.

2Review organic reaction mechanisms and IUPAC nomenclature for oxygenated and nitrogenous functional groups.

3Practice multi-step numerical calculations in stoichiometry, chemical equilibria, pH titrations, and Newtonian mechanics without a calculator.

4Consolidate core facts regarding Congolese physical geography, national hydrography, provincial administrative divisions, and modern history.

Frequently Asked Questions

What is the Examen d'État (EXETAT) in the Democratic Republic of the Congo?

The EXETAT is the mandatory national examination administered at the end of secondary education (6ème Humanités) by the Ministère de l'Éducation Nationale et Nouvelle Citoyenneté (EDU-NC). Passing the EXETAT awards the Diplôme d'État, certifying secondary completion and qualifying students for higher education.

What subjects are tested in the Option Chimie-Biologie?

Candidates in the Chimie-Biologie stream are tested across four days on Biology, Chemistry, Physics, Mathematics, French language, and General Culture (encompassing Congolese history, geography, and civic morality). Preliminary tests also assess French dissertation writing and practical laboratory/scientific demonstrations.

How is the EXETAT scored and what is the passing mark?

The examination is scored on a percentage scale out of 100%. A composite score of at least 50% is required to obtain the Diplôme d'État. Scores of 60% or higher ('lauréat') generally permit direct admission to premier public universities and faculties of medicine and pharmacy.

What format does the official national examination use?

The standard session uses paper-based multiple-choice questionnaires (QCM) evaluated via optical scanning sheets (grilles de réponses optiques). The preliminary 'hors-session' includes a written dissertation essay and oral/practical evaluations.

Is this practice question bank an official examination paper?

No. This practice bank is an independent English-language educational adaptation designed to reinforce essential concepts in science, mathematics, and Congolese general culture aligned with the national curriculum.