19.2 Dermatology
Key Takeaways
- Primary lesion vocabulary is exam-critical: macule/patch (flat), papule/plaque/nodule (solid raised), vesicle/bulla (fluid-filled), and the 1 cm size threshold separates small from large forms
- The ABCDE mnemonic for melanoma — Asymmetry, Border irregularity, Color variation, Diameter >6 mm, Evolution — and the ugly duckling sign guide urgent dermatology referral
- Basal cell carcinoma is the most common skin cancer (pearly papule with telangiectasia); squamous cell carcinoma arises on sun-damaged skin and may metastasize
- Psoriasis shows well-demarcated erythematous plaques with silvery scale, Auspitz sign, and Koebner phenomenon; atopic dermatitis favors flexural creases in children
- Bullous pemphigoid produces tense bullae in elders (autoimmune, subepidermal); pemphigus vulgaris produces flaccid bullae with mucosal erosions (autoimmune, intraepidermal)
Dermatology accounts for roughly 11% of Associated Clinical Sciences on NBCE Part II. Chiropractors routinely inspect skin on the back, shoulders, and scalp that patients never see themselves, so the boards test two skills: naming what you see with correct morphology vocabulary, and recognizing which lesions are benign, infectious, or malignant enough to demand urgent referral.
Lesion Morphology: The Foundation
Precise terminology is the language of dermatology. The 1 cm threshold and whether a lesion is flat, solid, or fluid-filled do most of the classifying.
Primary Lesions
| Lesion | Definition | Classic Example |
|---|---|---|
| Macule | Flat, nonpalpable color change, under 1 cm | Freckle, petechia |
| Patch | Flat color change, 1 cm or larger | Vitiligo patch |
| Papule | Solid raised lesion, under 1 cm | Wart, nevus |
| Plaque | Raised, flat-topped, 1 cm or larger | Psoriasis |
| Nodule | Solid lesion extending into dermis/subcutis | Rheumatoid nodule |
| Vesicle | Fluid-filled, under 1 cm | Herpes simplex |
| Bulla | Fluid-filled, 1 cm or larger | Bullous pemphigoid |
| Pustule | Pus-filled | Folliculitis, acne |
| Wheal | Transient edematous plaque | Urticaria |
Secondary Lesions
Scale (flaking), crust (dried serum/blood/pus), erosion (shallow loss of epidermis), ulcer (deeper tissue loss), lichenification (thickened skin from chronic rubbing), fissure (linear crack), and scar (fibrotic replacement) describe how primary lesions evolve.
Infections
Bacterial
- Impetigo — honey-colored crusts, highly contagious; Staphylococcus aureus or Streptococcus pyogenes
- Cellulitis — spreading erythema, warmth, tenderness; requires antibiotics; distinguish from deep vein thrombosis and contact dermatitis
- Folliculitis — pustules centered on hair follicles
- Erysipelas — well-demarcated raised border, often on face; group A strep
Viral
- Herpes simplex — grouped vesicles on erythematous base; HSV-1 (oral) and HSV-2 (genital)
- Herpes zoster (shingles) — painful vesicular eruption in a dermatomal distribution; do not adjust through active vesicles; postherpetic neuralgia is a complication
- Verruca vulgaris (warts) — hyperkeratotic papules; HPV
- Molluscum contagiosum — umbilicated pearly papules
Fungal
- Tinea corporis (ringworm) — annular plaque with central clearing and active scaly border; KOH prep shows hyphae
- Tinea pedis — interdigital maceration, scaling; athlete's foot
- Tinea capitis — scaly patches with broken hairs; requires systemic antifungals
- Candidiasis — beefy red plaques with satellite pustules in intertriginous areas
Tumors: Benign and Malignant
Benign
- Seborrheic keratosis — waxy, stuck-on appearance; "barnacle" of aging
- Cherry angioma — bright red papule; common with age
- Lipoma — soft, mobile subcutaneous nodule
- Dermatofibroma — firm dimple sign on lateral compression
Premalignant and Malignant
- Actinic keratosis — rough, scaly patch on sun-exposed skin; precursor to SCC
- Basal cell carcinoma (BCC) — most common skin cancer; pearly papule with rolled border and telangiectasia; rarely metastasizes
- Squamous cell carcinoma (SCC) — keratotic nodule or ulcer on sun-damaged skin; can metastasize
- Melanoma — most dangerous; use ABCDE: Asymmetry, Border irregularity, Color variation, Diameter >6 mm, Evolution. The ugly duckling sign — one nevus unlike the others — is a referral trigger
Any suspicious pigmented lesion, nonhealing ulcer, or rapidly growing nodule warrants dermatology referral — not observation in a chiropractic office.
Dermatitis
| Type | Key Features | Trigger/Population |
|---|---|---|
| Atopic dermatitis | Pruritic, flexural (antecubital, popliteal) in children; lichenified plaques in adults | Atopic triad: eczema, asthma, allergic rhinitis |
| Contact dermatitis (allergic) | Pruritic vesicles at site of exposure; linear pattern suggests plant contact | Type IV hypersensitivity; poison ivy, nickel |
| Contact dermatitis (irritant) | Burning, dryness, fissuring; no prior sensitization needed | Soaps, solvents, frequent hand washing |
| Seborrheic dermatitis | Greasy yellow scale on scalp, eyebrows, nasolabial folds | Malassezia yeast; dandruff in mild form |
| Stasis dermatitis | Erythema, scaling, hyperpigmentation on lower legs | Chronic venous insufficiency |
Scaling Diseases
- Psoriasis — well-demarcated erythematous plaques with silvery micaceous scale on extensor surfaces, scalp, and sacrum. Auspitz sign (pinpoint bleeding when scale removed) and Koebner phenomenon (lesions at sites of trauma) are classic. Associated with psoriatic arthritis
- Pityriasis rosea — herald patch followed by Christmas-tree distribution on trunk; self-limited
- Lichen planus — pruritic polygonal purple papules (the 6 P's); Wickham striae on oral mucosa
Vesicular and Bullous Disorders
- Dyshidrotic eczema — pruritic vesicles on palms and soles
- Dermatitis herpetiformis — intensely pruritic vesicles on extensor surfaces; associated with celiac disease
- Bullous pemphigoid — tense bullae in elderly; autoimmune, subepidermal split; Nikolsky sign negative
- Pemphigus vulgaris — flaccid bullae with painful mucosal erosions; intraepidermal split; Nikolsky sign positive
Pigmentary Disorders
- Vitiligo — depigmented patches; autoimmune destruction of melanocytes
- Melasma — symmetric hyperpigmented patches on face; associated with hormones and sun
- Post-inflammatory hyperpigmentation — darkening after inflammation or injury
- Albinism — congenital absence of melanin; increased skin cancer and vision risk
Hair and Sebaceous Disorders
- Acne vulgaris — comedones, papules, pustules, nodules; driven by androgens, sebum, Cutibacterium acnes, and follicular plugging
- Rosacea — centrofacial erythema, telangiectasia, papulopustules; triggers include heat, alcohol, and spicy food
- Alopecia areata — smooth round patches of hair loss; autoimmune
- Androgenetic alopecia — patterned thinning; male and female patterns differ
- Telogen effluvium — diffuse shedding after physiologic stress (surgery, illness, childbirth)
Chiropractic Relevance
During examination you may be the first clinician to notice a changing mole on the upper back, shingles in a thoracic dermatome before the vesicles appear, or cellulitis masquerading as local musculoskeletal pain. Document findings, avoid manipulating through infected or vesicular skin, and refer promptly when malignancy or systemic infection is suspected.
A patient has a 7 mm pigmented lesion on the upper back with irregular borders, multiple colors, and recent enlargement. Which feature is part of the ABCDE melanoma screening mnemonic?
A 45-year-old man has well-demarcated erythematous plaques with silvery scale on his elbows and knees. Pinpoint bleeding appears when the scale is scraped away. These findings are most consistent with:
An elderly woman develops large tense blisters on her trunk and limbs without mucosal involvement. Nikolsky sign is negative. The most likely diagnosis is:
A pearly papule on the nasal ala with rolled borders and visible telangiectasia is most characteristic of which malignancy?