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100+ Free FRCPath Haematology Practice Questions

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2026 Statistics

Key Facts: FRCPath Haematology Exam

125

Part 1 Paper 2 questions

RCPath Haematology examination page

50 + 75

Best-from-five MCQs plus EMQs in Paper 2

RCPath Haematology examination page

3 days

Part 2 examination duration

RCPath Haematology examination page

GBP 749

2026 Part 1 fee

RCPath fees for examinations 2026

FRCPath Haematology has Part 1 and Part 2 examinations. Part 1 consists of two 3-hour written papers: Paper 1 has four compulsory essays across transfusion, general haematology, haematological oncology and haemostasis/thrombosis; Paper 2 has 125 questions in 3 hours, split into 50 best-from-five MCQs and 75 EMQs. Part 2 is held over 3 days and includes morphology short answer questions and long cases, transfusion, coagulation and two 30-minute oral examinations. The 2026 RCPath fee list gives Haematology Part 1 as GBP 749 and Part 2 as GBP 1,576.

Sample FRCPath Haematology Practice Questions

Try these sample questions to test your FRCPath Haematology exam readiness. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1Microcytosis with low ferritin and raised total iron binding capacity most strongly indicates which diagnosis?
A.Iron deficiency anaemia
B.Beta thalassaemia trait
C.Vitamin B12 deficiency
D.Folate deficiency
Explanation: Iron deficiency typically causes microcytosis, low ferritin and raised TIBC because iron stores are depleted.
2Microcytosis with normal ferritin and raised HbA2 is most consistent with which condition?
A.Vitamin B12 deficiency
B.Beta thalassaemia trait
C.Folate deficiency
D.G6PD deficiency
Explanation: Beta thalassaemia trait produces disproportionate microcytosis and classically raises HbA2.
3Macrocytosis with hypersegmented neutrophils, glossitis and posterior column signs points to which deficiency?
A.Folate deficiency
B.G6PD deficiency
C.Vitamin B12 deficiency
D.Hereditary spherocytosis
Explanation: Vitamin B12 deficiency causes megaloblastic anaemia and may cause neurological dysfunction.
4Macrocytosis in a malnourished patient without neurological signs is most consistent with which deficiency?
A.G6PD deficiency
B.Hereditary spherocytosis
C.Warm autoimmune haemolytic anaemia
D.Folate deficiency
Explanation: Folate deficiency causes megaloblastic anaemia but does not usually cause the neurological syndrome of B12 deficiency.
5Bite cells after an oxidant drug exposure are most typical of which disorder?
A.G6PD deficiency
B.Hereditary spherocytosis
C.Warm autoimmune haemolytic anaemia
D.Paroxysmal nocturnal haemoglobinuria
Explanation: G6PD deficiency predisposes red cells to oxidant damage, Heinz body formation and bite cells.
6Spherocytes, splenomegaly and reduced eosin-5-maleimide binding support which inherited disorder?
A.Warm autoimmune haemolytic anaemia
B.Hereditary spherocytosis
C.Paroxysmal nocturnal haemoglobinuria
D.Acute chest syndrome
Explanation: Reduced EMA binding supports a red cell membrane defect such as hereditary spherocytosis.
7A positive direct antiglobulin test for IgG with spherocytes best supports which diagnosis?
A.Paroxysmal nocturnal haemoglobinuria
B.Acute chest syndrome
C.Warm autoimmune haemolytic anaemia
D.Hereditary haemochromatosis
Explanation: Warm autoimmune haemolysis is usually IgG mediated and causes extravascular haemolysis.
8Loss of CD55 and CD59 on flow cytometry is diagnostic of which haemolytic disorder?
A.Acute chest syndrome
B.Hereditary haemochromatosis
C.Aplastic anaemia
D.Paroxysmal nocturnal haemoglobinuria
Explanation: PNH is diagnosed by deficiency of GPI-anchored proteins such as CD55 and CD59.
9Fever, hypoxia and a new pulmonary infiltrate in sickle cell disease indicate which complication?
A.Acute chest syndrome
B.Hereditary haemochromatosis
C.Aplastic anaemia
D.Pure red cell aplasia
Explanation: Acute chest syndrome is a sickle emergency defined by respiratory symptoms or hypoxia with a new infiltrate.
10High transferrin saturation, raised ferritin and HFE C282Y homozygosity support which diagnosis?
A.Aplastic anaemia
B.Hereditary haemochromatosis
C.Pure red cell aplasia
D.Microangiopathic haemolytic anaemia
Explanation: HFE haemochromatosis causes increased iron absorption with high transferrin saturation and iron overload.

About the FRCPath Haematology Exam

FRCPath Haematology is the Royal College of Pathologists fellowship examination pathway for haematology specialty trainees. It assesses knowledge, laboratory interpretation, clinical judgement and consultant-level decision making across general haematology, haematological oncology, haemostasis and thrombosis, and transfusion medicine.

Assessment

Part 1 has two 3-hour written papers: four essays and a 125-question MCQ/EMQ paper. Part 2 is held over 3 days with morphology short answers and long cases, transfusion, coagulation and oral examinations.

Time Limit

Part 1 Paper 1 3 hours; Part 1 Paper 2 3 hours; Part 2 over 3 days with morphology, transfusion, coagulation and two 30-minute oral examinations.

Passing Score

Part 1 requires passing both papers at a single sitting; Paper 2 uses Angoff standard setting. Part 2 requires passing all three written components and demonstrating oral competence at one sitting.

Exam Fee

2026 RCPath fees: Haematology Part 1 GBP 749; Part 2 GBP 1,576. (Royal College of Pathologists)

FRCPath Haematology Exam Content Outline

About 25% of Part 1 Paper 2

General and Laboratory Haematology

Anaemia, red cell disorders, haemolysis, marrow failure, paediatric and obstetric haematology, laboratory practice and quality.

About 25% of Part 1 Paper 2

Haematological Oncology

Acute leukaemia, myeloproliferative neoplasms, MDS, lymphoma, plasma cell disorders, molecular diagnostics and risk assessment.

About 25% of Part 1 Paper 2

Haemostasis and Thrombosis

Inherited and acquired bleeding disorders, platelet disorders, thrombophilia, anticoagulation, DIC and thrombotic emergencies.

About 25% of Part 1 Paper 2

Transfusion Medicine

Compatibility testing, component selection, transfusion reactions, alloimmunisation, pregnancy antibodies and massive transfusion support.

Integrated across papers

Therapeutics and Supportive Care

Chemotherapy, targeted therapy, stem cell transplantation, growth factors, infection prevention, anticoagulants and patient blood management.

Part 2 and laboratory practice

Morphology, Diagnostics and Governance

Blood film and marrow interpretation, flow cytometry, cytogenetics, MRD, sample identity, EQA, critical results and clinical communication.

How to Pass the FRCPath Haematology Exam

What You Need to Know

  • Passing score: Part 1 requires passing both papers at a single sitting; Paper 2 uses Angoff standard setting. Part 2 requires passing all three written components and demonstrating oral competence at one sitting.
  • Assessment: Part 1 has two 3-hour written papers: four essays and a 125-question MCQ/EMQ paper. Part 2 is held over 3 days with morphology short answers and long cases, transfusion, coagulation and oral examinations.
  • Time limit: Part 1 Paper 1 3 hours; Part 1 Paper 2 3 hours; Part 2 over 3 days with morphology, transfusion, coagulation and two 30-minute oral examinations.
  • Exam fee: 2026 RCPath fees: Haematology Part 1 GBP 749; Part 2 GBP 1,576.

Keys to Passing

  • Complete 500+ practice questions
  • Score 80%+ consistently before scheduling
  • Focus on highest-weighted sections
  • Use our AI tutor for tough concepts

FRCPath Haematology Study Tips from Top Performers

1Map every revision session to one of the four RCPath blueprint areas: general/lab haematology, oncology, haemostasis/thrombosis and transfusion.
2Practise explaining diagnostic reasoning from blood films, marrow findings, coagulation screens and transfusion investigations.
3For Part 1 essays, rehearse structured answers that link pathogenesis, investigation, management and patient safety.
4For Part 2, practise short data interpretation answers under time pressure and verbalise oral-exam style management plans.
5Track errors by failure mode: factual gap, wrong differential, unsafe management, missed laboratory artefact or weak communication.

Frequently Asked Questions

What is FRCPath Haematology?

It is the Royal College of Pathologists fellowship examination pathway in haematology, used in UK specialty training and designed to assess knowledge, skills, behaviour and consultant-level clinical judgement.

What is the Part 1 format?

Part 1 has two 3-hour written papers. Paper 1 contains four compulsory essays. Paper 2 contains 125 questions: 50 best-from-five MCQs and 75 EMQs.

What does Part 1 Paper 2 cover?

RCPath states that blood transfusion, general haematology including laboratory management, haematological oncology and haemostasis/thrombosis each make up about 25% of the examination.

What is the Part 2 format?

Part 2 is held over 3 days and includes morphology short answers and long cases, transfusion data interpretation, coagulation data interpretation and two structured oral examinations.

Does this bank exactly reproduce the RCPath exam?

No. The site-wide bank provides 100 four-option practice MCQs aligned to the official blueprint. It supports MCQ and clinical reasoning revision but does not replace essay, morphology, data interpretation or viva practice.