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9.1 Evidence-Based Care Transition Models and Discharge Execution

Key Takeaways

  • Project RED (Re-Engineered Discharge) standardizes discharge with 12 components, including a personalized After Hospital Care Plan and a reinforcement phone call 2 to 3 days after discharge.

  • The Care Transitions Intervention (CTI or Coleman Model) utilizes a Transition Coach across a 30-day cross-site period to empower patient self-management across four core pillars: medication self-management, dynamic personal health record (PHR), timely physician follow-up, and knowledge of red-flag symptoms.

  • Project BOOST deploys the targeted 8Ps risk assessment tool (Problem medications, Psychological, Principal diagnosis, Polypharmacy, Poor health literacy, Patient support, Prior hospitalizations, Palliative care) to customize interdisciplinary interventions for high-risk older adults.

  • Discharge medication reconciliation requires a rigorous five-step comparative audit, ideally integrated with bedside delivery ('Meds-to-Beds') programs that eliminate retail pharmacy fill gaps, resolve prior authorizations, and secure copay assistance prior to discharge.

  • The discharge teach-back method employs 'chunk-and-check' verification to confirm patient and caregiver comprehension of medication regimens, red-flag symptoms, and emergency contact numbers, replacing passive acknowledgment with active restatement.

Last updated: October 2026

Evidence-Based Care Transition Models and Discharge Execution

The transition from an acute care hospital to home or a post-acute facility represents the most clinically vulnerable juncture in a patient's healthcare trajectory. A widely cited study of discharged medical patients found that about 1 in 5 had an adverse event after discharge, and roughly two-thirds of those events involved medications. For the Accredited Case Manager - Registered Nurse (ACM-RN), mastering structured, evidence-based care transition models is essential not only to safeguard patient safety and mitigate 30-day readmissions, but also to fulfill the core mandates of Domain II in health delivery system case management.


Evidence-Based Care Transition Frameworks

Over the past two decades, three primary evidence-based transition frameworks have achieved national validation and widespread adoption across American health systems: Project RED (Re-Engineered Discharge), the Care Transitions Intervention (CTI / Coleman Model), and Project BOOST (Better Outcomes for Older adults through Safe Transitions). Each model approaches care continuity from a distinct operational and clinical angle.

Care Transition Models Comparison:
┌────────────────────────────────────────────────────────────────────────┐
│ Project RED: 12-component provider workflow + AHCP booklet + phone call│
├────────────────────────────────────────────────────────────────────────┤
│ CTI (Coleman): 4 pillars + Transition Coach + patient empowerment       │
├────────────────────────────────────────────────────────────────────────┤
│ Project BOOST: 8Ps targeted risk assessment + clinical toolkits        │
└────────────────────────────────────────────────────────────────────────┘

1. Project RED (Re-Engineered Discharge)

Developed by clinical researchers at Boston University Medical Center and funded by the Agency for Healthcare Research and Quality (AHRQ), Project RED is a standardized, hospital-based intervention designed to improve the discharge workflow, enhance patient self-management, and reduce preventable 30-day readmissions and emergency department visits. In its 2009 randomized trial, Project RED reduced combined emergency department visits and readmissions within 30 days by about 30%.

The AHRQ Project RED toolkit lists 12 components, carried out by a discharge educator, nurse, or case manager:

  1. Ascertain need for and obtain language assistance.
  2. Make appointments for follow-up care, including post-discharge tests, with attention to transportation.
  3. Plan for follow-up of results that are pending at discharge, naming the clinician responsible.
  4. Organize post-discharge outpatient services and medical equipment.
  5. Identify the correct medicines and a plan for the patient to obtain them, including reconciliation against pre-admission medicines.
  6. Reconcile the discharge plan with national guidelines (for example, guideline-directed therapy for heart failure).
  7. Teach a written discharge plan the patient can understand: the illustrated, color-coded After Hospital Care Plan (AHCP) with appointments, a medication schedule, and warning signs.
  8. Educate the patient about the diagnosis and medicines throughout the stay, not only on the day of discharge.
  9. Review what to do if a problem arises, including whom to call.
  10. Assess the patient's understanding of the plan using teach-back.
  11. Expedite transmission of the discharge summary to the clinicians who will follow the patient.
  12. Provide telephone reinforcement of the discharge plan: a nurse or pharmacist calls 2 to 3 days after discharge.

Important

In Project RED, the reinforcement call comes 2 to 3 days after discharge. Its purpose is to catch medication problems, confirm appointments and services, review warning signs, and intervene before a minor problem becomes a readmission.

2. Care Transitions Intervention (CTI / Coleman Model)

Developed by Eric A. Coleman, MD, MPH, the Care Transitions Intervention (CTI) is a 30-day, patient-centered, cross-setting empowerment model. Unlike traditional case management models that emphasize provider coordination, the Coleman model is rooted in adult learning theory and self-efficacy theory: its foundational philosophy is to empower the patient and family caregiver to become active directors of their own care.

The intervention is facilitated by a Transition Coach (a registered nurse or medical social worker) and consists of one inpatient hospital visit, one in-home visit within 48 to 72 hours of discharge, and three follow-up telephone calls during the rest of the 30-day period. The intervention is structured entirely around Four Core Pillars:

  • Pillar 1: Medication Self-Management: The patient masters a system for managing medications independently, maintains an active, updated medication list, understands the purpose of each drug, and can articulate potential side effects and warning signs.
  • Pillar 2: Dynamic Personal Health Record (PHR): The patient actively manages and owns a portable, paper-based or digital Personal Health Record containing medical history, active diagnoses, red-flag symptoms, and questions for upcoming clinician appointments. The patient is coached to carry the PHR to every clinical encounter.
  • Pillar 3: Timely Primary Care / Specialty Follow-Up: The patient understands the importance of attending post-acute appointments, is empowered to schedule their own follow-ups, and learns how to formulate and present key clinical questions directly to the physician.
  • Pillar 4: Knowledge of Condition-Specific "Red Flags": The patient and family learn to recognize early symptoms indicating that their condition is worsening, understand the exact action steps required, and know whom to contact immediately before symptoms require emergency hospitalization.

3. Project BOOST (Better Outcomes for Older adults through Safe Transitions)

Initiated by the Society of Hospital Medicine (SHM), Project BOOST is a multidisciplinary, hospital-based quality improvement toolkit designed to optimize care transitions specifically for older adult populations. Project BOOST provides clinical tools to identify patients at high risk of adverse events and readmission upon presentation, deploying tailored transition bundles.

The cornerstone of Project BOOST is the 8Ps Risk Assessment Tool, which stratifies transition risk across eight distinct clinical and psychosocial domains:

BOOST 8P Risk CategoryClinical Indicators & TriggersTargeted Case Management Interventions
Problem MedicationsAnticoagulants, insulin/oral hypoglycemics, digoxin, opioids, antiarrhythmics, dual antiplatelets.Clinical pharmacist bedside medication reconciliation, focused teach-back on dosing/side effects, Meds-to-Beds delivery.
PsychologicalDepressive symptoms (positive PHQ-2/9), untreated psychiatric disorders, severe anxiety.Social work referral, psychiatric consultation, mental health community linkage, family engagement.
Principal DiagnosisHeart failure, COPD, acute myocardial infarction, pneumonia, stroke, acute renal failure.Disease-specific discharge teaching guides, structured red-flag action plans, early outpatient follow-up within 7 days.
PolypharmacyRoutine use of 5 or more active prescription medications.Regimen simplification, pillbox organizing, deprescribing review with hospitalist/pharmacist.
Poor Health LiteracyInability to read, comprehend, or act on health information; language barriers.Fifth-grade reading level materials, pictorial instructions, professional medical interpreter service, repeated teach-back.
Patient SupportPatient living alone, absent family caregivers, frail elderly spouse, evidence of caregiver strain.Home health referral, Area Agency on Aging linkage, respite care planning, community resource referral.
Prior HospitalizationsUnplanned inpatient admission or emergency department visit within the preceding 6 months.Root-cause analysis of prior readmissions, post-discharge nurse phone call at 48 hours, home health evaluation.
Palliative Care NeedsAdvanced life-limiting illness, severe frailty, progressive functional decline, recurrent crisis visits.Inpatient palliative care consultation, advance care planning, POLST/MOLST execution, hospice education when aligned.

Comparison of Core Care Transition Models

DimensionProject REDCare Transitions Intervention (CTI)Project BOOST
Originating BodyBoston University / AHRQEric Coleman, MD / Univ. of ColoradoSociety of Hospital Medicine (SHM)
Core PhilosophyHospital workflow re-engineering and structured provider discharge executionPatient empowerment, coaching, and self-efficacyMultidisciplinary risk screening and targeted quality toolkits
Key ToolAfter-Hospital Care Plan (AHCP) bookletPersonal Health Record (PHR) & 4 Pillars8Ps Risk Assessment Tool
Intervention ScopeInpatient stay + 48–72 hr phone callInpatient visit + home visit + 3 phone calls over 30 daysInpatient risk stratification and disease-specific care bundles
Primary RoleDischarge Educator / RN Case ManagerTransition Coach (RN or MSW)Interprofessional Care Team & Hospitalist

Discharge Medication Reconciliation and Meds-to-Beds Programs

Medication discrepancies are the leading cause of post-discharge adverse drug events (ADEs). The Joint Commission requires a systematic medication reconciliation process at transitions of care (NPSG.03.06.01 through 2025; for hospitals, now part of the 2026 National Performance Goals).

The Five-Step Medication Reconciliation Process

  1. Develop a comprehensive pre-admission medication list: Interview the patient/family, inspect home medication vials, and verify pharmacy fill records and electronic health information exchanges (HIEs) to capture prescription drugs, over-the-counter (OTC) products, vitamins, and herbal supplements.
  2. Develop a list of newly ordered inpatient medications: Review active acute treatments administered during the hospital stay.
  3. Compare pre-admission medications against inpatient orders: Systematically cross-reference both lists to identify intentional modifications versus unintentional omissions, duplications, dosing errors, or contraindications.
  4. Make clinical decisions based on the comparison: Collaborate with the attending physician and clinical pharmacist to finalize the post-discharge regimen, ensuring stopped medications are explicitly documented as discontinued.
  5. Communicate the finalized regimen: Provide the reconciled medication list to the patient, caregiver, community pharmacy, and next-level care providers (primary care, home health, or skilled nursing facility).

Resolving Financial and Authorization Barriers

A technically perfect discharge medication reconciliation is useless if the patient cannot afford or obtain the medications upon leaving the hospital. Case managers must proactively address:

  • Prior Authorizations (PAs): Specialty drugs (e.g., direct-acting oral anticoagulants [DOACs], heart failure SGLT2 inhibitors, GLP-1 receptor agonists) frequently require payer prior authorization. Initiating PAs 24 to 48 hours prior to anticipated discharge prevents patients from arriving at retail pharmacies only to face claim rejections.
  • High Out-of-Pocket Copayments: For commercial patients, case managers leverage manufacturer copay assistance cards. For Medicare beneficiaries (where copay cards are legally prohibited under the federal Anti-Kickback Statute), case managers connect patients to disease-specific charitable foundations (e.g., Patient Access Network Foundation, HealthWell Foundation).
  • 340B Drug Pricing Programs: Eligible safety-net and disproportionate share hospitals can use 340B savings to offer low-cost medications to eligible low-income or uninsured patients through hospital pharmacies.

Bedside Medication Delivery ("Meds-to-Beds") Programs

Meds-to-Beds programs represent a proven operational model that eliminates post-discharge pharmacy fill barriers. Under this protocol, the hospital's outpatient pharmacy processes, fills, and delivers discharge prescriptions directly to the patient's bedside prior to physical discharge.

Key clinical advantages of Meds-to-Beds include:

  • First-Fill Assurance: Verifies that the patient physically has essential medications before leaving the hospital.
  • Bedside Pharmacist / Nurse Consultation: Allows face-to-face medication education, ensuring the patient demonstrates correct inhaler technique, insulin pen administration, or subcutaneous anticoagulant injection.
  • Real-Time Adjudication: Financial rejections, high copayments, and prior authorization deficits are identified and resolved while the attending medical team is still accessible to adjust therapies if necessary.

Discharge Teach-Back Methodology

Traditional discharge education that relies on passive questions such as "Do you understand?" or "Do you have any questions?" often misses misunderstanding. Patients frequently nod out of embarrassment, deference, or cognitive overload.

The Teach-Back method (also known as the "show-me" method) is a structured, evidence-based communication technique where the clinician assesses patient comprehension by asking the patient or caregiver to state in their own words or demonstrate what they need to know or do.

The Closed-Loop Teach-Back Cycle:
┌────────────────────────────────────────────────────────┐
│ Clinician Explains 1-2 Key Concepts ("Chunk")         │
└──────────────────────────┬─────────────────────────────┘
                           │
                           ▼
┌────────────────────────────────────────────────────────┐
│ Clinician Assesses Comprehension ("Check")            │
│ "To make sure I was clear, tell me how you'll take..."│
└──────────────────────────┬─────────────────────────────┘
                           │
            ┌──────────────┴──────────────┐
            ▼                             ▼
    [Patient Explains]           [Patient Struggles]
            │                             │
            ▼                             ▼
┌────────────────────────┐   ┌───────────────────────────┐
│ Comprehension Confirmed│   │ Re-teach Using New Words, │
│ Move to Next Concept   │   │ Then Re-assess Teach-Back │
└────────────────────────┘   └───────────────────────────┘

Key Principles of Effective Teach-Back

  • Chunk and Check: Never overload the patient with the entire discharge packet at once. Deliver instructions in small, digestible "chunks" of 1 to 2 key points, and immediately "check" comprehension before moving forward.
  • Shift the Burden to the Clinician: Frame the prompt so the patient does not feel tested or interrogated. Use phrasing such as: "I want to make sure I gave you clear instructions today. When your daughter asks you tonight how you are supposed to take this water pill, what will you tell her?"
  • Action-Oriented Prompts: Focus teach-back on high-stakes execution: medication dosing/timing, red-flag symptoms, what specific phone number to call, and return precautions.
  • Show-Me Demonstrations: For devices (glucometers, incentive spirometers, subcutaneous enoxaparin injections, wound dressings), require the patient or caregiver to physically manipulate and demonstrate proper technique.
  • Closed-Loop Remediation: If the patient demonstrates incomplete or incorrect understanding, the case manager must re-teach the concept using alternative words or visual aids, and subsequently re-assess comprehension until closed-loop mastery is achieved.
Test Your Knowledge

Under the Project RED (Re-Engineered Discharge) framework, when is the post-discharge reinforcement telephone call made, and what is its main purpose?

A

About 2 to 3 days after discharge, to reinforce the plan and catch medication, appointment, and symptom problems

B

Within 24 hours of discharge, to make sure the patient has contacted the commercial insurer for any required pre-authorization

C

Seven calendar days after discharge, timed to coincide with the primary care provider's first scheduled clinic appointment

D

Fourteen calendar days after discharge, to estimate 30-day readmission risk and complete the hospital's billing documentation

Test Your Knowledge

A case manager is implementing the Care Transitions Intervention (CTI / Coleman Model) for an older adult with chronic obstructive pulmonary disease. Which operational strategy reflects the core philosophical underpinning of this model?

A

The case manager schedules all outpatient appointments, orders home medications, and directly manages all follow-up logistics on the patient's behalf

B

The Transition Coach empowers the patient and caregiver across 30 days to use a Personal Health Record, master medication self-management, and recognize red flags

C

The hospitalist team conducts mandatory weekly telemedicine visits for 60 days following acute discharge

D

The bedside nurse completes an 8Ps risk assessment to determine whether the patient qualifies for inpatient palliative care

Test Your Knowledge

In the Project BOOST framework, which clinical risk factor from the 8Ps assessment tool is paired with the most appropriate targeted transitional intervention?

A

Polypharmacy (≥5 medications) is managed by transferring the patient to an inpatient hospice facility

B

Psychological distress (PHQ-9 positive) is addressed by eliminating all post-acute physical therapy orders

C

Problem medications, such as anticoagulants or insulin, call for pharmacist reconciliation, bedside delivery, and teach-back

D

Poor Health Literacy is addressed by providing the complete 30-page electronic health record discharge summary directly to the patient

Test Your Knowledge

When utilizing the discharge teach-back method to verify an older adult's understanding of a new oral anticoagulant regimen, which clinician action represents correct evidence-based technique?

A

Asking the patient, 'Do you understand how to take your new blood thinner every morning?' and accepting a nod as verification

B

Reviewing all 14 discharge medications simultaneously in a single 45-minute lecture at the time of discharge

C

Documenting that education was completed because the patient signed the standardized hospital discharge instruction packet

D

Chunk the teaching and ask, "To be sure I explained it clearly, what bleeding signs would make you call us?"

Sections you finish are checked off in the contents.