3.5 Recognizing Indicators of Substance Use and Co-Occurring Disorders for Referral

Key Takeaways

  • Identifying indicators of substance use and co-occurring disorders for referral is a required NCPRSS education area; the peer notices, asks, and connects but never diagnoses.

  • The DSM-5-TR defines a substance use disorder by at least 2 of 11 criteria within 12 months: mild is 2 to 3, moderate 4 to 5, and severe 6 or more.

  • Tolerance and withdrawal do not count toward a substance use disorder diagnosis when they occur only with medication taken as prescribed.

  • Signs of mania, psychosis, suicidal thinking, severe withdrawal, or pregnancy with opioid use call for urgent or emergency referral.

  • Effective referrals involve permission, choice, consent before sharing information, a warm handoff, and follow-up within a day or two.

Last updated: October 2026

3.5 Recognizing Indicators of Substance Use and Co-Occurring Disorders for Referral

Note

Quick Answer: NCC AP's required NCPRSS education includes "identification of indicators of substance use and/or co-occurring disorders for referral." The peer's job is to notice, ask, and connect, never to diagnose. Knowing how clinicians define substance use disorders (the DSM-5-TR's 11 criteria in four groups) and the common signs of mental health conditions helps a peer recognize when someone needs a professional evaluation, how urgent it is, and how to make a warm referral with the person's consent.


Why Peers Need to Recognize Indicators

People with substance use problems frequently also live with depression, anxiety, trauma-related conditions, bipolar disorder, or psychotic disorders. When both are present, they are co-occurring disorders, and outcomes are better when both are addressed together (integrated care). A peer may be the first person someone trusts enough to describe symptoms they have never told a clinician. Recognizing those indicators, and knowing what to do next, is part of the role.

Important

Recognizing is not diagnosing. A peer can say, "What you're describing sounds really hard, and a doctor or counselor could help figure out what's going on. Would you like help setting that up?" A peer does not say, "You have bipolar disorder."


How Clinicians Define Substance Use Disorder (for Recognition, Not Diagnosis)

The DSM-5-TR defines a substance use disorder as a problematic pattern of use causing clinically significant impairment or distress, shown by at least 2 of 11 criteria within 12 months. The criteria fall into four groups:

GroupCriteria (paraphrased)
Impaired controlUsing more or longer than intended; wanting or failing to cut down; spending a lot of time getting, using, or recovering; craving
Social impairmentFailing major obligations at work, school, or home; continuing despite social or relationship problems; giving up important activities
Risky useUse in physically hazardous situations; continuing despite knowing it causes or worsens a physical or psychological problem
PharmacologicalTolerance; withdrawal

Severity is mild (2 to 3 criteria), moderate (4 to 5), or severe (6 or more). Tolerance and withdrawal do not count toward the diagnosis when they occur only with medications taken as prescribed under medical supervision, such as buprenorphine or a prescribed opioid for pain.

Indicators a Peer Might Notice

AreaPossible indicators
Statements"I always end up drinking more than I planned," "I've tried to quit three times," "I need more to feel anything now"
BehaviorMissed appointments, borrowing money, secrecy, new friends tied to use, loss of interest in old activities
PhysicalSigns of intoxication or withdrawal (see Chapter 10), injection marks or abscesses, weight loss, frequent illness
ConsequencesJob loss, legal problems, housing instability, relationship breakdown linked to use

Indicators of Mental Health Conditions

Possible conditionIndicators to noticeTypical referral urgency
DepressionPersistent low mood, loss of interest, sleep or appetite changes, hopelessness, slowed thinkingRoutine to urgent; emergency if suicidal thoughts with a plan
Anxiety and panicConstant worry, panic attacks, avoidance that limits daily lifeRoutine
Trauma-related conditionsNightmares, flashbacks, hypervigilance, avoiding remindersRoutine to urgent
Bipolar disorder (mania)Days of little sleep without tiredness, racing thoughts, grandiosity, risky spending or sexUrgent
PsychosisHearing or seeing things others do not, fixed false beliefs, disorganized speechUrgent; emergency if danger to self or others
Cognitive changesNew confusion, memory loss, disorientationUrgent medical evaluation (can signal intoxication, withdrawal, infection, or brain injury)

Many of these symptoms can be caused or worsened by substances, by withdrawal, or by medical problems. Sorting out whether symptoms are substance-induced or independent is a clinical task; the peer's task is to notice and connect.


The Four-Quadrant Model of Co-Occurring Disorders

Planners use the four-quadrant model (developed by national mental health and substance use program directors' associations) to match people with services by the severity of each condition:

Lower substance use severityHigher substance use severity
Higher mental health severityQuadrant II: usually served in mental health settingsQuadrant IV: needs intensive integrated care
Lower mental health severityQuadrant I: often served in primary careQuadrant III: usually served in addiction treatment settings

The model reminds peers that "where to refer" depends on both conditions, and that people in Quadrant IV are the most likely to fall between systems without active coordination.


Matching Urgency to the Situation

LevelExamplesPeer action
Emergency (now)Suicide plan or attempt, overdose, severe withdrawal, violent psychosis, medical emergency911 or 988 and the agency crisis protocol; stay with the person
Urgent (same day to 24 hours)Pregnancy with opioid use, mania, new psychosis without immediate danger, worsening depressionSame-day clinician contact or walk-in services
RoutineOngoing anxiety, untreated depression without safety concerns, wanting an SUD assessmentScheduled referral with follow-up

Making the Referral Count

  1. Ask permission and explain why. "Would you be open to talking with someone who can look at this more closely?"
  2. Offer choices of providers, times, and formats, including telehealth.
  3. Get consent before sharing information with an outside provider (42 CFR Part 2; Code II-22).
  4. Use a warm handoff (Section 3.3): call together, introduce the person, or go with them.
  5. Follow up within a day or two to see whether the connection happened and what is next.

Tip

On exam scenarios, look for the answer that recognizes, asks, and connects with consent. Eliminate answers that diagnose, ignore clear warning signs, or share information without permission outside an emergency.

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Recognize, Triage, and Refer
Test Your Knowledge

Over two weeks, a participant tells a peer specialist that they have barely slept but feel full of energy, have started three businesses, and spent their rent money on equipment. They deny any thoughts of harming themselves. What is the most appropriate peer response?

A

Tell the participant that these symptoms show bipolar I disorder and that they need to start a mood stabilizer as soon as possible.

B

Treat the change as positive motivation in recovery and help the participant write a business plan for the new ventures.

C

Share concern about the changes and help them see a clinician the same day.

D

Wait to see whether the energy fades on its own before mentioning anything, so the participant does not feel judged or labeled.

Test Your Knowledge

A participant who takes buprenorphine as prescribed says they get withdrawal symptoms if they miss a dose and needed a higher dose at first. They worry this means they "still have an active addiction." Which statement is accurate?

A

Tolerance and withdrawal from a medication taken as prescribed do not count toward an SUD diagnosis.

B

Any withdrawal symptoms prove that the person still meets criteria for a severe opioid use disorder and should stop the medication.

C

Withdrawal counts toward the diagnosis, but tolerance does not, so the participant meets at least one active criterion of opioid use disorder.

D

Only a urine drug screen, not symptoms, can tell whether a person on buprenorphine still has an opioid use disorder.

Test Your Knowledge

A participant who is about 10 weeks pregnant tells a peer specialist she is using fentanyl daily and is afraid to tell her doctor. How should the peer respond?

A

Advise her to stop fentanyl immediately on her own, because any opioid exposure during pregnancy is more dangerous than withdrawal.

B

Promise to keep the information secret and avoid mentioning treatment until she feels ready to bring it up again on her own.

C

Report her to child protective services right away, since substance use during pregnancy is always a mandatory report everywhere.

D

Acknowledge her fear, explain that treatment with medication is recommended in pregnancy, and offer a same-day warm referral.

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