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Key Facts: Test Ammissione Professioni Sanitarie Exam

60 questions

Total questions on the official examination

MUR Decreto Ministeriale

100 minutes

Total examination time limit

MUR Decreto Ministeriale

23 of 60

Biology questions (38.3% of official test)

MUR Ministerial Syllabus

15 of 60

Chemistry questions (25.0% of official test)

MUR Ministerial Syllabus

13 of 60

Physics and Mathematics questions (21.7% of official test)

MUR Ministerial Syllabus

+1.5 / -0.4

Scoring: +1.5 correct, -0.4 wrong, 0 unanswered

MUR Decreto Ministeriale

90 points

Maximum possible exam score

MUR Decreto Ministeriale

September

Annual national test window

Universitaly / MUR

The Test di Ammissione alle Professioni Sanitarie is Italy's official 60-question, 100-minute entrance exam for degree courses in nursing, physiotherapy, radiology, and allied healthcare disciplines. Administered annually in September under MUR decree, ranking is determined out of a 90-point maximum (+1.5 correct, -0.4 wrong, 0 blank).

Sample Test Ammissione Professioni Sanitarie Practice Questions

Try these sample questions to review concepts for the Test Ammissione Professioni Sanitarie exam. Each question includes a detailed explanation. Start the interactive quiz above for the full 100+ question experience with AI tutoring.

1According to the fluid mosaic model (modello a mosaico fluido) of Singer and Nicolson, what is the fundamental structural matrix of the eukaryotic plasma membrane?
A.A rigid monolayer of saturated triglycerides interspersed with cellulose fibrils
B.A phospholipid bilayer with hydrophobic hydrocarbon tails facing inward and hydrophilic phosphate heads facing the aqueous environments
C.A continuous external protein shell surrounding an internal non-polar paraffin core
D.A peripheral carbohydrate meshwork anchoring insoluble cholesterol polymers
Explanation: The plasma membrane is organized as an amphipathic phospholipid bilayer (doppio strato fosfolipidico). The polar, hydrophilic phosphate heads interact with the aqueous extracellular and cytosolic fluids, while the non-polar fatty acid tails face inward to form a hydrophobic interior.
2In human physiology, the primary active transport mechanism operated by the sodium-potassium pump (pompa Na+/K+ ATPasi) transports ions across the plasma membrane in which stoichiometric ratio per molecule of ATP hydrolyzed?
A.2 Na+ ions exported, 2 K+ ions imported
B.3 Na+ ions imported, 2 K+ ions exported
C.3 Na+ ions exported, 2 K+ ions imported
D.1 Na+ ion exported, 3 K+ ions imported
Explanation: The Na+/K+ ATPase is an electrogenic primary active transporter that couples the hydrolysis of one ATP molecule to the extrusion of 3 Na+ ions out of the cell and the influx of 2 K+ ions into the cell, both moving against their electrochemical gradients.
3Lysosomes (lisosomi) are intracellular organelles containing acid hydrolases. Which physiological condition is essential for the optimal enzymatic activity of these degradative enzymes?
A.A neutral lumen maintained at pH 7.2 by bicarbonate exchangers
B.An acidic lumen maintained at approximately pH 4.5–5.0 by an ATP-dependent proton pump (H+ ATPase)
C.An alkaline environment at pH 8.5 generated by calcium accumulation
D.A totally anhydrous lumen devoid of free water molecules
Explanation: Lysosomal enzymes (acid hydrolases, including nucleases, proteases, and lipases) require an acidic luminal environment (pH ~4.5–5.0) maintained by vacuolar H+-ATPases that pump protons into the organelle. This acid optimum acts as an intracellular safeguard against accidental autolysis should a lysosome rupture in the neutral cytosol (pH ~7.2).
4Which organelle is primarily responsible for the post-translational modification, terminal glycosylation, and sorting of secretory and lysosomal proteins received from the rough endoplasmic reticulum?
A.Golgi apparatus (apparato del Golgi)
B.Smooth endoplasmic reticulum (reticolo endoplasmatico liscio)
C.Peroxisome (perossisoma)
D.Nucleolus (nucleolo)
Explanation: The Golgi apparatus consists of flattened cisternae (cis-, medial-, and trans-cisternae) that receive cargo proteins from the rough endoplasmic reticulum (RER), modify their oligosaccharide side chains (O-linked and complex N-linked glycosylation), tag them (e.g., mannose-6-phosphate for lysosomes), and sort them into transport vesicles.
5Colchicine is an antimitotic alkaloid that binds to tubulin heterodimers and arrests eukaryotic cells in metaphase. Which cytoskeletal structures are prevented from polymerizing by this substance?
A.Intermediate filaments composed of cytokeratins
B.Actin microfilaments forming the contractile ring
C.Microtubules (microtubuli) composing the mitotic spindle
D.Collagen triple helices of the extracellular matrix
Explanation: Microtubules are cylindrical polymers of alpha- and beta-tubulin heterodimers that assemble the mitotic spindle (fuso mitotico). Colchicine prevents microtubule polymerization, inhibiting spindle formation and arresting cells at metaphase.
6Which piece of biological evidence strongly supports the endosymbiotic theory (teoria endosimbiontica) regarding the evolutionary origin of mitochondria in eukaryotic cells?
A.Mitochondria synthesize histones to pack their linear nuclear chromosomes
B.Mitochondria possess their own circular double-stranded DNA and 70S-like ribosomes that are sensitive to bacterial antibiotics
C.Mitochondrial outer membranes are identical in lipid composition to plant cell walls
D.Mitochondria divide synchronously with nuclear mitosis via cleavage furrows made of actin
Explanation: Mitochondria contain their own circular double-stranded genome (mtDNA) without histones and ribosomes similar in size (70S) and antibiotic sensitivity to those of prokaryotes. They replicate by binary fission, supporting their origin from ancestral endosymbiotic aerobic proteobacteria.
7During which phase of somatic mitosis do sister chromatids (cromatidi fratelli) disjoin and migrate toward opposite poles of the dividing cell?
A.Prophase (profase)
B.Metaphase (metafase)
C.Anaphase (anafase)
D.Telophase (telofase)
Explanation: During anaphase, cohesin complexes holding sister chromatids together are cleaved by separase, and the kinetochore microtubules shorten, pulling the separated chromatids (now individual daughter chromosomes) toward opposite spindle poles.
8In which sub-stage of meiotic prophase I does genetic recombination via crossing-over between non-sister chromatids of homologous chromosomes take place?
A.Leptotene
B.Zygotene
C.Pachytene (pachitene)
D.Diakinesis
Explanation: During the pachytene sub-stage of prophase I, homologous chromosomes are fully synapsed via the synaptonemal complex (formed during zygotene), and reciprocal exchange of genetic material (crossing-over) occurs at recombination nodules.
9During semi-conservative DNA replication in human cells, which enzyme is responsible for linking Okazaki fragments on the lagging strand by catalyzing phosphodiester bond formation?
A.DNA topoisomerase (gyrase)
B.DNA helicase
C.DNA ligase (DNA ligasi)
D.RNA primase
Explanation: DNA ligase catalyzes the creation of a phosphodiester bond between the 3'-OH group of one DNA segment and the 5'-phosphate group of the adjacent segment, effectively sealing the nicks between Okazaki fragments on the lagging strand.
10What is the primary function of the spliceosome (spliceosoma) during the maturation of pre-mRNA in eukaryotic cell nuclei?
A.Adding a 7-methylguanosine cap to the 5' terminus of the transcript
B.Excision of non-coding introns and ligation of coding exons
C.Attachment of a poly-A tail to the 3' untranslated region
D.Translation of nucleotide triplets into nascent polypeptide chains
Explanation: The spliceosome is a large ribonucleoprotein complex composed of small nuclear RNAs (snRNAs) and proteins that identifies consensus splicing sequences, removes non-coding regions (introns), and splices coding sequences (exons) together to generate mature mRNA.

About the Test Ammissione Professioni Sanitarie Exam

The Test di Ammissione ai Corsi di Laurea delle Professioni Sanitarie is Italy's official university admissions examination governed by the Ministry of University and Research (MUR) for entry into three-year healthcare profession bachelor's degree courses (Classi L/SNT1, L/SNT2, L/SNT3, and L/SNT4). Each university prepares and administers its examination on the national date under the ministerial rules. In 2026/2027 MUR scheduled separate Italian- and English-language tests. The official examination consists of 60 multiple-choice questions with five options, delivered in 100 minutes across biology (23 questions), chemistry (15 questions), physics and mathematics (13 questions), logical reasoning (5 questions), and reading skills and general culture (4 questions). Scoring awards +1.5 points for each correct answer, -0.4 points for incorrect answers, and 0 points for blank responses; candidates scoring 0 or below are not included in the merit ranking. Independent Test Professioni Sanitarie practice by OpenExamPrep provides 100 English-language, four-option study questions built around the official topics. It is not an official translation, item set, or format simulation.

Exam sponsor: Ministero dell'Università e della Ricerca (MUR) / individual universities. The requirements and fees below concern the certification or admission exam, separate from our free practice resources.

Assessment

60 multiple-choice questions delivered in a single 100-minute session: 23 biology, 15 chemistry, 13 physics and mathematics, 5 logical reasoning, and 4 reading skills and general culture. Scoring: +1.5 correct, -0.4 wrong, 0 unanswered; maximum score 90 points.

Time Limit

100 minutes

Passing Score

University-specific merit ranking; candidates must score more than 0 (+1.5 correct, -0.4 wrong, 0 blank)

Exam / Certification Fees

Varies by university admission notice

Exam sponsor website

Our practice resources: topics covered

We aim to reflect publicly available exam outlines and topic information in our study resources. Coverage, format, and difficulty may differ from the actual exam, and we cannot guarantee that every detail is accurate or current. Confirm exam requirements, fees, and policies with the official exam sponsor.

38%

Biology

Cellular biology, genetics, Mendelian inheritance, DNA/RNA, human anatomy and organ systems, bioenergetics, photosynthesis, and cellular respiration

25%

Chemistry

Atomic structure, periodic table trends, chemical bonds, stoichiometry, solutions and molarity, acids and bases, pH, thermodynamics, and organic chemistry

22%

Physics and Mathematics

Kinematics, Newton's laws, fluids and pressure, thermodynamics, electrostatics and circuits, algebra, functions, geometry, trigonometry, and probability

8%

Logical Reasoning and Problem Solving

Syllogisms, verbal logic, sequence completion, deductive scenarios, and conditional problem solving

7%

Reading Comprehension and General Culture

Passage analysis, textual inferences, vocabulary in scientific and humanist contexts, and historical-civic awareness

Preparing for the Test Ammissione Professioni Sanitarie Exam

What You Need to Know

  • Passing score: University-specific merit ranking; candidates must score more than 0 (+1.5 correct, -0.4 wrong, 0 blank)
  • Assessment: 60 multiple-choice questions delivered in a single 100-minute session: 23 biology, 15 chemistry, 13 physics and mathematics, 5 logical reasoning, and 4 reading skills and general culture. Scoring: +1.5 correct, -0.4 wrong, 0 unanswered; maximum score 90 points.
  • Time limit: 100 minutes
  • Exam / certification fees: Varies by university admission notice Official sources

Using Our Practice Resources

  • Work through all 100 available questions
  • Review every answer and explanation
  • Track weak areas and revisit them
  • Use our AI tutor for tough concepts

Test Ammissione Professioni Sanitarie: Suggested Study Strategy

1Biology and Chemistry together represent 63% of the total questions (38 out of 60) — dedicate the majority of revision time to cellular metabolism, organ physiology, stoichiometry, and functional groups.
2Because wrong answers incur a -0.4 point penalty, avoid random guessing; only attempt questions where you can eliminate at least two plausible distractors.
3Maintain a strict time budget of approximately 100 seconds per question, securing quick points on reading and biology before tackling multi-step calculations in chemistry and physics.
4Practice mental math and dimensional analysis regularly, as calculators and reference tables are strictly prohibited in the exam hall.
5Review human physiology and organ systems thoroughly, as allied health tests frequently include clinical and applied anatomical scenarios.

Frequently Asked Questions

What is the Test di Ammissione alle Professioni Sanitarie and who administers it?

The Test di Ammissione alle Professioni Sanitarie is the competitive entrance examination for undergraduate three-year healthcare professions courses in Italy. MUR fixes the national rules and dates, while individual universities prepare and administer their examinations and publish local merit rankings.

Which degree courses are covered by this admission examination?

The test regulates entry into four statutory classes: L/SNT1 (Infermieristica, Ostetricia), L/SNT2 (Fisioterapia, Logopedia, Terapia della Neuro e Psicomotricità dell'Età Evolutiva, Educazione Professionale), L/SNT3 (Tecniche di Radiologia Medica, Tecniche di Laboratorio Biomedico, Dietistica), and L/SNT4 (Assistenza Sanitaria, Tecniche della Prevenzione nell'Ambiente e nei Luoghi di Lavoro).

How is the exam structured, timed, and scored?

The official exam comprises 60 multiple-choice questions with five options to be answered in 100 minutes. The maximum possible score is 90 points, calculated as +1.5 points for each correct answer, -0.4 points penalty for each incorrect answer, and 0 points for omitted questions.

How do university merit rankings work for admission?

Unlike Medicine and Surgery which utilizes a single nationwide ranking list, Professioni Sanitarie candidates are ranked by individual university according to their expressed degree course preferences (prima, seconda, terza preferenza) in the local bando di concorso.

Are these practice questions official test items?

No. Independent Test Professioni Sanitarie practice by OpenExamPrep provides English-language questions based on the subject areas in the MUR decree. They are a four-option study adaptation, not an official translation, format simulation, endorsement, or set of official items.