3.2 Transmission-Based Precautions

Key Takeaways

  • Transmission-Based Precautions are used IN ADDITION to Standard Precautions for residents with specific known or suspected infections.
  • Contact Precautions (gown + gloves) apply to C. diff, MRSA, and other organisms spread by touch.
  • Droplet Precautions (surgical mask within ~6 feet) apply to influenza, pertussis, and mumps.
  • Airborne Precautions require a fit-tested N95 respirator and a negative-pressure (AIIR) room for tuberculosis (TB), measles, and chickenpox.
  • Bloodborne pathogens (HIV, hepatitis B and C) spread mainly through contaminated sharps; never recap needles and report any needlestick immediately.
Last updated: June 2026

The Three Categories of Transmission-Based Precautions

Transmission-Based Precautions are the second tier of infection control. They are used in addition to Standard Precautions when a resident is known or suspected to be infected with a pathogen that needs extra protection. The CDC defines three categories based on how the organism spreads. The exam frequently asks you to match a disease to the correct precaution and PPE.

PrecautionPPE RequiredRoom / SetupExample Diseases
ContactGloves and gownPrivate room preferred; dedicated equipmentC. diff, MRSA, VRE, scabies, draining wounds
DropletSurgical mask within ~6 feetPrivate room; door may stay openInfluenza (flu), pertussis (whooping cough), mumps, rubella
AirborneFit-tested N95 respiratorNegative-pressure (AIIR) room, door closedTuberculosis (TB), measles, chickenpox (varicella)

A simple memory aid is "My Chicken Has TB" for airborne diseases: Measles, Chickenpox, and TB. These three require the strongest protection because the pathogen lingers in the air.

Isolation, Cleaning, and Disinfection

When a resident is on Transmission-Based Precautions, an isolation cart with PPE is placed outside the door, and a sign lists the required precautions. Put PPE on before entering the room and remove it inside the room at the doorway (except the respirator, which comes off after you leave an airborne-isolation room). Always perform hand hygiene as the final step.

Key isolation rules tested on the exam:

  • Dedicate equipment (blood-pressure cuff, thermometer) to that resident whenever possible to avoid carrying pathogens out.
  • Never leave the isolation room wearing contaminated PPE.
  • Provide emotional support — isolation can cause loneliness and depression, which the CNA must address.

Cleaning vs. disinfecting: Cleaning removes visible dirt with soap and water; disinfecting uses a chemical to destroy most pathogens on surfaces. Always clean before you disinfect, and clean from the cleanest area to the dirtiest to avoid spreading germs. A fresh bleach solution or an EPA-registered disinfectant is used for C. diff because it kills spores that ordinary cleaners do not.

Handling Linens, Waste, and Bloodborne Pathogens

Soiled linens are a common exam topic. Roll them away from your body with the dirtiest area folded inward, hold them away from your uniform, and never shake linens — shaking sends pathogens into the air. Never place dirty linens on the floor or on clean surfaces. Place wet or contaminated linens in a leak-proof bag.

Regulated (biohazard) waste — items saturated with blood or body fluids and used sharps — goes into red biohazard bags or puncture-proof sharps containers, never the regular trash.

Bloodborne Pathogens

The OSHA Bloodborne Pathogens Standard protects workers from pathogens carried in blood, especially HIV (human immunodeficiency virus), HBV (hepatitis B), and HCV (hepatitis C). These spread mainly through:

  • Needlesticks and sharps injuries (the leading cause)
  • Contact of infected blood with non-intact skin or mucous membranes

CNA exam rules for bloodborne pathogens:

  • Never recap, bend, or break used needles — drop sharps directly into a sharps container.
  • The employer must offer the hepatitis B vaccine free of charge.
  • Report any exposure (needlestick, splash) immediately so post-exposure care can begin.
  • Treat all blood as infectious — this is the core of Standard Precautions, also called Universal Precautions for blood.

Matching Diseases to Precautions and the Psychological Side of Isolation

The exam loves to give a short scenario and ask for the right precaution, so anchor each common organism firmly:

  • C. difficile (C. diff): Contact Precautions, plus soap-and-water handwashing (not sanitizer) and a bleach disinfectant, because alcohol does not kill its spores.
  • MRSA / VRE: Contact Precautions with gown and gloves; these drug-resistant organisms spread by touch.
  • Influenza, pertussis, mumps: Droplet Precautions with a surgical mask when within about six feet.
  • Tuberculosis, measles, chickenpox: Airborne Precautions with an N95 respirator and a negative-pressure room.

Some conditions need two precautions at once. A resident with disseminated shingles (herpes zoster) or chickenpox, for example, may need both Contact and Airborne Precautions because the pathogen spreads by skin contact and through the air. When unsure, follow the sign on the isolation cart and ask the nurse.

Supporting the Isolated Resident

Isolation protects others but can leave a resident feeling lonely, frightened, or stigmatized. The CNA must guard the resident's dignity and mental health: explain why the precautions are needed, spend time talking, answer call lights promptly, and never act as though the resident is 'untouchable.' Provide diversions, encourage family contact, and report signs of depression. Good infection control protects the body; good emotional care protects the person. Both are part of safe, competent CNA practice and both appear on the exam.

Transporting an Isolation Resident

If a resident on precautions must leave the room for a test, the resident wears the barrier that contains their organism — for example, a surgical mask on a resident with an airborne or droplet illness — while staff use the PPE appropriate to the precaution. Notify the receiving department in advance, and clean any transport equipment afterward. The goal is to contain the pathogen at its source rather than spread it through the hallways.

Test Your Knowledge

A resident has active tuberculosis (TB). Which precaution and PPE does the CNA need?

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Test Your Knowledge

A CNA is caring for a resident on Contact Precautions for MRSA. Which PPE is required?

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B
C
D
Test Your Knowledge

How should a CNA handle a resident's soiled linens?

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D