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100+ Free PEBC Part I (MCQ) Practice Questions

PEBC Pharmacist Qualifying Examination Part I (Multiple-Choice Question exam) practice questions are available now; exam metadata is being verified.

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2026 Statistics

Key Facts: PEBC Part I (MCQ) Exam

About 4.5 hours

Single-day computer-based testing time at Prometric for Part I (MCQ)

PEBC - Pharmacist Qualifying Examination

6 competencies

Part I blueprint follows the six 2024 NAPRA entry-to-practice competencies

PEBC - Qualifying Examination Blueprint

About 50%

Providing Care: Clinical Care is the highest-weighted competency area

PEBC - Qualifying Examination Blueprint

CAD $855

2026 PEBC fee for the Pharmacist Qualifying Examination - Part I (MCQ)

PEBC - Examination Dates and Fees

Criterion-referenced

No fixed pass percentage; an expert panel sets a standardized cut score

PEBC - Examination Scoring and Results

Standalone and case-based

MCQ items mix standalone questions with case-based clusters plus unscored pretest items

PEBC - Frequently Asked Questions

About 86%

Canadian reference graduates' first-time pass rate (2021-2023 administrations)

PEBC - Examination Scoring and Results

100

Free original practice questions in this bank

OpenExamPrep

The PEBC Pharmacist Qualifying Examination - Part I (MCQ) is the multiple-choice part of Canada's national pharmacist licensing exam, delivered on computer at Prometric in about 4.5 hours. It is built to a blueprint from the 2024 NAPRA entry-to-practice competencies: Clinical Care is weighted around 50%, Product Distribution around 20%, Professionalism around 12%, Knowledge and Expertise around 11%, Communication and Education around 4%, and Leadership and Stewardship around 3%. The exam is criterion-referenced with no published pass percentage; a subject-matter expert panel sets the cut score and results are standardized across administrations. The 2026 fee is CAD $855, and the exam blends standalone and case-based questions plus unscored pretest items. This 100-question bank provides original practice modelled on the blueprint, emphasizing Canadian therapeutics, pharmaceutical calculations, drug distribution, law and ethics.

Sample PEBC Part I (MCQ) Practice Questions

Try these sample questions to test your PEBC Part I (MCQ) exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1A 58-year-old man with newly diagnosed hypertension and type 2 diabetes (eGFR 70 mL/min, urine albumin-to-creatinine ratio elevated) needs first-line antihypertensive therapy. Which class is most appropriate to start?
A.Thiazide diuretic
B.ACE inhibitor
C.Non-dihydropyridine calcium channel blocker
D.Alpha-blocker
Explanation: In a patient with diabetes and albuminuria, an ACE inhibitor (or ARB) is preferred first-line because it lowers blood pressure and provides renal protection by reducing intraglomerular pressure and albuminuria. Hypertension Canada and Diabetes Canada guidelines recommend ACEi/ARB in this setting.
2A 64-year-old woman with type 2 diabetes and established atherosclerotic cardiovascular disease has an A1C of 8.2% on metformin. Which add-on agent best reduces cardiovascular risk per current Diabetes Canada guidance?
A.Glyburide
B.An SGLT2 inhibitor or GLP-1 receptor agonist with proven CV benefit
C.A DPP-4 inhibitor
D.Acarbose
Explanation: For people with type 2 diabetes and clinical cardiovascular disease, Diabetes Canada recommends adding an SGLT2 inhibitor or GLP-1 receptor agonist with demonstrated cardiovascular benefit, independent of A1C target, because these agents reduce major adverse cardiovascular events.
3A patient starting atorvastatin asks which symptom would most warrant contacting a health professional promptly. Which should the pharmacist counsel on?
A.Mild headache on the first day
B.Unexplained muscle pain with dark urine
C.A metallic taste
D.Occasional mild constipation
Explanation: Unexplained muscle pain or weakness with dark (tea-coloured) urine can signal rhabdomyolysis, a rare but serious statin adverse effect that requires prompt medical assessment and creatine kinase testing. Patients should be told to report these symptoms.
4A 72-year-old patient with atrial fibrillation, CHADS-65 positive, and an eGFR of 55 mL/min is to start anticoagulation. Which is generally preferred over warfarin for non-valvular AF in Canadian guidance?
A.A direct oral anticoagulant (DOAC)
B.Aspirin 81 mg daily
C.Low-dose unfractionated heparin
D.Clopidogrel
Explanation: For most patients with non-valvular atrial fibrillation requiring anticoagulation, CCS guidelines recommend a DOAC over warfarin because of comparable or superior stroke prevention with lower intracranial bleeding risk and no routine INR monitoring. Dose is adjusted for renal function.
5A patient with asthma uses a salbutamol inhaler more than 4 times per week and wakes at night with symptoms twice a month. According to current asthma management, what change is most appropriate?
A.Continue salbutamol alone as needed
B.Add or optimize inhaled corticosteroid-containing controller therapy
C.Switch to oral prednisone daily
D.Add a long-acting muscarinic antagonist as monotherapy
Explanation: Frequent reliever use and nighttime symptoms indicate inadequate control. Current asthma guidance emphasizes inhaled corticosteroid-containing therapy (ICS or ICS-formoterol) as the controller foundation rather than relying on a short-acting beta-agonist alone.
6A 40-year-old woman with an uncomplicated lower urinary tract infection has no allergies and normal renal function. Which is a recommended first-line empiric option in Canada?
A.Ciprofloxacin
B.Nitrofurantoin
C.Amoxicillin
D.Azithromycin
Explanation: Nitrofurantoin is a preferred first-line agent for uncomplicated cystitis in non-pregnant adults with adequate renal function because of high efficacy and low collateral resistance. Fluoroquinolones are reserved due to resistance and adverse-effect concerns.
7A patient is starting sertraline for major depressive disorder. Which counselling point about onset of effect is most accurate?
A.Mood usually improves fully within 2 days
B.Full antidepressant effect may take 4 to 6 weeks
C.It works only if taken at the first sign of low mood
D.It should be stopped abruptly once mood improves
Explanation: SSRIs such as sertraline typically require 4 to 6 weeks for full antidepressant effect, though some improvement may appear earlier. Setting this expectation supports adherence during the early weeks when side effects may precede benefit.
8A 55-year-old man has frequent heartburn for several weeks without alarm features, partially relieved by antacids. Which step is most appropriate before referral?
A.Begin a once-daily proton pump inhibitor trial with lifestyle advice
B.Start long-term high-dose H2 antagonist and PPI together
C.Recommend daily NSAIDs to reduce inflammation
D.Advise increasing late-night meals
Explanation: For typical GERD symptoms without alarm features, a trial of a once-daily proton pump inhibitor combined with lifestyle measures is appropriate. Persistent or alarm symptoms (dysphagia, bleeding, weight loss) warrant referral.
9A patient on warfarin presents with an INR of 5.5 and no bleeding. The therapeutic range is 2.0 to 3.0. Which action is most appropriate?
A.Give intravenous vitamin K and 4-factor PCC immediately
B.Hold one or more warfarin doses and recheck INR, with low-dose oral vitamin K if indicated
C.Double the next warfarin dose
D.Switch immediately to a higher warfarin dose
Explanation: For an INR of 4.5 to 10 without bleeding, guidelines recommend holding warfarin and monitoring, sometimes with a small dose of oral vitamin K; routine high-dose vitamin K is not needed. INR is rechecked and warfarin resumed at an adjusted lower dose once in range.
10A pregnant patient in her first trimester asks about a safe option for occasional headache. Which analgesic is generally considered the preferred choice?
A.Ibuprofen
B.Acetaminophen
C.Acetylsalicylic acid (ASA)
D.Naproxen
Explanation: Acetaminophen at recommended doses is generally the preferred analgesic in pregnancy. NSAIDs are usually avoided, particularly in the third trimester, due to risks such as premature ductus arteriosus closure and oligohydramnios.

About the PEBC Part I (MCQ) Practice Questions

Verified exam format metadata for PEBC Pharmacist Qualifying Examination Part I (Multiple-Choice Question exam) is pending. The practice questions above remain available while official exam length, timing, passing score, fee, and administrator details are reviewed.