100+ Free ASCP SH Practice Questions
Pass your Specialist in Hematology (SH) exam on the first try — instant access, no signup required.
During primary hemostasis, platelets adhere to exposed subendothelial collagen at the site of vascular injury. This adhesion is mediated by:
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Key Facts: ASCP SH Exam
100
Exam Questions
ASCP BOC SH exam page
2h 30m
Exam Time
ASCP BOC SH exam page
400
Minimum Passing Score
ASCP 100-999 scoring scale
$310
Application Fee
ASCP BOC SH exam page
70%
First-Time Pass Rate
ASCP BOC published data
ASCP BOC lists the SH exam as 100 questions in 2 hours 30 minutes with scores reported on a 100-999 scale and 400 as the minimum passing score. The current SH application fee is $310. ASCP's SH content guideline covers coagulation physiology, laboratory testing, thrombotic and bleeding disorders, anticoagulant monitoring, and quality management.
Sample ASCP SH Practice Questions
Try these sample questions to test your ASCP SH exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.
1Which of the following growth factors is the primary regulator of erythropoiesis?
2During normal hematopoiesis, the pluripotent hematopoietic stem cell first differentiates into which two major progenitor lineages?
3The primary site of hematopoiesis in a healthy adult is the:
4A patient has the following CBC results: RBC 5.8 x 10^6/uL, Hgb 10.2 g/dL, Hct 31%, MCV 53 fL, MCH 17.6 pg, MCHC 32.9 g/dL, RDW 13.5%. The peripheral smear shows microcytic, hypochromic red blood cells with target cells. These findings are most consistent with:
5A patient presents with fatigue and pallor. Laboratory results show: Hgb 8.5 g/dL, MCV 110 fL, reticulocyte count 0.5%, and hypersegmented neutrophils on peripheral smear. Which vitamin deficiency is most likely responsible?
6Which hemoglobin electrophoresis pattern is characteristic of sickle cell trait (HbAS)?
7Schistocytes on a peripheral blood smear are most characteristic of which condition?
8A patient has a positive direct antiglobulin test (DAT), spherocytes on peripheral smear, elevated LDH, decreased haptoglobin, and elevated indirect bilirubin. These findings are most consistent with:
9The reticulocyte count is used to assess bone marrow:
10In flow cytometric immunophenotyping, which CD marker is used as the primary gating marker to identify blast cells in acute leukemia?
About the ASCP SH Exam
The ASCP SH exam certifies specialists in hematology covering primary and secondary hemostasis, coagulation cascade, fibrinolysis, thrombophilia and hypercoagulable states, anticoagulant therapy monitoring, coagulation testing, platelet function testing, factor assays, mixing studies, quality assurance, and point-of-care testing. ASCP exams are delivered at Pearson VUE test centers.
Questions
100 scored questions
Time Limit
2 hours 30 minutes
Passing Score
Scaled score 400 (100-999)
Exam Fee
$310 (ASCP BOC / Pearson VUE)
ASCP SH Exam Content Outline
Coagulation Physiology
Primary hemostasis, secondary hemostasis, coagulation cascade (intrinsic, extrinsic, common pathways), and fibrinolysis
Coagulation Testing
PT, aPTT, fibrinogen, D-dimer, thrombin time, mixing studies, factor assays, inhibitor testing, and algorithmic testing
Bleeding Disorders
Hemophilia A and B, von Willebrand disease, platelet function disorders, DIC, and inherited bleeding disorders
Thrombotic Disorders
Thrombophilia, hypercoagulable states, lupus anticoagulant, antiphospholipid syndrome, and anticoagulant therapy monitoring
Platelet Function Testing
Platelet aggregation, PFA-100/200, flow cytometry, and platelet morphology evaluation
Quality Management
QC procedures, proficiency testing, pre-analytical variables, and point-of-care coagulation testing
How to Pass the ASCP SH Exam
What You Need to Know
- Passing score: Scaled score 400 (100-999)
- Exam length: 100 questions
- Time limit: 2 hours 30 minutes
- Exam fee: $310
Keys to Passing
- Complete 500+ practice questions
- Score 80%+ consistently before scheduling
- Focus on highest-weighted sections
- Use our AI tutor for tough concepts
ASCP SH Study Tips from Top Performers
Frequently Asked Questions
How many questions are on the ASCP SH exam?
ASCP BOC lists the SH exam at 100 questions with a 2 hour 30 minute testing time. Questions are multiple choice and mapped to the SH content guideline domains.
What score do I need to pass ASCP SH?
ASCP reports exam scores on a 100-999 scale. The minimum passing score is 400.
What topics are tested on ASCP SH?
The SH guideline domains cover coagulation testing (25-30%), coagulation physiology (20-25%), bleeding disorders (15-20%), thrombotic disorders (15-20%), platelet function testing (10-15%), and quality management (5-10%).
How much is the ASCP SH exam fee?
The current ASCP BOC SH application fee is $310 (non-refundable) per the ASCP SH credential page.
How should I study for ASCP SH?
Use blueprint-weighted prep: 1) master coagulation testing methods and interpretation, 2) study coagulation cascade physiology, 3) learn bleeding and thrombotic disorder diagnosis, 4) review platelet function testing and quality management.
What are the ASCP SH eligibility requirements?
Candidates typically need a bachelor's degree in medical laboratory science plus documented experience in hemostasis/coagulation. Multiple eligibility routes exist — verify your specific route on the ASCP BOC SH page before applying.