Blood Loss, Infiltration, Clotting, Air, Hemolysis, and Fever

Key Takeaways

  • Blood loss and access infiltration require immediate attention to patient safety and access protection.
  • Clotting signs include pressure changes, darkening blood, streaking, and impaired circuit flow.
  • Air, hemolysis, fever, chills, or suspected contamination are high-risk events that require urgent escalation.
  • Do not return blood to the patient if safety is uncertain or facility policy prohibits it for the event.
Last updated: May 2026

High-Risk Complications

Blood outside the circuit, air in the bloodline, hemolysis, clotting, and fever or chills are not routine alarms. These findings can become emergencies quickly. The technician's role is to recognize danger, keep the access and circuit secure, follow policy, notify the RN or qualified staff, and document the event.

Access and Circuit Red Flags

EventCluesPriority Action
Blood lossWet clothing, leaking connection, dislodged needle, blood on chairStop blood loss, protect access, call for help.
InfiltrationSwelling, pain, firmness, poor flow near needleStop using affected needle per protocol and notify RN.
ClottingRising pressures, dark blood, streaked dialyzer, clots in chamberAssess circuit, report, do not ignore trend.

Emergency Red Flags

EventCluesPriority Action
Air in lineAir detector alarm, visible air, loose connectionClamp as required by machine safety, call RN, follow protocol.
HemolysisCherry or port-wine blood, pain, shortness of breath, heat or chemical concernStop treatment per policy, do not return blood unless directed, escalate.
Fever/chillsRigors, temperature rise, malaiseNotify RN, assess vitals, follow infection and culture policy.

Hemolysis is especially high risk because damaged red blood cells can release potassium and cause severe patient harm. Possible causes include dialysate problems, temperature issues, chemical contamination, kinked bloodlines, or mechanical damage. Treat suspected hemolysis as an emergency.

For suspected air embolism, the exam-safe response is immediate escalation and facility emergency procedure. Do not bypass alarms or silence them without correcting the cause. Any equipment or setup concern should be reported and documented as an adverse event according to facility policy.

Test Your Knowledge

During dialysis, the technician sees blood soaking the patient's sleeve near the access arm. What is the priority?

A
B
C
D
Test Your Knowledge

Which finding is most concerning for possible hemolysis?

A
B
C
D
Test Your Knowledge

A venous pressure has been rising for 20 minutes, the venous chamber looks darker, and small clots are visible. What should the technician suspect?

A
B
C
D