6.9 Regional Musculoskeletal Syndromes, Back Pain & Sports Injuries

Key Takeaways

  • Back pain, shoulder, elbow, wrist and hand, hip and pelvic, knee, foot and ankle syndromes and other bursitis are the enumerated regional musculoskeletal topics.
  • Imaging is not indicated for acute low back pain without red flags, because incidental findings are common and do not change management.
  • Cauda equina syndrome with urinary retention, saddle anesthesia and bilateral leg weakness requires emergent magnetic resonance imaging and surgical decompression.
  • Rotator cuff tendinopathy produces painful abduction with preserved passive range, whereas adhesive capsulitis restricts passive range as well.
  • Trochanteric pain syndrome from gluteal tendinopathy is the usual cause of lateral hip pain and is often misattributed to true bursitis.
Last updated: August 2026

1. Low Back Pain

The first task is triage into three categories: non-specific mechanical pain (about 85%), radiculopathy or spinal stenosis, and serious underlying pathology (well under 5%).

Red flags that change management

Red flagConcern
Urinary retention, saddle anesthesia, bilateral leg weakness, bowel incontinenceCauda equina syndrome — emergent MRI and decompression
Fever, injection drug use, recent bacteremia, indwelling deviceVertebral osteomyelitis or epidural abscess
History of cancer, unexplained weight loss, pain at night or at restMetastatic disease
Age over 70, osteoporosis, chronic corticosteroid use, minor traumaCompression fracture
Progressive or severe neurologic deficitCord or root compromise

Without red flags, do not image. Early imaging does not improve outcomes, and degenerative findings are ubiquitous in asymptomatic adults — disc bulges and facet arthropathy are present in most people over 50. Imaging generates procedures rather than answers.

Management of non-specific pain: remain active (bed rest worsens outcomes), heat, NSAIDs or acetaminophen, and physical therapy for persistent symptoms. Opioids and systemic corticosteroids are not indicated for acute non-specific back pain.

Nerve root syndromes and spinal stenosis

These are enumerated in the blueprint under Neurology as nerve root syndromes and mechanical lesions of the spine.

RootMotorSensoryReflex
L4Knee extension, dorsiflexionMedial calfPatellar
L5Great toe dorsiflexion, foot eversionDorsum of foot, lateral legNone
S1Plantar flexionLateral foot, soleAchilles

Lumbar spinal stenosis produces neurogenic claudication: bilateral buttock and leg pain worsened by standing and walking, relieved by sitting or lumbar flexion. Patients report walking further when leaning on a shopping cart. The critical contrast is with vascular claudication, which is relieved by standing still, is not posture-dependent, and comes with diminished pulses and a reduced ankle-brachial index.

2. Shoulder

ConditionKey finding
Rotator cuff tendinopathy / impingementPainful arc of abduction; passive range preserved; positive Neer and Hawkins tests
Rotator cuff tearWeakness on empty-can (supraspinatus) test; inability to hold arm elevated (drop-arm sign)
Adhesive capsulitisLoss of passive as well as active range, especially external rotation; associated with diabetes and thyroid disease
Biceps tendinopathyAnterior shoulder pain; positive Speed test
Acromioclavicular osteoarthritisFocal tenderness at the joint; pain on cross-body adduction
Glenohumeral osteoarthritisCrepitus, global restriction, radiographic joint space loss

The single most useful discriminator is passive range of motion. Preserved passive range with painful active motion indicates a cuff or bursal problem; restricted passive range indicates capsular or glenohumeral disease.

3. Elbow, Wrist and Hand

  • Lateral epicondylosis (tennis elbow): pain over the lateral epicondyle, worse with resisted wrist extension. Overwhelmingly the more common of the two.
  • Medial epicondylosis (golfer elbow): pain with resisted wrist flexion and pronation.
  • Olecranon bursitis: fluctuant posterior swelling. Aspirate if warm, red or febrile — septic bursitis is common here.
  • De Quervain tenosynovitis: radial wrist pain; positive Finkelstein test; classic in new parents and in repetitive thumb use.
  • Carpal tunnel syndrome: nocturnal paresthesia in the median distribution with thenar wasting in advanced disease. Associations include pregnancy, hypothyroidism, diabetes, obesity, acromegaly and amyloidosis. Nocturnal wrist splinting is first-line.
  • Dupuytren contracture: painless palmar fascial cords with flexion contracture, most often of the fourth and fifth digits.
  • Trigger finger: catching or locking with a palpable A1 pulley nodule.

4. Hip and Pelvis

Localizing the pain determines the differential, and this is the reasoning the exam rewards:

LocationLikely source
GroinTrue hip joint — osteoarthritis, osteonecrosis, femoral neck fracture, labral tear
LateralGreater trochanteric pain syndrome — gluteus medius/minimus tendinopathy
Posterior / buttockLumbar spine referral, sacroiliac joint, ischial bursitis

Lateral hip pain is rarely true bursitis. It is usually gluteal tendinopathy, and the term greater trochanteric pain syndrome reflects that. It responds to load management and eccentric strengthening rather than to repeated injection.

Meralgia paresthetica — burning numbness over the anterolateral thigh from lateral femoral cutaneous nerve compression — is purely sensory with no weakness and no reflex change. It is associated with obesity, tight belts and pregnancy, and it is enumerated in the blueprint under peripheral neuropathy.

5. Knee

ConditionKey finding
Meniscal tearJoint-line tenderness, mechanical locking or catching, positive McMurray test
Anterior cruciate ligament tearAudible pop, immediate hemarthrosis, positive Lachman test (most sensitive)
Medial collateral ligament injuryLaxity with valgus stress at 30 degrees of flexion
Patellofemoral painAnterior pain worse with stairs and prolonged sitting; young, often female
Pes anserine bursitisTenderness 4 to 5 cm below the medial joint line
Prepatellar bursitisAnterior swelling from kneeling; consider septic bursitis
Baker cystPopliteal fullness; rupture mimics deep vein thrombosis

Rapid effusion after injury: blood within two hours indicates anterior cruciate ligament tear, osteochondral fracture or patellar dislocation. Slower effusion over a day is more typical of meniscal injury.

The Ottawa knee rules identify who needs radiography after acute injury: age 55 or older, isolated patellar tenderness, fibular head tenderness, inability to flex to 90 degrees, or inability to bear weight for four steps both immediately and in the emergency department.

6. Foot and Ankle

  • Plantar fasciitis: heel pain worst with the first steps in the morning and after rest; point tenderness at the medial calcaneal tubercle. Treated with stretching, supportive footwear and load reduction. Imaging is unnecessary, and heel spurs are incidental.
  • Achilles tendinopathy: posterior heel pain; fluoroquinolone use is a recognized precipitant of tendinopathy and rupture.
  • Achilles rupture: audible pop, palpable gap, positive Thompson test (no plantar flexion on calf squeeze).
  • Morton neuroma: burning pain in the third web space with a palpable click on lateral compression.
  • Tarsal tunnel syndrome: burning plantar pain from posterior tibial nerve compression.

The Ottawa ankle rules limit unnecessary radiography: image only with bone tenderness at the posterior edge or tip of either malleolus, tenderness at the navicular or base of the fifth metatarsal, or inability to bear weight for four steps.

7. Sports Injuries and Trauma

A separately enumerated blueprint subsection. The internist-facing points:

  • Overuse injuries — stress fracture, tendinopathy, medial tibial stress syndrome — result from training errors, most commonly a rapid increase in volume or intensity. Stress fractures are frequently invisible on initial radiographs; MRI is the sensitive test, and a normal early film does not exclude one.
  • The female athlete triad / relative energy deficiency in sport — low energy availability, menstrual dysfunction and low bone density — is a cause of stress fractures in young women and requires nutritional rather than orthopedic management.
  • Concussion is a clinical diagnosis; imaging is normal. Return to play follows a graduated protocol, and an athlete should never return the same day.
  • Exertional rhabdomyolysis presents with severe muscle pain, weakness and dark urine after unaccustomed exertion; treatment is aggressive intravenous fluid.
  • Exercise-associated hyponatremia results from excessive hypotonic fluid intake during endurance events and is treated with hypertonic saline, not with more free water.
Test Your Knowledge

A 68-year-old man reports bilateral buttock and posterior thigh pain that begins after walking about two blocks. The pain resolves when he sits down and he notices he can walk much farther when pushing a shopping cart. Pedal pulses are normal and the ankle-brachial index is 1.05. What is the most likely diagnosis?

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Test Your Knowledge

A 34-year-old recreational runner has three weeks of progressively worsening anterior shin pain that is now present at rest, after increasing her weekly mileage from 10 to 30 miles over one month. Point tenderness is present over the anterior tibia. Plain radiographs of the tibia are normal. What is the most appropriate next step?

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