5.4 Comprehensive Practice Questions

Key Takeaways

  • These mixed items span all three NEX sections — Verbal (58), Mathematics (45), Science (60) — for a final readiness check
  • Work the set under timed conditions to rehearse the 60-minute-per-section pace before exam day
  • Read the explanation for EVERY item, including ones you got right, to confirm your reasoning was correct
  • Wrong answers are your highest-value material; log each by topic, the rule you broke, and the missed clue
  • If you miss several items in one domain, return to that chapter before continuing
  • Aim to finish this set in about 30 minutes to mimic the exam's brisk per-item pace
  • After finishing, list your three weakest topics and review those sections
  • Treat a score above ~70% as a sign you are well-prepared, but keep drilling the misses
Last updated: June 2026

How to Use This Practice Set

This set mixes items from all three NEX sections — Verbal Ability, Mathematics, and Science — so you can rehearse the real exam's blend and pace. Treat it as an active-recall checkpoint, not a reading assignment: answer the entire set before reading any explanation, then mark each miss by skill area, rule, or term.

Instructions

  • Set a timer and aim to finish in about 30 minutes to mirror the NEX's roughly 1-minute-per-item pace
  • Answer each item from memory before checking the explanation
  • Tally right vs wrong and note the topic each wrong answer belongs to
  • Use your results to choose the chapters that get one last review

For every miss, write the reason the correct option wins and why the most tempting distractor fails. That habit matters because the real exam tests the same concept with different wording — if you only memorize the right letter, the reworded version will still trap you. If you miss several items from one domain (say, blood flow through the heart, or percentage change), stop and reread that chapter before moving on.


A Three-Column Review Log

After finishing, build a log with three columns and fill one row per miss:

TopicRule I brokeClue I should have caught
Heart blood flowAtria empty into ventricles on each side"Right atrium" had to come first for deoxygenated return
Percent changeDivide the change by the ORIGINAL value18 ÷ 180, not 18 ÷ 162
Suffix -ectomy-ectomy = surgical removal"appendectomy" = remove the appendix

A Strong Final-Review Loop

  1. Timed attempt of the full set
  2. Explanation review of every item, right and wrong
  3. Targeted reread of the chapters behind your misses
  4. Second attempt after a short break — but mix in a few new items so you are recalling concepts, not memorizing answer order

For calculation or scenario items, say the first step aloud before choosing an option ("first I find the daily dose, then multiply by days"). Verbalizing the plan stops you from snatching a familiar-looking but wrong answer. A score above roughly 70% across this mixed set is a reassuring readiness signal — but the misses, not the score, are what you study in your final days.


Verbal Ability Practice

The items below test vocabulary-in-context and medical-term roots, exactly the Word Knowledge skills the 58-item Verbal section rewards. Use prefix/suffix logic to reason toward each answer rather than relying on a memorized definition. A short, high-yield reference table:

ElementMeaningExample
contra-againstcontraindicated = recommended against
bi-two / bothbilateral = both sides
a- / an-withoutasymptomatic = without symptoms
hyper-excessivehypertension = high blood pressure
-emiablood conditionanemia = deficiency of red cells
-itisinflammationappendicitis = inflamed appendix

When a vocabulary item stumps you, build the meaning from its parts before reading the choices, then match. This converts a memory test into a reasoning test, which is far more reliable under time pressure.

Test Your Knowledge

The word "contraindicated" most nearly means:

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D
Test Your Knowledge

Which word is an ANTONYM of "acute"?

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Test Your Knowledge

"The patient presented with bilateral edema in the lower extremities." The word "bilateral" means:

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D

Mathematics Practice

These items rehearse the Numbers & Operations, Measurement & Conversions, and word-problem skills that dominate the 45-item Math section. Remember there is no geometry on the NEX, so do not waste review time on area/volume formulas. Estimate first, then verify with your optional 4-function calculator. Keep these conversions memorized — they recur constantly:

ConversionFactor
Pounds to kilograms÷ 2.2
Celsius to Fahrenheit(C × 9/5) + 32
Cups to milliliters× 240
Percent of a number(part ÷ whole) × 100
Percent change(original − new) ÷ original × 100

The single most common careless error in this section is dividing by the wrong base in a percent-change problem (using the new value instead of the original) — circle the word "original" or "started" in the stem before you compute.

Test Your Knowledge

A patient takes 2.5 mL of medication 3 times daily for 10 days. How many total mL are needed?

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Test Your Knowledge

A patient's temperature is 39.5°C. What is this in Fahrenheit?

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Test Your Knowledge

If a patient's weight drops from 180 lb to 162 lb, what is the percentage of weight loss?

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Test Your Knowledge

A solution contains 15 mL of medication in 500 mL of saline. What is the concentration as a percentage?

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Science Practice

These items span biology, anatomy & physiology, genetics, and nutrition — the content that fills the 60-item Science section (the largest on the NEX, and physics has been removed, so skip mechanics in review). Eliminate options from the wrong body system, and let absolute words ("always," "never," "all," "none") flag likely-wrong choices. A quick orientation to the eight systems most tested:

SystemCore jobHigh-yield fact
CardiovascularTransport bloodRight side handles deoxygenated return
RespiratoryGas exchangeOccurs across alveoli into capillaries
UrinaryFilter blood, make urineKidneys filter ~180 L/day
NervousElectrical signalingNeurons transmit impulses
EndocrineHormonal regulationInsulin lowers blood glucose
DigestiveBreak down foodAbsorption mainly in small intestine

When two answers both look plausible, the one stated in moderate, precise language usually wins over the extreme-sounding option.

Test Your Knowledge

Which organ system filters blood and removes waste products as urine?

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Test Your Knowledge

Diffusion is the movement of molecules from:

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Test Your Knowledge

Which type of blood vessel has walls only ONE cell thick, allowing gas and nutrient exchange?

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Test Your Knowledge

A Punnett-square cross of Bb × bb produces what phenotype ratio?

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Test Your Knowledge

Which vitamin deficiency causes scurvy?

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Test Your Knowledge

Which sequence correctly describes blood flow through the heart?

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D
Test Your Knowledge

The suffix "-ectomy" in "appendectomy" indicates:

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D
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