22.2 Selecting Cases for Second-Level Review
Key Takeaways
Second-level referral criteria, reviewer qualifications and timing are locally defined. Evaluate support concerns in the full record rather than apply one universal diagnostic or mandatory-referral cutoff.
Changing the only MCC does not necessarily remove every severity tier. Assess remaining qualifying diagnoses and re-run the actual grouper.
Identify the quality measure, program and version. PSI 04 is outside AHRQ PSI 90 v2025, and POA rules do not create a universal exclusion for every indicator.
Review mortality and complex procedures for accurate facts and applicable model inputs; do not seek a preferred ROM subclass, payment result or quality exclusion.
Different review authorities have different scopes. The April 2025 RAC Regions 3–5 SOW prohibits clinical validation in those RAC reviews while permitting specified other reviews.
Selecting Cases for Second-Level Review
A second-level review brings additional expertise to a documentation, coding or clinical-support question that needs closer examination. It can occur during the stay, before billing or retrospectively. The organization should define its referral criteria, reviewer qualifications, priorities and escalation process. There is no national requirement that every death, rejected query or single-MCC record receive the same review before discharge.
The purpose is accurate representation of the encounter. A review may support the existing documentation, identify a needed clarification, reveal an inappropriate query or identify a reporting error. It should remain open to each outcome. AHIMA's clinical-validation brief describes a second-level process as a possible organizational approach, particularly when ambiguity or recurring denial risks need deeper review. AHIMA Clinical Validation, 2023 Update
Define a referral by the question it must resolve
| Possible local trigger | Useful referral question | Boundary |
|---|---|---|
| A diagnosis is the only qualifying CC or MCC | Is the diagnosis supported and reportable, and is the grouping correct? | Do not look for substitute diagnoses merely to preserve payment |
| A quality-indicator flag appears | Were the correct data and applicable measure rules used? | A flag is not a finding of preventable harm or an instruction to secure an exclusion |
| An inpatient dies or a case has an unexpected risk classification | Does the record accurately describe the clinical course and applicable model inputs? | Do not seek a predetermined mortality-risk subclass |
| A complex procedure or duration affects reporting | Do the operative report, procedure details and timeline support the assigned code? | A payment estimate does not establish the procedure or duration |
| A documented diagnosis has unclear or contradictory support | Is clarification needed after review of the full clinical picture? | A screening threshold is not an automatic diagnosis or deletion rule |
| A query or provider response raises a concern | Is the query appropriate, and what question remains unresolved? | A refusal or “unable to determine” response is not itself evidence of misconduct |
Targeted referral and sampling serve different purposes. A high-risk workqueue can prioritize known concerns; an appropriately designed sample can reveal issues that the trigger logic misses. Choosing one does not eliminate the value of the other. Set priorities using the question, consequence, timeliness and available expertise, with a route for manual referrals when software does not recognize the issue.
Review a single-CC or single-MCC case without assuming the result
“Fragile DRG” is an informal operational term for a case whose grouping depends on one qualifying secondary diagnosis. The actual effect of changing that diagnosis depends on the DRG family, remaining diagnoses, exclusions, procedures and other grouper inputs.
In the FY2027 v44 heart-failure-and-shock family, MS-DRG 291 is with MCC, 292 is with CC and 293 is without CC/MCC. Consider an illustrative case already appropriately assigned to this family: its sole qualifying MCC is removed after proper clarification, but another qualifying CC remains. With other grouping factors unchanged, the CC tier remains relevant; the case does not automatically fall to 293. Re-run the applicable grouper using the final supported information. CMS FY2027 v44 definitions, Appendices A and C
The review should ask why the diagnosis is documented, what supports it, whether any conflict needs clarification and whether reporting rules are met. It should not attempt to create “comorbidity redundancy.” Each additional diagnosis must independently satisfy the applicable requirements. National approximate dollar amounts or relative weights cannot establish the actual payment loss for an individual hospital claim. FY2027 ICD-10-CM guidelines, Sections I.A.19 and III
Treat a quality flag as a request to verify the measure
For each flag, establish the measure, reporting program, version, population and data period. Then review numerator and denominator logic, exclusions, codes, POA indicators and procedure dates as applicable. Keep the clinical assessment, coding decision and measure calculation distinct.
For example, PSI 04 is not a component of AHRQ PSI 90 v2025. A referral can still concern PSI 04, but it should not call that review a PSI 90 component review. PSI 11 likewise has several diagnosis/procedure pathways and timing rules; it is not simply “postoperative ventilation of at least 96 hours.” Review the actual specification rather than a shortened workqueue label. AHRQ PSI 90 v2025 composite guide; PSI 11 v2025 specification, pages 1–3
POA is determined relative to the inpatient admission order, with the applicable rules for conditions developing during outpatient services before that order. It is not determined simply by arrival at the hospital or the date a copied sentence was entered. U means insufficient documentation; it does not prove a condition was acquired in the hospital. A Y indicator is not a universal statutory exclusion from every PSI. Apply the particular measure's rules and clarify unresolved documentation neutrally. FY2027 POA guidelines
CMS's HAC Reduction Program uses CMS PSI 90 alongside specified infection measures. Its 1% payment reduction concerns applicable hospitals whose Total HAC Score falls in the worst-performing quartile; a single flagged case does not automatically impose that reduction. Do not transfer a measure or penalty rule to the separate Hospital VBP Program without checking that program and year. CMS HAC Reduction Program
Review mortality and complex procedures for accuracy
An expired patient's record may warrant closer review of the course, diagnosis evolution, admission timing and completeness. The outcome does not authorize a search for diagnoses designed to raise expected mortality. Solventum APR-DRG SOI/ROM subclasses are a particular methodology; they are not interchangeable with all CMS mortality measures, rating systems or registries. CMS publicly reports condition- and procedure-specific 30-day risk-standardized mortality measures. Determine the actual model before asserting that a diagnosis, DNR status or palliative-care code changes its result. A low-risk classification followed by death is a review signal, not proof of poor care. Solventum APR-DRGs; CMS outcome measures
For a procedure referral, identify the exact uncertainty: objective, body part, approach, device, qualifier or duration. Read the operative and relevant respiratory records and apply the current PCS definitions and guidelines. The ventilation category for greater than 96 consecutive hours differs from 24–96 hours; exactly 96 is not greater than 96. A workqueue flag does not establish ventilation hours or an MS-DRG, and an ECMO label alone does not establish every grouping input. FY2027 PCS tables
Refer clinical-support concerns without converting them into automatic denials
Malnutrition, sepsis, respiratory failure, kidney injury and encephalopathy can raise difficult questions, but the concern must be explained in the actual case. Use the relevant clinical lesson and source rather than applying a universal list of mandatory diagnostic cutoffs.
For example, albumin and prealbumin alone do not diagnose malnutrition. Their presence can prompt review of the provider's assessment and the nutrition record; their absence or an incomplete short vignette does not itself rule malnutrition out. Similarly, a treatment response, oxygen flow rate or one laboratory value should not replace the complete clinical picture. The reviewer identifies the concern and supports appropriate clarification; the responsible provider exercises diagnostic judgment. ASPEN visceral-protein position paper; 2026 query guidance
Use the actual review authority when analyzing denials. CMS's April 2025 Regions 3–5 RAC statement of work distinguishes coding validation and medical-necessity review from clinical validation and prohibits clinical validation in those RAC reviews. Do not treat every commercial clinical-validation denial as an example of the same RAC authority. CMS RAC Regions 3–5 statement of work, pages 13 and 24
Finally, evaluate the original query before escalating a provider interaction. A correct response may be that the diagnosis cannot be determined or that the existing record already answers the question. Use the organization's compliant follow-up process for a genuine unresolved issue. A second-level reviewer or physician advisor can help assess the query and communication; the role does not authorize pressure for a preferred diagnosis. 2026 query guidance, provider collaboration and multiple-query sections
A case is appropriately grouped in the v44 heart-failure-and-shock family. After proper clarification, its sole qualifying MCC is removed, but another qualifying CC remains and all other grouping factors are unchanged. What should the reviewer conclude?
The case must automatically fall from MS-DRG 291 to 293 because the only MCC was removed.
The case must remain in MS-DRG 291 because the principal heart-failure diagnosis has not changed.
The CC tier remains relevant; verify the supported inputs and grouper result rather than assume the case falls to the base tier.
The remaining diagnosis should be relabeled as an MCC to preserve the original grouping.
A local workqueue flags a possible postoperative quality event. What is the most appropriate second-level review approach?
Identify the actual measure, program and version, then verify the clinical documentation and relevant numerator, denominator, exclusion, POA and timing data.
Change the POA indicator to Y whenever a preoperative note mentions symptoms that could be related to the event.
Remove the diagnosis from the abstract because any flagged event automatically creates a 1% hospital payment penalty.
Use one exclusion checklist for all PSIs because a Y indicator removes every diagnosis from every PSI calculation.
A provider documents severe malnutrition. A short referral summary reports stable weight, normal BMI and a low prealbumin value but does not include the full nutrition assessment. What is the appropriate review stance?
Confirm severe malnutrition from the prealbumin result because that marker is sufficient by itself.
Rule out malnutrition because a normal BMI excludes the diagnosis under every consensus framework.
Delete the diagnosis because the short summary does not describe every characteristic in one preferred checklist.
Review the complete assessment and relevant clinical context, then seek neutral clarification if the documentation or support remains unclear.
Sections you finish are checked off in the contents.