5.1 Medical/Obstetrics/Gynecology Overview

Key Takeaways

  • Medical/OB-GYN is the single largest NREMT Paramedic content area, and the CAT (minimum 110, maximum 150 items, up to 3.5 hours) keeps serving items until your ability estimate stabilizes.
  • Anaphylaxis is treated with epinephrine 0.3 mg IM 1:1,000 in the anterolateral thigh, repeated every 5-15 minutes, plus diphenhydramine and a beta-agonist for bronchospasm.
  • Severe hypoglycemia is corrected with IV dextrose (12.5-25 g of D10 or 25 g of D50) or glucagon 1 mg IM/IN when no IV access exists.
  • Naloxone titrated to restore ventilation (0.4-2 mg IV/IM/IN, repeat q2-3 min) is the antidote for opioid-induced respiratory depression.
  • Recognizing the four core toxidromes (cholinergic, anticholinergic, sympathomimetic, opioid) lets you choose the antidote before a name is known.
Last updated: June 2026

5.1 Medical/Obstetrics/Gynecology Overview

Medical/Obstetrics-Gynecology is the largest cognitive domain on the NREMT Paramedic blueprint, and it carries the heaviest weight precisely because paramedics manage undifferentiated medical complaints far more often than trauma or arrests. On the computerized adaptive test (minimum 110, maximum 150 items, up to 3.5 hours), the engine keeps serving items until your competency estimate is reliably above or below the passing standard. Pediatric content is integrated throughout rather than scored as a fixed percentage, so expect medical scenarios across the age span.

Because the test is adaptive, you cannot "flag and return" — read each medical stem carefully the first time and commit.

What paramedic scope adds

At the paramedic (ALS) level you are expected to establish IV/IO access, draw and interpret a 12-lead ECG, administer the full medical formulary, and make disposition decisions (transport destination, refusal risk, specialty center). The exam tests whether you pick the most appropriate next action for the patient in front of you, not the textbook definition of the disease.

Anaphylaxis

Anaphylaxis is the prototype "act now" medical emergency. The first-line drug is epinephrine 0.3 mg IM of the 1:1,000 (1 mg/mL) concentration injected into the anterolateral thigh (vastus lateralis), repeated every 5-15 minutes for persistent symptoms (pediatric dose 0.01 mg/kg up to 0.3 mg). Adjuncts after epinephrine include diphenhydramine 25-50 mg IV/IM (H1 blocker), an H2 blocker, nebulized albuterol for bronchospasm, and IV fluid boluses for distributive shock.

A common exam trap is choosing diphenhydramine or steroids first — they treat urticaria and the late phase but never replace epinephrine for airway/circulatory compromise.

Glucose emergencies

For a hypoglycemic patient (blood glucose roughly < 60-70 mg/dL with symptoms) who cannot protect the airway, give IV dextrose: 25 g of D50 (50 mL) or, increasingly preferred to reduce vein damage and overshoot, 12.5-25 g of D10 (125-250 mL). When no IV/IO access is available, give glucagon 1 mg IM/IN, which works by mobilizing hepatic glycogen and therefore fails in malnourished or alcoholic patients with depleted stores. Conscious patients with an intact gag reflex can take oral glucose. Recheck glucose after treatment and feed a complex carbohydrate.

The Four Core Toxidromes

A toxidrome is a cluster of signs that points to a class of poison so you can treat before identifying the exact agent. Memorizing these four patterns answers a large share of medical-domain items.

ToxidromeClassic findingsCommon agentsAntidote/treatment
CholinergicSLUDGE/DUMBELS, bradycardia, miosis, bronchorrheaOrganophosphates, nerve agents, carbamatesAtropine (large doses, titrate to dry secretions) + pralidoxime (2-PAM)
Anticholinergic"Hot, dry, red, blind, mad" — tachycardia, mydriasis, dry skin, hyperthermia, delirium, urinary retentionAntihistamines, TCAs, jimsonweed, atropineSupportive, benzodiazepines; physostigmine (in-hospital)
SympathomimeticTachycardia, hypertension, mydriasis, diaphoresis, agitation, hyperthermiaCocaine, methamphetamine, MDMABenzodiazepines, cooling, fluids
OpioidRespiratory depression, miosis (pinpoint pupils), sedation, hypoventilationHeroin, fentanyl, oxycodoneNaloxone, ventilatory support

The single most useful discriminator between anticholinergic and sympathomimetic toxidromes is the skin: anticholinergic patients are dry; sympathomimetic patients are sweaty.

Opioid overdose

For opioid-induced respiratory depression with pinpoint pupils, give naloxone 0.4-2 mg IV/IM (or 2-4 mg intranasal), repeating every 2-3 minutes to a maximum of about 10 mg, titrated to restore adequate ventilation rather than full alertness. In chronic users, start low (0.04-0.4 mg) to avoid precipitating violent withdrawal. With today's high-potency fentanyl analogues, repeat dosing and assisted ventilation between doses are frequently required.

Sepsis

Suspect sepsis in any patient with infection plus signs of organ hypoperfusion (altered mentation, hypotension, tachypnea). Paramedic care centers on early recognition, IV fluid resuscitation (30 mL/kg crystalloid) for hypoperfusion, high-flow oxygen, and a point-of-care lactate where available — a lactate > 4 mmol/L signals anaerobic metabolism and tissue hypoperfusion and predicts higher mortality. Early sepsis alert/notification speeds in-hospital antibiotics. The exam rewards recognizing the septic pattern within a vague "weak and dizzy" stem.

How medical items appear on the CAT

Because the exam is adaptive, a strong run of correct answers will hand you harder, more nuanced medical stems — for example, distinguishing septic shock (warm, vasodilated, low SVR, give fluids then pressors) from cardiogenic shock (cool, pump failure, fluids may worsen pulmonary edema), or recognizing that a hypoglycemic diabetic on an oral sulfonylurea needs prolonged observation because the agent can re-drop the glucose hours after dextrose.

Read every stem for the single most appropriate next action: airway and ventilation problems outrank circulation, life threats outrank diagnostics, and a reversible cause (oxygen, glucose, naloxone) is always addressed before chasing a fancy diagnosis. When two answers are clinically reasonable, the exam usually wants the one that is both time-appropriate and within paramedic scope — for instance, IM epinephrine for perfusing anaphylaxis rather than the IV push reserved for arrest.

Building the medical error log

For each missed medical question, write one sentence beginning "I missed this because" (misread the toxidrome, wrong dose, wrong route, wrong sequence) and a second beginning "Next time I will look for" (the dry-vs-diaphoretic skin clue, the pinpoint pupils, the lactate value). Converting misses into recognizable cues is what turns familiarity into the reliable recall the CAT demands.

Test Your Knowledge

A 22-year-old develops facial swelling, stridor, diffuse urticaria, and hypotension minutes after a bee sting. What is the most appropriate FIRST medication and route?

A
B
C
D
Test Your Knowledge

A patient found unresponsive has a respiratory rate of 4, pinpoint pupils, and no IV access. Which combination best describes the toxidrome and the correct intervention?

A
B
C
D